Piper betle (Pwèv) : propiedades medicinales en extracción alcohólica

Piper betle (Pwèv, pimienta, Poivre, Proof, Pepper) — familia Pipéracées.

Sinónimos científicos : Artanthe hexagyna Miq., Betela mastica Raf., Chavica auriculata Miq., C betle (L.) Miq., C chuvya Miq., C densa Miq., C siriboa Miq., Cubeba seriboa Miq., Piper betel Blanco, P rubroglandulosum Chaveer. & Mokkamul, P betlum (L.) St.-Lag..

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 30 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 153 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Diabetes mellitus tipo II

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Arambewela LSR (2005)

     Extrait This was tested in normoglycaemic & streptozotocin (STZ)-induced diabetic rats using oral administration of hot water extract (HWE) & cold ethanolic extract (CEE). Leaves of Piper betle (Piperaceae) possess several bioactivities & are used in traditional medicinal systems.

   • Selon Santhaikumari P (2003)

     Extrait To study the effect of oral administration of Piper betle leaf powder suspension on lipid peroxidation & antioxidants in streptozotocin (STZ) diabetic rats. betle (75 & 150 mg/kg body weight) for 30 days resulted in a significant reduction in plasma thiobarbituric acid reactive substances (TBARS), hydroperoxides, alpha-tocopherol & significant improvement in glutathione, superoxide dismutase, catalase & glutathione peroxidase in the liver & kidney of STZ diabetic rats when compared with untreated diabetic rats.

   • Selon Sujatha GH (2011)

     Extrait Sujatha GH et al, Piper betle Linn: As a Remedy for Diabetes Mellitus, Inter J Res A Pharm, 2(5) 1601-3. 2011- -Sungkatavat P et al, Piper betle extract & its application in bovine teat dipping solution inhibit & eliminate biofilms in bovine mastitis-inducing staphylococci, Vet World, 16(10):2135-42.

   • Selon Kumar N (2010)

     Extrait The leaf extract, fractions & purified compounds are found to play a role in oral hygiene, anti-diabetic, cardiovascular, anti-inflammatory/ immunomodulatory, anti-ulcer, hepato-protective & anti-infective, etc.

   • Selon Santhaikumari P (2006)

     Extrait Santhaikumari P et al, Antihyperglycemic activity of Piper betle leaf on streptozotocin-induced diabetic rats, J Med Food, evaluated the 2006 Spring; 9(1): 108-1-.

2. 2

   Cáncer: tratamiento adyuvante del melanoma

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shah GA (2018)

     Extrait After in vivo screening of crude extracts it was concluded that ethyl acetate extract contains some antitumor agents when applied against mice bearing melanoma & depicted significant reduction in tumor size. The present study was carried out to evaluate the anti melanoma activity of Piper betle L.

   • Selon Abrahim NN (2012)

     Extrait Piper betle is a medicinal plant with various biological activities. Due to the current interest in the potential effects of antioxidants from natural products in breast cancer treatment, we investigated the antioxidant activities of the leaves of PB & its inhibitory effect on the proliferation of the breast cancer cell line, MCF-7.

   • Selon Del Socorro MML (2014)

     Extrait In this study, the cytotoxic activity of the methanol, ethanol, & crude aqueous extracts of the plant Betel Vine Piper betle Linn. Hence, PB is found to be containing cytotoxic compounds but this result does not necessarily suggest complete toxicity of the plant because it may also suggest potential antitumor or anticancer activities.

   • Selon Banerjee D (2014)

     Extrait Results: Lung cancer cell line (A549) was tested against four PB leaf extracts ie; aqueous, methanolic, ethyl acetate & petroleum ether for their anti proliferative activity. Conclusions: From the present study it was concluded that the leaf extracts of PB have anti proliferative & chemo preventive potential & can be use for the treatment of various ailments including human lung cancer.

   • Selon Paranipe R (2013)

     Extrait Explored for their unique medicinal properties, the leaves of Piper betel, an evergreen perennial vine, are a reservoir of phenolics with antimutagenic, antitumor & antioxidant activities. Further, the HC containing F2 subfraction was found to be ~8-fold more potent than the F2 subfraction that contained CHV, in human prostate cancer PC-3 cells as evaluated by the 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyl tetrazolium bromide assay.

3. 3

   Artrosis, artritis, reumatismo, edema

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon MURUGESAN S (2020)

     Extrait Betelvine (Piper betle L.) leaves have long been used in Asian countries as a medicine to relieve pain & some metabolic diseases. Rheumatoid Arthritis is a chronic, inflammatory, and systemic autoimmune disease, it affects elders worldwide.

   • Selon Reddy PS (2016)

     Extrait The experimental models of tail-flick method & acetic acid induced writhing were used to study the analgesic activity whereas carrageenan induced paw edema and cotton pellet granuloma models were used for anti-inflammatory action. The analgesic & anti-inflammatory activity of P.betle may be attributed to the presence of various phyto constituents’ viz.

   • Selon MAZURA Pisar (s.d.)

     Extrait Further purification of this fraction revealed hydroxychavicol as the main component involved in its anti-inflammatory activity. Betel vine (Piper betle) is a tropical Asian plant belonging to the family Piperaceae.

   • Selon Kumar N (2010)

     Extrait The leaf extract, fractions & purified compounds are found to play a role in oral hygiene, anti-diabetic, cardiovascular, anti-inflammatory/ immunomodulatory, anti-ulcer, hepato-protective & anti-infective, etc. Patents were also awarded for some of the biological activities like anti-inflammatory, anti-cancer & immunomodulatory associated with leaf extracts&d purified compounds.

   • Selon Rintu D (s.d.)

     Extrait Rintu D et al, Anti-Oxidant and Anti-Inflammatory Activities of Different Varieties of Piper Leaf Extracts (Piper Betle L.), Nutr Food Sci 5:415.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.