Eruphorbia heterophylla (Gwo-Malonmen) : vertus médicinales en extraction alcoolique

Eruphorbia heterophylla (Gwo-Malonmen, Grosse Mal-nommée) — famille Euphorbiacées.

Synonymes scientifiques : Euphorbia geniculata Ortega, E prunifolia Jacq., Poinsettia geniculata (Ortega) Klotzsch & Garcke, P Heterophylla (L.) Klotzsch & Garcke..

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 8 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 42 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pimentel Da Silva U (s.d.)

     Extrait heterophylla dispersion, studies on the medicinal properties of specimens collected in Brazil are lacking.

   • Selon SUJA RANI D (2023)

     Extrait Objective: The present investigation aimed to evaluate the hepatoprotective potentials of ethanol extract of Euphorbia heterophylla leaves against ethanol-induced liver damage in rats. But in the animals treated with ETOH extract of EH (EEEH) & standard drug silymarin, all the parameters were normal, possibly due to their beneficial property in protecting the liver against ethanol-induced hepatotoxicity.

   • Selon Vani M (2017)

     Extrait The present investigation has been carried out to evaluate the in vitro & in vivo antihistaminic & anticholinergic activities for the stem extracts of Euphorbia heterophylla, Preliminary phytochemical screening have been carried out on the hydroalcoholic & acetone extracts of the plant. Therefore, stem extracts of EH can be used as antihistaminic & anticholinergic agents which suggest their usage for various therapeutic ailments such as asthma, liver damage, inflammation, & ulcer etc.

   • Selon Okolie NP (2015)

     Extrait ALT did not follow a definite pattern, initially significantly decreasing in plasma & then increasing at the higher extract dose, while the activity of the enzyme significantly increased dose-dependently in the liver (P < 0.05). Although the use of Euphorbia heterophylla as herbal laxative in Nigeria is associated with severe & sometimes life-threatening side effects, not much is known about the toxic effect of the herb.

2. 2

   Infection bacterienne : Klebsiella pneumonia, Staphylococcus aureus, Escherichia coli & Pseudomonas aeruginosa

   Partie usitée : Feuille. Profil pharmacologique documenté : Ceftriaxone-like, Ciprofloxacine-like, Gentamicine-like, Lincocine-like, Ofloxacine-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Adedoyin BJ (2013)

     Extrait Antimicrobial activity tests carried out against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Streptococcus pneumonia & Candida albicans, revealed moderate to low activity against the test organisms. Essential oils were extracted from Euphorbia heterophylla plant (Spurge Weed) using the hydro distillation Clevenger method.

   • Selon Ughachukwu PO (2014)

     Extrait Materials & methods: Clinical isolates of Klebsiella pneumonia, Staphyllococcus aureus, Escherichia coli, & Pseudomonas aeruginosa were incubated in agar plates after serial dilutions (100, 50, 25, 12.5, 6.25, & 3.16 mg/ml) of the extract were added in wells made in the agar & incubated at 37°C. This work evaluated the antibacterial actions of aqueous ethanol leaf extract of Euphorbia heterophylla.

   • Selon Kone JK (2021)

     Extrait The microorganisms tested were nine clinical bacterial strains which included Pseudomonas aeruginosa, Pseudomonas aeruginosa NCIB 950, Salmonella typhi, Escherichia coli, Escherichia coli NCIB 86, Staphylococcus aureus, Staphylococcus aureus NCIB 8588, Klebsiella pneumoniae & Serratia marcescens, & seven fungal strains which were Candida albicans, Aspergillus fumigatus, Aspergillus flavus, Aspergillus parasiticus, Trichoderma viride, Trichophyton rubrum, & Malassezia furfur. Pseudomonas aeruginosa, Pseudomonas aeruginosa NCIB 950 & Candida albicans were sensitive to the cold water a hot water extracts of the plant's parts while chloroform & methanol extracts did not show antimicrobial activities against any of the organisms.

   • Selon Ughachukwu PO (2014)

     Extrait Materials & methods: Clinical isolates of Klebsiella pneumonia, Staphylococcus aureus, Escherichia coli, & Pseudomonas aeruginosa were incubated in agar plates after serial dilutions (100, 50, 25, 12.5, 6.25, & 3.16 mg/ml) of the extract were added in wells made in the agar & incubated at 37°C. This work evaluated the antibacterial actions of aqueous ethanol leaf extract of Euphorbia heterophylla.

   • Selon Auteur (2014)

     Extrait Antibacterial analysis was carried out using agar well diffusion assay against eight pathogenic strains of gram-positive, gram-negative bacteria (Neisseria gonorrhea, Salmonella typhi, Pseudomonas aureginosa, Proteus vulgaris, Staphylococcus aureus, Escherichia coli, Streptococcus pneumonia & Bacillus subtilis) & four different fungal species (Aspergillusniger, Aspergillus tamari, Candida albicans & Fusarium oxysporium). Phytochemical studies revealed the presence of tannins, anthraquinones, alkaloids, flavonoids & phenols in hexane, acetone & water extracts containing only phenol.The plant extracts demonstrated antimicrobial activity against both the test bacteria & fungi with water extract demonstrating the highest activity followed by the acetone extract.

3. 3

   Cancer : traitement adjuvant du carcinome d’ascite

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sundaram MM (2010)

     Extrait Alcoholic extract of plant material showed significant in-vitro cytotoxic activity on EAC (Ehrlich ascites carcinoma) cell lines. Euphorbia heterophylla is a local medicinal plant used in ethno medicine for the treatment of constipation, bronchitis & asthma.

   • Selon Falodun A (2012)

     Extrait The anti-proliferative & apoptotic effects of the methanol extract on human breast cancer cell line (MCF-7) were also investigated by flow cytometry. Euphorbia heterophylla Linn (Euphorbiaceae) is a medicinal plant used in ethnomedicine for the treatment of constipation, bronchitis & asthma.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.