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Morus alba (Morera) : propiedades medicinales en extracción alcohólica

Morus alba (Morera, Los tres Reyes Magos, Murier, Les Trois rois mages, Mulberry tree, The Three Wise Men) — familia Moracées.

Sinónimos científicos : Morus atropurpurea Roxb, M chinensis Lodd. E Loudon, M latifolia Poir, M multicaulis (Perr.) P, Morus tatarica L..

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 31 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 176 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

  1. Diabetes mellitus tipo II

    Parte usada: Hoja.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon HE X (2018)

      Extrait MA fruits & leaves contain rich bioactive polysaccharides, which are shown to possess various promising bioactivities, mainly including antidiabetic, immunomodulation, anti-inflammation, antioxidation, anti-obesity, hepatoprotection & renoprotection.

    • Selon Habeeb MN (2012)

      Extrait The aim of the present study was to evaluate the hypoglycemic activity of Morus alba extract from different grades of alcohol and to know which grade is a potent inhibitor of - amylase & - glucosidase enzymes.

    • Selon Fauzi A (2024)

      Extrait Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW. Phytochemical compounds in the leaves demonstrated the ability to enhance insulin sensitivity & β-cell secretory function, suggesting their potential value in reducing blood glucose & treating diabetes.

    • Selon Mohammadi J (2008)

      Extrait The objective of the present investigation was to evaluate the therapeutic efficacy of Morus alba leaves in an animal model of diabetes. Results: Blood glucose level &other parameters (except HDL) were elevated in the diabetic group, but were brought to control group level in the diabetic group treated with 600 mg/kg body weight of MA leaf extract.

    • Selon Singab AK (2005)

      Extrait The hypoglycemic activity of the flavonoids rich fraction of 70% alcohol extract of the Egyptian Morus alba root bark (MRBF-3) was evaluated after its oral administration to streptozotocin-induced diabetic rats. The administration of MRBF-3 to streptozotocin (STZ)-diabetic rats for 10 days in a dose of 200 & 400 mg kg (-1) day (-1) was not significant.

  2. Anomalías en los parámetros séricos: SGOP, SGPT, fosfatasa alcalina (SALP)

    Parte usada: Hoja.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon Fathy SA (2013)

      Extrait this study aimed to investigate the effect of aqueous & organic extracts of mulberry leaves (Morus Alba L.) on human hepatocellular carcinoma HepG2 cell line. leaves on HepG2 cell viability, nuclear factor kappa B (NF-κB) gene expression, alfa-fetoprotein (AFP), albumin (ALB), gamma-glutamyl transpeptidase (γ-GT) & alkaline phosphatase(ALP) were measured.

    • Selon Fauzi A (2024)

      Extrait On the other hand, administration of 500 & 1000 mg/kg MLE resulted in mild hepatocellular injury, as indicated by a significant (p < 0.05) increase in liver enzyme activities of alanine aminotransferase (ALT) & aspartate aminotransferase (AST). Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW.

    • Selon Naowaratwattana W (2010)

      Extrait The entire plant of Morus alba L. In this study, we investigated the effect of MA leaf extracts on the human hepatoma HepG2 cell line, which is related to hepatocellular carcinoma.

    • Selon Zeni ALB (2010)

      Extrait Therefore, the treatment not only decreased the plasma level of triglycerides but also affected a hepatic enzyme tested supporting the fact that the extracts of Morus alba that have been used by folk medicine have a great potential to be further developed into a phytomedicine. Morus alba leaves are used in Brazil medicines against fever, to protect the liver, to lower the blood pressure & cholesterol.

    • Selon HU Y (2024)

      Extrait Mulberry (Latin name "Morus alba L.") is a perennial deciduous tree in the family of Moraceae, widely distributed around the world. Polysaccharides, as its main active ingredients, have various effects, such as antioxidant, hypoglycemic, hepatoprotective, & immunomodulatory.

  3. Hepatitis, cirrosis, esteatosis hepática

    Parte usada: Hoja.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon Fauzi A (2024)

      Extrait On the other hand, administration of 500 & 1000 mg/kg MLE resulted in mild hepatocellular injury, as indicated by a significant (p < 0.05) increase in liver enzyme activities of alanine aminotransferase (ALT) & aspartate aminotransferase (AST). Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW.

    • Selon Naowaratwattana W (2010)

      Extrait The entire plant of Morus alba L. In this study, we investigated the effect of MA leaf extracts on the human hepatoma HepG2 cell line, which is related to hepatocellular carcinoma.

    • Selon Zeni ALB (2010)

      Extrait Therefore, the treatment not only decreased the plasma level of triglycerides but also affected a hepatic enzyme tested supporting the fact that the extracts of Morus alba that have been used by folk medicine have a great potential to be further developed into a phytomedicine. Morus alba leaves are used in Brazil medicines against fever, to protect the liver, to lower the blood pressure & cholesterol.

