Cnidoscolus chayamansa (Lachaya) : propiedades medicinales en extracción alcohólica
Cnidoscolus chayamansa (Lachaya) — familia Euphorbiacées.
Sinónimos científicos : C. aconitifolius-(Mill)-Johnston.
Fuentes externas reconocidas asociadas a esta monografía: TRAMIL.
Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 13 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 46 referencias científicas para esta especie (detalle completo en la aplicación).
Indicaciones terapéuticas en extracción alcohólica:
Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).
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Diabetes mellitus tipo II
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Echeverria-Bobadilla F (2014)
Extrait Cnidoscolus chayamansa, is an endemic plant from the Southeastern of Mexico known for its easy & cheap growing requirements. chayamansa contains dihydro-myricetin a flavonoid that is believed exerts Hypoglycemic effects.
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Selon Oyagbemi AA (2010)
Extrait This research was designed to investigate the antidiabetic properties of ethanolic extract of Cnidoscolus aconitifolius in alloxan-induced diabetes mellitus in Wistar male albino rats. From this study, CA extract was found to considerably reduce blood glucose & plasma cholesterol levels & progressively increase weight gain in diabetic treated rats confirming its traditional use for the treatment of diabetes.
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Selon García-Rodríguez RV (2014)
Extrait CC is also used as a traditional remedy for the treatment of diabetes, rheumatism, gastrointestinal disorders a& inflammation-related diseases. C chayamansa Mc V (Euphorbiaceae) is commonly known as 'Chaya' in Central America.
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Selon IWUJI SC (2014)
Extrait This study investigated the blood glucose lowering efficacy of the chloroform fraction of hydromethanolic leaf extract of Cnidoscolus aconitifolius (CA) compared with Glibenclamide in alloxan-induced diabetic Wistar rats. Effective dose of CA could prevent the rapid hypoglycaemic side effect in glibenclamide usage.
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Selon Roy DN (2016)
Extrait This study is aimed at investigating the phytocomponents & hypoglycemic effect of ethanolic leaf extract of CA in streptozotocin induced-diabetic mice. Hypoglycemic effect was investigated in streptozotocin-induced diabetic mice and a dose dependent reduction in blood glucose level was found to have with huge reduction at a dose of 200 mg/kg from 245.33±13.01 (mg/dl) to 187.03±7.19 (mg/dl) after intraperitoneal administration (p<0.05) of extract.
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Selon Echeverria-Bobadilla F (2014)
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Hepatitis, esteatosis hepática, cirrosis
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Pillai KK (2012)
Extrait Administration of ethanolic extracts of Cnidoscolus chayamansa significantly prevented Rifampicin-Isoniazid-induced elevation in the levels of serum diagnostic liver marker enzymes aspartate amino transferase (AST), alanine amino transferase (ALT) & alkaline phosphatase (ALP) level in experimental groups of rats. The effect of ethanolic extract of Cnidoscolus chayamansa (Family of Euphorbiaceae) leaves in experimentally drug induced hepatitis in rats.
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Selon Quintal-Martinez JP (2021)
Extrait In Mexico, Cnidoscolus aconitifolius (Chaya) has been used to treat cardiovascular diseases (CVD).
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Selon Pillai K (2012)
Extrait The normalization of these effects observed in the serum treated with EECC possesses significant antitumor & hepatoprotective effect of the extracts. Plants of Chayamansa were traditionally used in the treatment of tumors.
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Selon Manzanilla-Valdès ML (2021)
Extrait Aqueous, ethanolic, methanolic, & ethyl acetate extracts of Cnidoscolus aconitifolius have shown nephroprotective & hepatoprotective potential & can be an alternative to prevent & treat CKD & LD. Chaya extracts are no toxic for renal & hepatic cells,.
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Selon Pillai KK (2012)
Extrait in India the decoction of Chaya (Cnidoscolus chayamansa) is used as a house hold remedies for diabetics. The alteration in hepatic glycogen content & hepatic glucokinase, hexokinase a&glucose-6-phosphate levels in diabetic rats were partially restored by Ethanolic extracts of CC.
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Selon Pillai KK (2012)
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Cáncer: tratamiento adyuvante del carcinoma de ascitis
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Pillai K (2012)
Extrait The present investigation was carried out to evaluate the antitumor activity of Ethanolic extracts of CC in DLA tumor bearing mice. The EECC treated animals at the doses of 200 & 400 mg/kg significantly inhibited the tumor volume, packed cell volume, tumor (viable) cell count and brought back the hematological parameters to more or less normal levels.
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Selon Pillai K (2012)
Extrait Ethanolic Extract of Cnidoscolus chayamansa (EECC) has been used in traditional & folklore medicine for the treatment of cancer. The aim of the present study was to evaluate the effect of Ethanolic Extract of leaves of C chayamansa (EECC) against intraperitoneally injected Dalton's Ascitic Lymphoma (DAL) cell lines in Swiss albino mice.
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Selon Pillai K (2014)
Extrait The present study was performed experimentally by Invitro method to examine the anti-cancer activity at various concentration (62.5μg/ml - 1000 μg/ml) of ethanolic extract of the leaves of Cnidoscolus chayamansa against HT-29 (Colon Carcinoma) cell lines using MTT assay method. The anticancer properties of Cnidoscolus chayamansa will provide useful information in the possible application in the treatment of neoplastic therapy & prevention.
