Ocimum basilicum (Bazilik) : propiedades medicinales en extracción alcohólica

Effects of Ocimum Basilicum on Functional Dyspepsia: A Double-Blind Placebo-Controlled Study: Inter J Med Sci, 30 (3) :134-7, 2005,

Integration of some biopesticides against potato tuber moth, Phthorimaea operculella (Zell.), during storage with reference to histopathological changes detected by a transmission electron microscope in the endocrine system, Bull of the Nat Res Centre, 43, 122, 2019.-Abstract: The potato tuber moth (PTM), Phthorimaea operculella (Zeller) (Lepidoptera: Gelechiidae), is an important pest. It attacks several cultivated Solanaceous plants including potato (Solanum tuberosum), tobacco (Nicotiana tabaccum), eggplant (Solanum melongena), tomato (Lycopersicum esculentum), and bell pepper (Capsicum …

EVALUATION OF IN VITRO CYTOTOXIC ACTIVITY OF OCIMUM BASILICUM & MENTHA SPICATA EXTRACTS, Asian J of Pharmaceut & Clin Res, 2016; 9(3): 131-4-Abstract: The objective of the current research was to evaluate the cytotoxicity of Ocimum basilicum (OB) & Mentha spicata (MS). Methods: In vitro cytotoxic potential of OB & MS extracts was evaluated against human cancer HL60 cell lines using 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay. The treated cell morphology was observed by light microscope. Results: The OB & MS extracts inhibited proliferation of HL60 cells in concentrat…

Effect of Basil (Ocimum basilicum L ) Leave Powder Ethanolic Extract on the 3rd Larval Instar of Anopheles arabiensis (Patton, 1905) Culicidae: Diptera, Int J of Mosq Res, 2013.-Abstract : The present study is designed to investigate the potentialities of Ocimum basilicum leaves powder (LP) & leaf powder –ethanolic extract (LPE) as a larvicide of Anopheles arabiensis 3rd instar larvae (L3) & comparing their results with those of the commonly used (OP) organophosphates larvicide Temephos. A cross sectional study was conducted in Barakat area to collect the Anopheles larvae, identified at the…

Chemical investigation of Ocimum species Growing in Togo. Flav. Frag. J., 13: 226-32, 1998.

Aqueous & ethanolic leaf extracts of Ocimum basilicum (sweet basil) protect against sodium arsenite-induced hepatotoxicity in Wistar rats Nig. J. Physio. Sci., 2010; 25:29-36-Abstract: We evaluated the effects of aqueous & ethanolic leaf extracts of Ocimum basilicum on sodium arsenite-induced hepatotoxicity in Wistar rats. We observed that treatment of the animals with the extracts before or just after sodium arsenite administration significantly (p < 0.05) reduced mean liver & serum γ-Glutamyl transferase (γGT) & serum alkaline phosphatase (ALP) activities when compared with the group admi…

In vitro evaluation of antioxidant, anti-neuro-degenerative & antidiabetic activities of Ocimum basilicum L., Laurus nobilis L. leaves & Citrus reticulata Blanco peel extracts DO 2019-Abstract: Ocimum basilicum (sweet basil) and Laurus nobilis (bay leaves or laurel) have been used in traditional medicine for centuries, & also extensively employed as spices for adding aroma & flavor to various food products. Citrus reticulata (mandarin) is mainly used in food industry for juice production, while its peel as main byproduct contains high concentration of valuable substances. The samples were …

CARDIOPROTECTIVE & ANTILIPIDEMIC ROLE OF OCIMUM BASILICUM SEEDS OIL & LINUM USITATISSIMUM SEEDS OIL IN ACUTE MYOCARDIAL INFARCTION MALE RABBITS INDUCED BY ISOPROTERENOL, Research-Gate, 2018-Abstract: This study was undertaken to investigate the possible protective effect of Ocimum basilicum seeds oil & Linum usitatissimum seeds oil on heart function, antioxidant & lipid profile test, when induced acute myocardial infarction in rabbits by isoproterenol. Thirty-six male rabbits were divided into six groups: group (C): control negative, group (ISO): received isoproterenol (control positive), (…

Nematicides principal from two species of Lamiaceae. J Nematol. 1982; 14:118–20-Abstract: Aqueous extracts of Ocimum sanctum & O. basilicum leaves contained compounds that killed Meloidogyne incognita larvae in 160 min. thin layer & gas-liquid chromatography, & infrared spectrophotometry indicated that the essential oils eugenol & linalool were the active nematicidal compounds.

Studies on chemical, polyphenol content, flavonoid content, & antioxidant activity of sweet basil leaves (Ocimum basilicum L.). IOP Conf Series: Materials Sci & Engineering 2021, 1092 (1), 012083,

CHEMICAL COMPOSITION & ANTI-INFLAMMATORY ACTIVITY OF ESSENTIAL OILS FROM THE LEAVES OF OCIMUM BASILICUM L. & OCIMUM GRATISSIMUM L. (LAMIACEAE), INTER J OF PHARMACEUT SCI & RES,

CHEMICAL COMPOSITION OF ESSENTIAL OIL OF OCIMUM BASILICUML. (BASIL) & IT’S BIOLOGICAL ACTIVITIES–AN OVERVIEW, J of Critical Review, 3:3, 2016.-Abstract: Essential oils are complex mixtures of biological active substances used for fragrance and traditional medicine since long back. It contains mainly triterpenes and aromatic compounds, the chemical composition of the essential oils varies with seasonal, geographical & climatic conditions. Recently there are more researches focused on their chemical profiles & its medicinal properties. Due to their antimicrobial, antifungal, insecticidal, lar…

Phytobiotic Activity of Piper Auritum & Ocimum Basilicum on Avian E. Coli, Bras J of Poultice Sci, 22:01, 2020-Abstract: The objective of this study was to evaluate the phytobiotic activity, in vitro & in vivo, of an extract & an essential oil of Piper auritum & Ocimum basilicum on avian Escherichia coli serotype O2 in broiler chickens experimentally infected. For the in vitro test, extracts at 4, 8, 12 & 16% in water-based solvent or alcohol at 70% were prepared from leaves of both plants. In the essential oils, solvents at 10% were used. A concentration of 1×108 CFU mL-1 of bacteria was s…

Cardiac stimulant activity of Ocimum basilicum Linn. Extracts, Indian J Pharmacol, 2004; 36(3):163-Abstract: To evaluate the cardiac effects of extracts derived from the aerial parts of Ocimum basilicum, MATERIAL & METHODS: The aerial parts of Ocimum basilicum Linn. were extracted with 95% ethanol & double distilled water. The extracts were screened for their effects on frog-heart in situ preparation. Enzyme studies such as Na+/K+ ATPase, Ca2+ATPase & Mg2+ATPase were done on the heart tissue aspartate transaminase (AST), alanine transaminase (ALT), lactate dehydrogenase (LDH) & creatine pho…

