Allium sativum (Lay) : vertus médicinales en extraction alcoolique

Allium sativum (Lay, Ail, Garlic) — famille Liliacées.

Synonymes scientifiques : Allium pekinense-Prokhanov, porrum sativum-(l)-Roxb.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 25 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 102 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Plaie diabétique

   Partie usitée : Bulbe.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Semuyaha I (2017)

     Extrait Hyperglycemia was induced by a single intraperitoneal injection of streptozotocin 60 mg/kg followed by 120 mg/kg nicotinamide while extraction of garlic was done by cold maceration method. Group (A), normal control rats, & Group (B), diabetic rats, received 1 ml of normal saline; diabetic rats in Group (C) received 1000 mg/kg of garlic extract orally for 21 days.

   • Selon Ibegbulem CO (2013)

     Extrait The ethanolic extracts of Gongronema latifolium, Aloe perryi, Viscum album (leaves) & Allium sativum (bulb) were investigated for their phytochemical/biochemical constituents & hypoglycemic properties. Materials & Methods: Hypoglycemia was induced in rats by a single dose (140 mg/kg) of intra-péritonéal injection of alloxan monohydrate in citrate buffer (pH 4.5).

   • Selon Shakya VK (2010)

     Extrait The Hypoglycemic properties of the ethanolic extract of the bulbs of A sativum were evaluated in normoglycemic rats in order to scientific validate its traditional therapeutic use with the doses of 500 mg/kg body weight. sativum bulbs at dosed equivalent to 100, 250 & 500 mg/kg body weight produced significant (P<0.10) Hypoglycemic effects in normal fasted animals after 7 days & 14 days respectively.

   • Selon Mamun MA (2017)

     Extrait The findings of this study suggest that ethanol extract of garlic grown in Bangladesh possesses the capability of managing hyperglycemia & complications of diabetes in streptozotocin-induced diabetic mice. The present study was conducted to evaluate the hypoglycemic & hypolipidemic effects of ethanol extract of Allium sativum (EEAS) locally grown in Bangladesh.

   • Selon Mejia-Delgado EM (2025)

     Extrait The search included terms such as "allium sativum", "inflammation", "oxidative stress", & "diabetes mellitus". Type 2 diabetes mellitus (T2DM) is a metabolic disorder marked by chronic hyperglycemia and low-grade inflammation, contributing to various complications.

2. 2

   Diabète mellitus de type II

   Partie usitée : Bulbe. Profil pharmacologique documenté : Glibenclamide-like, Glimepiride-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Semuyaha I (2017)

     Extrait Hyperglycemia was induced by a single intraperitoneal injection of streptozotocin 60 mg/kg followed by 120 mg/kg nicotinamide while extraction of garlic was done by cold maceration method. Group (A), normal control rats, & Group (B), diabetic rats, received 1 ml of normal saline; diabetic rats in Group (C) received 1000 mg/kg of garlic extract orally for 21 days.

   • Selon Ibegbulem CO (2013)

     Extrait The ethanolic extracts of Gongronema latifolium, Aloe perryi, Viscum album (leaves) & Allium sativum (bulb) were investigated for their phytochemical/biochemical constituents & hypoglycemic properties. Materials & Methods: Hypoglycemia was induced in rats by a single dose (140 mg/kg) of intra-péritonéal injection of alloxan monohydrate in citrate buffer (pH 4.5).

   • Selon Shakya VK (2010)

     Extrait The Hypoglycemic properties of the ethanolic extract of the bulbs of A sativum were evaluated in normoglycemic rats in order to scientific validate its traditional therapeutic use with the doses of 500 mg/kg body weight. sativum bulbs at dosed equivalent to 100, 250 & 500 mg/kg body weight produced significant (P<0.10) Hypoglycemic effects in normal fasted animals after 7 days & 14 days respectively.

   • Selon Mamun MA (2017)

     Extrait The findings of this study suggest that ethanol extract of garlic grown in Bangladesh possesses the capability of managing hyperglycemia & complications of diabetes in streptozotocin-induced diabetic mice. The present study was conducted to evaluate the hypoglycemic & hypolipidemic effects of ethanol extract of Allium sativum (EEAS) locally grown in Bangladesh.

   • Selon Mejia-Delgado EM (2025)

     Extrait The search included terms such as "allium sativum", "inflammation", "oxidative stress", & "diabetes mellitus". Type 2 diabetes mellitus (T2DM) is a metabolic disorder marked by chronic hyperglycemia and low-grade inflammation, contributing to various complications.

3. 3

   Infection de la tomate : Ralstonia solanacearum

   Partie usitée : Bulbe.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Bar M (2022)

     Excerpt Garlic (Allium sativum L.) is widely used in the human diet & in scientific research due to its biological properties.

   • Excerpt According to the literature, extracts obtained using water as a solvent are mainly responsible for antimicrobial properties, which is related to, inter alia, the high content of allicin.

   • Selon El-Khamissi H (2019)

     Excerpt The objective of this study is to determine the phytochemicals of garlic, antioxidants & anticancer activities against cancer cell line (MCF-7) of hot water, cold water & ethanol extracts of garlic (Allium Sativum). Finally, garlic extracts also showed very high cytotoxic activity against human breast cancer cell line type (MCF-7) especially ethanol extract, which makes us recommend that garlic is useful as a rich antioxidant & has great strength against cancer cells,.

   • Selon Prakash Ekta (2016)

     Excerpt The objective of the study was to determine the anticancer properties of ethanolic extract of AS against human cancer cell lines. Allium Sativum is a perennial plant with narrow flat leaves & several small bulbs, known as clove, enclosed in a white skin.

   • Selon Karasaki Y (2001)

     Excerpt Cytotoxic effects of a lectin prepared from garlic (Allium sativum-L) bulbs on human tumor cells were studied. The antitumor activity of garlic lectin may provide a rational basis for its effectiveness observed in clinical applications.

   • Selon Garcia A (s.d.)

     Excerpt Garcia A et al, A comparative study on the antifungal effects of tamarind (Tamarindus indica) & garlic (Allium sativum) extracts on banana anthracnose.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.