Syzygium aromaticum (Klou-Jiwôf) : propiedades medicinales en extracción alcohólica
Syzygium aromaticum (Klou-Jiwôf, Clavo de olor, Clou-de-girofle, Clove) — familia Myrtacées.
Sinónimos científicos : Caryophyllus aromaticus L, Eugenia aromatica (L.) Baill, E caryophyllata Thunb, E Caryophyllus (Spreng.) Bullock & S.G. Harrison.
Fuentes externas reconocidas asociadas a esta monografía: TRAMIL y Farmacopea francesa.
Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 24 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 151 referencias científicas para esta especie (detalle completo en la aplicación).
Indicaciones terapéuticas en extracción alcohólica:
Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).
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Diabetes mellitus tipo II: similar a la glibenclamida
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon MANIKANDAN M et al (2026)
Extrait The present study investigates the anti-hyperglycemic & anti-hyperlipidemic effects of the ethanolic extract of Syzygium aromaticum (L.) Merr. The ETOH extract of SA & its key constituent eugenol demonstrated potent anti-hyperglycemic & anti-hyperlipidemic effects, suggesting their potential use as natural therapeutic agents for diabetes management.
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Selon RAWA MSA et al (2022)
Extrait The molecular mechanisms of Syzygium species in neuroprotection include the inhibition of AChE to correct cholinergic transmission, suppression of pro-inflammatory mediators, oxidative stress markers, RIS production, enhancement of antioxidant enzymes, the restoration of brain ions homeostasis, the inhibition of microglial invasion, the modulation of ß-cell insulin release, the enhancement of lipid accumulation, glucose uptake, & adiponectin secretion via the activation of the insulin signaling pathway. This review attempts to review the pharmacological importance of the Syzygium genus in neuroprotection, focusing on anti-cholinesterase, anti-diabetic, anti-inflammatory, & antioxidant properties.
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Selon Jhansi Lakshmi (2021)
Extrait Syzygium aromaticum (Clove), Syzygium samarangense (Java apple), S anisatum (Aniseed tree), Syzygium caryophyllatum (Lilly pilly), Syzygium aqueum (Water apple), Syzygium jambos (Mountain Apple), Syzygium cumini (Java plum), S australe (Brush cherry), Sluehmannii (Riberry) etc., were mentioned in this review article. Biological activities like anti-diabetic, antioxidant, anti-bacterial, anti-inflammatory, platelet inhibition, hepato- protective were found among plants of Syzygium species.
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Selon Andile K (2014)
Extrait Syzygium aromaticum-derived triterpenes modulate intestinal glucose handling in streptozotocin-induced diabetic rats; Thesis: Univ of Kwazulu-Natal, 2014,.
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Selon Chaudhry Z (2013)
Extrait Chaudhry Z et al, EFFECT OF SYZYGIUM AROMATICUM (CLOVE) EXTRACT ON BLOOD GLUCOSE LEVEL IN STREPTOZOTOCIN INDUCED DIABETIC RATS, Pak Armed Forces Med J, 63 :3, 2013,.
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Selon MANIKANDAN M et al (2026)
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Infección bacteriana: multirresistente (MRSA): Escherichia coli, Klebsiella pneumoniae y Candida albicans. Cepas ATCC de Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, Streptococcus bovis, Pseudomonas aeruginosa, Salmonella typhimurium, Escherichia coli y Klebsiella pneumoniae
Scientific references (short excerpts)
Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.
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Selon Khan R (2009)
Excerpt ATCC strains of Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, Streptococcus bovis, Pseudomonas aeruginosa, Salmonella typhimurium, Escherichia coli, Klebsiella pneumoniae & Candida albicans were also tested. Antimicrobial activities of the crude ethanolic extracts of five plants were screened against multidrug resistant (MDR) strains of Escherichia coli, Klebsiella pneumoniae & Candida albicans.
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Selon Agrawal MK et al (2016)
Excerpt Staphylococcus aureus (NCIM 2079), Bacillus subtilis (NCIM 2063), Escherichia coli (NCIM 2065), Salmonella typhimurium (NCIM 2501), Streptococcus pneumoniae (NCIM 5281) & a yeast Candida albicans (NCIM 3471). Ethanolic & aqueous extracts of 20 Indian medicinal plants traditionally used in medicine were studied for their antibacterial & anticandidal activity against five multi – drug resistant bacteria i.
