Tamarindus indica (Tomaren-si) : propiedades medicinales en extracción alcohólica

Tamarindus indica (Tomaren-si, Tamarino seguro, Tamarin sûr, Tamarin, for sure) — familia Caesalpiniacées.

Sinónimos científicos : Tamarindus occidentalis-Gaertn, T. officinalis-Hook, T. Umbrosa-Salisb..

Fuentes externas reconocidas asociadas a esta monografía: TRAMIL y Farmacopea francesa.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 21 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 65 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Cáncer: tratamiento adyuvante del carcinoma hepático

   Parte usada: Pulpa de la fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bressiani P (2021)

     Extrait The antioxidant activity by the DPPH radical scavenging assay & the cytotoxic activity against the liver tumor cells of Rattus norvegicus were determined. The pulp of TI from MS is a promising source of bioactive compounds with antioxidant & cytotoxic/ antiproliferative activities.

   • Selon El Badwi Samia MA (s.d.)

     Extrait The aim of this study is to investigate the effect the fruit pulp ethanolic extract of Tamarindus indica in protecting liver damage induced by CCL4 Thirty Wistar rats were used and divided into 5 groups of 6 rats each, the first group served as control and was given orally vehicle saline at 1ml/kg/day, the second group acts as CCL4 control and received CCL4 to induced damage to the liver, the Third group treated with ethanolic extract of Tamarindus indica at 150 mg/kg/day & CCL4, the fourth group was treated with Silymarin as standard drug & CCL4 & the fifth group was treated with 150 mg/kg/day ethanolic extract of T indica alone, the experiment continued for 5 days, liver enzymes, AST, ALT & ALP were recorded as well as total Bilirubin, total protein and albumin, haematological parameters include RBCs, Hb, PCV, MCV & MCHC were measured. indica ameliorated the damage caused by CCL4 by lowering the levels of AST, ALT, ALP & the concentration of Bilirubin & this effect was verified by improvement of histopathological picture in the livers of the group treated by the plant compared with the liver of CCL4 group which exhibited severe centrilobular necrosis and fatty vacuolation.

   • Selon Ranjan R (2009)

     Extrait Changes in plasma biochemistry suggested less hepatic and renal damages in animals receiving plant extracts along with fluorinated water in comparison to that receiving fluorinated water alone.

   • Selon LIM C (2013)

     Extrait indica fruit pulp to hypercholesterolaemic hamsters also protected against oxidative damage by increasing hepatic antioxidant enzymes, antioxidant activities & preventing hepatic lipid peroxidation.

   • Selon Pimple BP (2007)

     Extrait Protective effect of Tamarindus indica Linn (Caesalpiniaceae) was evaluated by intoxicating the rats with paracetamol (1 g/kg p.o.) for seven days. Liver weight variation, thiopentone-induced sleeping time and histopathology were studied on 13 th day.

2. 2

   Hepatotoxicidad inducida por el paracetamol

   Parte usada: semilla.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shammi NJ (2024)

     Extrait Objective: This study was aimed to explore the effectiveness of ethanolic extract of seed of TI on liver weight when liver is intoxicated with paracetamol and to compare it with the effects of Vitamin E, a known hepatoprotectant. Results: In this study, the mean (±SD) liver weight was 4.08±0.23 in control group, 6.27±0.68 in only paracetamol treated group, 5.22±0.72 & 4.57±0.86 in paracetamol along with seed extract of TI & vitamin E treated group respectively.

   • Selon Ranjan R (2009)

     Extrait Changes in plasma biochemistry suggested less hepatic and renal damages in animals receiving plant extracts along with fluorinated water in comparison to that receiving fluorinated water alone. Preliminary results revealed these plant extracts have some potential to mitigate fluoride toxicity,.