Cytotoxic activity of essential oil & extracts of Ocimum Basilicum against human carcinoma cells. Molecular docking study of iso-eugenol as a potent cox & lox inhibitor, Digest J of Nanomaterials & Biostructures, 2014.-Abstract: The antiproliferative activity of the ethanolic extract & the essential oil of O. basilicum, cultivated in Greece, was evaluated in vitro against four different humans’ cancer cell lines: the human cervix adenocarcinoma HeLa cells, human melanoma FemX cells, human chronic myelogenous leukaemia K562 cells & human ovarian SKOV3 cells. Qualitative analysis has been car…

Immunomodulatory & anti-inflammatory effects of hydro-ethanolic extract of Ocimum basilicum leaves & its effect on lung pathological changes in an ovalbumin-induced rat model of asthma, BMC Comp Altern Med, 19(1):349, 2019-Abstract: Ocimum species (Lamiaceae) has been traditionally used for treatment of upper respiratory tract infections, bronchitis, coughs, sore throat, & wound healing. The Immunomodulatory & anti-inflammatory effects of hydro-ethanolic extract of Ocimum basilicum leaves was examined in ovalbumin sensitized animals. Methods: Wistar rats were divided to six groups; non-sens…

Toxicological Evaluation & Hepatoprotective Efficacy of Rosmarinic Acid-Rich Extract from Ocimum basilicum L, Evid Based Comp Alter Med, 2021:6676998-Abstract: Exposure to carbon tetrachloride (CCl4) induces acute & chronic liver injuries as well as oxidative stress in rats. The present study was designed to evaluate the in vivo toxicity of rosmarinic acid-rich extract from Ocimum basilicum (RAE). The acute & subchronic oral toxicity of RAE was evaluated in Albino’s mice. Hepatotoxicity was induced by the administration of CCl4-induced hepatic injury in rats. The hepatoprotective effect of …

Hypoglycemic effect of basil (Ocimum basilicum) aqueous extract is mediated through inhibition of α-glucosidase & α-amylase activities- An in vitro study, Toxicol & Ind Health, 2011, 28(1):42-50,

Chemical composition of five essential oils & their antioxidant & in vitro & in vivo antifungal activities against Alternaria alternata in tomato crop, Nat Prod Res, 39:4, 2025-Abstract: This study aimed to determine the chemical composition of essential oils from A. gratissima, O. basilicum, S. microphylla, T. riparia, & T. vulgaris & their antioxidant & antifungal activities against Alternaria alternata strains. Gas chromatography-mass spectrometry revealed that the major components of the essential oils were terpenes. The EO of S. microphylla & T. riparia showed higher antioxidant activi…

Evaluation of Antimalarial Activity of Sesquiterpene Lactones of Wild Sudanese Basil (Ocimum basilicum L.) through Their in vitro Inhibition of Dihydrofolate Reductase (DHFR), J Of BIOL Agric & HEALTHCARE, 5:1,2015-Abstract: Sudan is one of the countries severely afflicted with malaria. The spread of resistance of the malaria parasite Plasmodium falciparum to currently used antimalarial drugs calls for continued efforts to discover new ones. Basil (Ocimum basilicum L), which grows widely as a rainy season wild annual plant, is used, limitedly though, as one of the folk remedies of malaria i…

Evaluation of repellent activities of the essential oil of Ocimum basilicum against Anopheles mosquito & formulation of mosquito repellent cream. Biomed Res Clin Pract. 2019; 4(2): 1-5. Abstract: This study was conducted to evaluate the repellent activities of the essential oils of Ocimum basilicum against Anopheles mosquito & to formulate cream repellent for mosquitoes from essential oil of O. basilicum L. (Lamiaceae). OB, commonly known as sweet basil, has been used as a traditional medicinal plant for the treatment of headaches, coughs, diarrhoea, constipation, warts, worms, & kidney mal…

Effect of Basil Leaves Extract on Liver Fibrosis Induced by Thioacetamide in Male Rats. Intern J of Pharmacol, 15: 478-85. 2019.-Abstract: The present study aimed to investigate the effect of basil aqueous leaves extract on liver fibrosis induced by thioacetamide (TAA) in male rats. Materials & Methods: About 40 rats were randomly divided into four experimental groups. Rats of group 1 were served as controls. Rats of group 2 were given 300 mg kg body weight of TAA by intraperitoneal injection, twice weekly. Rats of group 3 were orally supplemented with basil leaves extract at a dose of 300 …

Essential Oil Composition of Ocimum basilicum L. & Ocimum minimum L. in Turkey, Czech J. Food Sci. 20(6): 223–8,

Improvement of memory & neurological deficit with Ocimum basilicum L. extract after ischemia reperfusion induced cerebral injury in mice. Metab Brain Dis. 2018; 33(4):1111-20. Abstract: Ocimum basilicum L. is used traditionally to treat CNS disorders. Its antioxidant capacity is well established. Our laboratory has reported protective effects of pre-treatment with O. basilicum in experimental stroke, but its curative (post-treatment) effects in ischemic stroke have not been documented. Hence, the present study was aimed to evaluate the effect of OB leaf extract (OBLE) on functional outcomes…

Effect of Methanolic Leaf Extract of Ocimum basilicum L. on Benzene-Induced Hematotoxicity in Mice, Evidence-Based Comp & Alter Med, 201-doi:10.1155/2012/176385,

Antiulcerogenic effects of Ocimum basilicum extracts, volatile oïl & Flavonoid glycosides in albino rats, Int J Pharmacogn, 30 :7-104, 1992.-Abstract: Antiulcerogenic effects of extracts, volatile oils & flavonoid glycosides of Ocimum basilicum leaves were studied in normal as well as Aspirin-, acetic acid- & stress-induced ulcerated rats. Also, their effects on outputs of gastric acid, pepsin & hexosamines were recorded in normal & ulcerated rats. The aqueous, methanol & water-methanol extracts & flavonoid glycosides of OB decreased the ulcer index, inhibited gastric acid & pepsin secretio…

Analysis of KRas gene from induced pancreatic cancer rats administered with Momordica charantia & Ocimum basilicum leaf extracts, J Tradit Comp Med. 2018; 8(2): 282–8.-Abstract: To analyze K-ras gene from induced pancreatic cancer rats administered with Momordica charantia & Ocimum basilicum leaf extracts. Methods: Twenty-five (25) adult rats weighing between 90–120 g were divided into 5 groups namely RA, RB, RC, NC & PC, each group had 5 rats. The PC which served as the control was fed with normal fish meal & water ad libitum; the NC which is the negative control received 20 mg/ml/week of …

ameliorating effects of Acacia arabica & Ocimum basilicum on acetic acid-induced ulcerative colitis model through mitigation of inflammation & oxidative stress, 11): Research has shown the anti-oxidative & anti-inflammatory effects induced by consuming the Acacia arabica & Ocimum basilicum. The present study aimed to evaluate the effect of treatment with O. basilicum together with A. arabica on healing, inflammation, & oxidative stress in the course of experimental colitis in rats. Methods: A total number of 50 male rats were selected & randomly assigned to five groups of 10 rats each. …