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Selon Pinto E et al (2009)
Excerpt The composition and antifungal activity of clove essential oil (EO), obtained from Syzygium aromaticum, were studied. MICs, determined
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Excerpt according to Clinical and Laboratory Standards Institute protocols, and minimum fungicidal concentration were used to evaluate the antifungal activity of the clove oil and its main component, eugenol, against Candida, Aspergillus and dermatophyte clinical and American Type Culture Collection strains.
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Selon Yassin MT (2020)
Excerpt In the current study, the antibacterial efficiency of clove extracts (acetonic, dichloromethane, ethanolic, & petroleum ether) against four pathogenic bacterial strains [Escherichia coli, Salmonella typhi, Staphylococcus aureus & Methicillin-Resistant S aureus (MRSA)] was estimated by disc diffusion method. Results & conclusion: The dichloromethane extract presented the highest antibacterial potency against the pathogenic isolates recording minimum inhibitory concentration (MIC) of 1 mg/disc against MRSA strain & 0.5 mg/disc against both of E.
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Selon Mathkoor MM (2024)
Excerpt aureus), Pseudomonas aeruginosa (P aeruginosa), & Escherichia coli (E. It evaluated their ability to inhibit pathogenic & antibiotic-resistant bacteria, including Staphylococcus aureus (S.
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Selon Khan R (2009)
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Cáncer: tratamiento adyuvante del carcinoma colorrectal, de mama, de próstata, de esófago y de útero
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Abd El Azim M et al (2014)
Extrait Eleven phenolic compounds were identified from the methanolic extract of Cloves flowers buds (Syzygium aromaticum L.) by chromatographic methods. The results showed that the IC50 were (31 μg/mL for anti-colon cancer, 29.7 μg/ml for anti-breast cancer and 18.7 μg /ml for anti-hepatic cancer).
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Selon Dwivedi V et al (1989)
Extrait Water, ethanol & extracts were screened for anti-proliferative activity against HeLa (cervical cancer), MCF-7 (ER + ve) & MDA-MB-231 (ER – ve) breast cancer, DU-145 prostate cancer & TE-13 esophageal cancer cell lines, along with normal human peripheral blood lymphocytes. The objective of the present study is to compare the in vitro anticancer activities of three different extracts of Clove (Syzygium aromaticum L), a commonly used spice & food flavouring agent, against different kinds of cancer cell lines of various anatomical derivations.
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Selon Yassin MT (2020)
Extrait aromaticum extracts against HCT human colon carcinoma was appraised using MTT assay.
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Selon Banerjee S (2006)
Extrait Clove, the Sun-dried un-opened flower Bud from the plant Syzygium aromaticum L. Incidence of hyperplasia, dysplasia and carcinoma in situ evident in the carcinogen control group on the 8th, 17th and 26th weeks, respectively, were effectively reduced after treatment with clove infusion.
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Selon DA COSTA JS (2020)
Extrait The oils presented many biological activities, especially antimicrobial (antifungal & antibacterial), anticholinesterase, anticancer (breast, gastric, melanoma, prostate), antiprotozoal (Leishmania spp.), antioxidant, acaricidal, antinociceptive & anti-inflammatory. These studies can contribute to the rational & economic exploration of Eugenia & Syzygium species once they have been identified as potent natural & alternative sources to the production of new herbal medicines,.
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Selon Abd El Azim M et al (2014)
Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.
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+3 indications · ~4 indicaciónes corregidas · −2 indications · −7 sinergias · +8 referencias · ~44 referencias corregidas · −1 referencia
Solo contadores y dominios: los nombres de indicaciones y sinergias no se listan aquí (abrir la ficha en la aplicación). Los textos de las referencias añadidas, corregidas o retiradas están abajo.
