Ziziphus mauritiana (Jijib) : propiedades medicinales en extracción alcohólica

Ziziphus mauritiana (Jijib, Árbol de azufaifo, Jujubier, Jujube tree) — familia Rhamnacées.

Sinónimos científicos : Rhamnus jujuba L., Rhamnus mauritiana Willemet, Ziziphus jujuba (L.) Gaertn., Ziziphus jujuba (L.) Lam., Z. Poiretti-Don, Z. tomentosa-Poir, Z. rotundata DC., Z. sphaerocarpa auct Non Tul.

Fuentes externas reconocidas asociadas a esta monografía: Farmacopea francesa.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 24 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 91 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Diabetes mellitus tipo II

   Parte usada: semilla.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon BHATHIA A (2008)

     Extrait In the present study, the hypoglycemic effect of seed extract of Ziziphus mauritiana in alloxan-induced diabetic mice was assessed. Seed extract was administered orally at doses of 100, 400, & 800 mg/kg body weight (BW) & also in combination with Glyburide (800 mg/kg seed extract & 10 mg/kg glyburide) to different groups of mice (normal & alloxan-treated diabetic mice).

   • Selon RAHBARDAR MG (2024)

     Extrait This review evaluates the therapeutic potential of Ziziphus jujuba & its main components in managing complications of metabolic syndrome, including diabetes, dyslipidemia, obesity, & hypertension. They also improve insulin sensitivity by modulating AMP-activated protein kinase (AMPK) activity & regulating insulin signaling proteins & glucose transporters.

   • Selon Li YM (2023)

     Extrait SZJ-2 can improve the hyperglycemic by increasing the glucose consumption, improving the superoxide dismutase (SOD), hexokinase (HK), pyruvate kinase (PK) activities, & decrease the MDA content of insulin resistant HepG2 cells. Conclusion: These results indicating that the SZJ-1 & SZJ-2 might improve the insulin resistant symptoms by improving the energy metabolic level &increasing the glycogen synthase activity of HepG2 cells.

   • Selon Jarald EE (2009)

     Extrait Jarald EE et al, Antidiabetic activity of extracts and fraction of Ziziphus mauritiana.

2. 2

   Hepatitis, cirrosis, esteatosis hepática,

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Huang S (2021)

     Extrait Jujube polysaccharides (JP) is one of the active food sourced glycans in dietary fruit of Ziziphus jujuba, which has been considered for the treatment of blood deficiency.

   • Selon Dahiru D (2005)

     Extrait mauritiana leaf extract protected rats against carbon tetrachloride liver injury by significantly lowering aspartate aminotransaminase (AST), alanin & (ALT), alkaline phosphatase (ALP), total Bilirubin (TB), & lipid peroxide levels compared to control. Protective effect of ethanol extract of Z mauritiana leaf was studied on carbon tetrachloride induced liver damage.

   • Selon Dahiru D (2008)

     Extrait Dahiru D et al, Evaluation of the antioxidant effects of Ziziphus mauritiana Lam leaf extracts against chronic ethanol-induced hepatotoxicity in rat liver.

   • Selon Dahiru D (2009)

     Extrait Dahiru D et al, Effect of aqueous extract of Ziziphus mauritiana leaf on cholesterol & triglycerides level in serum & liver of rats administered alcohol.

   • Selon SAID A (2010)

     Extrait The volatile constituents from fresh aerial parts (leaves & flowers) of Zizyphus jujuba & fruits of Zizyphus spina-Christi (Rhamnaceae) were analyzed by GC & GC-MS. spina-Christi was comprised mainly of fatty acids & their esters, of which dodecanoic acid (22.4 %) was the main component.

3. 3

   Cáncer: tratamiento adyuvante del carcinoma de mama

   Parte usada: fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hosmer R (2015)

     Extrait jujube fruit on the proliferation of breast cancer cells by MTT assay and the antioxidant by FRAP, haematological & biochemical alterations caused by NMU(Methyl-Nitroso-Urea)-induced mammary carcinogenesis in rats. Conclusions: These findings indicate that the ZJ ameliorates the adverse effects of NMU carcinogenesis & could be useful for treating mammary tumours in humans.

   • Selon Plastina P (2012)

     Extrait Identification of bioactive constituents of Ziziphus jujube fruit extracts exerting antiproliferative & apoptotic effects in human breast cancer cells.

   • Selon Pauloi L (2024)

     Extrait ziziphus mauritiana Lam., a tropical fruit-bearing tree commonly known as Bidara tree in Malaysia, has a long & rich history of use in traditional medicine. Notably, many of these identified compounds have demonstrated promising antibacterial, antioxidant, anti-inflammatory, & anticancer properties in previous scientific studies.

   • Selon KHANAM A (2025)

     Extrait The present study aimed to assess the antioxidant & anti-inflammatory activities of polyphenol-rich extracts of seedless variety of Ziziphus mauritiana (SZM). The anti-inflammatory activity was evaluated on carrageenan-induced rat model & suppression of inflammatory biomarkers (Interleukin-6, Tumor necrosis factor-α & CRP) were studied.

   • Selon Choi S-H (2012)

     Extrait Changes in free amino acid, protein, & flavonoid content in jujube (Ziziphus jujube) fruit during eight stages of growth & antioxidative & cancer cell inhibitory effects by extracts.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.