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Morus alba (Murier) : vertus médicinales en extraction alcoolique

Morus alba (Murier, Les Trois rois mages, Mulberry, The Three Wise Men) — famille Moracées.

Synonymes scientifiques : Morus atropurpurea Roxb, M chinensis Lodd. E Loudon, M latifolia Poir, M multicaulis (Perr.) P, Morus tatarica L..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 28 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 169 références scientifiques pour cette espèce (détail intégral dans l’application).

Indications thérapeutiques en extraction alcoolique :

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

  1. Anormalité des paramètres sériques : SGOP , SGPT, Alkaline-phosphatase (SALP)

    Partie usitée : Feuille.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon Fathy SA (2013)

      Extrait this study aimed to investigate the effect of aqueous & organic extracts of mulberry leaves (Morus Alba L.) on human hepatocellular carcinoma HepG2 cell line. leaves on HepG2 cell viability, nuclear factor kappa B (NF-κB) gene expression, alfa-fetoprotein (AFP), albumin (ALB), gamma-glutamyl transpeptidase (γ-GT) & alkaline phosphatase(ALP) were measured.

    • Selon HU Y (2024)

      Extrait Mulberry (Latin name "Morus alba L.") is a perennial deciduous tree in the family of Moraceae, widely distributed around the world. Polysaccharides, as its main active ingredients, have various effects, such as antioxidant, hypoglycemic, hepatoprotective, & immunomodulatory.

    • Selon Zeni ALB (2010)

      Extrait Therefore, the treatment not only decreased the plasma level of triglycerides but also affected a hepatic enzyme tested supporting the fact that the extracts of Morus alba that have been used by folk medicine have a great potential to be further developed into a phytomedicine. Morus alba leaves are used in Brazil medicines against fever, to protect the liver, to lower the blood pressure & cholesterol.

    • Selon Fauzi A (2024)

      Extrait On the other hand, administration of 500 & 1000 mg/kg MLE resulted in mild hepatocellular injury, as indicated by a significant (p < 0.05) increase in liver enzyme activities of alanine aminotransferase (ALT) & aspartate aminotransferase (AST). Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW.

    • Selon Hussein MS (2010)

      Extrait Hussein MS et al, The Protective Effect of Morus Alba & Calendula Officinalis Plant Extracts on Carbon Tetrachloride- Induced Hepatotoxicity in Isolated Rat Hepatocytes, Jl of Am Sci, 6(0) :2010-.

  2. Diabète mellitus de type II

    Partie usitée : Feuille.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon HE X (2018)

      Extrait MA fruits & leaves contain rich bioactive polysaccharides, which are shown to possess various promising bioactivities, mainly including antidiabetic, immunomodulation, anti-inflammation, antioxidation, anti-obesity, hepatoprotection & renoprotection. (family Moraceae), also known as white mulberry, is distinguished as a source of highly promising traditional medicines (including Mori Folium, Mori Fructus, Mori Ramulus & Mori Cortex) & also functional foods.

    • Selon Habeeb MN (2012)

      Extrait The aim of the present study was to evaluate the hypoglycemic activity of Morus alba extract from different grades of alcohol and to know which grade is a potent inhibitor of - amylase & - glucosidase enzymes.

    • Selon Fauzi A (2024)

      Extrait Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW. Phytochemical compounds in the leaves demonstrated the ability to enhance insulin sensitivity & β-cell secretory function, suggesting their potential value in reducing blood glucose & treating diabetes.

    • Selon Mohammadi J (2008)

      Extrait The objective of the present investigation was to evaluate the therapeutic efficacy of Morus alba leaves in an animal model of diabetes. Results: Blood glucose level &other parameters (except HDL) were elevated in the diabetic group, but were brought to control group level in the diabetic group treated with 600 mg/kg body weight of MA leaf extract.

