Basella alba (Espinaca de Malabar) : propiedades medicinales en extracción alcohólica

Basella alba (Espinaca de Malabar, Epinard de Malabar, Malabar spinach) — familia Basellacéess.

Sinónimos científicos : Basella cordifolia Lam, B crassifolia Salisb, B japonica Burm.f., B nigra Lour., B ramosa J.Jacq. ex Spreng., B rubra-L.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 13 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 59 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Hepato- y nefrotoxicidad inducida por la acrilamida

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Adewale OO (2022)

     Extrait Basella alba has been reported to have medicinal properties, & in this study, the anti-oxidative potentials of ethanol leaf extract of BA were assessed against oxidative stress induced by acrylamide in male Wistar rats (120-150g). The liver & kidney tissues were processed for the analyses of antioxidant activities.

   • Selon Olubayode B (2015)

     Extrait This work investigated the effect of ethanolic extract of BA on lead- induced hepatotoxicity in male rats. Then, levels of the liver enzymes in the serum were measured.

   • Selon Nirmala A (2009)

     Extrait In liver, the changes caused after induction of diabetes was global microvesicular steatosis .The portal tracts appeared normal & central veins appeared congested, which was brought back to normal after feeding with BR. The diabetes-induced rats were fed with BR(400 mg/100 gm body weight orally through a gavage), when tested after ingestion the fasting blood glucose levels were remarkably reduced to normal & liver glycogen content was remarkably increased.

   • Selon Yanadaiah JP (2011)

     Extrait The aqueous ethanolic extract of aerial parts of BR has shown very significant hepatoprotection against both Paracetamol induced and CCl4-induced hepatotoxicity study models in wistar rats. The present study was conducted to evaluate the hepatoprotective activity of aqueous ethanolic extract of aerial parts of BR in wistar rats.

   • Selon Kumar BR (2018)

     Extrait The evaluation of the cytoxicity of these extracts on A431 (epidermoid carcinoma), Hep G2 (hepatocellular carcinoma) & MG 63 (osteosarcoma) cells indicated anti-proliferative activity against all the cell lines. These studies indicate that Basella sps can be used as a source of natural antioxidants & can be of high significance in pharmaceutical & nutraceutical industries.

2. 2

   Cirrosis hepática, esteatosis hepática

   Parte usada: partes aéreas.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Adewale OO (2022)

     Extrait Basella alba has been reported to have medicinal properties, & in this study, the anti-oxidative potentials of ethanol leaf extract of BA were assessed against oxidative stress induced by acrylamide in male Wistar rats (120-150g). The liver & kidney tissues were processed for the analyses of antioxidant activities.

   • Selon Yanadaiah JP (2011)

     Extrait The aqueous ethanolic extract of aerial parts of BR has shown very significant hepatoprotection against both Paracetamol induced and CCl4-induced hepatotoxicity study models in wistar rats. The present study was conducted to evaluate the hepatoprotective activity of aqueous ethanolic extract of aerial parts of BR in wistar rats.

   • Selon Olubayode B (2015)

     Extrait This work investigated the effect of ethanolic extract of BA on lead- induced hepatotoxicity in male rats. Then, levels of the liver enzymes in the serum were measured.

   • Selon Kumar BR (2018)

     Extrait The evaluation of the cytoxicity of these extracts on A431 (epidermoid carcinoma), Hep G2 (hepatocellular carcinoma) & MG 63 (osteosarcoma) cells indicated anti-proliferative activity against all the cell lines. These studies indicate that Basella sps can be used as a source of natural antioxidants & can be of high significance in pharmaceutical & nutraceutical industries.

   • Selon Nirmala A (2009)

     Extrait In liver, the changes caused after induction of diabetes was global microvesicular steatosis .The portal tracts appeared normal & central veins appeared congested, which was brought back to normal after feeding with BR. The diabetes-induced rats were fed with BR(400 mg/100 gm body weight orally through a gavage), when tested after ingestion the fasting blood glucose levels were remarkably reduced to normal & liver glycogen content was remarkably increased.

3. 3

   Hipertensión arterial, retención de líquidos, edema

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kumar V (2011)

     Extrait In this work the methanolic extract of Basella alba (M.E.B.A.) & aqueous extract of BA were studied for its in-vitro antiinflammatory activities. The aqueous extract showed the most significant membrane stabilizing action on human red blood cell membrane.

   • Selon Auteur (2012)

     Extrait Basella alba is used in many parts of the world for its medicinal use as laxative, anti-inflammatory, rubefacient, soothing as well as its cooling effects when applied to burns & scalds.

   • Selon Deshmukh SK (2014)

     Extrait Major biological activities exhibited by BA is androgenic, antidiabetic, anti-inflammatory, antimicrobial, antioxidant, antiulcer, antiviral, CNS depressant, hepatoprotective & wound healing, properties.

   • Selon RODDA R (2012)

     Extrait RODDA R et al, INVESTIGATION ON ANTI INFLAMMATORY PROPERTY OF BASELLA ALBA LINN LEAF EXTRACT, Inter J of Pharm & Pharmaceul Sci, 4, :1, 2012,.

   • Selon Ashraduzzaman Nur (2023)

     Extrait alba (native & hybrid) fruit extract & measurement its biological activities like antioxidant, anti-inflammatory, cytotoxic activities & a molecular docking were performed to observed the pharmaceutical impact on the anti-inflammatory Cyclooxygenase-2 (COX-2) enzyme. In anti-inflammatory activity assessment study, the IC50 values of the ethanol extracts were 20.52 ± 0.91 μg/mL for BSA inhibition a 20.43 ± 1.30 μg/mL for RBC hemolytic inhibitory study.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.