Garcinia mangostana (Mangoustan) : vertus médicinales en extraction alcoolique

Garcinia mangostana (Mangoustan, Mangosteen) — famille Clusiacées.

Synonymes scientifiques : Garcinia malaccensis-Hook f., Mangostana Garcinia-Gaertn.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 22 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 163 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome buccal, leucémique, hépatique, colorectal, squameux epidermoide & du mélanome, mammaire

   Partie usitée : Fruit (péricarpe).

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ho CK (2002)

     Extrait We extracted & purified 6 xanthone compounds from the rinds (peel) of the fruits of Garcinia mangostana, using partitioned chromatography & then tested the cytotoxic effects of these compounds on a panel of 14 different human cancer cell lines including 6 hepatoma cell lines, based on the MTT method. Our results have shown that one of the xanthone derivatives which could be identified as Garcinone E has potent cytotoxic effect on all HCC cell lines as well as on the other gastric & lung cancer cell lines included in the screen.

   • Selon Abood WN (2020)

     Extrait mangostana (250 mg/kg and 500 mg/kg) with TAA showed a significant reduction in liver index a&hepatocyte proliferation with much lesser cell damage. mangostana peel on the histology, immunohistochemistry, a&biochemistry of thioacetamide (TAA) induced liver cirrhosis in Sprague Drawly (SD) rats.

   • Selon KOENIASARI SETIAWAN (s.d.)

     Extrait From the results of this study concluded that the mangosteen pericarp extracts could be a potent natural herbal product provide a promising hepatoprotective effect against lead acetate induced hepato toxicity in mice.

   • Selon Abuzaid AS (2016)

     Extrait The experimental study with rats was conducted for 9 weeks, with rats divided into 5 treatment groups which were normal (standard diet), control (high-calorie diet), dose 1 (MPEE 200 mg/kg b.w., high-calorie diet), dose 2 (MPEE 500 mg/kg b.w., high-calorie diet), & orlistat (orlistat 21.6 mg/kg b.w., high-calorie diet) groups. This study evaluated the preventive effect of mangosteen pericarp ethanolic extract (MPEE) on obesity by measuring body weight changes and fatty acid synthase (FAS) concentration in the adipose tissue and serum of monosodium glutamate and high-calorie diet-induced male Wistar rats.

   • Selon Abuzaid AS (s.d.)

     Extrait This study was conducted to evaluate the mangosteen ( Garcinia mangostana ) pericarp ethanolic extract (MPEE) properties in preventing obesity as well as its associated metabolic syndrome by analyzing the liver histology & measuring resistin, leptin, and adiponectin in the rats fed high-fat diet. The liver was collected for the histology analysis while the serum was collected for quantification of resistin, leptin, & adiponectin level by enzyme-linked immunosorbent assay (ELISA) method.

2. 2

   Glomerulosclérose du diabétique

   Partie usitée : Fruit (péricarpe).

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Widowati W (2018)

     Extrait MPE activity has correlates to inhibit the diabetic glomerulosclerosis condition & may increase mesangial cell proliferation.

   • Selon TAHER M (2016)

     Extrait mangostana pericarp ethanolic extract (GME) using the streptozotocin-induced (STZ) diabetic rats. Thus, the findings demonstrated that GME could be a potential candidate in the management of diabetes owing to its hypoglycaemic effect.

   • Selon Mohammed GA (2022)

     Extrait Garcinia mangostana (Clusiaceae) is a rich pool of metabolites with diversified bioactivities. These results could further provide new insight into the potential usage of GM as a functional food for regulating postprandial hyperglycemia via suppressing AA,.

   • Selon Nganlasom J (2008)

     Extrait leaves & Garcinia Mangostana Linn. hull on the healing of dermal wounds in diabetic rats.

   • Selon Palanisamy UD (2014)

     Extrait This was followed by the extracts from Syzygium cumini (leaf), Nephelium lappaceum, Syyzgium aqueum & Garcinia mangostana.(rind) Interestingly, it was observed that these extracts displayed activities comparable & at times higher than the commercial anti-glycemic drug; Acarbose, & the commercial grape seed extract. It is worthy to note that S cumini, has been shown to display anti-diabetic activities in sreptozotocin induced rat studies (Kumar et al., 2008).

3. 3

   Diabète mellitus de type II

   Partie usitée : Fruit (péricarpe). Profil pharmacologique documenté : Acarbose-like, Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon TAHER M (2016)

     Extrait mangostana pericarp ethanolic extract (GME) using the streptozotocin-induced (STZ) diabetic rats. Thus, the findings demonstrated that GME could be a potential candidate in the management of diabetes owing to its hypoglycaemic effect.

   • Selon Widowati W (2018)

     Extrait MPE activity has correlates to inhibit the diabetic glomerulosclerosis condition & may increase mesangial cell proliferation.

   • Selon Mohammed GA (2022)

     Extrait Garcinia mangostana (Clusiaceae) is a rich pool of metabolites with diversified bioactivities. These results could further provide new insight into the potential usage of GM as a functional food for regulating postprandial hyperglycemia via suppressing AA,.

   • Selon Nganlasom J (2008)

     Extrait leaves & Garcinia Mangostana Linn. hull on the healing of dermal wounds in diabetic rats.

   • Selon Palanisamy UD (2014)

     Extrait This was followed by the extracts from Syzygium cumini (leaf), Nephelium lappaceum, Syyzgium aqueum & Garcinia mangostana.(rind) Interestingly, it was observed that these extracts displayed activities comparable & at times higher than the commercial anti-glycemic drug; Acarbose, & the commercial grape seed extract. It is worthy to note that S cumini, has been shown to display anti-diabetic activities in sreptozotocin induced rat studies (Kumar et al., 2008).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.