Cnidoscolus chayamansa (Lachaya) : vertus médicinales en extraction alcoolique

Cnidoscolus chayamansa (Lachaya) — famille Euphorbiacées.

Synonymes scientifiques : C. aconitifolius-(Mill)-Johnston.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 47 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Chlorpropamide-like, Metformine-like, Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Echeverria-Bobadilla F (2014)

     Extrait Cnidoscolus chayamansa, is an endemic plant from the Southeastern of Mexico known for its easy & cheap growing requirements. chayamansa contains dihydro-myricetin a flavonoid that is believed exerts Hypoglycemic effects.

   • Selon Manzanilla Valdez MZ (2021)

     Extrait Hypotensive effect, glucose tolerance curve & hypoglycaemic effect was evaluated in rats induced to obesity, hyperglycemia & hypertension. The aim of this study was to evaluate hypotensive & hypoglycemic effect of six Chaya leaves extracts (aqueous, ethanolic, acetone, ethyl acetate, diethyl ether & hexane).

   • Selon Oyagbemi AA (2010)

     Extrait This research was designed to investigate the antidiabetic properties of ethanolic extract of Cnidoscolus aconitifolius in alloxan-induced diabetes mellitus in Wistar male albino rats. From this study, CA extract was found to considerably reduce blood glucose & plasma cholesterol levels & progressively increase weight gain in diabetic treated rats confirming its traditional use for the treatment of diabetes.

   • Selon García-Rodríguez RV (2014)

     Extrait CC is also used as a traditional remedy for the treatment of diabetes, rheumatism, gastrointestinal disorders a& inflammation-related diseases. C chayamansa Mc V (Euphorbiaceae) is commonly known as 'Chaya' in Central America.

   • Selon IWUJI SC (2014)

     Extrait This study investigated the blood glucose lowering efficacy of the chloroform fraction of hydromethanolic leaf extract of Cnidoscolus aconitifolius (CA) compared with Glibenclamide in alloxan-induced diabetic Wistar rats. Effective dose of CA could prevent the rapid hypoglycaemic side effect in glibenclamide usage.

2. 2

   Hépatite, stéatose hépatique, cirrhose

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pillai KK (2012)

     Extrait Administration of ethanolic extracts of Cnidoscolus chayamansa significantly prevented Rifampicin-Isoniazid-induced elevation in the levels of serum diagnostic liver marker enzymes aspartate amino transferase (AST), alanine amino transferase (ALT) & alkaline phosphatase (ALP) level in experimental groups of rats. The effect of ethanolic extract of Cnidoscolus chayamansa (Family of Euphorbiaceae) leaves in experimentally drug induced hepatitis in rats.

   • Selon Quintal-Martinez JP (2021)

     Extrait In Mexico, Cnidoscolus aconitifolius (Chaya) has been used to treat cardiovascular diseases (CVD).

   • Selon Pillai K (2012)

     Extrait The normalization of these effects observed in the serum treated with EECC possesses significant antitumor & hepatoprotective effect of the extracts. Plants of Chayamansa were traditionally used in the treatment of tumors.

   • Selon Manzanilla-Valdès ML (2021)

     Extrait Aqueous, ethanolic, methanolic, & ethyl acetate extracts of Cnidoscolus aconitifolius have shown nephroprotective & hepatoprotective potential & can be an alternative to prevent & treat CKD & LD. Chaya extracts are no toxic for renal & hepatic cells,.

   • Selon Pillai KK (2012)

     Extrait in India the decoction of Chaya (Cnidoscolus chayamansa) is used as a house hold remedies for diabetics. The alteration in hepatic glycogen content & hepatic glucokinase, hexokinase a&glucose-6-phosphate levels in diabetic rats were partially restored by Ethanolic extracts of CC.

3. 3

   Arthrite, arthrose, rhumatisme

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon García-Rodríguez RV (2014)

     Extrait When tested for their antioxidant activity none of the extracts showed a significant activity suggesting that the anti-inflammatory activity is not related to a direct free radical scavenging of the extracts. RESULTS: The results showed a similar anti-inflammatory activity (≈30%) for all extracts but only the EtOAc extract showed relevant activity when applied intraperitoneally.

   • Selon Onasanwo SA (2011)

     Extrait METHODS: The analgesic activity of the extract was assayed by the formalin-induced paw licking test, acetic acid-induced abdominal writhing & hot plate test, whereas its anti-inflammatory activity was determined by its effects on carrageenan-induced paw edema. Ethanolic leaf extract of Cnidoscolus aconitifolius was evaluated for analgesic & anti-inflammatory activities.

   • Selon Perez-Gonzalez MZ (2018)

     Extrait chayamansa leaves & pure compounds (moretenol, moretenyl acetate, kaempferol-3,7-dimethyl ether, and 5-hydroxy-7-3',4'-trimethoxyflavanone) showed important topical and systemic anti-inflammatory activity in acute model, as well as in vitro antimycobacterial & antiprotozoal activities. In this paper, we describe the in vivo hepatoprotective & anti-inflammatory effects of the CHCl3: MeOH extract in chronic model and the isolation of additional compounds (moretenone & lupeol acetate).

   • Selon Mena Y (2015)

     Extrait Traditionally, it is used for diabetes, obesity, arthritis & anti-inflammatory in several disturbances associated to inflammatory processes. The specie Cnidoscolus chayamansa is an important nutritive source because of its high percent of proteins & minerals.

   • Selon Us-Medina U (2020)

     Extrait The ETOH extract had the highest anti-inflammatory activity, decreasing gene expression for TNF- by 39.78% & for IL-6 by 97.81%, & their production by 46% & 48.38%, respectively, in macrophages stimulated with LPS. Secondary metabolites from plant sources such as Cnidoscolus aconitifolius may be used as adjuvants in the prevention of diseases related to oxidative stress & inflammation such as NCDs.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.