Ocimum basilicum (Bazilik) : vertus médicinales en extraction alcoolique

Ocimum basilicum (Bazilik, Basilic, Basilic pourpre (var Thyrsiflorum), Basil, Purple basil (var. Thyrsiflorum)) — famille Lamiacées.

Synonymes scientifiques : Ocimum thyrsiflorum-(L)-Benth.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 26 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 119 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gbadegesin MA (2010)

     Extrait We evaluated the effects of aqueous & ethanolic leaf extracts of Ocimum basilicum on sodium arsenite-induced hepatotoxicity in Wistar rats. We observed that treatment of the animals with the extracts before or just after sodium arsenite administration significantly (p < 0.05) reduced mean liver & serum γ-Glutamyl transferase (γGT) & serum alkaline phosphatase (ALP) activities when compared with the group administered the toxin alone.

   • Selon Kumar S (2020)

     Extrait Ocimum basilicum is a common culinary herb, used as a traditional medicine for various medical conditions including HIV/AIDS & tuberculosis, in Africa. The putative gastrointestinal tract (GIT) concentration for all extracts was calculated as 2,400 μg/ml & hepatic circulation concentrations were estimated at 805.68 μg/ml for the aqueous extract, & 226.56 μg/ml for methanolic extract.

   • Selon Touiss I (2021)

     Extrait The RAE at 200 mg/kg body weight lowered significantly (p < 0.001) plasma enzyme activities of liver, which is designation of hepatoprotective action of extract. Our study suggests that RAE may be used as a hepatoprotective agent against toxic effects caused by CCl4 & other chemical agents in the liver,.

   • Selon El-Samahy LA (2024)

     Extrait This study investigated the antimicrobial activity of the ethanolic extract of Ocimum basilicum-loaded lignin nanoparticles (OB-LNPs) & Lagenaria siceraria seed oil-loaded lignin nanoparticles (LS-LNPs) to find a solution for antimicrobial resistance. Oral administration of OB-LNPs & LS-LNPs in combination with ciprofloxacin had a significant effect on all blood parameters, as well as on liver & kidney function parameters.

   • Selon Dasgupta T (2004)

     Extrait The effects of doses of 200 & 400 mg/kg body weight of hydroalcoholic extract (80% ethanol, 20% water) of the fresh leaves of O basilicum on xenobiotic metabolizing Phase I & Phase II enzymes, antioxidant enzymes, Glutathione content, Lactate dehydrogenase & lipid peroxidation in the liver of 8-9 weeks old Swiss albino mice were examined. Basil or sweet basil (Ocimum basilicum) is cultivated throughout India & is known for its medicinal value.

2. 2

   Diarrhée infectieuse causée par E coli

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2014)

     Extrait The present study was carried out to investigate the antibacterial activity of Ocimum basilicum (OB)ethanolic extract in-vivo by inducing diarrhea in rats which was caused by oral administration of pathogenic Escherichia coli. The experiment that performed in this present study included study in-vivo antibacterial activity of the extract after inducing infectious diarrhea with oral pathogenic E.

   • Selon Rezzoug M (2019)

     Extrait The present study investigates the chemical composition & antioxidant, antimicrobial & anticancer activities of ethanolic extracts (EEs) & essential oils (EOs) from two species in the Lamiaceae family, Ocimum basilicum L. Conclusion: The results suggest that the bioactive compounds found in the ethanolic extracts & essential oils from O basilicum & T algeriensis, with diverse antioxidant, antimicrobial & anticancer activities, may have beneficial applications in nutraceutical & pharmaceutical technologies.

   • Selon Francio AE (2025)

     Extrait We conclude that the EO of TR shows promising antifungal activity & is an environmentally safe alternative for controlling fungal diseases in vegetables. vulgaris & their antioxidant & antifungal activities against Alternaria alternata strains.

   • Selon Iram W (2016)

     Extrait This study showed the comparison between Ocimum basilicum & Cassia fistula (leaves & branch) aqueous extracts for their ability to detoxify of aflatoxins B1 and B2 (AFB1; 100 μg L-1 and AFB2; 50 μg L-1) by In Vitro assays & decontamination studies. basilicum leaves extract was found to be highly significant (P < 0.05) in degrading AFB1 & AFB2, i.e., 90.4 & 88.6%, respectively.

   • Selon Araújo SV (2016)

     Extrait Araújo SV et al, Ocimum basilicum: Antibacterial activity & association study with antibiotics against bacteria of clinical importance, Pharmaceut Biol, 2016; 54(5): 863-7.

3. 3

   Infection bacterienne et fongique : Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Staphylococcus aureus, Salmonella enterica

   Partie usitée : Feuille. Association synergique mentionnée : Lagenaria siceraria-huile fixe.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon El-Samahy LA (2024)

     Extrait OB-LNPs & LS-LNPs were tested for their antimicrobial potential against Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Staphylococcus aureus, Salmonella enterica, Trichophyton mentagrophytes, Trichophyton rubrum, & Microsporum canis. This study investigated the antimicrobial activity of the ethanolic extract of Ocimum basilicum-loaded lignin nanoparticles (OB-LNPs) & Lagenaria siceraria seed oil-loaded lignin nanoparticles (LS-LNPs) to find a solution for antimicrobial resistance.

   • Selon Francio AE (2025)

     Extrait We conclude that the EO of TR shows promising antifungal activity & is an environmentally safe alternative for controlling fungal diseases in vegetables. vulgaris & their antioxidant & antifungal activities against Alternaria alternata strains.

   • Selon Rezzoug M (2019)

     Extrait The present study investigates the chemical composition & antioxidant, antimicrobial & anticancer activities of ethanolic extracts (EEs) & essential oils (EOs) from two species in the Lamiaceae family, Ocimum basilicum L. Conclusion: The results suggest that the bioactive compounds found in the ethanolic extracts & essential oils from O basilicum & T algeriensis, with diverse antioxidant, antimicrobial & anticancer activities, may have beneficial applications in nutraceutical & pharmaceutical technologies.

   • Selon Iram W (2016)

     Extrait This study showed the comparison between Ocimum basilicum & Cassia fistula (leaves & branch) aqueous extracts for their ability to detoxify of aflatoxins B1 and B2 (AFB1; 100 μg L-1 and AFB2; 50 μg L-1) by In Vitro assays & decontamination studies. basilicum leaves extract was found to be highly significant (P < 0.05) in degrading AFB1 & AFB2, i.e., 90.4 & 88.6%, respectively.

   • Selon Araújo SV (2016)

     Extrait Araújo SV et al, Ocimum basilicum: Antibacterial activity & association study with antibiotics against bacteria of clinical importance, Pharmaceut Biol, 2016; 54(5): 863-7.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.