Morus alba (Murier) : vertus médicinales en extraction alcoolique
Morus alba (Murier, Les Trois rois mages) — famille Moracées.
Synonymes scientifiques : Morus atropurpurea Roxb, M chinensis Lodd. E Loudon, M latifolia Poir, M multicaulis (Perr.) P, Morus tatarica L..
Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 30 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 175 références scientifiques pour cette espèce (détail intégral dans l’application).
Indications thérapeutiques en extraction alcoolique :
Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).
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Diabète mellitus de type II
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon HE X (2018)
Extrait MA fruits & leaves contain rich bioactive polysaccharides, which are shown to possess various promising bioactivities, mainly including antidiabetic, immunomodulation, anti-inflammation, antioxidation, anti-obesity, hepatoprotection & renoprotection. (family Moraceae), also known as white mulberry, is distinguished as a source of highly promising traditional medicines (including Mori Folium, Mori Fructus, Mori Ramulus & Mori Cortex) & also functional foods.
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Selon Habeeb MN (2012)
Extrait The aim of the present study was to evaluate the hypoglycemic activity of Morus alba extract from different grades of alcohol and to know which grade is a potent inhibitor of - amylase & - glucosidase enzymes.
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Selon Fauzi A (2024)
Extrait Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW. Phytochemical compounds in the leaves demonstrated the ability to enhance insulin sensitivity & β-cell secretory function, suggesting their potential value in reducing blood glucose & treating diabetes.
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Selon Mohammadi J (2008)
Extrait The objective of the present investigation was to evaluate the therapeutic efficacy of Morus alba leaves in an animal model of diabetes. Results: Blood glucose level &other parameters (except HDL) were elevated in the diabetic group, but were brought to control group level in the diabetic group treated with 600 mg/kg body weight of MA leaf extract.
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Selon Singab AK (2005)
Extrait The hypoglycemic activity of the flavonoids rich fraction of 70% alcohol extract of the Egyptian Morus alba root bark (MRBF-3) was evaluated after its oral administration to streptozotocin-induced diabetic rats. The administration of MRBF-3 to streptozotocin (STZ)-diabetic rats for 10 days in a dose of 200 & 400 mg kg (-1) day (-1) was not significant.
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Selon HE X (2018)
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Anormalité des paramètres sériques : SGOP , SGPT, Alkaline-phosphatase (SALP)
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Fathy SA (2013)
Extrait this study aimed to investigate the effect of aqueous & organic extracts of mulberry leaves (Morus Alba L.) on human hepatocellular carcinoma HepG2 cell line. leaves on HepG2 cell viability, nuclear factor kappa B (NF-κB) gene expression, alfa-fetoprotein (AFP), albumin (ALB), gamma-glutamyl transpeptidase (γ-GT) & alkaline phosphatase(ALP) were measured.
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Selon Fauzi A (2024)
Extrait On the other hand, administration of 500 & 1000 mg/kg MLE resulted in mild hepatocellular injury, as indicated by a significant (p < 0.05) increase in liver enzyme activities of alanine aminotransferase (ALT) & aspartate aminotransferase (AST). Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW.
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Selon Naowaratwattana W (2010)
Extrait The entire plant of Morus alba L. In this study, we investigated the effect of MA leaf extracts on the human hepatoma HepG2 cell line, which is related to hepatocellular carcinoma.
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Selon Zeni ALB (2010)
Extrait Therefore, the treatment not only decreased the plasma level of triglycerides but also affected a hepatic enzyme tested supporting the fact that the extracts of Morus alba that have been used by folk medicine have a great potential to be further developed into a phytomedicine. Morus alba leaves are used in Brazil medicines against fever, to protect the liver, to lower the blood pressure & cholesterol.
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Selon HU Y (2024)
Extrait Mulberry (Latin name "Morus alba L.") is a perennial deciduous tree in the family of Moraceae, widely distributed around the world. Polysaccharides, as its main active ingredients, have various effects, such as antioxidant, hypoglycemic, hepatoprotective, & immunomodulatory.
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Selon Fathy SA (2013)
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Hépatite, cirrhose, stéatose hépatique
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Fauzi A (2024)
Extrait On the other hand, administration of 500 & 1000 mg/kg MLE resulted in mild hepatocellular injury, as indicated by a significant (p < 0.05) increase in liver enzyme activities of alanine aminotransferase (ALT) & aspartate aminotransferase (AST). Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW.
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Selon Naowaratwattana W (2010)
Extrait The entire plant of Morus alba L. In this study, we investigated the effect of MA leaf extracts on the human hepatoma HepG2 cell line, which is related to hepatocellular carcinoma.