Ethanol extract of basil (Ocimum Basilicum L.) leaves inhibits endometriosis growth in a mouse model by modulating vascular endothelial growth factor (VEGF) expression, J of Med Life, 16(8):1224-30-Abstract: The objective of this study was to examine the effect of administering an ethanol extract obtained from basil leaves on the expression of vascular endothelial growth factor (VEGF) & the severity of endometriosis lesions in a mouse model. A total of 28 female mice, aged 2-3 months & weighing 20-30 grams, were randomly divided into four groups: the control group (C), treatment group 1 (T1…

the effects of green Ocimum basilicum hydroalcoholic extract on re & retrieval of memory in mice, Ancient Sci Life [serial online] 2012; cited 2014, 31:185-9-Abstract: The purpose of this study was evaluation of green Ocimum basilicum (sweet basil) hydroalcoholic extract on memory retention & retrieval of mice by using passive avoidance apparatus. For this purpose, after weighting, coding and classifying the mice, they were grouped (n = 8) as follow as: test groups (electric shock plus sweet basil extract by doses: 100, 200, 400 & 800 mg/kg, i.p.), control group (Only electric shock) & blan…

Effect of leave extract of Ocimum basilicum on Deltamethrin induced nephrotoxicity & oxidative stress in albino rats. J. Appl. Pharm. Sci., 2 :5, 2012.-Abstract: Deltamethrin is à pyrethroid insecticide used extensively in pest control. On the other hand, it showed different toxicity in mammalian animals. Basil or sweet basil (Ocimum basilicum) is a plant which showed many pharmacological effects. The present work studied the potential protective effect of Ocimum basilicum extract on Deltamethrin-induced nephrotoxicity in albino rats. Treating animals with Deltamethrin induced several histo…

Antioxidant effect of Ocimum basilicum essential oil & its effect on cooking qualities of supplemented chicken nuggets. Antioxidants, 11(10): 1882. 2022-Abstract: Basil (Ocimum basilicum L.) is one of the traditional culinary herbs exhibiting food preservation properties. The current study investigated the EO composition, antioxidant activity and in vitro cytotoxic capacity of the essential oil of basil indigenous to Pakistan. GC–MS analysis of the essential oil revealed the presence of 59 compounds that constituted 98.6% of the essential oil. OB essential oil (OB-EO) exhibited excellent an…

Acaricidal & anthelmintic efficacy of Ocimum basilicum essential oil & its major constituents estragole & linalool, with insights on acetylcholinesterase inhibition, Vet Parasitol, 309:109743.2022--Abstract: The present study evaluated the acaricidal & anthelmintic action of Ocimum basilicum essential oil (AP) & its main components against ticks & helminth parasites as well as to relate these activities to acetylcholinesterase inhibition. The in vitro acaricidal activity against Hyalomma scupense was evaluated by Adult Immersion Test (AIT) & Larval Packet Test (LPT), while the in vivo nemat…

Vasorelaxant & anti-platelet aggregation effects of aqueous Ocimum basilicum extract, J of Ethnopharmacol, 125(1):157-62, 2009-Abstract: In this work the endothelium-dependant vasorelaxant and anti-platelet aggregation activities of an aqueous extract from Ocimum basilicum were studied. Materials & methods: The vasorelaxant effect was undertaken in thoracic aorta from three experimental groups of rats: one of them (NCG) fed with standard diet, the second (HCG) with hypercholesterolemic diet (HCD) & the third (BTG) with hypercholesterolemic diet together with an intragastric administration o…

Anti-Cryptococcal activity of ethanol crude extract & hexane fraction from Ocimum basilicum var. Maria Bonita: mechanisms of action & synergism with amphotericin B & Ocimum basilicum essential oil. Pharm Biol. 2017; 55(1):1380-8.-Abstract: This study evaluates the anti-Cryptococcal activity of ethanol crude extract & hexane fraction obtained from O. basilicum var. Maria Bonita leaves. MATERIALS & METHODS: The MIC values for Cryptococcus sp. were obtained according to Clinical & Laboratory Standards Institute in a range of 0.3-2500 μg/mL. The checkerboard assay evaluated the association of t…

Chemomodulatory efficacy of basil leaf (Ocimum basilicum) on drug metabolizing & antioxidant enzymes, & on carcinogen-induced skin & forestomach papillomagenesis. Phytomed. 2004; 11(2-3):139-51-Abstract: Basil or sweet basil (Ocimum basilicum) is cultivated throughout India & is known for its medicinal value. The effects of doses of 200 & 400 mg/kg body weight of hydroalcoholic extract (80% ethanol, 20% water) of the fresh leaves of O basilicum on xenobiotic metabolizing Phase I & Phase II enzymes, antioxidant enzymes, Glutathione content, Lactate dehydrogenase & lipid peroxidation in the l…

Antioxidant Activity of Coleus Blumei, Orthosiphon Stamineus, Ocimum basilicum & Mentha arvensis from Lamiaceae Family, Inter J of Nat & Engine Sci, 2 (1): 93-95, 2008-Abstract: groups of Lamiaceae plants namely Coleus blumei, Orthosiphon stamineus, Ocimum basilicum & Mentha arvensis were collected from Penang, Malaysia was screened for their in vitro antioxidant activity. Stems & leaves of selected plants were dried at 45 °C & powdered. Then, extraction was performed with methanol. By employing DPPH (2,2-diphenyl-1-picrylhydrazyl radical) scavenging assays, it was shown that all the methan…

Low-temperature Extracts of Purple Blossoms of Basil (Ocimum Basilicum L.) Intervened Mitochondrial Translocation Contributes Prompted Apoptosis in Human Breast Cancer Cells. Biol. Res. 54, 2. 10.118, 2021-Abstract: This study aimed to validate the impact of dark purple blossoms of Ocimum basilicum aqueous extract at low temperature (0 °C) mediated mitochondrial fission contributed to induced apoptosis in human breast cancer cells. Methods: Fresh blossoms were extracted at low temperature (0 °C) using a watery solvent. Human MCF7 breast cancer cells were then treated with 3 separate fluctua…

Major Compounds from Ocimum basilicum L. & their Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus, Biomed J Sci & Tech Res, 2018; 33-Abstract: Sweet Basil (Ocimum basilicum Linn.) has a variety of therapeutic properties, including antimicrobial activity. This study aimed to determine the antibacterial activity of the major chemical components in the crude extract against methicillin resistant Staphylococcus aureus (MRSA) isolated from the clinical specimens. TLC & column chromatography resulted in the separation of two major compounds. On the basis of the spectral …

Effect of some plant extracts from Egyptian herbal plants against Toxoplasma gondii tachyzoites in vitro, Jl Vet Med Sci, 83(1) :100-7, 2021-Abstract: This study was aimed to explore the efficacy of several Egyptian plant extracts against Toxoplasma gondii infection in vitro for future development of a new, safe & effective compound for T. gondii. Methanol extracts from Matricaria chamomilla (German chamomile), Laurus nobilis, Citrullus colocynthis, Cinnamum camphora, Boswellia scara, & Melissa officinalis plants & oil extracts (either essential or fixed oils) of some plants such as: lemon …