+8 referencias — mostrar textos
Potensi Senyawa Eugenol dari Cengkeh (Syzygium aromaticum) sebagai Inhibitor Protease HIV-1 (PR). Unesa Jl of Chem, 12(1); 26–30, 2023-
AñadidaComputational Evaluation of the Potential of Salicylate Compound from Syzygium aromaticum on Carbonic Anhydrase I as a Gastric Acid Stimulant, Pharmacogn Jl, 2023-Abstract: This article explores the potential of the salicylate compound (Syzygium Aromaticum) as a stimulant for Carbonic Anhydrase I in gastric acid secretion, using a computational approach. The research methods include molecular modeling with Pymol & Pyrex, determination of compound structure & interactions with Protein Plus, & examination of physicochemical properties using the Lipinski Rule. The results show that the Binding…
AñadidaClove leaf ethanol extract (Syzygium aromaticum L. Merr. & Perr) is formulated as antiseptic liquid soap, Jl of Physics: Conf Series, 2021-Abstract: Secondary metabolite compound is compound that have medicinal properties, cosmetics, dyes, fragrances. Secondary metabolite compound can be modified into one form of pharmaceutical dosage, namely cosmetic products. One of the cosmetic products is liquid soap preparation. Soap that can kill bacteria is known as antiseptic soap. Clove leaves (Syzygium aromaticum L. Merr. & Perr) contain eugenol compounds which have antiseptic properties. This stu…
AñadidaAntioxidant, anti-inflammatory activities & acute toxicity of the polyherbal formulation: Romix®, Pharm Biol, 50(6):720-6. 2012-Abstract: Polyherbal formulations containing different plants are used for the treatment of various diseases. Romix® powder is a polyherbal formulation consisting of 14 traditionally used herbs & is used as a food supplement. There is no information about pharmaceutical activities of Romix®. Objective: This study determined the total phenolic & total flavonoid content, & investigated the antioxidant & anti-inflammatory activities & acute toxicity of Romix®. Materia…
AñadidaRoles of Syzygium in Anti-Cholinesterase, Anti-Diabetic, Anti-Inflammatory, & Antioxidant: From Alzheimer's Perspective, Plants (Basel), 11(11):1476. 2022-Abstract: Alzheimer's disease (AD) causes progressive memory loss & cognitive dysfunction. It is triggered by multifaceted burdens such as cholinergic toxicity, insulin resistance, neuroinflammation, & oxidative stress. Syzygium plants are ethnomedicinally used in treating inflammation, diabetes, as well as memory impairment. They are rich in antioxidant phenolic compounds, which can be multi-target neuroprotective agents against AD. This…
AñadidaIn Silico Study on the Inhibition of Sitogluside from Clove Plant (Syzygium aromaticum) on Interleukin 2 in B & T Cell Proliferation, Pharmacogn Jl, 15(4):575-80, 2023-Abstract: This research discusses an in-silico study of sitogluside found in the clove plant (Syzygium aromaticum) as a potential inhibitor of B & T cell proliferation through interaction with Interleukin-2. This study utilizes methods such as Swiss Target Prediction, Pymol, Pyrex, Protein Plus, & Lipinski's Rule to predict the biological activity and pharmacokinetic characteristics of sitogluside. From the docking simulation…
AñadidaInteraction of Masilinic Acid from Clove Plant (Syzygium aromaticum) with CD81 Antigen in Inhibiting HIV Virus Regulation in Silico, Pharmacogn Jl, 15(4):484-8, 2023-Abstract: This research explores the interaction of Masilinic Acid from the clove plant (Syzygium aromaticum) with the CD81 antigen to inhibit HIV virus regulation in silico. Using computational methods such as Pymol, Pyrex, & Protein Plus, we demonstrate that Masilinic Acid can significantly interact with the CD81 antigen. The obtained data shows binding affinities of -6.4, -6.2, and -5.7, & RMSD values of 0, 1.885, & 1.952. Fur…
AñadidaAnti-hyperglycemic & anti-hyperlipidemic effect of Syzygium aromaticum (L.) Merr. & L.M. Perry via in vitro, in vivo & in silico models, Plant Sci Today, 2026-Abstract: Diabetes mellitus (DM) is one of the most prevalent endocrine disorders, projected to affect over 300 million people by 2025. Despite the availability of several anti-diabetic drugs, their adverse effects have prompted the search for safer alternatives. The present study investigates the anti-hyperglycemic & anti-hyperlipidemic effects of the ethanolic extract of Syzygium aromaticum (L.) Merr. & L.M. Perry (clove). Dried clo…
AñadidaAção de oleos essentials no controle de sigatoka-negra (Mycosphaerella fijiensis Morelet) de bananeiras (Musa sp). Dissertação Univ Estadual Paulista, Inst de Biociências, Brasil. 68, 2009-Abstract: Brazil is one of the biggest banana producers, the second most consumed fruit in this country & the fourth most important food worldwide. Its production has been drastically harmed mainly because of the Mycosphaerella fijiensis Morelet pathogen, the causal agent of black Sigatoka disease. The current control of this fungus applies great amounts of agrochemicals which burdens the production, cont…
CorregidaSyzygium aromaticum-derived triterpenes modulate intestinal glucose handling in streptozotocin-induced diabetic rats; Thesis: Univ of Kwazulu-Natal, 2014,
CorregidaCompounds from Syzygium aromaticum possessing growth inhibitory activity against oral pathogens. Jl of Natural Products (Lloydia) 59, 987–90, 1996.