    • Selon HU Y (2024)

      Extrait Mulberry (Latin name "Morus alba L.") is a perennial deciduous tree in the family of Moraceae, widely distributed around the world. Polysaccharides, as its main active ingredients, have various effects, such as antioxidant, hypoglycemic, hepatoprotective, & immunomodulatory.

    • Selon Fathy SA (2013)

      Extrait this study aimed to investigate the effect of aqueous & organic extracts of mulberry leaves (Morus Alba L.) on human hepatocellular carcinoma HepG2 cell line.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.

Evolución de esta ficha pública

Bajo el CTA · historial de cambios públicos

Contenido

+1 indication · ~3 indicaciónes corregidas · ~ posología veterinaria · +2 referencias · ~8 referencias corregidas · −1 referencia

Solo contadores y dominios: los nombres de indicaciones y sinergias no se listan aquí (abrir la ficha en la aplicación). Los textos de las referencias añadidas, corregidas o retiradas están abajo.

+1 indication~3 indicaciónes corregidas~ posología veterinaria+2 referencias~8 referencias corregidas−1 referencia
+2 referencias — mostrar textos
Bioinformatic Study of the Active Compound of Morusin in Mulberry (Morus alba) against Breast Cancer. Indonesian Jl of Cancer Chem, 14(1), 60. 2023-Sarmoko S et al · 2023

Bioinformatic Study of the Active Compound of Morusin in Mulberry (Morus alba) against Breast Cancer. Indonesian Jl of Cancer Chem, 14(1), 60. 2023-

Añadida
Effect of Morus alba L. Fruit Extract on Sperm Quality, Testosterone Profile, & Testicular Histology in Male Rats, Med Environ Sci Biol Life, 2026-Abstract: Morus alba L. fruit extract (MFE), which isSAWATPANICH T et al · 2026

Effect of Morus alba L. Fruit Extract on Sperm Quality, Testosterone Profile, & Testicular Histology in Male Rats, Med Environ Sci Biol Life, 2026-Abstract: Morus alba L. fruit extract (MFE), which is rich in cyanidin 3-glucoside (C3G), demonstrates antioxidant properties & pharmacological effects, but its reproductive safety remains poorly understood. Polyphenols modulate steroidogenesis, spermatogenesis, & sperm acrosome integrity; therefore, toxicity assessment is needed for use. This study aimed to evaluate the antioxidant profiles & subchronic reproductive effects of MFE. MFE was stand…

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ANTHELMINTIC ACTIVITY OF THE LEAVES OF MORUS ALBA LINN, PharmaTutor, 2013-Abstract: Present study was carried out to scientifically evaluate the anthelmintic potential of the methanolic extract of leaSahu N · 2013

ANTHELMINTIC ACTIVITY OF THE LEAVES OF MORUS ALBA LINN, PharmaTutor, 2013-Abstract: Present study was carried out to scientifically evaluate the anthelmintic potential of the methanolic extract of leaves of the plant Morus alba(L) as it is used by the tribal community of different states and this is also highlighted in traditional uses of the plant. Activity was performed using adult earthworms & leaves were used for the study. From results of the study, it is clear that albendazole was used as a standard. Various doses (2.5, 5, 10 mg/ml) of methanolic extracts of potency of the extracts is…

Corregida
an in-vitro evaluation of anthelmintic activity of Morus alba bark, Inter Jl of Pharmaceut Sci, 2(2) :35–7, 2006-Abstract: Different extracts of Morus alba bark were taken for anthelmintic activity agAgarwal K et al · 2006

an in-vitro evaluation of anthelmintic activity of Morus alba bark, Inter Jl of Pharmaceut Sci, 2(2) :35–7, 2006-Abstract: Different extracts of Morus alba bark were taken for anthelmintic activity against Indian earthworm Pheretima posthuma. Three concentrations (2, 4, & 10 mg/ml) of various extracts were tested & results were expressed in terms of time for paralysis & time for death of worms. Piperazine hydrate (2 & 4 mg/ml) was used as reference standard & normal saline as control group. Dose dependent activity was observed in the plant extracts but hydroalcoholic extract exhibited more …

Corregida
Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent des propriétés oestrogéniques, tels que, par exemple, des extraits aqueux et éthanoliques de MBrevet déposé pour l’usage oestrogénique (Estrogenic extracts of Morus Alba & uses thereof)

Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent des propriétés oestrogéniques, tels que, par exemple, des extraits aqueux et éthanoliques de Morus alba dont les cellules ER & g(a)+ et ERß+ possèdent des propriétés oestrogéniques. L'action oestrogénique de ces extraits comprend la stimulation des éléments de réponse oestrogénique (ERE) et la répression du facteur de nécrose des tumeurs (TNF). L'invention concerne des méthodes de traitement des symptômes du climatère, du cancer du sein et/ou de l'utérus, et d’Ostéoporose,

Corregida
The Effects of Supplementary Mulberry Leaf (Morus alba) Extracts on the Trace Element Status (Fe, Zn & Cu) in Relation to Diabetes Management and Antioxidant Indices in Diabetic Rats, Biol Trace ElemeKról E · 2016

The Effects of Supplementary Mulberry Leaf (Morus alba) Extracts on the Trace Element Status (Fe, Zn & Cu) in Relation to Diabetes Management and Antioxidant Indices in Diabetic Rats, Biol Trace Elements Res, 2016; 174 (1) :58-165,

Corregida
MORUS ALBA, Bulgarian Jl of Agric Sci, 4) 2015, 747-50,Nikolova T · 2015

MORUS ALBA, Bulgarian Jl of Agric Sci, 4) 2015, 747-50,

Corregida
COMPARATIVE STUDY OF AMINO ACID COMPOSITION OF BLACK MULBERRY LEAVES (MORUS NIGRA L.), WHITE MULBERRY (MORUS ALBA L.) & MULBERRY RED (MORUS RUBRA L.), Fundamental Res, 3, 2014,Selina I.I. · 2014

COMPARATIVE STUDY OF AMINO ACID COMPOSITION OF BLACK MULBERRY LEAVES (MORUS NIGRA L.), WHITE MULBERRY (MORUS ALBA L.) & MULBERRY RED (MORUS RUBRA L.), Fundamental Res, 3, 2014,

Corregida
Protective Effects of Morus Alba (M. alba) Extract on the Alteration of Testicular Tissue & Spermatogenesis in Adult Rats Treated with Monosodium Glutamate, Med-Science. 2015; 4(1): 1959-65 / doi: 10.Kianifard D · 2015

Protective Effects of Morus Alba (M. alba) Extract on the Alteration of Testicular Tissue & Spermatogenesis in Adult Rats Treated with Monosodium Glutamate, Med-Science. 2015; 4(1): 1959-65 / doi: 10.5455/medscience.2014.03.8191,

Corregida
Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter Jl of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their mAgabeyli RA · 2012

Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter Jl of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their mixture on the structure & functions of plants & animals’ cells were studied. The absence of the genotoxicity of the extracts & their mixture has been established. All active biological compounds studied demonstrate genoprotective properties. The studied extracts & their mixtures decreased the mutability level induced with chemical mutagens, gamma-rays & ageing in the plants (Vicia faba, Arabido…

Corregida
Brevet déposé pour l’usage oestrogénique (Estrogenic extracts of Morus Alba & uses thereof)-Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent deAuteur inconnu

Brevet déposé pour l’usage oestrogénique (Estrogenic extracts of Morus Alba & uses thereof)-Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent des propriétés oestrogéniques, tels que, par exemple, des extraits aqueux et éthanoliques de Morus alba dont les cellules ER&g(a)+ et ERß+ possèdent des propriétés oestrogéniques. L'action oestrogénique de ces extraits comprend la stimulation des éléments de réponse oestrogénique (ERE) et la répression du facteur de nécrose des tumeurs (TNF). L'invention concerne des méthodes de traitement des sy…

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Por Emmanuel Nossin · etnofarmacólogo

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Disponible en español

español

Por Emmanuel Nossin · etnofarmacólogo

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+2 indications · +2 sinergias · ~ posología · +6 referencias · ~1 referencia corregida

Solo contadores y dominios: los nombres de indicaciones y sinergias no se listan aquí (abrir la ficha en la aplicación). Los textos de las referencias añadidas, corregidas o retiradas están abajo.

+2 indications+2 sinergias~ posología+6 referencias~1 referencia corregida
+6 referencias — mostrar textos
Kim YSK et al. Mulberry component Kuwanon C exerts potent therapeutic efficacy in vitro against COVID-19 by blocking the SARS-CoV-2 spike S1 RBD: ACE2 receptor interaction. Int Jl Mol Sci. 23:12516. 2Kim YSK · 2022

Kim YSK et al. Mulberry component Kuwanon C exerts potent therapeutic efficacy in vitro against COVID-19 by blocking the SARS-CoV-2 spike S1 RBD: ACE2 receptor interaction. Int Jl Mol Sci. 23:12516. 2022-Abstract: There has been an immense effort by global pharmaceutical companies to develop anti-COVID-19 drugs, including small molecule-based RNA replication inhibitors via drug repositioning & antibody-based spike protein blockers related to cell entry by SARS-CoV-2. However, several limitations to their clinical use have emerged in addition to a lack of progress in the development of small…

