Morinda cirifolia (Ponm makak) : propiedades medicinales en extracción alcohólica

Morinda cirifolia (Ponm makak, Vonmi-chat, manzana de macaco, vómito de gato, pomme -à-macaque, Vomissure de chat, Monkey apple, Cat vomit) — familia Rubiacées.

Fuentes externas reconocidas asociadas a esta monografía: TRAMIL.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 33 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 185 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Pie diabético

   Parte usada: fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Jadhav ND (2017)

     Extrait Jadhav ND et al, Studies of Anti-Diabetic Effect of Morinda citrifolia Fruit Juice on Alloxan Induced Diabetic Rat Int.

   • Selon Nayak BS (2007)

     Extrait This study aimed to evaluate the wound-healing activity of Morinda citrifolia fruit juice in streptozotocin-induced diabetic rats. Histological studies showed that collagen was laid down faster in the experimental diabetic animals than in the normal control & diabetic control groups.

   • Selon OWEN PL (2008)

     Extrait Rapid increase in the incidence of type 2 diabetes (DM2) in Papua New Guinea, coupled with compelling epidemiological evidence supporting a diabetogenic association with betel quid (BQ) chewing has led us to investigate dietary strategies that might offer protection from developing DM2. These plants, along with BQ & its component ingredients areca nut (Areca catechu L) & Piper betle L inflorescence, were assessed for their ability to mediate insulin-dependent & insulin-independent glucose transport in cultured 3T3-L1 adipocytes.

   • Selon Rao USM (2009)

     Extrait The hypoglycemic & antioxidative effects of Morinda citrifolia fruit extract were evaluated in streptozotocin (STZ)-induced diabetic rats. The ethanolic extract of MC fruit at a concentration of 300 mg/kg body weight/rat/day was orally administered to STZ-induced diabetic rats for a period of 30 days.

   • Selon Okamoto H (2012)

     Extrait Morinda citrifolia (Noni) fruits have been used traditionally to treat diabetes, high blood pressure, cancer, mechanical injury, & arthritis.

2. 2

   Diabetes mellitus tipo II

   Parte usada: fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nayak BS (2007)

     Extrait This study aimed to evaluate the wound-healing activity of Morinda citrifolia fruit juice in streptozotocin-induced diabetic rats. Histological studies showed that collagen was laid down faster in the experimental diabetic animals than in the normal control & diabetic control groups.

   • Selon OWEN PL (2008)

     Extrait Rapid increase in the incidence of type 2 diabetes (DM2) in Papua New Guinea, coupled with compelling epidemiological evidence supporting a diabetogenic association with betel quid (BQ) chewing has led us to investigate dietary strategies that might offer protection from developing DM2. These plants, along with BQ & its component ingredients areca nut (Areca catechu L) & Piper betle L inflorescence, were assessed for their ability to mediate insulin-dependent & insulin-independent glucose transport in cultured 3T3-L1 adipocytes.

   • Selon Rao USM (2009)

     Extrait The hypoglycemic & antioxidative effects of Morinda citrifolia fruit extract were evaluated in streptozotocin (STZ)-induced diabetic rats. The ethanolic extract of MC fruit at a concentration of 300 mg/kg body weight/rat/day was orally administered to STZ-induced diabetic rats for a period of 30 days.

   • Selon Okamoto H (2012)

     Extrait Morinda citrifolia (Noni) fruits have been used traditionally to treat diabetes, high blood pressure, cancer, mechanical injury, & arthritis.

   • Selon Algenstaedt P (2018)

     Extrait Methods: M citrifolia fruit juice (NFJ), 2 ml per kg bw per day, was consumed by twenty patients with DT2 after they underwent a standard treatment regimen including carbohydrate reduced diet and treatment with an antidiabetic drug and/or insulin. The effect of the daily consumption of Morinda citrifolia (Noni) fruit juice on the physiological status of patients with diabetes type 2 (DT2) was tested over a period of two months.

3. 3

   Cáncer: potenciación de la quimioterapia antitumoral

   Parte usada: fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Santiago K (2010)

     Extrait Santiago K et al, Evaluation of the Hepatic Metabolism & Antitumor Activity of Noni Juice (Morinda citrifolia L.) in Combination with Chemotherapy, J of the Society for Integr Oncol, 8, (3): 89, 2010,.

   • Selon SATYAMOORTHY K, Bioassay based discovery of anticancer drugs from fruits of Noni, Morinda citrifolia L. WNRF Technical Bull 15, 2014-Abstract

     Extrait Chemopreventive agents are non-Toxic & might exert their effects either by blocking or metabolizing carcinogens or by inhibiting tumor cell growth (Sarkar (2014) — extrait : Growing evidence has shown that chemopreventive agents potentiate the efficacy of Chemotherapy & radiotherapy through the regulation of multiple signaling pathways, including Akt, NF-ºB, cMyc, cyclooxygenase-2, apoptosis & others suggesting a multitargeted nature of chemopreventive agents (Sarkar et al.

   • Selon Beh HK (2012)

     Extrait The present findings further support the use of MC in cancer or other pathological conditions related to angiogenesis.

   • Selon Moongkarndi P (2004)

     Extrait niruri] whole plant, Passiflora foetida aerial part, Ardisia elliptica fruit, Morinda citrifolia fruit, Aegle marmelos fruit, Heliotropium indicum whole plant, Stephania venosa [Stephania rotunda] bulb a& Thunbergia laurifolia leaf) were tested for antiproliferative activity against SKBR3 human breast adenocarcinoma cell line using MTT assay. However, all the plant extracts showed activity in potential range for further investigation on cancer cells, showed activity in potential range for further investigation on cancer cells.

   • Selon Narayankar C (2021)

     Extrait The results showed a significant anticancer & cytotoxic effect of M citrifolia against PC-3 human cancer cell lines, & thus supported the ethnomedical use of M citrifolia,. Morinda citrifolia fruit is well known traditional medicine that has both antioxidant & anticancer activity.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.