CorregidaAnti-Tumor, Antioxidant & Antimicrobial & the Phenolic Constituents of Clove Flower Buds (Syzygium aromaticum), Jl of Microbial & Biochem Technol, 2014-Abstract: Eleven phenolic compounds were identified from the methanolic extract of Cloves flowers buds (Syzygium aromaticum L.) by chromatographic methods. Efficiency of the methanolic extract of licorice roots as anticancer agent for breast, colon and liver was tested. The results showed that the IC50 were (31 μg/mL for anti-colon cancer, 29.7 μg/ml for anti-breast cancer and 18.7 μg /ml for anti-hepatic cancer). This extract showed strong …
CorregidaAção de óleo esencial de Syzygium aromaticum (L) Merr. y L. M. Perry sobre as hifas de alguns funguos fitopatogénicos. The Brazilian Jl of Med Plants 13:240-5, 2011-Abstract: This study aimed to investigate the action of clove [Syzygium aromaticum essential oil on the in vitro mycelial growth of the phytopathogenic fungi Rhizoctonia solani, Fusarium solani, Fusarium oxysporum & Macrophomina phaseolina. Analysis by gas chromatography-mass spectrometry allowed the identification of eugenol (83.6 percent), eugenyl acetate (11.6 percent) & caryophyllene (4.2 percent). Microscopic evaluation of …
CorregidaClove (Syzygium aromaticum): a precious spice, Asian Pac Jl Trop Biomed., 2014, 4(2): 90–96.
CorregidaMedicinal plant treatments for fleas and ear problems of cats and dogs in British Columbia, Canada. Parasitol Res. 2008;103(4):889-98.
CorregidaPotential interactions between alternative therapies & Warfarin. Am Jl Health Syst Pharm. 2000;57(13):1221-7.
CorregidaPermanent local anaesthesia & anhidrosis after clove oil spillage. Lancet 1(8329):882, 1983.
CorregidaAntiplatelet principles from a food spice clove (Syzygium aromaticum L). Prostaglandins Leukot Essent Fatty Acids. 1993;48(5):363-72.
CorregidaHigh-performance thin-layer chromatography densitometric method for the simultaneous determination of three phenolic acids in Syzygium aromaticum (L.) Merr. & Perry. Jl AOAC Int. 2008;91(5):1169-73.