Añadida
Lee JH et al, Antiviral Effects of Mulberry (Morus alba) Juice & Its Fractions on Foodborne Viral Surrogates. Foodborne Pathog. Dis. 11, 224–9. 2014-Abstract: Norovirus infection is a major cause of nLee JH · 2014

Lee JH et al, Antiviral Effects of Mulberry (Morus alba) Juice & Its Fractions on Foodborne Viral Surrogates. Foodborne Pathog. Dis. 11, 224–9. 2014-Abstract: Norovirus infection is a major cause of nonbacterial foodborne outbreaks worldwide, but no specific treatments are available yet. In this study, we investigated the antiviral activity of mulberry (Morus alba, Ma) juice & its fractions on murine norovirus-1 (MNV-1) & feline calicivirus-F9 (FCV-F9) as human norovirus surrogates using cytopathic effect inhibition, plaque reduction, & RNA expression assays. In time-of-addition experiments…

Añadida
Thabti I et al. Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus & Virus-Related Respiratory Tract Infections in the Spotlight. Mol, 25, 1876. 2020-Abstract: Viral respirThabti I · 2020

Thabti I et al. Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus & Virus-Related Respiratory Tract Infections in the Spotlight. Mol, 25, 1876. 2020-Abstract: Viral respiratory infections cause life-threatening diseases in millions of people worldwide every year. Human coronavirus & several picornaviruses are responsible for worldwide epidemic outbreaks, thus representing a heavy burden to their hosts. In the absence of specific treatments for human viral infections, natural products offer an alternative in terms of innovative drug therapies. (2) Methods: We ana…

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Sim WS et al, Anti-Obesity Effect of Extract from Nelumbo Nucifera L., Morus Alba L., & Raphanus Sativus Mixture in 3T3-L1 Adipocytes & C57BL/6J Obese Mice, Foods, 8(5):170, 2019-Abstract: The antioxiSim WS · 2019

Sim WS et al, Anti-Obesity Effect of Extract from Nelumbo Nucifera L., Morus Alba L., & Raphanus Sativus Mixture in 3T3-L1 Adipocytes & C57BL/6J Obese Mice, Foods, 8(5):170, 2019-Abstract: The antioxidant & anti-adipogenic activities of a mixture of Nelumbo nucifera, Morus alba leaves & Raphanus sativus root, were investigated & their anti-obesity activities were established in vitro & in vivo. Among the 26 different mixtures of extraction solvent & mixture ratios, ethanol extract mixture no. 1 (EM01) showed the highest antioxidant (α,α-Diphenyl-β-picrylhydrazyl, total phenolic contents) & …

Añadida
SUSANTI E et al, Potential Combination of Cermai (Phyllanthus acidus) & Mulberry (Morus alba) Fruit Extract as a Candidate for Tyrosinase Inhibitor, Al-Kauniyah Jl of Biol, 18(2):436-47, 2025-AbstractSUSANTI E · 2025

SUSANTI E et al, Potential Combination of Cermai (Phyllanthus acidus) & Mulberry (Morus alba) Fruit Extract as a Candidate for Tyrosinase Inhibitor, Al-Kauniyah Jl of Biol, 18(2):436-47, 2025-Abstract: Melanin, a pigment derived from UV radiation, is crucial in preventing skin damage & can cause aesthetic & dermatological problems such as hyperpigmentation or hypopigmentation. Melanogenesis is a complex process involving enzymes & cytokines, with UV being a primary contributor. Tyrosinase is a key enzyme in melanin synthesis. This study aims to test the potential of combining PA fruit extra…

Añadida
Kalantari H, HEPATOPROTECTIVE EFFECT OF MORUS ALBA L. IN CARBON TETRACHLORIDE- INDUCED HEPATOTOXICITY IN MICE, Saudi Pharmaceut Jl, 17 :1, 2009,Kalantari H · 2009

Kalantari H, HEPATOPROTECTIVE EFFECT OF MORUS ALBA L. IN CARBON TETRACHLORIDE- INDUCED HEPATOTOXICITY IN MICE, Saudi Pharmaceut Jl, 17 :1, 2009,

Añadida
Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter J of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their miAgabeyli RA · 2012

Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter J of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their mixture on the structure & functions of plants & animals’ cells were studied. The absence of the genotoxicity of the extracts & their mixture has been established. All active biological compounds studied demonstrate genoprotective properties. The studied extracts & their mixtures decreased the mutability level induced with chemical mutagens, gamma-rays & ageing in the plants (Vicia faba, Arabidop…

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Por Emmanuel Nossin · etnofarmacólogo

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