STUDY THE ANALGESIC & SEDATIVE EFFECT OF Ocimum basilicum ALCOHOLIC EXTRACT IN MALE RATS. Diyala Agric Sci J, 2014; 6(1): 9-22-Abstract: This study was carried out on male rats to evaluate the analgesic & sedative effect of different doses of Alcoholic Extract of Ocimum basilicum leaves. The analgesic effect studied by using formalin test, 20 male rats divided to four groups (5 each), first group exposed water orally only before injection of formalin, second group exposed orally with Diclofenac at a dose 0.71mg/kgb. wt before injection of formalin, Third & fourth groups orally incubated wit…

GC/MS Study of Phytocompounds from The Leaves of Sweet Basil, EC (ECronicon) Pharmaceut Sci, 2.2: 265-77, 2016,

Atherogenicity of diabetic rats administered single & Combinatorial herbal extracts, Bulletin of Faculty of Pharmacy, Cairo University, 56: 2, 2016.-Abstract : Clarithromycin is a semi synthetic macrolide antibiotic that is proved to be extremely effective mono therapy in treating H. pylori infection. One of the various reasons reported for partial eradication of H. pylori infection is that the short dwelling time of antimicrobial agents in the stomach. Hence the principal object of the present work was to design & develop floating & swellable gastro retentive tablet of Clarithromycin to ob…

Toxicity of Ocimum basilicum L. leaf extract against Spodoptera exigua Hübner (Lepidoptera: Noctuidae), Plant Sci Today, 2024-Abstract: The growing awareness of sustainable agriculture encourages the search for natural alternatives to synthetic pesticides that promote resistance & contaminate the environment. Therefore, this study aims to evaluate the efficacy of basil (Ocimum basilicum L) leaf extract against the 2nd & 3rd instar larvae of S. exigua. The extracts were prepared using maceration & hydrodistillation & the pathogenicity was carried out against the 2nd & 3rd instar of S. exigua…

Antifibrotic effect of Ocimum basilicum L. & linalool on arecoline-induced fibrosis in human buccal fibroblasts: An in vitro study, J of Trans Res in Oral Oncology, 3(1):9, 2018.-Abstract: To explore Ocimum basilicum (sweet basil) & linalool for their antifibrotic activity in an arecoline-induced in vitro fibrotic model. Methods: Leaf extract of O. basilicum L. (LEOB) & linalool were used as experimental agents to test their antifibrogenic activity in vitro. Half-maximal inhibitory concentration (IC50) for arecoline, ethanolic LEOB, & linalool was determined using the 3-(4, 5-dimethylthiazo…

Chemical composition & bioactivity of essential oils & Ethanolic extracts of Ocimum basilicum L. & Thymus algeriensis Boiss. & Reut from the Algerian Saharan Atlas, BMC, Comp & Alter Med, 19 :146, 2019.-Abstract: The present study investigates the chemical composition & antioxidant, antimicrobial & anticancer activities of ethanolic extracts (EEs) & essential oils (EOs) from two species in the Lamiaceae family, Ocimum basilicum L. & Thymus algeriensis Boiss. & Reut cultivated in the Algerian Saharan Atlas. Methods: The total flavonoid contents of the plants’ ethanolic extracts were determin…

Antiepileptic activity of hydroalcoholic extract of basil in mice, J Herbmed Pharmacol., 2014; 3(1): 57-60-Abstract: To achieve an effective antiepileptic drug with few side effects, the antiepileptic effect of O. basilicum was investigated in Pentylenetetrazole (PTZ)-induced epilepsy model. Methods: In this experimental research, 48 laboratory female mice (for removing gender factor) were designated in 6 equal groups. The experimental groups comprised control, sham, & four treatment groups receiving the extract at 100, 250, 300, & 350 mg/kg doses (intraperitoneally; ip), 65 minutes before…

Topical anti-inflammatory effects of Ocimum basilicum leaf extract in the phorbol-12,13-dibutyrate Model of Mouse ear Inflammation, Planta Med, 75, 2009.-Abstract: Indian basil (Ocimum basilicum L. Family Lamiaceae) is a well-known traditional medicinal plant in the Indian sub-continent. The wound healing activity of the leaves has been reported in our earlier work [1]. In search of possible mode of action for wound healing activity, the topical anti-inflammatory property of the ethanol-water (25%) extract of leaves in mice has been carried out. Swiss albino mice of 22–25g of weight were us…

Potential therapeutic phytochemicals from Ocimum basilicum for the prevention & management of neurodegenerative diseases, 14th Meeting of the Asian-Pacific Soc for Neurochem, 2016-Abstract: Ocimum basilicum Linn., also known as sweet basil, is a member of the Lamiaceae family. It is used in traditional medicine to treat several ailments principally of the digestive & interestingly of the nervous system possibly due to its antioxidant properties. The neuroprotective properties of this plant have not been extensively studied which warrants for further investigation of its putative effect. In …

Supercritical fluid extraction as an alternative process to obtain essential oils with anti-inflammatory properties from Marjoram & sweet Basil. Ind Crop Prod. 2015; 67:121–9.-Abstract: The anti-inflammatory potential of marjoram & sweet basil essential oils obtained by supercritical fluid extraction (SFE) was tested in vitro using THP-1 human macrophage cells. THP-1 cells were activated by lipopolysaccharide or human ox-LDL & the cytokine secretion & gene expression of, respectively, TNF-α, IL-1β, IL-6 and IL-10 along with COX-2 & NFκB gene expression was evaluated. Results indicated that …

Chemistry & bioactivities of essential oils of some Ocimum species: an overview, Asian Pac J of Trop Biomed, 4(9):682-94, 2014-Abstract: Essential oils of different species of the genus Ocimum are natural flavouring materials of commercial importance. The data given in current literature are pertaining to the chemical composition of essential oils of different Ocimum species viz., Ocimum basilicum Linn. (alt. O basilicum var. minimum, O basilicum var. purpurience), Ocimum campechianum Mill., Ocimum canum Sims. (Ocimum americanum), Ocimum citriodorum, Ocimum gratissimum Linn., Ocimum kiliman…

Chemical characterization of Basil (Ocimum spp.) found in the markets & used in traditional medicine in Brazil, Econ Bot, 54 :207-216, 2000.