CorregidaEVALUATION OF ANTIOXIDANT ACTIVITY OF CLOVE (SYZYGIUM AROMATICUM), Int. Jl. Chem. Sci.,13(1), 2015: 23-30,
Corregidathe study of antiepileptic activity of clove oil in chemical induced convulsions in mice, Inter Jl of Basic & Clinical Pharmacol, 4 :5 (2015) -Abstract: The objective was to evaluate & compare the effect of an extract of essential oil of clove with the standard sodium valproate on Pentylenetetrazole (PTZ) induced seizures in animal models. Methods: A total of 30 mice were taken, they were given a chemo shock at the concentration of 60 mg/kg using PTZ. 30 mice were divided into 5 groups of 6 animals each the control group received distilled water 5 ml/kg i.p., standard received injection sod…
CorregidaToxic effects of water//alcoholic extract of Syzygium aromaticum on sperm quality, sex hormones & reproductive tissues in male mouse, IUFS Jl Biol 2012, 71(22): 95-102,
Corregidathe study of the insecticide effect of the essential oil of Syzygium aromaticum L. against larvae of Tuta absoluta, Inter Jl of Innov & Scientific Res, 20 :1) :188-94, 2016-Abstract: The tomato leaf miner, Tuta absoluta (Meyrick), is a major pest of tomatoes in Morocco. Since its spread in the 1970s, chemical control was the main method of control. However, reduced effectiveness of some of the recommended insecticides has been observed since the 1980s. This study aims to propose alternative solutions based on the use of natural products "bioinsecticide" to fight against the tomato leaf mine…
Corregidaantimicrobial activity of clove & Cinnamon essential oils against Listeria monocytogenes in pasteurized Milk. Jl Food Prot. 2007;70(12):2757-63.-Abstract: The antimicrobial activity of essential oils (EOs) of cinnamon bark, leaf & clove against Listeria monocytogenes Scott A were studied in semi-skimmed milk incubated at 7 degrees C for 14 days and at 35 degrees C for 24 h. The MIC was 500 ppm for cinnamon bark EO and 3,000 ppm for the cinnamon leaf and clove EOs. These effective concentrations increased to 1,000 ppm for cinnamon bark EO, 3,500 ppm for clove EO, and 4,000 ppm for cinnamon l…
CorregidaClove (Syzygium aromaticum) Extract has Antibacterial & Antifungal Effects against Human Scalp Microbes, Asian Jl of Biol & Life Sci, 13(2):491-9, 2024-Abstract: Clove (Syzygium aromaticum) is rich in phytochemicals, making it a good pain reliever & disinfection agent against many microbes, including those that might infect hair. Materials & Methods: This study screened microbes isolated from the human scalp & subjected them to different clove aqueous extraction concentrations. 6 volunteers provided samples from their scalps, & two microorganisms were found: Staphylococcus aureus & Cryptoco…
CorregidaEFFECT OF ETHANOL EXTRACT OF ARECA CATECHU & SYZYGIUM AROMATICUM ON GLUTATHIONE-S-TRANSFERASE OF COTYLOPHORON COTYLOPHORUM, World Jl of Pharm & Pharmaceut Sci, 4(10):1117-25, 2015.-Abstract: The anthelmintic activity of ethanol extracts of Areca catechu & Syzygium aromaticum on Glutathione-S-transferase activity of the digentic trematode Cotylophoron cotylophorum was studied. The parasites were exposed to five sublethal concentrations of ethanol extracts of Areca catechu & Syzygium aromaticum for 2, 4 & 8h. Glutathione-S-transferase was assayed in control & drug treated flukes. Maximum inh…
CorregidaThe efficacy of clove oil as an anesthetic & in euthanasia procedure for small-sized tropical fishes, Braz Jl Biol. 2017, 77(3):444-50. –Abstract: Clove oil is used as a fish anesthetic because it is a natural and inexpensive product with low toxicity risks. The goal of the present study was to determine the appropriate concentration of clove oil for small-sized tropical fish to be used in mark-recapture studies or when individuals are to be sacrificed. We applied three different clove oil concentrations (D1=0.05 mL, D2=0.10 mL and D3=0.20 mL per 500 mL of water) on three small-sized fish s…
CorregidaSyzygium aromaticum ethanol extract reduces AlCl3-induced neurotoxicity in mice brain through regulation of amyloid precursor protein & oxidative stress gene expression. Asian Pac Jl Trop Med 2018; 11:123-30-Abstract: To investigate the neuroprotective effects of Syzygium aromaticum extract (500 mg/kg) on AlCl3 (300 mg/kg)-induced mouse model of oxidative stress & neurotoxicity. Methods: An ethanolic extract of S.A seeds was prepared and the active compounds were identified using nuclear magnetic resonance spectroscopy. BALB/ c mice were divided into five groups (negative control, AlCl3-tre…
CorregidaIllnesses possibly associated with smoking clove cigarettes. Morb Mortal Wkly Rep;34(21):297-9, 1985.