    • Selon Singab AK (2005)

      Extrait The hypoglycemic activity of the flavonoids rich fraction of 70% alcohol extract of the Egyptian Morus alba root bark (MRBF-3) was evaluated after its oral administration to streptozotocin-induced diabetic rats. The administration of MRBF-3 to streptozotocin (STZ)-diabetic rats for 10 days in a dose of 200 & 400 mg kg (-1) day (-1) was not significant.

  3. Hépatite, cirrhose, stéatose hépatique

    Partie usitée : Feuille.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon HU Y (2024)

      Extrait Mulberry (Latin name "Morus alba L.") is a perennial deciduous tree in the family of Moraceae, widely distributed around the world. Polysaccharides, as its main active ingredients, have various effects, such as antioxidant, hypoglycemic, hepatoprotective, & immunomodulatory.

    • Selon Hussein MS (2010)

      Extrait Hussein MS et al, The Protective Effect of Morus Alba & Calendula Officinalis Plant Extracts on Carbon Tetrachloride- Induced Hepatotoxicity in Isolated Rat Hepatocytes, Jl of Am Sci, 6(0) :2010-.

    • Selon Fauzi A (2024)

      Extrait On the other hand, administration of 500 & 1000 mg/kg MLE resulted in mild hepatocellular injury, as indicated by a significant (p < 0.05) increase in liver enzyme activities of alanine aminotransferase (ALT) & aspartate aminotransferase (AST). Results: Morus alba leaf depicted total phenolic 10.93 mg gallic acid equivalents (GAE)/g dry weight (DW), flavonoid 256.67 mg quercetin equivalents (QE)/g DW, & antioxidant bioactivity content of 602.03 IC50 μg/mL & 13.21 mg Fe2+/g DW.

    • Selon Naowaratwattana W (2010)

      Extrait The entire plant of Morus alba L. In this study, we investigated the effect of MA leaf extracts on the human hepatoma HepG2 cell line, which is related to hepatocellular carcinoma.

    • Selon Zeni ALB (2010)

      Extrait Therefore, the treatment not only decreased the plasma level of triglycerides but also affected a hepatic enzyme tested supporting the fact that the extracts of Morus alba that have been used by folk medicine have a great potential to be further developed into a phytomedicine. Morus alba leaves are used in Brazil medicines against fever, to protect the liver, to lower the blood pressure & cholesterol.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.

Évolution de cette fiche publique

Sous le CTA · journal des mises à jour

Contenu

+1 indication · ~3 indications corrigées · ~ posologie vétérinaire · +2 références · ~8 références corrigées · −1 référence

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes des références ajoutées, corrigées ou retirées sont ci-dessous.

+1 indication~3 indications corrigées~ posologie vétérinaire+2 références~8 références corrigées−1 référence
+2 références — afficher les textes
Bioinformatic Study of the Active Compound of Morusin in Mulberry (Morus alba) against Breast Cancer. Indonesian Jl of Cancer Chem, 14(1), 60. 2023-Sarmoko S et al · 2023

Bioinformatic Study of the Active Compound of Morusin in Mulberry (Morus alba) against Breast Cancer. Indonesian Jl of Cancer Chem, 14(1), 60. 2023-

Ajoutée
Effect of Morus alba L. Fruit Extract on Sperm Quality, Testosterone Profile, & Testicular Histology in Male Rats, Med Environ Sci Biol Life, 2026-Abstract: Morus alba L. fruit extract (MFE), which isSAWATPANICH T et al · 2026

Effect of Morus alba L. Fruit Extract on Sperm Quality, Testosterone Profile, & Testicular Histology in Male Rats, Med Environ Sci Biol Life, 2026-Abstract: Morus alba L. fruit extract (MFE), which is rich in cyanidin 3-glucoside (C3G), demonstrates antioxidant properties & pharmacological effects, but its reproductive safety remains poorly understood. Polyphenols modulate steroidogenesis, spermatogenesis, & sperm acrosome integrity; therefore, toxicity assessment is needed for use. This study aimed to evaluate the antioxidant profiles & subchronic reproductive effects of MFE. MFE was stand…