Role of Ocimum basilicum L. in prevention of ischemia & reperfusion-induced cerebral damage & motor dysfunctions in mice brain. J Ethnopharmacol. 2011; 137(3):1360-5. -Abstract: The genus Ocimum (Lamiaceae) has a long history of use as culinary and medicinal herbs. Many species are used for their antioxidant & neuroprotective activity in various parts of the world. Ocimum basilicum Linn has been used traditionally for the treatment of anxiety, diabetes, cardiovascular diseases, headaches, nerve pain, as anticonvulsant & anti-inflammatory & used in a variety of neurodegenerative disorders. A…

Ocimum basilicum ethanolic extract decreases cholesterol synthesis & lipid accumulation in human macrophages. Fitoterapia. 2008; 79 (7-8):515-23-Abstract: Previous work showed that Ocimum basilicum extract, used as Hypocholesterolemic agent by traditional medicine in Morocco, has hypolipidemic activity in rat acute hyperlipidemia. This study investigated the effects of ethanolic extract of O. basilicum on lipid accumulation in human macrophages. As modification of LDL increase atherogenicity of the particles we evaluated the effects of the extract on LDL oxidation. The extract caused a dose…

PHYTOCHEMICAL ANALYSIS & MINERAL ELEMENTS COMPOSITION OF OCIMUM BASILICUM OBTAINED IN JOS METROPOLIS, PLATEAU STATE, NIGERIA, Inter J of Engine & Technol, 2011; 11(06):161-5,

Synergistic antibacterial effect of honey & Herba Ocimi Basilici against some bacterial pathogen, J of Trad Chi M, 2013-Abstract: to evaluate the antibacterial activity of the combination of different honey brands & methanolic fraction of Herba Ocimi Basilici using agar well diffusion assay. METHODS: The antibacterial activity was deter- mined against thirteen pathogenic bacterial clinical isolates including six gram negative (Klebsiella pneumonia, Pseudomonas aeruginosa, Escherichia coli, Salmonella typhi, Salmonella typhimurium, Xanthomonas campestris) & six-gram positive strains (Entero…

Identification of volatile components in Basil (Ocimum basilicum-L) & Thyme leaves (Thymus vulgaris-L) & their Antioxidant properties, Food Chem, 91 :131-7, 2005.-Abstract: Aroma compounds in the extracts of basil leaves (Ocimum basilicum L.) & thyme leaves (Thymus vulgaris L.) were identified by gas chromatography (GC) & gas chromatography/mass spectrometry (GC/MS). The major aroma constituents of basil were 3, 7-dimethyl-1, 6-octadien-3-ol (linalool; 3.94 mg/g), 1-methoxy-4-(2-propenyl) benzene (estragole; 2.03 mg/g), methyl cinnamate (1.28 mg/g), 4-allyl-2-methoxyphenol (eugenol; 0.896 m…

enhancing antidiabetic & antimicrobial performance of Ocimum basilicum & Ocimum sanctum (L.) using silver Nanoparticles, Saudi J of Biol Sci, 24(6) :1294-305, 2017.-Abstract: The role of silver nanoparticles (AgNPs) is an attractive proposition for advancing modern diabetes therapies & applied science. Stable AgNPs with a size range of 3–25 nm was synthesized using aqueous leaf extracts from Ocimum basilicum, Ocimum sanctum & in combination. The concentration of the extracts facilitated the reduction of silver nitrate that led to the rapid formation of AgNPs at room temperature, indicating …

Synergistic Effects of Alcoholic Extract of Sweet Basil (Ocimum basilicum L) Leaves & Honey on Cutaneous Wound Healing in Rats, Int J of Mole Med & Adv Sci, 1(3):220-4,2005,

Potential Anti-inflammatory Properties of Crude Alcoholic Extract of O basilicum L. in Human Peripheral Blood Mononuclear Cells, J of Health Sci, 2007; 53(4):500-5,

Anti-proliferative activity of essential oil extracted from Thaï medicinal plants on KB & P388 cell lines, Cancer letters, 235 :114-20, 2006.-Abstract: Anti-proliferative activity of essential oil from 17 Thaï medicinal plants on human mouth epidermal carcinoma (KB) & murine leukemia (P388) cell lines using MTT assay were investigated. An amount of 1!104 cells/well of KB cell line & 1! 105 cells/well of P388 cell line were treated with the oil samples at different concentrations ranging from 0.019 to 4.962 mg/ml. In KB cell line, Guava (Psidium guajava L.) leaf oil showed the highest anti-p…

Effects of Sweet Basil Leaves (Ocimum Basilicum L) Addition on the Chemical, Antioxidant, & Storage Stability of roselle Calyces (Hibiscus sabdariffa) Drink. Food Chem. 371, 131170. 10.1016/j.foodchem.2021.131170, 2022-Abstract: . A drink made with roselle calyces (Hibiscus sabdariffa) & sweet basil leaves (Ocimum basilicum L) may provide therapeutic or preventive effects against chronic & infectious diseases. Damage caused by oxidative stress may be alleviated by the polyphenols found in roselle calyces & sweet basil leaves. The roselle-basil samples at different blend ratio were analysed …

Antiviral activities of extracts & selected pure constituents of Ocimum basilicum Exp Pharmacol Physiol, 2005; 32(10):811-6-Abstract: In the present study, extracts & purified components of Ocimum Basilicum were used to identify possible antiviral activities against DNA viruses (herpes viruses (HSV), adenoviruses (ADV) & hepatitis B virus) a& RNA viruses (coxsackievirus B1 (CVB1) & enterovirus 71 (EV71)). The results show that crude aqueous & ethanolic extracts of OB & selected purified components, namely apigenin, linalool & ursolic acid, exhibit a broad spectrum of antiviral activity. Of …

Antimicrobial Effects of Ocimum basilicum (Labiatae) Extract, Turk J Biol, 2005; 29:155-60,

A cytotoxic C-glycosylated derivative of apigenin from the leaves of Ocimum basilicum var. thyrsiflorum Rev Bras de Farmacognosia, 26(6) :763-6, 2016.-Abstract: The standardized 80% ethanolic extract of the leaves of Ocimum basilicum var. thyrsiflorum (L.) Benth., Lamiaceae, growing in KSA, exhibited a significant antioxidant activity compared to the ethyl acetate & butanol extracts, which was correlated to its higher phenolic & flavonoid contents. Chromatographic separation of the 80% ethanol extract resulted in the isolation of ten known compounds; cinnamic acid, gallic acid, methyl galla…

Effect of Ocimum basilicum, Ocimum selloi & Rosmarinic Acid on Cerebral Vascular Damage in a Chronic Hypertension Model. Biol Pharm Bull. 2019; 42 (2):201-211.-Abstract: The main objective of treatment against hypertension is not only to reduce blood pressure levels, but also to reduce vascular risk in general. In the present work, administering angiotensin II (AGII; 0.2 µg/kg intraperitoneally (i.p.) for 12 weeks) activates the hypothalamic-pituitary-adrenal (HPA) axis, which caused an increase in corticosterone levels, as well as in proinflammatory cytokines (interleukin 1β (IL-1β), inter…

Mosquito larvicidal activity of Ocimum basilicum Linn. India J Med Res. 1982; 75:220–2.

Volatile compounds of Lamiaceae exhibit a synergistic antibacterial activity with Streptomycin, Braz J of Microbiol, 45(4) :134-7, 2014.-Abstract: In the present work, we identified the volatile compounds of ethanol extracts of Melissa officinalis, Mentha sp. Ocimum basilicum, Plectranthus barbatus & Rosmarinus officinalis by gas chromatography/mass spectrometry (GC/MS). Also was evaluated antimicrobial activity of ethanol extracts against 6 bacteria of clinical interest & was tested the interaction of these extracts with a commercial antibiotic Streptomycin. Phytol was a compound identifie…

Evaluation of the gastric Antiulcerogenic effects of Solanum nigrum, Brassica oleracea & Ocimum basilicum in rats, J Ethnopharmacol, 27 :163-176, 1989.