CorregidaIN VITRO EFFECT OF SYZYGIUM AROMATICUM ON THE MOTILITY & ACETYLCHOLINESTERASE OF COTYLOPHORON COTYLOPHORUM, Int Jl of Vet & Anim Sci Res, 43(3) :187-94, 2014.-Abstract: The anthelmintic activity of Syzygium aromaticum on the motility & acetylcholinesterase (AChE) activity of the digentic trematode Cotylophoron cotylophorum was studied in vitro. The flukes were exposed to various concentrations of hexane, chloroform, ethyl acetate & ethanol extract of S aromaticum & the motility & mortality of the parasite was observed. As ethanol extract was very effective, further studies were carried out …
CorregidaGenotoxicity induced by Eugenia caryophyllata infusion, Jl Toxicol Environ Health A, 71(7):439-44, 2008-Abstract: Several therapeutic properties have been described for Eugenia caryophyllata (clove). In the present study the infusion of EC was evaluated in a series of bacterial & cell-free assays in order to determine genotoxic potential. Negative results were obtained in the SOS Chromotest & in the Salmonella reversion assay using strains TA97a, TA98, TA100, & TA102. However, in a forward mutagenesis assay an increase in mutagenesis & high cytotoxicity was observed with the CC104 mutMmutY …
CorregidaChemical composition, antibiotic promotion & in vivo toxicity of Piper nigrum & Syzygium aromaticum essential oil, Afri Jl of Biochem Res, 11(10) :58-71, 2017,
CorregidaPhytochemical Screening & Antimicrobial Sensitivity of Clove Flower (Syzygium aromaticum, L. Merrill & Perry) Bud on Dental Pathogens. Int Jl of Pharm & Pharma Res, :3: 2, 2015.
CorregidaModulatory influences of clove (Caryophyllus aromaticus, L) on hepatic detoxification systems & bone marrow genotoxicity in male Swiss albino mice. Cancer Lett. 1991;60(1):67-73.
CorregidaAntibacterial activity of Syzygium aromaticum (clove) against uropathogens producing ESBL, MBL, & AmpC beta-lactamase: Are we close to getting a new antibacterial agent? Jl of Family Med Prim Care, 2020-Abstract: the present study was done to access the antibacterial activity of clove (Syzygium aromaticum) against extended-spectrum beta-lactamase (ESBL), metallo-beta-lactamase (MBL), & AmpC beta-lactamase-producing gram-negative bacteria causing urinary tract infection. Methods: A total of 221 gram-negative uropathogens were isolated & screened for beta-lactamase (ESBL, MBL, & AmpC) product…
CorregidaImmunomodulatory effects of clove (Syzygium aromaticum) constituents on macrophages: in vitro evaluations of aqueous and ethanolic components, Jl Immunotoxicol. 2015;12(2):124-31.-Abstract: The present work sought to investigate potential suppressive effects on mouse macrophages by in vitro treatment with clove (Syzygium aromaticum) ethanolic extracted essential oil (containing eugenol) or its water-soluble extract. Using doses (ranging from 0.001-1000 µg/ml) of each material freshly prepared in the laboratory, cell survival and production of nitric oxide (NO), tumor necrosis factor (TNF)-α…
CorregidaPotential of clove of Syzygium aromaticum in development of a therapeutic agent for periodontal disease. A review, S A D Jl, 70(3à :108 – 15, 2015,
CorregidaEffect of Syzygium aromaticum on the growth of cancer cells & microbes, Dissertation: Department of Biotechnol & Environ Sci, Thapar Univ, Patiala-2014,
CorregidaAntifungal activities of the essential oils in Syzygium aromaticum (L.) Merr & Perry & Leptospermum petersonii Bailey and their constituents against various dermatophytes. Jl of Microbiol. 2007; 45:460–5.-Abstract: This study was carried out in order to investigate the potential of using plant oils derived from Leptospermum petersonii Bailey & Syzygium aromaticum L. Merr. Et Perry as natural antifungal agents. The antifungal effects of essential oils at concentrations of 0.05, 0.1, 0.15 & 0.2 mg/ml on the dermatophytes Microsporum canis (KCTC 6591), Trichophyton mentagrophytes (KCTC 6077), …