Ajoutée
ANTHELMINTIC ACTIVITY OF THE LEAVES OF MORUS ALBA LINN, PharmaTutor, 2013-Abstract: Present study was carried out to scientifically evaluate the anthelmintic potential of the methanolic extract of leaSahu N · 2013

ANTHELMINTIC ACTIVITY OF THE LEAVES OF MORUS ALBA LINN, PharmaTutor, 2013-Abstract: Present study was carried out to scientifically evaluate the anthelmintic potential of the methanolic extract of leaves of the plant Morus alba(L) as it is used by the tribal community of different states and this is also highlighted in traditional uses of the plant. Activity was performed using adult earthworms & leaves were used for the study. From results of the study, it is clear that albendazole was used as a standard. Various doses (2.5, 5, 10 mg/ml) of methanolic extracts of potency of the extracts is…

Corrigée
an in-vitro evaluation of anthelmintic activity of Morus alba bark, Inter Jl of Pharmaceut Sci, 2(2) :35–7, 2006-Abstract: Different extracts of Morus alba bark were taken for anthelmintic activity agAgarwal K et al · 2006

an in-vitro evaluation of anthelmintic activity of Morus alba bark, Inter Jl of Pharmaceut Sci, 2(2) :35–7, 2006-Abstract: Different extracts of Morus alba bark were taken for anthelmintic activity against Indian earthworm Pheretima posthuma. Three concentrations (2, 4, & 10 mg/ml) of various extracts were tested & results were expressed in terms of time for paralysis & time for death of worms. Piperazine hydrate (2 & 4 mg/ml) was used as reference standard & normal saline as control group. Dose dependent activity was observed in the plant extracts but hydroalcoholic extract exhibited more …

Corrigée
Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent des propriétés oestrogéniques, tels que, par exemple, des extraits aqueux et éthanoliques de MBrevet déposé pour l’usage oestrogénique (Estrogenic extracts of Morus Alba & uses thereof)

Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent des propriétés oestrogéniques, tels que, par exemple, des extraits aqueux et éthanoliques de Morus alba dont les cellules ER & g(a)+ et ERß+ possèdent des propriétés oestrogéniques. L'action oestrogénique de ces extraits comprend la stimulation des éléments de réponse oestrogénique (ERE) et la répression du facteur de nécrose des tumeurs (TNF). L'invention concerne des méthodes de traitement des symptômes du climatère, du cancer du sein et/ou de l'utérus, et d’Ostéoporose,

Corrigée
The Effects of Supplementary Mulberry Leaf (Morus alba) Extracts on the Trace Element Status (Fe, Zn & Cu) in Relation to Diabetes Management and Antioxidant Indices in Diabetic Rats, Biol Trace ElemeKról E · 2016

The Effects of Supplementary Mulberry Leaf (Morus alba) Extracts on the Trace Element Status (Fe, Zn & Cu) in Relation to Diabetes Management and Antioxidant Indices in Diabetic Rats, Biol Trace Elements Res, 2016; 174 (1) :58-165,

Corrigée
MORUS ALBA, Bulgarian Jl of Agric Sci, 4) 2015, 747-50,Nikolova T · 2015

MORUS ALBA, Bulgarian Jl of Agric Sci, 4) 2015, 747-50,

Corrigée
COMPARATIVE STUDY OF AMINO ACID COMPOSITION OF BLACK MULBERRY LEAVES (MORUS NIGRA L.), WHITE MULBERRY (MORUS ALBA L.) & MULBERRY RED (MORUS RUBRA L.), Fundamental Res, 3, 2014,Selina I.I. · 2014

COMPARATIVE STUDY OF AMINO ACID COMPOSITION OF BLACK MULBERRY LEAVES (MORUS NIGRA L.), WHITE MULBERRY (MORUS ALBA L.) & MULBERRY RED (MORUS RUBRA L.), Fundamental Res, 3, 2014,

