Morinda cirifolia (Ponm makak) : vertus médicinales en extraction alcoolique

Morinda cirifolia (Ponm makak, Vonmi-chat, pomme -à-macaque, Vomissure de chat, Monkey apple, Cat vomit) — famille Rubiacées.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 32 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 184 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Pied diabétique

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Jadhav ND (2017)

     Extrait Jadhav ND et al, Studies of Anti-Diabetic Effect of Morinda citrifolia Fruit Juice on Alloxan Induced Diabetic Rat Int.

   • Selon Nayak BS (2007)

     Extrait This study aimed to evaluate the wound-healing activity of Morinda citrifolia fruit juice in streptozotocin-induced diabetic rats. Histological studies showed that collagen was laid down faster in the experimental diabetic animals than in the normal control & diabetic control groups.

   • Selon OWEN PL (2008)

     Extrait Rapid increase in the incidence of type 2 diabetes (DM2) in Papua New Guinea, coupled with compelling epidemiological evidence supporting a diabetogenic association with betel quid (BQ) chewing has led us to investigate dietary strategies that might offer protection from developing DM2. These plants, along with BQ & its component ingredients areca nut (Areca catechu L) & Piper betle L inflorescence, were assessed for their ability to mediate insulin-dependent & insulin-independent glucose transport in cultured 3T3-L1 adipocytes.

   • Selon Rao USM (2009)

     Extrait The hypoglycemic & antioxidative effects of Morinda citrifolia fruit extract were evaluated in streptozotocin (STZ)-induced diabetic rats. The ethanolic extract of MC fruit at a concentration of 300 mg/kg body weight/rat/day was orally administered to STZ-induced diabetic rats for a period of 30 days.

   • Selon Auteur (2012)

     Extrait Morinda citrifolia (Noni) fruits have been used traditionally to treat diabetes, high blood pressure, cancer, mechanical injury, & arthritis.

2. 2

   Diabète mellitus de type II

   Partie usitée : Fruit. Profil pharmacologique documenté : Gliclazide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nayak BS (2007)

     Extrait This study aimed to evaluate the wound-healing activity of Morinda citrifolia fruit juice in streptozotocin-induced diabetic rats. Histological studies showed that collagen was laid down faster in the experimental diabetic animals than in the normal control & diabetic control groups.

   • Selon OWEN PL (2008)

     Extrait Rapid increase in the incidence of type 2 diabetes (DM2) in Papua New Guinea, coupled with compelling epidemiological evidence supporting a diabetogenic association with betel quid (BQ) chewing has led us to investigate dietary strategies that might offer protection from developing DM2. These plants, along with BQ & its component ingredients areca nut (Areca catechu L) & Piper betle L inflorescence, were assessed for their ability to mediate insulin-dependent & insulin-independent glucose transport in cultured 3T3-L1 adipocytes.

   • Selon Rao USM (2009)

     Extrait The hypoglycemic & antioxidative effects of Morinda citrifolia fruit extract were evaluated in streptozotocin (STZ)-induced diabetic rats. The ethanolic extract of MC fruit at a concentration of 300 mg/kg body weight/rat/day was orally administered to STZ-induced diabetic rats for a period of 30 days.

   • Selon Auteur (2012)

     Extrait Morinda citrifolia (Noni) fruits have been used traditionally to treat diabetes, high blood pressure, cancer, mechanical injury, & arthritis.

   • Selon Algenstaedt P (2018)

     Extrait Methods: M citrifolia fruit juice (NFJ), 2 ml per kg bw per day, was consumed by twenty patients with DT2 after they underwent a standard treatment regimen including carbohydrate reduced diet and treatment with an antidiabetic drug and/or insulin. The effect of the daily consumption of Morinda citrifolia (Noni) fruit juice on the physiological status of patients with diabetes type 2 (DT2) was tested over a period of two months.

3. 3

   Cancer : chemoprevention et potentialisation de la radiothérapie anti-cancéreuse

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2012)

     Extrait A Medline search was conducted using the key search words 'Morinda citrifolia'& 'Morinda citrifolia & cancer' (1964 to October, 2011) along with cross-referencing. Among the in vitro studies, a 'concentrated component' in noni juice & not pure noni juice may (1) stimulate the immune system to 'possibly' assist the body fight the cancer, & (2) kill a small percentage (0-36%) of cancer cells depending on the type.

   • Selon SATYAMOORTHY K, Bioassay based discovery of anticancer drugs from fruits of Noni, Morinda citrifolia L. WNRF Technical Bull 15, 2014-Abstract

     Extrait Chemopreventive agents are non-Toxic & might exert their effects either by blocking or metabolizing carcinogens or by inhibiting tumor cell growth (Sarkar (2014) — extrait : Growing evidence has shown that chemopreventive agents potentiate the efficacy of Chemotherapy & radiotherapy through the regulation of multiple signaling pathways, including Akt, NF-ºB, cMyc, cyclooxygenase-2, apoptosis & others suggesting a multitargeted nature of chemopreventive agents (Sarkar et al.

   • Selon Beh HK (2012)

     Extrait The methanol extracts of fruits & leaves of MC & the subsequent chloroform fraction of the fruit methanolic extract were found to have potential anti-angiogenic activity & were more potent compared to suramin. Scopoletin was identified as one of the chemical constituents that may be partly responsible for the anti-angiogenic activity of MC fruits.

   • Selon Kitic D (1932)

     Extrait Recently, there has been an increased focus on exploring Noni extracts & phytoconstituents, particularly for their effectiveness against cancers such as lung, esophageal, liver, & breast cancer, & their potential in cancer chemoprevention. This review focused on in vitro & in vivo studies, as well as clinical trials that explore the effects of MC fruit & its phytoconstituents-including anthraquinones, flavonoids, sugar derivatives, & neolignans-on cancer.

   • Selon Blanco YC (2006)

     Extrait If, in the future, the nutritional and medical values of the noni can be assessed, especially its anti-cancer activity, this fruit could play a noticeable economic role in producing countries,. However, both the fruit & damnacanthal, an anthraquinone compound extracted from noni roots, are currently being studied in the context of anti-cancer research.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.