CorregidaAntifungal activity of the clove essential oil from Syzygium aromaticum on Candida, Aspergillus & dermatophyte species. Jl Med Microbiol. ; 58(Pt 11):1454-62, 2009.-Abstract : The composition and antifungal activity of clove essential oil (EO), obtained from Syzygium aromaticum, were studied. Clove oil was obtained commercially and analysed by GC and GC-MS. The EO analysed showed a high content of eugenol (85.3 %). MICs, determined according to Clinical and Laboratory Standards Institute protocols, and minimum fungicidal concentration were used to evaluate the antifungal activity of the clo…
CorregidaIN VITRO ACTIVITY EXTRACTS OF SYZYGIUM AROMATICUM AGAINST ASPERGILLUS SPECIES, 7th Advances Against Aspergillosis conference: 201
CorregidaANTIBACTERIAL & ANTICANDIDAL SCREENING OF CERTAIN TRADITIONALLY USED INDIAN MEDICINAL PLANTS AGAINST MULTI- DRUG RESISTANT HUMAN PATHOGENS, Int Jl of Sci & Nat, 5(3):423-32, 2016.-Abstract: Ethanolic & aqueous extracts of 20 Indian medicinal plants traditionally used in medicine were studied for their antibacterial & anticandidal activity against five multi – drug resistant bacteria i. e. Staphylococcus aureus (NCIM 2079), Bacillus subtilis (NCIM 2063), Escherichia coli (NCIM 2065), Salmonella typhimurium (NCIM 2501), Streptococcus pneumoniae (NCIM 5281) & a yeast Candida albicans (NCIM 347…
CorregidaFlavonoid triglycosides from the seeds of Syzygium aromaticum. Carbohydr Res. 2006;341(1):160-3.-Abstract: Two new apigenin triglycosides, apigenin 6-C-[beta-D-xylopyranosyl-(1'''-->2'')-bêta-D-galacto-pyranoside]-7-O-bêta-D-glucopyranoside & apigenin 6-C-[beta-D-xylopyranosyl-(1'''-->2'')-beta-D-galactopyranoside]-7-O-beta-D-(6-O-p-coumaryl gluco-pyranoside) were isolated from the ethanol extract of the seeds of Syzygium aromaticum m. Their structures were elucidated by chemical & spectral analysis (UV, FABMS, 1H, 13C NMR, HMQC, HMBC, NOESY & DEPT).
Corregidathe insecticidal activity of some extracts & oils of some tropical plants against the Yam moth Euzopherodes Vapidella Mann (Lepidoptera: Pyralidae), Ife Jl of Sci, 6(1): 10 -3, 2004-Abstract: The ethanolic extracts & oils of eight tropical plants were evaluated under laboratory conditions for their relative toxicities to the eggs &é larvae of the Yam moth, Euzopherodes Vapidella. Contact toxicity of the extract & oil on the eggs & larvae of the Yam moth was tested by treating 15g of Dioscorea alata measuring (4cmx4cmx1.5cm) with 0.5ml & 0.1ml of ethanol and oil extract in separate Petri dis…
CorregidaThe Vapor activity of oregano, Perilla, tea tree, lavender, clove, & geranium oils against A Trichophyton mentagrophytes in a closed box. Jl Infect Chemother. 2006;12(6):349-54.-Abstract: The vapor activity of six essential oils against a Trichophyton mentagrophytes was examined using a closed box. The antifungal activity was determined from colony size, which was correlated with the inoculum size. As judged from the minimum inhibitory dose & the minimum fungicidal dose determined after vapor exposure for 24 h, the vapor activity of the six EOs was ranked in the following order: oregano > c…
CorregidaComparative anticancer potential of clove (Syzygium aromaticum) —An Indian spice—against cancer cell lines of various anatomical origin. Asian Pac Jl of Cancer Prevention. 12: 1989-93, 2011-Abstract: The objective of the present study is to compare the in vitro anticancer activities of three different extracts of Clove (Syzygium aromaticum L), a commonly used spice & food flavouring agent, against different kinds of cancer cell lines of various anatomical derivations. Water, ethanol & extracts were screened for anti-proliferative activity against HeLa (cervical cancer), MCF-7 (ER + ve) & MD…