Corrigée
Protective Effects of Morus Alba (M. alba) Extract on the Alteration of Testicular Tissue & Spermatogenesis in Adult Rats Treated with Monosodium Glutamate, Med-Science. 2015; 4(1): 1959-65 / doi: 10.Kianifard D · 2015

Protective Effects of Morus Alba (M. alba) Extract on the Alteration of Testicular Tissue & Spermatogenesis in Adult Rats Treated with Monosodium Glutamate, Med-Science. 2015; 4(1): 1959-65 / doi: 10.5455/medscience.2014.03.8191,

Corrigée
Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter Jl of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their mAgabeyli RA · 2012

Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter Jl of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their mixture on the structure & functions of plants & animals’ cells were studied. The absence of the genotoxicity of the extracts & their mixture has been established. All active biological compounds studied demonstrate genoprotective properties. The studied extracts & their mixtures decreased the mutability level induced with chemical mutagens, gamma-rays & ageing in the plants (Vicia faba, Arabido…

Corrigée
Brevet déposé pour l’usage oestrogénique (Estrogenic extracts of Morus Alba & uses thereof)-Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent deAuteur inconnu

Brevet déposé pour l’usage oestrogénique (Estrogenic extracts of Morus Alba & uses thereof)-Abstract : L’invention concerne des extraits de diverses espèces de la famille des moracées qui possèdent des propriétés oestrogéniques, tels que, par exemple, des extraits aqueux et éthanoliques de Morus alba dont les cellules ER&g(a)+ et ERß+ possèdent des propriétés oestrogéniques. L'action oestrogénique de ces extraits comprend la stimulation des éléments de réponse oestrogénique (ERE) et la répression du facteur de nécrose des tumeurs (TNF). L'invention concerne des méthodes de traitement des sy…

Retirée

Par Emmanuel Nossin · ethnopharmacologue

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Fiche disponible en espagnol

espagnol

Par Emmanuel Nossin · ethnopharmacologue

Contenu

+2 indications · +2 synergies · ~ posologie · +6 références · ~1 référence corrigée

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes des références ajoutées, corrigées ou retirées sont ci-dessous.

+2 indications+2 synergies~ posologie+6 références~1 référence corrigée
+6 références — afficher les textes
Kim YSK et al. Mulberry component Kuwanon C exerts potent therapeutic efficacy in vitro against COVID-19 by blocking the SARS-CoV-2 spike S1 RBD: ACE2 receptor interaction. Int Jl Mol Sci. 23:12516. 2Kim YSK · 2022

Kim YSK et al. Mulberry component Kuwanon C exerts potent therapeutic efficacy in vitro against COVID-19 by blocking the SARS-CoV-2 spike S1 RBD: ACE2 receptor interaction. Int Jl Mol Sci. 23:12516. 2022-Abstract: There has been an immense effort by global pharmaceutical companies to develop anti-COVID-19 drugs, including small molecule-based RNA replication inhibitors via drug repositioning & antibody-based spike protein blockers related to cell entry by SARS-CoV-2. However, several limitations to their clinical use have emerged in addition to a lack of progress in the development of small…

Ajoutée
Lee JH et al, Antiviral Effects of Mulberry (Morus alba) Juice & Its Fractions on Foodborne Viral Surrogates. Foodborne Pathog. Dis. 11, 224–9. 2014-Abstract: Norovirus infection is a major cause of nLee JH · 2014

Lee JH et al, Antiviral Effects of Mulberry (Morus alba) Juice & Its Fractions on Foodborne Viral Surrogates. Foodborne Pathog. Dis. 11, 224–9. 2014-Abstract: Norovirus infection is a major cause of nonbacterial foodborne outbreaks worldwide, but no specific treatments are available yet. In this study, we investigated the antiviral activity of mulberry (Morus alba, Ma) juice & its fractions on murine norovirus-1 (MNV-1) & feline calicivirus-F9 (FCV-F9) as human norovirus surrogates using cytopathic effect inhibition, plaque reduction, & RNA expression assays. In time-of-addition experiments…

