Allium sativum (Lay) : propiedades medicinales en extracción alcohólica

Allium sativum (Lay, Ajo, Ail, Garlic) — familia Liliacées.

Sinónimos científicos : Allium pekinense-Prokhanov, porrum sativum-(l)-Roxb.

Fuentes externas reconocidas asociadas a esta monografía: TRAMIL y Farmacopea francesa.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 28 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 115 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Úlcera diabética

   Parte usada: bulbo.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Semuyaha I (2017)

     Extrait Hyperglycemia was induced by a single intraperitoneal injection of streptozotocin 60 mg/kg followed by 120 mg/kg nicotinamide while extraction of garlic was done by cold maceration method. Group (A), normal control rats, & Group (B), diabetic rats, received 1 ml of normal saline; diabetic rats in Group (C) received 1000 mg/kg of garlic extract orally for 21 days.

   • Selon Ibegbulem CO (2013)

     Extrait The ethanolic extracts of Gongronema latifolium, Aloe perryi, Viscum album (leaves) & Allium sativum (bulb) were investigated for their phytochemical/biochemical constituents & hypoglycemic properties. Materials & Methods: Hypoglycemia was induced in rats by a single dose (140 mg/kg) of intra-péritonéal injection of alloxan monohydrate in citrate buffer (pH 4.5).

   • Selon Kesavanarayanan KS (2013)

     Extrait Anti-diabetic activity of DIA-2 was investigated in high fat diet/low dose streptozotocin induced type II diabetes at four dose levels (62.5, 125, 250 & 500 mg/kg b.w) in rats. The dried bulbs of Allium sativum (Garlic) & leaves of Lagerstroemia speciosa (Banaba) are used as medicinal food for the treatment of diabetes & other ailments.

   • Selon Shakya VK (2010)

     Extrait The Hypoglycemic properties of the ethanolic extract of the bulbs of A sativum were evaluated in normoglycemic rats in order to scientific validate its traditional therapeutic use with the doses of 500 mg/kg body weight. sativum bulbs at dosed equivalent to 100, 250 & 500 mg/kg body weight produced significant (P<0.10) Hypoglycemic effects in normal fasted animals after 7 days & 14 days respectively.

   • Selon Mamun MA (2017)

     Extrait The findings of this study suggest that ethanol extract of garlic grown in Bangladesh possesses the capability of managing hyperglycemia & complications of diabetes in streptozotocin-induced diabetic mice. The present study was conducted to evaluate the hypoglycemic & hypolipidemic effects of ethanol extract of Allium sativum (EEAS) locally grown in Bangladesh.

2. 2

   Diabetes mellitus tipo II

   Parte usada: bulbo.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Semuyaha I (2017)

     Extrait Hyperglycemia was induced by a single intraperitoneal injection of streptozotocin 60 mg/kg followed by 120 mg/kg nicotinamide while extraction of garlic was done by cold maceration method. Group (A), normal control rats, & Group (B), diabetic rats, received 1 ml of normal saline; diabetic rats in Group (C) received 1000 mg/kg of garlic extract orally for 21 days.

   • Selon Ibegbulem CO (2013)

     Extrait The ethanolic extracts of Gongronema latifolium, Aloe perryi, Viscum album (leaves) & Allium sativum (bulb) were investigated for their phytochemical/biochemical constituents & hypoglycemic properties. Materials & Methods: Hypoglycemia was induced in rats by a single dose (140 mg/kg) of intra-péritonéal injection of alloxan monohydrate in citrate buffer (pH 4.5).

   • Selon Kesavanarayanan KS (2013)

     Extrait Anti-diabetic activity of DIA-2 was investigated in high fat diet/low dose streptozotocin induced type II diabetes at four dose levels (62.5, 125, 250 & 500 mg/kg b.w) in rats. The dried bulbs of Allium sativum (Garlic) & leaves of Lagerstroemia speciosa (Banaba) are used as medicinal food for the treatment of diabetes & other ailments.

   • Selon Shakya VK (2010)

     Extrait The Hypoglycemic properties of the ethanolic extract of the bulbs of A sativum were evaluated in normoglycemic rats in order to scientific validate its traditional therapeutic use with the doses of 500 mg/kg body weight. sativum bulbs at dosed equivalent to 100, 250 & 500 mg/kg body weight produced significant (P<0.10) Hypoglycemic effects in normal fasted animals after 7 days & 14 days respectively.

   • Selon Mamun MA (2017)

     Extrait The findings of this study suggest that ethanol extract of garlic grown in Bangladesh possesses the capability of managing hyperglycemia & complications of diabetes in streptozotocin-induced diabetic mice. The present study was conducted to evaluate the hypoglycemic & hypolipidemic effects of ethanol extract of Allium sativum (EEAS) locally grown in Bangladesh.

3. 3

   Infección del tomate: Ralstonia solanacearum

   Parte usada: Acción parasiticida y veterinaria.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Bar M (2022)

     Excerpt Garlic (Allium sativum L.) is widely used in the human diet & in scientific research due to its biological properties.

   • Excerpt According to the literature, extracts obtained using water as a solvent are mainly responsible for antimicrobial properties, which is related to, inter alia, the high content of allicin.

   • Selon El-Khamissi H (2019)

     Excerpt The objective of this study is to determine the phytochemicals of garlic, antioxidants & anticancer activities against cancer cell line (MCF-7) of hot water, cold water & ethanol extracts of garlic (Allium Sativum). Finally, garlic extracts also showed very high cytotoxic activity against human breast cancer cell line type (MCF-7) especially ethanol extract, which makes us recommend that garlic is useful as a rich antioxidant & has great strength against cancer cells,.

   • Selon PRABHU et al (s.d.)

     Excerpt Objectives: To assess the anticancer effect of Allium sativum & Foeniculum vulgare extracts, as a combination extract, on oral squamous cell carcinoma cell lines (KB & Cal 27 cell lines). The survival index of Oral squamous cell carcinoma/ Oral cancer/ OSCC has remained static over the past few decades.

   • Selon Prakash Ekta (2016)

     Excerpt The objective of the study was to determine the anticancer properties of ethanolic extract of AS against human cancer cell lines. Allium Sativum is a perennial plant with narrow flat leaves & several small bulbs, known as clove, enclosed in a white skin.

   • Selon Karasaki Y (2001)

     Excerpt Cytotoxic effects of a lectin prepared from garlic (Allium sativum-L) bulbs on human tumor cells were studied. The antitumor activity of garlic lectin may provide a rational basis for its effectiveness observed in clinical applications.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.