CorregidaEffects of spices, Papaver somniferum, Elettaria cardamomum, Foeniculum vulgare & Syzygium aromaticum on growth promotion in Macrobrachium malcolmsonii early juveniles. Int Jl Pure Appl Biosci 2: 120-31. 2014a.-Abstract: A 45 days feeding trial was conducted on Macrobrachium malcolmsonii (2.28±0.08 cm & 0.11±0.04 g) fed with seeds of Papaver somniferum (poppy), Elettaria cardamomum (cardamom) & Foeniculum vulgare (fennel) & flower buds of Syzygium aromaticum (clove) incorporated (1%, 3% & 5% with basal diet) feeds. Feed without inclusion of any spice was served as control. These spices were…
CorregidaOBTAINING OF THE ESSENTIAL OIL OF SYZYGIUM AROMATICUM, IDENTIFICATION OF EUGENOL & ITS EFFECT ON STREPTOCOCCUS MUTANS, l 3 :4 DOI: 10.17126/JORALRES.2014.051,
CorregidaClove & eugenol in noncytotoxic concentrations exert immunomodulatory/ anti-inflammatory action on cytokine production by murine macrophages. Jl Pharm Pharmacol. 2012;64(4):610-6.-Abstract: The extract & essential oil of clove are widely used because of their medicinal properties. Eugenol is the most important component of clove, showing several biological properties. Herein we have analysed the immunomodulatory/anti-inflammatory effect of clove and eugenol on cytokine production (interleukin (IL)-1β, IL-6 & IL-10) in vitro. METHODS: Macrophages were incubated with clove or eugenol (5, 10, …
CorregidaEvaluating the multifaceted bioactivity of Syzygium aromaticum essential oil: the central role of eugenol, Turk Jl Biol, 49(1):102-117. 2025-Abstract: Syzygium aromaticum L. is a versatile plant traditionally used to treat digestive & respiratory issues, improve oral health, and relieve pain, particularly in regions such as Southeast Asia, South Asia, & parts of the Middle East. It’s essential oil (EO), predominantly composed of eugenol, is rich in bioactive compounds. This study aims to clarify the specific contribution of eugenol to the antioxidant, antibacterial, antifungal, & insecticid…
CorregidaNeuropharmacological studies on Syzygium aromaticum (clove) essential oil, Inter Jl of Pharma Sci, 5 :2 (2015): 1013-8-Abstract: This study was planned to investigate the anticonvulsant, anxiolytic and hypnotic activities of clove essential oil (CEO). The anticonvulsant activity of CEO (0.025, 0.05- & 0.1-ml kg-1 BW i.p) was evaluated in mice using the strychnine & picrotoxin-induced convulsion models. Its anxiolytic activity was evaluated using open field test (OFT) while the thiopental sodium induced sleep test was used to evaluate the hypnotic activity. The phytochemical analysis of oil…
CorregidaAbstract: When taken by mouth: Clove is commonly consumed in foods. There isn't enough reliable information to know if taking clove in larger amounts is safe or what the side effects might be. When applied to the skin: Clove oil or cream containing clove flower is possibly safe. But applying clove oil in the mouth or on the gums can sometimes cause irritation & gum damage. Applying clove oil or cream to the skin can sometimes cause burning & skin irritation. When inhaled: Smoke from clove cigarettes is likely unsafe & can cause side effects such as breathing problems & lung disease.
CorregidaRodriguez O et al, OBTAINING OF THE ESSENTIAL OIL OF SYZYGIUM AROMATICUM, IDENTIFICATION OF EUGENOL & ITS EFFECT ON STREPTOCOCCUS MUTANS, l 3 :4 DOI: 10.17126/JORALRES.2014.051,
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