Anti-inflammatory, immunomodulatory & anti-oxidant effects of Ocimum basilicum L. & Its main constituents: A review Iran J basic Med Sci, 26:(6):617-2023-Abstract: Ocimum basilicum L. (O. basilicum) is an ornamental and therapeutic plant with various pharmacological effects & medical applications. In this article, detailed information on the anti-oxidant, immunomodulatory, and anti-inflammatory properties of O. basilicum & its main constituents were provided. The literature survey of the different databases until the end of November 2021 was explored on the immunomodulatory, anti-inflammatory…

Ocimum basilicum: Antibacterial activity & association study with antibiotics against bacteria of clinical importance, Pharmaceut Biol, 2016; 54(5): 863-7.

PHYTOCHEMICAL & PHARMACOLOGICAL STUDIES ON OCIMUM BASILICUM LINN - A REVIEW, Inter J Chem Res R, 2012; 4(23),

Phytochemical Profile & Evaluation of the Biological Activities of Essential Oils Derived from the Greek Aromatic Plant Species Ocimum basilicum, Mentha spicata, Pimpinella anisum & Fortunella margarita. Molecules. 21(8). Pii: E1069. 2016-Abstract: In the present study, we analyzed the composition of the volatile preparations of essential oils of the Greek plants Ocimum basilicum (sweet basil), Mentha spicata (spearmint), Pimpinella anisum (anise) & Fortunella margarita (kumquat). GC/MS analyses revealed that the major components in the essential oil fractions, were carvone (85.4%) in spear…

The neuroprotective attribution of Ocimum basilicum: a review on the prevention & management of neurodegenerative disorders. Future J of Pharmaceut Sci, 2021,

Central properties & chemical composition of Ocimum basilicum essential oil, Pharmaceut Biol, 44(8) :619-626, 2008-Abstract: In the current study, the aerial part of Ocimum basilicum was used, & its essential oil was obtained by hydrodistillation. The essential oil of OB was screened for its composition & some CNS activities (viz. sedative, hypnotic, anticonvulsant, local anesthetic). When tested in mice, OB essential oil had no effect on motor activity up to a dose of 1.2 mL kg at 90 min post-administration. However, higher doses produced motor impairment at all time intervals. Pentobarbit…

Wound healing potential of Ocimum sanctum Linn. with induction of tumor necrosis factor-α Indian J of Experiment Biol, 48:402-06, 2010-Abstract: Wound healing activity of cold aqueous extract of O. sanctum leaves along with its effect on tumor necrosis factor-α (TNF-α) was assessed using excision model of wound repair in Wistar albino rats. After application of the OS extract, rate of epithelization with an increase in wound contraction was observed. In animals, treated with 10% OS extract in petroleum jelly, wound healing was faster as compared to control group which were treated with petr…

Hypnotic Effect of Ocimum basilicum on Pentobarbital-Induced Sleep in Mice. Iran Red Crescent Med J. 2016, 18(7):e24261-doi: 10.5812/ircmj.24261.

Synergism Effect of the Essential Oil from Ocimum basilicum var. Maria Bonita & Its Major Components with Fluconazole & Its Influence on Ergosterol Biosynthesis. Evid Based Comp Alter Med. 2016; 5647182.-Abstract: The aim of this study was to evaluate the activity of the EO & its major components of Ocimum basilicum var. Maria Bonita, a genetically improved cultivar, against the fluconazole sensitive & resistant strains of Candida albicans & Cryptococcus neoformans. Geraniol presented better results than the EO, with a low MIC (76 μg/mL against C. neoformans & 152 μg/mL against both Candida…

Evaluation of the antioxidant activity of Ocimum sp. J. Food Technol., 4: 318-321, 2006.

Phytochemical Analysis & In Vitro Cytotoxic Activity against Colorectal Adenocarcinoma Cells of Hippophae rhamnoides L., Cymbopogon citratus (D.C.) Stapf, & Ocimum basilicum L. Essential Oils, Plants (Basel): 10(12):, 2021-Abstract: Essential oils (EOs) contain valuable compounds, with antibacterial, anti-inflammatory, & anticancer properties, which might serve as effective solutions in CRC prophylaxis or treatment. The aim of the present work was to evaluate the phytochemical composition & in vitro biological activity of essential oils derived from Hippophae rhamnoides (Hr_EO), Cymbopogon …

Evaluation of basil extract (Ocimum basilicum L.) on oxidative, anti-genotoxic & anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents, Braz. J. Pharm. Sci., 2017; 53(1)-Abstract: Ocimum is one of the most important genera of the Lamiaceae family. Several studies about basil & its popular use reveal many characteristics of the herb, including its use as antioxidant, antiaging, anti-inflammatory, anticarcinogenic, antimicrobial & cardiovascular agents, among others. In this paper, we evaluated genotoxic, oxidative & anti-inflammatory parameters from the ex…

Chemical composition of Ocimum basilicum L. essential oil from different regions in the Kingdom of Saudi Arabia by using Gas chromatography mass spectrometer, J of Med Plants Studies; 2018; 6(1):14-9,

Structural Analysis & Biological Toxicity of Aflatoxins B1 & B2 Degradation Products Following Detoxification by Ocimum basilicum & Cassia fistula Aqueous Extracts, Front. Microbiol.2016-Abstract: This study showed the comparison between Ocimum basilicum & Cassia fistula (leaves & branch) aqueous extracts for their ability to detoxify of aflatoxins B1 and B2 (AFB1; 100 μg L-1 and AFB2; 50 μg L-1) by In Vitro assays & decontamination studies. Results indicated that O. basilicum leaves extract was found to be highly significant (P < 0.05) in degrading AFB1 & AFB2, i.e., 90.4 & 88.6%, respecti…

Phenolics Composition & Antioxidant Activity of Sweet Basil (Ocimum basilicum L.). J of Agric & Food Chem, 2003, 51 (15) , 4442-9-Abstract : The antioxidant activity of a methanolic extract of Ocimum basilicum L. (sweet basil) was examined using different in vitro assay model systems. The crude extract was fractionated on a Sephadex LH-20 column, & six fractions were identified. The DPPH scavenging assay system and the oxidation of the soy phosphatidylcholine liposome model system were used to evaluate the antioxidant activity of each fraction. Fraction IV showed the strongest activity foll…

Prevention of Ethanol-induced Gastric Mucosal Injury by Ocimum basilicum Seed Extract in Rats, ASM Sci J, 1 (1): 1-6. ISSN 1823-6782, 2007,

