Khaya senegalensis (Caoba de Senegal) : propiedades medicinales en extracción alcohólica

Khaya senegalensis (Caoba de Senegal, Mohagán de Senegal, Caïlcedrat real, Acajou du Sénégal, Mahogani du Sénégal, Caïlcedrat royal, Senegalese mahogany, Royal Caïlcedrat) — familia Méliacées.

Sinónimos científicos : Swietenia senegalensis-Desv.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 10 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 25 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Diabetes mellitus tipo II

   Parte usada: Corteza.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Widdat Allah MO (2019)

     Extrait Khaya senegalensis has traditionally used in the management of diabetes. The leaves & bark of the plant were extracted with ethanol 96%, & then tested for anti-diabetic activity in a series of in vitro models & a type 2 diabetes model of rats.

2. 2

   Cáncer: quimioprevención del carcinoma colorrectal

   Parte usada: Corteza.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Andreoulakis XM (2006)

     Extrait Khaya senegalensis bark extract (KSBE) was hypothesized to contain inhibitors of the cyclooxygenase-2 (COX-2) gene & to be useful in the prevention and treatment of colorectal cancer. An extract of the bark of Khaya senegalensis is commonly used in African traditional medicine for pain & inflammation.

   • Selon Zhang H (2007)

     Extrait Two limonoids were isolated from the methanol extract of Khaya senegalensis (Meliaceae), & their structures were identified as 3alpha,7alpha-dideacetylkhivorin (1) & 1-O-acetylkhayanolide B (2) on the basis of MS & NMR spectral data.

   • Selon Rabadeux C (2017)

     Extrait Khaya senegalensis (Desr.) A. This study was undertaken to test KS bark extracts for the ability to inhibit microbial & cancer cell growth, & thus to validate traditional African medicinal usage of this plant in treating a variety of diseases.

   • Selon Olugbami OJ (2017)

     Extrait In this study, therefore, we evaluated the antimetastatic potentials of an extract of Khaya senegalensis & curcumin on the metastatic liver cell line HepG2, & also assessed the anticancer property of the extract. Treated cells were assessed as follows: nanotechnologically—atomic force microscopy (AFM) was used to determine cell stiffness; biochemically—cell cytotoxicity, glutathione level & adenosine triphosphate status, caspase activation & mitochondrial toxicity were considered; & microbiologically—a carrot disk assay was used to assess the anticancer property of the extract of KS.

3. 3

   Infección bacteriana: Escherichia coli, Salmonella typhii, Staphylococcus aureus, Klebsiella pneumoniae, Streptococcus faecalis, Shigella sp.

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Wakirwa JH (2010)

     Extrait Khaya senegalensis ethanol leaf extract was examined for antimicrobial potential against some selected clinical isolates (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae & Candida albicans). Khaya senegalensis is an important multipurpose tree in its natural range in sub-Saharan Africa.

   • Selon Jiang YH (2022)

     Extrait Three new mexicanolide limonoids were obtained from the 90% ethanol extract of the seeds of Khaya senegalensis. Consequently, compounds 1–3 exhibited antimicrobial activity against the tested Gram negative bacteria at the minimum inhibitory concentration values less than 40 μg/ml.

   • Selon Makut DM (2008)

     Extrait The test organisms were Staphylococcus aureus, Steptococcus faecalis, Escherichia coli & Candida albicans. Khaya senegalensis , a member of the family Meliaceae, is a plant commonly used by the local people of Nasarawa State of Nigeria for the treatment of dysentery, mucous diarrhoea & wound infections.

   • Selon Abdallah (2016)

     Extrait Khaya senegalensis leaf extracts contain some bioactive ingredients which include; saponins, alkaloids, tannins & flavonoids.

   • Selon Yuan CM (2013)

     Extrait Eight new limonoids, khayseneganins A–H (1–8), & 31 known limonoids were isolated from the leaves & twigs of Khaya senegalensis. Compounds 9, 10, 12, & 15 showed antimicrobial activities against Pseudomonas aeruginosa, MRSA 92#, & MRSA 98#, all with a MIC value of 12.5 μg/mL.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.