   • Selon Pimple BP (2007)

     Extrait Protective effect of Tamarindus indica Linn (Caesalpiniaceae) was evaluated by intoxicating the rats with paracetamol (1 g/kg p.o.) for seven days. The aqueous extracts of different parts of TI such as fruits, leaves (350 mg/kg p.o.) & Unroasted seeds (700 mg/kg p.o.) were administered for 9 days after the third dose of paracetamol.

   • Selon El Badwi Samia MA (s.d.)

     Extrait The aim of this study is to investigate the effect the fruit pulp ethanolic extract of Tamarindus indica in protecting liver damage induced by CCL4 Thirty Wistar rats were used and divided into 5 groups of 6 rats each, the first group served as control and was given orally vehicle saline at 1ml/kg/day, the second group acts as CCL4 control and received CCL4 to induced damage to the liver, the Third group treated with ethanolic extract of Tamarindus indica at 150 mg/kg/day & CCL4, the fourth group was treated with Silymarin as standard drug & CCL4 & the fifth group was treated with 150 mg/kg/day ethanolic extract of T indica alone, the experiment continued for 5 days, liver enzymes, AST, ALT & ALP were recorded as well as total Bilirubin, total protein and albumin, haematological parameters include RBCs, Hb, PCV, MCV & MCHC were measured. indica ameliorated the damage caused by CCL4 by lowering the levels of AST, ALT, ALP & the concentration of Bilirubin & this effect was verified by improvement of histopathological picture in the livers of the group treated by the plant compared with the liver of CCL4 group which exhibited severe centrilobular necrosis and fatty vacuolation.

   • Selon LIM C (2013)

     Extrait indica fruit pulp to hypercholesterolaemic hamsters also protected against oxidative damage by increasing hepatic antioxidant enzymes, antioxidant activities & preventing hepatic lipid peroxidation.

3. 3

   Hepatitis, esteatosis hepática, ictericia

   Parte usada: Pulpa de la fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon El Badwi Samia MA (s.d.)

     Extrait The aim of this study is to investigate the effect the fruit pulp ethanolic extract of Tamarindus indica in protecting liver damage induced by CCL4 Thirty Wistar rats were used and divided into 5 groups of 6 rats each, the first group served as control and was given orally vehicle saline at 1ml/kg/day, the second group acts as CCL4 control and received CCL4 to induced damage to the liver, the Third group treated with ethanolic extract of Tamarindus indica at 150 mg/kg/day & CCL4, the fourth group was treated with Silymarin as standard drug & CCL4 & the fifth group was treated with 150 mg/kg/day ethanolic extract of T indica alone, the experiment continued for 5 days, liver enzymes, AST, ALT & ALP were recorded as well as total Bilirubin, total protein and albumin, haematological parameters include RBCs, Hb, PCV, MCV & MCHC were measured. indica ameliorated the damage caused by CCL4 by lowering the levels of AST, ALT, ALP & the concentration of Bilirubin & this effect was verified by improvement of histopathological picture in the livers of the group treated by the plant compared with the liver of CCL4 group which exhibited severe centrilobular necrosis and fatty vacuolation.

   • Selon Ranjan R (2009)

     Extrait Changes in plasma biochemistry suggested less hepatic and renal damages in animals receiving plant extracts along with fluorinated water in comparison to that receiving fluorinated water alone.

   • Selon LIM C (2013)

     Extrait indica fruit pulp to hypercholesterolaemic hamsters also protected against oxidative damage by increasing hepatic antioxidant enzymes, antioxidant activities & preventing hepatic lipid peroxidation.

   • Selon Pimple BP (2007)

     Extrait Protective effect of Tamarindus indica Linn (Caesalpiniaceae) was evaluated by intoxicating the rats with paracetamol (1 g/kg p.o.) for seven days. Liver weight variation, thiopentone-induced sleeping time and histopathology were studied on 13 th day.

   • Selon Bressiani P (2021)

     Extrait The antioxidant activity by the DPPH radical scavenging assay & the cytotoxic activity against the liver tumor cells of Rattus norvegicus were determined.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.