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Selon Periyar Maniammai (s.d.)
Extrait Chayamansa at high dose & low dose exhibited significant anti-hyperglemic activity in normal & alloxan-diabetic rats.
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Selon Pillai K (2012)
Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.
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+2 referencias · ~6 referencias corregidas · −3 referencias
Solo contadores y dominios: los nombres de indicaciones y sinergias no se listan aquí (abrir la ficha en la aplicación). Los textos de las referencias añadidas, corregidas o retiradas están abajo.
+2 referencias — mostrar textos
Calonico K et al, Digestion-Related Enzyme Inhibition Potential of Selected Mexican Medicinal Plants (Ludwigia octovalvis (Jacq.) P.H. Raven, Cnidoscolus aconitifolius & Crotalaria longirostrata) Foods.12:3529. 2023-Abstract: Medicinal plants offer a valuable source of natural compounds with specific & selective bioactivity. These compounds have been isolated since the mid-nineteenth century & are now commonly used in modern medications. L. octovalvis (Jacq.) P.H. Raven, C. aconitifolius, & C. longirostrata are Mexican medicinal plants consumed regularly, & research has shown that they cont…
AñadidaCALONICO K et al, Technological Performance & Nutritional Modulation of Bread Enriched with Cnidoscolus aconitifolius & Crotalaria longirostrata Leaf Flours, Plants (Basel), 15(1):71. 2025-Abstract: Bread typically exhibits a high glycemic index (GI), motivating interest in plant-based ingredients that can modulate starch digestibility while enhancing nutritional value. This study evaluated the technological, compositional, & digestibility effects of incorporating leaf flours from Cnidoscolus aconitifolius & Crotalaria longirostrata into wheat bread. Both flours increased protein, dietary f…
AñadidaPROGRESS IN NEW CROPS: POTENTIAL NUTRITIONAL & HEALTH BENEFITS - OF TREE SPINACH, ASH Press: http://www.hort.purdue.edu/newcrop/proceedings1996/V3-516.html. Comparisons of Nutritional compositions of leaves of "Chaya" (Cnidoscolus chayamansa McVaugh) & spinach (Spinacia oleracea L.) per 100 g fresh weight.
CorregidaPHYTOCHEMICAL CONSTITUENTS, ANTIMICROBAL & ANTIOXIDANT POTENTIALS OF TREE SPINACH, Jl of Med Plants Res, 7(19) :1317-122,
CorregidaStudies in Cnidoscolus (Euphorbiaceae). Brittonia 31 :1979, 125-48.
CorregidaChaya, Cnidoscolus Chayamansa Includes Composition & Nutritional Value, Culture in Puerto Rico, In: Vegetables of Hot Humid Tropics, USDA, ARS. LA. (1978).
CorregidaChaya (Cnidoscolus chayamansa, Euphorbiaceae), a marvelous food (in spanish). Tierra 30 :1975, 407-408, 427-8.
CorregidaRoy DN et al, Phytochemical screening, nutritional profile and anti-diabetic effect of ethanolic leaf extract of Cnidoscolus aconitifolius in streptozotocin induce diabetic mice. Inter Jl B Chem Pharm, 5(5): 2244-50.2016-Abstract: Cnidoscolus aconitifolius is a perennial shrub of the family: Euphorbiaceae commonly found in the tropics. This study is aimed at investigating the phytocomponents & hypoglycemic effect of ethanolic leaf extract of CA in streptozotocin induced-diabetic mice. Methods: Thirty (30) mice with average weight of 23g were randomly assigned into five groups of 6 each anim…
CorregidaComparisons of Nutritional compositions of leaves of "Chaya" (Cnidoscolus chayamansa McVaugh) & spinach (Spinacia oleracea L.) per 100 g fresh weight.
RetiradaUs-Medina U et al. In Vitro Antioxidant & Anti-Inflammatory Activity of Chaya Extracts (Cnidoscolus aconitifolius (Mill.) I.M. Johnst)]. Nutr. Hosp. 37, 46–55. 2020-Abstract: Secondary metabolites from plant sources such as Cnidoscolus aconitifolius may be used as adjuvants in the prevention of diseases related to oxidative stress & inflammation such as NCDs. Objective: the in vitro antioxidant & anti-inflammatory activities associated with biologically active compounds in CA extracts were evaluated. Method: the contents of phenols, flavonoids, flavonones & hydroflavonols were determined. T…
RetiradaManzanilla Valdez MZ et al, Antidiabetic & Hypotensive Effect of Cnidoscolus aconitifolius (Mill) I.M Johnst Leaves Extracts. Jl. Food Meas. Charact. 15, 5245–5255. 2021-Abstract : The aim of this study was to evaluate hypotensive & hypoglycemic effect of six Chaya leaves extracts (aqueous, ethanolic, acetone, ethyl acetate, diethyl ether & hexane). The leaves of Cnidoscolus aconitifolius (Mill) IM Johnst were collected in Timucuy, Yucatan, Mexico. Maceration for 48 h was the technique selected for the extraction process, with a proportion of 1: 10 (w/v) & the following solvents: distil…
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