Investigation of the Antifungal Activity & Mode of Action of Thymus vulgaris, Citrus Limonum, Pelargonium graveolens, Cinnamomum cassia, Ocimum basilicum, & Eugenia Caryophyllus Essential Oils, Mol, 8;23(5):1116. 2018-Abstract: the antimicrobial activity of plant oils & extracts has been recognized for many years. In this study the activity of Thymus vulgaris, Citrus Limonum, Pelargonium graveolens, Cinnamomum cassia, Ocimum basilicum, & Eugenia Caryophyllus essential oils (EOs) distributed by Pollen Aroma (Nowy Dwór Mazowiecki, Poland) was investigated against a group of 183 clinical isola…

Preliminary antihyperglycemic activity-guided studies on the leaf extract & fractions of Ocimum basilicum L. J. Chem. Pharm. Res., 2014, 6(4): 575-80,

Neuroprotective Effects of Ocimum basilicum Extract against Hydrogen Peroxide-Induced Oxidative Stress in SK-N-SH Neuroblastoma Cells, Sains Malaysiana, 47(9):2129-39, 2018-Abstract: In the present study, the neuroprotective effects of Ocimum basilicum var. thyrisiflora against hydrogen peroxide (H2O2)-induced oxidative stress in SK-N-SH neuroblastoma cells were evaluated. The exposure of SK-N-SH cells to 50 µM H2O2 for 24 h induced cytotoxicity and apoptosis as measured by cell viability and flow cytometry, respectively. Pretreatment with ethyl acetate (ObEA) fraction at 3.1-25 µg/mL show…

Cytotoxic & immunomodulatory properties of Tinospora cordifolia, Boerhaavia diffusa, Berberis aristata, & Ocimum basilicum extracts against HPV-positive cervical cancer cell line, BMC Comp Med Ther, 25(1):59. 2025-Abstract: Cervical cancer remains a significant public health concern, especially for low-and middle-income countries. This study explores the dual potential of medicinal plant extracts as both anticancer agents & immunomodulators, particularly in HPV-positive cervical cancer, while also addressing the limitations of conventional chemotherapy. Methods: Extracts from Tinospora cord…

Fumigant Toxicity of Essential Oils from Basil & Spearmint Against Two Major Pyralid Pests of Stored Products, J Economy Entomol, 108(2):805-10, 2015-Abstract: The fumigant activity of essential oil vapors distilled from sweet basil Ocimum basilicum L. & spearmint Mentha spicata L. (Lamiaceae) were tested against two major stored products pests Ephestia kuehniella (Zeller) & Plodia interpunctella (Hübner) (Lepidoptera: Pyralidae). Various oil doses (0.5, 2.5, 5, 50, 250, 500, 1,000, & 1,500 µl/liter air), for an exposure period of 24 h, were tested. The EOs were subjected to gas chromatogra…

Aroma Content of Fresh Basil (Ocimum basilicum L.) Leaves Is Affected by Light Reflected from Colored Mulches, J. Agric. Food Chem., 51:2272−6, 2003,

Ocimum basilicum & Lagenaria siceraria Loaded Lignin Nanoparticles as Versatile Antioxidant, Immune Modulatory, Anti-Efflux, & Antimicrobial Agents for Combating Multidrug-Resistant Bacteria & Fungi, Antioxidants (Basel), 19;13(7):865, 2024--Abstract: Lignin nanoparticles emerged as a promising alternative for drug delivery systems owing to their biodegradability & bioactive properties. This study investigated the antimicrobial activity of the ethanolic extract of Ocimum basilicum-loaded lignin nanoparticles (OB-LNPs) & Lagenaria siceraria seed oil-loaded lignin nanoparticles (LS-LNPs) to f…

In vitro antiplasmodial effect of ethanolic extracts of traditional medicinal plant Ocimum species against Plasmodium falciparum, Asian Pac JL of Trop Med, 5(2):103-6, 2012-Abstract: To identify the possible antiplasmodial compounds from leaf, stem, root & flower extracts of Ocimum canum (O. canum), Ocimum sanctum (O. sanctum) & Ocimum basilicum (O. basilicum). Methods: The O. canum, O. sanctum & O. basilicum were collected from Ramanathapuram District, Tamil Nadu & the extraction was carried out in ethanol. The filter sterilized extracts (100, 50, 25, 12.5, 6.25 & 3.125 μg/mL) of leaf, ste…

Chemical composition & antimicrobial activity of the essential oil of Ocimum basilicum L. (sweet basil) from Western Ghats of North West Karnataka, India, Anc Sci Life, 2014; 33(3): 151–6-doi: 10.4103/0257-7941.144618,

A comparative – in-vitro study of anticancer effect of Mentha Piperata, Ocimum basilicum & Coleus aromaticus against human laryngeal epidermoid carcinoma (HEP-2) cell lines, J of Med Plants Studies, 2(1):06-99, 2014.-Abstract: Aromatic plants of Lamiaceae family are known for its traditional medicine. The leaves of the plants are promoted in relieving sore throats, toothaches, colds, coughs, laryngitits, bronchitis, nasal congestion & inflammation of the mouth & throat. Ethanolic extracts of Mentha Piperata, Ocimum basilicum & Coleus aromaticus were studied for the in-vitro cytotoxicity aga…

Aqueous extracts of Ocimum basilicum L. (sweet basil) decrease platelet aggregation induced by ADP & thrombin in vitro and rats arterio–venous shunt thrombosis in vivo, Thrombosis Res, 2006; 118(6): 733-9-DOI: https://doi.org/10.1016/j.thromres.2005.12.011,

In Vitro Assessment of the Interaction Potential of Ocimum basilicum (L.) Extracts on CYP2B6, 3A4, & Rifampicin Metabolism, Front Pharmacol, 11:517, 2020-Abstract: Ocimum basilicum is a common culinary herb, used as a traditional medicine for various medical conditions including HIV/AIDS & tuberculosis, in Africa. The objective of this study was to evaluate the effect of methanol, ethanol, aqueous & ethyl acetate extracts of the dried leaves & inflorescence of OB, on the activity of cytochrome P450 enzymes (CYPs) CYP2B6 & 3A4, as well as esterase-mediated metabolism of rifampicin to 25-O-de…

Estimation of total polyphenols contents in Ocimum basilicum L Origanum vulgare L & Thymus vulgaris L-commercial samples. Herba Polonica 55(1):35-42, 2009.