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Selon Zeni ALB (2010)
Extrait Therefore, the treatment not only decreased the plasma level of triglycerides but also affected a hepatic enzyme tested supporting the fact that the extracts of Morus alba that have been used by folk medicine have a great potential to be further developed into a phytomedicine. Morus alba leaves are used in Brazil medicines against fever, to protect the liver, to lower the blood pressure & cholesterol.
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Selon HU Y (2024)
Extrait Mulberry (Latin name "Morus alba L.") is a perennial deciduous tree in the family of Moraceae, widely distributed around the world. Polysaccharides, as its main active ingredients, have various effects, such as antioxidant, hypoglycemic, hepatoprotective, & immunomodulatory.
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Selon Fathy SA (2013)
Extrait this study aimed to investigate the effect of aqueous & organic extracts of mulberry leaves (Morus Alba L.) on human hepatocellular carcinoma HepG2 cell line.
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Selon Fauzi A (2024)
D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.
Évolution de cette fiche publique
Sous le CTA · journal des mises à jour
+2 indications · +2 synergies · ~ posologie · +6 références · ~1 référence corrigée
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
+6 références — afficher les textes
Kim YSK et al. Mulberry component Kuwanon C exerts potent therapeutic efficacy in vitro against COVID-19 by blocking the SARS-CoV-2 spike S1 RBD: ACE2 receptor interaction. Int Jl Mol Sci. 23:12516. 2022-Abstract: There has been an immense effort by global pharmaceutical companies to develop anti-COVID-19 drugs, including small molecule-based RNA replication inhibitors via drug repositioning & antibody-based spike protein blockers related to cell entry by SARS-CoV-2. However, several limitations to their clinical use have emerged in addition to a lack of progress in the development of small…
AjoutéeLee JH et al, Antiviral Effects of Mulberry (Morus alba) Juice & Its Fractions on Foodborne Viral Surrogates. Foodborne Pathog. Dis. 11, 224–9. 2014-Abstract: Norovirus infection is a major cause of nonbacterial foodborne outbreaks worldwide, but no specific treatments are available yet. In this study, we investigated the antiviral activity of mulberry (Morus alba, Ma) juice & its fractions on murine norovirus-1 (MNV-1) & feline calicivirus-F9 (FCV-F9) as human norovirus surrogates using cytopathic effect inhibition, plaque reduction, & RNA expression assays. In time-of-addition experiments…
AjoutéeThabti I et al. Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus & Virus-Related Respiratory Tract Infections in the Spotlight. Mol, 25, 1876. 2020-Abstract: Viral respiratory infections cause life-threatening diseases in millions of people worldwide every year. Human coronavirus & several picornaviruses are responsible for worldwide epidemic outbreaks, thus representing a heavy burden to their hosts. In the absence of specific treatments for human viral infections, natural products offer an alternative in terms of innovative drug therapies. (2) Methods: We ana…
AjoutéeSim WS et al, Anti-Obesity Effect of Extract from Nelumbo Nucifera L., Morus Alba L., & Raphanus Sativus Mixture in 3T3-L1 Adipocytes & C57BL/6J Obese Mice, Foods, 8(5):170, 2019-Abstract: The antioxidant & anti-adipogenic activities of a mixture of Nelumbo nucifera, Morus alba leaves & Raphanus sativus root, were investigated & their anti-obesity activities were established in vitro & in vivo. Among the 26 different mixtures of extraction solvent & mixture ratios, ethanol extract mixture no. 1 (EM01) showed the highest antioxidant (α,α-Diphenyl-β-picrylhydrazyl, total phenolic contents) & …
AjoutéeSUSANTI E et al, Potential Combination of Cermai (Phyllanthus acidus) & Mulberry (Morus alba) Fruit Extract as a Candidate for Tyrosinase Inhibitor, Al-Kauniyah Jl of Biol, 18(2):436-47, 2025-Abstract: Melanin, a pigment derived from UV radiation, is crucial in preventing skin damage & can cause aesthetic & dermatological problems such as hyperpigmentation or hypopigmentation. Melanogenesis is a complex process involving enzymes & cytokines, with UV being a primary contributor. Tyrosinase is a key enzyme in melanin synthesis. This study aims to test the potential of combining PA fruit extra…
AjoutéeKalantari H, HEPATOPROTECTIVE EFFECT OF MORUS ALBA L. IN CARBON TETRACHLORIDE- INDUCED HEPATOTOXICITY IN MICE, Saudi Pharmaceut Jl, 17 :1, 2009,
AjoutéeAntimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter J of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their mixture on the structure & functions of plants & animals’ cells were studied. The absence of the genotoxicity of the extracts & their mixture has been established. All active biological compounds studied demonstrate genoprotective properties. The studied extracts & their mixtures decreased the mutability level induced with chemical mutagens, gamma-rays & ageing in the plants (Vicia faba, Arabidop…
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