Ajoutée
Thabti I et al. Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus & Virus-Related Respiratory Tract Infections in the Spotlight. Mol, 25, 1876. 2020-Abstract: Viral respirThabti I · 2020

Thabti I et al. Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus & Virus-Related Respiratory Tract Infections in the Spotlight. Mol, 25, 1876. 2020-Abstract: Viral respiratory infections cause life-threatening diseases in millions of people worldwide every year. Human coronavirus & several picornaviruses are responsible for worldwide epidemic outbreaks, thus representing a heavy burden to their hosts. In the absence of specific treatments for human viral infections, natural products offer an alternative in terms of innovative drug therapies. (2) Methods: We ana…

Ajoutée
Sim WS et al, Anti-Obesity Effect of Extract from Nelumbo Nucifera L., Morus Alba L., & Raphanus Sativus Mixture in 3T3-L1 Adipocytes & C57BL/6J Obese Mice, Foods, 8(5):170, 2019-Abstract: The antioxiSim WS · 2019

Sim WS et al, Anti-Obesity Effect of Extract from Nelumbo Nucifera L., Morus Alba L., & Raphanus Sativus Mixture in 3T3-L1 Adipocytes & C57BL/6J Obese Mice, Foods, 8(5):170, 2019-Abstract: The antioxidant & anti-adipogenic activities of a mixture of Nelumbo nucifera, Morus alba leaves & Raphanus sativus root, were investigated & their anti-obesity activities were established in vitro & in vivo. Among the 26 different mixtures of extraction solvent & mixture ratios, ethanol extract mixture no. 1 (EM01) showed the highest antioxidant (α,α-Diphenyl-β-picrylhydrazyl, total phenolic contents) & …

Ajoutée
SUSANTI E et al, Potential Combination of Cermai (Phyllanthus acidus) & Mulberry (Morus alba) Fruit Extract as a Candidate for Tyrosinase Inhibitor, Al-Kauniyah Jl of Biol, 18(2):436-47, 2025-AbstractSUSANTI E · 2025

SUSANTI E et al, Potential Combination of Cermai (Phyllanthus acidus) & Mulberry (Morus alba) Fruit Extract as a Candidate for Tyrosinase Inhibitor, Al-Kauniyah Jl of Biol, 18(2):436-47, 2025-Abstract: Melanin, a pigment derived from UV radiation, is crucial in preventing skin damage & can cause aesthetic & dermatological problems such as hyperpigmentation or hypopigmentation. Melanogenesis is a complex process involving enzymes & cytokines, with UV being a primary contributor. Tyrosinase is a key enzyme in melanin synthesis. This study aims to test the potential of combining PA fruit extra…

Ajoutée
Kalantari H, HEPATOPROTECTIVE EFFECT OF MORUS ALBA L. IN CARBON TETRACHLORIDE- INDUCED HEPATOTOXICITY IN MICE, Saudi Pharmaceut Jl, 17 :1, 2009,Kalantari H · 2009

Kalantari H, HEPATOPROTECTIVE EFFECT OF MORUS ALBA L. IN CARBON TETRACHLORIDE- INDUCED HEPATOTOXICITY IN MICE, Saudi Pharmaceut Jl, 17 :1, 2009,

Ajoutée
Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter J of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their miAgabeyli RA · 2012

Antimutagenic Activities Extracts from Leaves of the Morus alba, Morus nigra & Their Mixtures, Inter J of Biol, 4 :2, 2012-Abstract: The influence of Morus alba & Morus nigra leaf extracts, & their mixture on the structure & functions of plants & animals’ cells were studied. The absence of the genotoxicity of the extracts & their mixture has been established. All active biological compounds studied demonstrate genoprotective properties. The studied extracts & their mixtures decreased the mutability level induced with chemical mutagens, gamma-rays & ageing in the plants (Vicia faba, Arabidop…

Corrigée

Par Emmanuel Nossin · ethnopharmacologue

Contenu

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anglais

Par Emmanuel Nossin · ethnopharmacologue

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