Produce an Antihyperalgesic Effect in Animal Models for Fibromyalgia, Int J of Mol Sci, 16(1):547-63, 2015-Abstract: Ocimum basilicum leaves produce essential oils (LEO) rich in monoterpenes. The short half-life & water insolubility are limitations for LEO medical uses. β-Cyclodextrin (β-CD) has been employed to improve the pharmacological properties of LEO. We assessed the antihyperalgesic profile of LEO, isolated or complexed in β-CD (LEO/β-CD), on an animal model for fibromyalgia. Behavioral tests: mice were treated every day with either LEO/β-CD (25, 50 or 100 mg/kg, p.o.), LEO (25 mg/k…

The Effects of Ocimum Basilicum Ethanol Extract on Carrageenan Induced Paw Inflammation in Rats, Pharmaceut Sci, 2015, 20, 149-56-Abstract: here, the effect of O. basilicum ethanol extract was evaluated on carrageenan induced paw edema in male Wistar rats. Methods: OB ethanol extract was achieved through maceration procedure. Next, the paw inflammation was induced with 1% carrageenan, subcutaneous, to all groups after 1h of the intraperitoneal injection of OB extracts (0, 2.5, 5 & 10mg/kg; respectively). The paw thickness was measured at hourly intervals for 4h. Finally, histological examin…

The Egg Hatchability & The Development of Aedes aegypti Mosquitoes in Ethanol Extracts of The Leaves of Bitter Melon (Momordica charantia L.) & Basil (Ocimum basilicum L.) IOP Conf Series: Earth & Environment Sci, 2019-Abstract: The botanical insecticides acquired from the ethanol extracts of the leaves of Bitter Melon (Momordica charantia L.) & Basil (Ocimum basilicum L.) has been conducted on dengue fever mosquitoes’ vector of Aedes aegypti by observing the parameters; hatchability of eggs-larvae, the development of larvae-pupae, & pupae-adult using a complete randomized design (CRD) fact…

Optimisation study of gum extraction from Basil seeds (Ocimum basilicum L.), Inter J of Food Sci &Technol, 2009, 44, 1755–62,

Antimicrobial Activity of Basil (Ocimum basilicum) Oil against Salmonella Enteritidis in Vitro & in Food, BioSci Biotechnol & Biochem, 74:06, 2010.-Abstract: Nine essential oils were examined for antimicrobial activity against reference & clinical strains of Salmonella Enteritidis. Based on the size of the inhibition zone & the minimal inhibitory concentration, basil oil had the strongest antimicrobial activity against all the tested bacteria & S. Enteritidis SE3 was the most sensitive strain to all the tested oils. Gas chromatography/mass spectrometry analysis revealed that the major const…

Phytochemical characterization, antioxidant activity & antihypertensive evaluation of Ocimum basilicum L. in l-NAME induced hypertensive rats & its correlation analysis, Helyon, 9(4):e-14644, 2023-Abstract: Ocimum basilicum Linn. (basil) is an aromatic culinary herb that has shown a great potential in therapeutic world. It has many promising pharmacological activities that make it centre for investigations for many researchers. Current study has been planned to determine chemical constituents of basil leaves extracts & their in-vitro & ex-vivo antioxidant & in-vivo antihypertensive potenti…

Antibacterial activity of ethanolic extract of Sweet Basil (Ocimum basilicum L.) leaves against Escherichia coli in experimentally infected Rats, Kufa J for Vet Med Sci, (5) (2) 2014-Abstract: The present study was carried out to investigate the antibacterial activity of Ocimum basilicum (OB)ethanolic extract in-vivo by inducing diarrhea in rats which was caused by oral administration of pathogenic Escherichia coli. The experiment that performed in this present study included study in-vivo antibacterial activity of the extract after inducing infectious diarrhea with oral pathogenic E. coli …

Antibacterial & Antioxidant study of Ocimum basilicum Labiatae (sweet basil), J of Adv Pharm Educ & Res, 2: 104-112 (2011),

Ethanolic extracts from mint (Mentha arvensis) & basil (Ocimum basilicum) leaves: Antioxidant, antimicrobial capacities & shelf-life extension of refrigerated squid mantle cut, Int Aquat Res, 15:313-22, 2023-Abstract: This research aimed to investigate antioxidant & antimicrobial activities of mint leaf ethanolic extract & basil leaf ethanolic extracts. The extract with highest bioactivities further applied as a preservative on squid mantle cut (SMC) to extend the shelf-life during refrigerated storage. Mint and basil leaves ethanolic extracts denoted as mint leaf ethanolic extract (ME) & b…

IN VITRO ANTIOXIDANT ACTIVITIES OF OCIMUM SPECIES: OCIMUM BASILICUM & OCIMUM SANCTUM, Journal of Cell & Tissue Res, 201

Anti-herpes simplex virus activity of extracts from the culinary herbs Ocimum sanctum L., Ocimum basilicum L. & Ocimum americanum L. Afr. Jl Biotechnol.2011, 10, 860–6-Abstract: This study demonstrates anti-herpes simplex virus activity of dichloromethane & methanol extracts of Ocimum sanctum L., Ocimum basilicum L. & Ocimum americanum L. Green monkey kidney cells were protected from HSV-2 infection by the dichloromethane extract of O. americanum L. & the methanol extract of O. sanctum, with therapeutic indexes (TI) of 1.865 and 1.644, respectively, when the cells were treated before viral …

The potential effects of Ocimum basilicum on health: a review of pharmacological & toxicological studies, Expert Opin Drug Metab Toxicol. 2018, 14(7):679-92-Abstract: Basil (Ocimum basilicum L., OB) is a plant world widely used as a spice & a typical ingredient of the healthy Mediterranean diet. In traditional medicine, OB is indicated for many maladies & conditions; OB-containing nutritional supplements are increasingly sold. Conversely, safety concerns have been raised about the promutagens & procarcinogens alkenyl benzenes contained in OB. Areas covered: A critical review of the current …

Oral supplementation of Ocimum basilicum has the potential to improves the locomotory, exploratory, anxiolytic behavior & learning in adult male albino mice, Neurol Sci, 36:73–78, 2015-Abstract: The aim of this project was to determine the effect of 100 mg/ml solvent/kg body weight of Ocimum basilicum leaf extract on neuromuscular co-ordination, exploratory, locomotory & short-term memory formation in male albino mice. Five weeks old, male albino mice were used as the experimental animals in order to demonstrate the effect of O. basilicum’s extract on learning & memory. Each male albino mou…

Antihypertensive effects of Ocimum basilicum L. (OBL) on blood pressure in renovascular hypertensive rats, Hypertension Res, (2010) 33, 727-Abstract: Ocimum basilicum L. (OBL), sweet basil, is a medicinal herb used in traditional Chinese medicine to treat cardiovascular diseases including hypertension. The objective of the study was to investigate the possible antihypertensive effects of OBL extract in renovascular hypertensive rats. The two-kidney one-clip (2K1C) Goldblatt model of renovascular hypertension was used in Wistar rats. Rats were randomized into sham, untreated 2K1C, captopril-…

Comparative Study of Volatile Compounds from Genus Ocimum, Am J of Applied Sci, 6 (3): 523-8, 2009,

Anthocyanins in Basil (Ocimum basilicum L. J. Agric. Food Chem., 1998, 46 (5) :1734–8-DOI: 10.1021/jf970887r-Abstract: The Lamiaceae family, which includes basil, sage, & thyme, has long been recognized as a rich source of diverse & unique anthocyanins. The development of intensely purple pigmented basil in the ornamental and herb trade prompted this examination of eight commercial varieties of purple basils (Ocimum basilicum L.) as a potential new source of anthocyanins. Anthocyanins were isolated and characterized utilizing high-performance liquid chromatography, spectral data, and plasma…