Euphorbia neriifolia (Elaikalli) : propiedades medicinales en extracción alcohólica

Euphorbia neriifolia (Elaikalli) — familia Euphorbiacées.

Sinónimos científicos : Elaophorbia neriifolia-(L)-A.Chev, Euphorbia edulis-L, E. ligularis-Roxb., Tithymalus edulis-(L)-HK.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 20 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 50 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Cáncer: tratamiento adyuvante del carcinoma hepático y renal; quimioprevención del carcinoma hepático y renal

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pracheta (s.d.)

     Extrait This idea has prompted to evaluate the hepatoprotective properties of hydroethanolic extract of Euphorbia neriifolia (EN) Linn against N-Nitrosodiethylamine (DENA) induced liver cancer in mice. This study rationalized the ethnomedicinal use of the EN for curing liver cancer.

   • Selon SHARMA V (2014)

     Extrait The aim of this study was to examine the impacts of N-Nitrosodiethylamine (DENA), a potent environment carcinogen on liver tissue of mice which was attenuated by isolated flavonoid & hydro-ethanolic extract of E neriifolia (HEEN) leaves. neriifolia lower (ENL) & higher (ENH) dose & ENF before intoxicated with DENA showed that the liver cells were normal, with very little necrosis (Day 31).

   • Selon SHARMA V (2012)

     Extrait To scrutinize the protective role of hydroethanolic extract of E neriifolia leaves (HEEN) against N-Nitrosodiethylamine (DENA)-induced hepatocarcinogenesis in male Swiss albino mice .METHODS: Experimental mice were pretreated with 150 & 400 mg/kg of HEEN, or 0.5% & 1% of butylated hydroxyanisole (BHA) as a standard for 14 d prior to the administration of a single dose of 50 mg/kg of DENA. Levels of xenobiotic metabolizing enzymes such as cytochrome (Cyt) P450 & Cyt b5, activities of reduced glutathione (GSH), glutathione-S-transferase (GST), aspartate amino transaminase (AST), alanine amino transaminase (ALT) & alkaline phosphatase (ALP), & total protein and cholesterol content in the liver tissues were measured to determine the hepatotoxicity caused by DENA.

   • Selon Pracheta (2011)

     Extrait The present study was conducted to investigate the chemopreventive effects of hydroethanolic extract of Euphorbia neriifolia (EN) on N-Nitrosodiethylamine (DENA) induced renal cancer in male Swiss albino mice. This study rationalized the ethnomedicinal use of EN for protection against renal cancer.

   • Selon SHARMA V (2013)

     Extrait This study is an attempt to evaluate the tissue protective efficacy of isolated flavonoid & hydroethanolic extract of Euphorbia neriifolia (HEEN) leaves against N-Nitrosodiethylamine (DENA) induced renal carcinoma. On the other hand, the mice treated with E neriifolia lower (ENL) & higher (ENH) dose & ENF before intoxicated with DENA showed that the renal cells were normal (Day 31).

2. 2

   Diabetes mellitus tipo II

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon MANSURI MI (2013)

     Extrait MANSURI MI et al, Evaluation of Antidiabetic and Antihyperlipidemic Activity of Euphorbia Neriifolia L in High Fat Diet- Streptozotocin Induced Type-2 Diabetic Model, Int Jl for Pharmaceut Res Scholars, 2(1-1) :83-9, 2013-Abstract Euphorbia neriifolia is traditionally used to treat diabetes mellitus. The purpose of this study was to examine the effect of repeated oral administration of the ethanolic extract of E neriifolia Linn at a dose of (200 and 400 mg/kg) on fasting blood glucose levels and lipid metabolism in streptozotocin induced type-2 diabetic rats.

   • Selon Mansuri MI (2012)

     Extrait Purpose of the study was to evaluate the antidiabetic activity of ethanolic extracts of leaves of E neriifolia in alloxan induced diabetic rats. The extract of Euphorbia neriifolia Linn are having potential in the development of drug for diabetes due to their antidiabetic activity.

   • Selon Devi S (2023)

     Extrait The scavenging activity of 2,2-diphenyl-2-picrylhydrazyl & hydrogen peroxide was used to study the antioxidant activity of hydroalcoholic extract of HAE) Plasma glucose content, lipid profiles, insulin levels, GLUT-4 protein content in muscle homogenates, inhibition of amylase & pancreatic glucosidase, & pancreatic histology were measured in control & diabetic rats. In the present study, the extract from the stem of Euphorbia neriifolia was used to investigate its antioxidant & antidiabetic activity.

   • Selon Bigoniya P (2006)

     Extrait neriifolia saponin fraction can be usefulness in the treatment of disorders that involve oxidative stress like cancer, cardiovascular diseases, diabetes & inflammation. Crude saponin was separated from hydroalcoholic extract of Euphorbia neriifolia leaf which contains Euphol as a major sapogenin.

   • Selon Bigoniya P (2009)

     Extrait neriifolia extract treatment extreme significantly (p < 0.001) reduced serum lipid profile along with glucose establishing its catabolic property. neriifolia leaf extract on some haematological, biochemical, histological & antioxidant enzyme status of rat liver & kidney following 21- & 45-days treatment.

3. 3

   Hepatitis, cirrosis, esteatosis hepática

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pracheta (s.d.)

     Extrait This idea has prompted to evaluate the hepatoprotective properties of hydroethanolic extract of Euphorbia neriifolia (EN) Linn against N-Nitrosodiethylamine (DENA) induced liver cancer in mice. The EN extract significantly restored the antioxidant enzyme level in the liver and exhibited significant dose dependant protective effect against DENA induced liver toxicity, which can be mainly attributed to the antioxidant property of the extract.

   • Selon SHARMA V (2014)

     Extrait The aim of this study was to examine the impacts of N-Nitrosodiethylamine (DENA), a potent environment carcinogen on liver tissue of mice which was attenuated by isolated flavonoid & hydro-ethanolic extract of E neriifolia (HEEN) leaves. neriifolia lower (ENL) & higher (ENH) dose & ENF before intoxicated with DENA showed that the liver cells were normal, with very little necrosis (Day 31).

   • Selon SHARMA V (2012)

     Extrait To scrutinize the protective role of hydroethanolic extract of E neriifolia leaves (HEEN) against N-Nitrosodiethylamine (DENA)-induced hepatocarcinogenesis in male Swiss albino mice .METHODS: Experimental mice were pretreated with 150 & 400 mg/kg of HEEN, or 0.5% & 1% of butylated hydroxyanisole (BHA) as a standard for 14 d prior to the administration of a single dose of 50 mg/kg of DENA. Levels of xenobiotic metabolizing enzymes such as cytochrome (Cyt) P450 & Cyt b5, activities of reduced glutathione (GSH), glutathione-S-transferase (GST), aspartate amino transaminase (AST), alanine amino transaminase (ALT) & alkaline phosphatase (ALP), & total protein and cholesterol content in the liver tissues were measured to determine the hepatotoxicity caused by DENA.

   • Selon Bigoniya P (2009)

     Extrait neriifolia leaf extract on some haematological, biochemical, histological & antioxidant enzyme status of rat liver & kidney following 21- & 45-days treatment. neriifolia showed an extremely significant (p < 0.001) rise in liver & kidney SOD along with liver catalase and decrease in liver lipid peroxidation.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.