Gardenia jasminoides (Jasmin du Cap) : vertus médicinales en extraction alcoolique

Gardenia jasminoides (Jasmin du Cap, Cape jasmine) — famille Rubiacées.

Synonymes scientifiques : Gardenia angusta –(L.) Merr., Genipa florida (L.) Baill, G grandiflora-Lour, Jasminum capense-Mill.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 9 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 141 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon LI N (2019)

     Extrait In vitro & in vivo studies have further identified the value of geniposide in a spectrum of preclinical models of diabetes mellitus (DM) & cardiovascular disorders. Geniposide, an iridoid glucoside, is a major component in the fruit of Gardenia jasminoides Ellis (Gardenia fruits).

   • Selon Wu S (2009)

     Extrait Geniposide is an iridoid glucoside extracted from Gardenia jasminoides Ellis fruits & has been reported to have a hypoglycemic effect. Results: Geniposide (200 & 400 mg/kg) significantly decreased the blood glucose, insulin & TG levels in diabetic mice in a dose-dependent manner.

   • Selon Zhou A (2023)

     Extrait To evaluate the effect of gardenia & its different extracts on type 2 diabetes mellitus (T2DM) in in vivo & in vitro experiments, the dried gardenia powder was extracted using 60% ethanol & eluted at different ethanol concentrations to obtain the corresponding purified fragments. For many centuries, Gardenia (Gardenia jasminoides Ellis) was highly valued as a food homologous Chinese herbal medicine with various bioactive compounds, including crocin I & geniposide.

   • Selon Liu H (2013)

     Extrait Numerous studies have confirmed that crocins & iridoid glycosides had effects of antioxidation, anti-inflammatory, anti-atherosclerosis, anti-ischemic brain injuries, anti-platelet aggregation, anti-hyperglycemia, anti-hyperlipidemia, anti-hypertension, & so on. The phytochemistry, cardiovascular pharmacology, toxicology, side effect, and further development prospects of Gardenia jasminoidesJ.

   • Selon LIU L (2022)

     Extrait Geniposide, as a novel iridoid glycoside compound, is an active natural product isolated from the herb Gardenia jasminoides Ellis (GJ) for the first time; it is also the main active component of GJ. Recent studies have found that geniposide has multiple pharmacological effects & biological activities, including hepatoprotective activity, an anti-osteoporosis effect, an antitumor effect, an anti-diabetic effect, ananti-myocardial dysfunction effect, a neuroprotective effect, & other protective effects.

2. 2

   Cancer : traitement adjuvant du carcinome gastrique

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Lv K (2021)

     Extrait Geniposide (GEN), one of the main iridoid glycosides in gardenia fruit, has been widely reported to have anti-cancer effects. Besides, Live/Dead staining, Hematoxylin-Eosin (H&E) staining & SEM evaluation were also conducted to estimate the anti-cancer effect of GEN in 2D & 3D cultures.

   • Selon Cho YS (2022)

     Extrait Genipin is a protein cross-linking agent extracted from Gardenia (Gardenia jasminoides Ellis) fruits. Genipin also increases the tissue inhibitors of matrix metalloproteases (MMP)-2, a kind of tumor promoter in a variety of cancers, as well as induces caspase-dependent apoptosis in in vitro & in vivo models.

   • Selon Wang X (2018)

     Extrait Gardenia jasminoides Ellis (GJE) is an herbal medicine possessing multiple pharmacological effects on human health with low toxicity. Importantly, the MTT results showed that exposure of breast cancer cells to the three compounds resulted in reduction of cell viability, demonstrating the cytotoxicity of the three compounds.

   • Selon LIU L (2022)

     Extrait Geniposide, as a novel iridoid glycoside compound, is an active natural product isolated from the herb Gardenia jasminoides Ellis (GJ) for the first time; it is also the main active component of GJ. Recent studies have found that geniposide has multiple pharmacological effects & biological activities, including hepatoprotective activity, an anti-osteoporosis effect, an antitumor effect, an anti-diabetic effect, ananti-myocardial dysfunction effect, a neuroprotective effect, & other protective effects.

   • Selon Sung YY (s.d.)

     Extrait Gardenia jasminoides has been used in traditional medicine for treatment of inflammation, edema, & dermaitis. Both GJE & GJE-EA reduced the expression of cytokines (interleukin [IL]-4, IL-6, & tumor necrosis factor-alpha) & adhesion molecules (intercellular adhesion molecule-1 & vascular cell adhesion molecule-1) in ear lesions.

3. 3

   Arthrose, arthrite, rhumatisme, oedème

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon LI N (2019)

     Extrait Geniposide has been experimentally proved to possess multiple pharmacological actions involving antioxidative stress, anti-inflammatory, antiapoptosis, antiangiogenesis, antiendoplasmic reticulum stress (ERS), etc. Geniposide, an iridoid glucoside, is a major component in the fruit of Gardenia jasminoides Ellis (Gardenia fruits).

   • Selon Fu Y (2012)

     Extrait Geniposide, a main iridoid glucoside component of gardenia fruit, has been known to exhibit antibacterial, anti-inflammatory & other important therapeutic activities. These results suggest that geniposide exerts an anti-inflammatory property by down-regulating the expression of TLR4 up-regulated by LPS.

   • Selon Chen L (2020)

     Extrait Various pharmacological properties, such as a beneficial effect on the nervous, cardiovascular & digestive systems, hepatoprotective activity, antidepressant activity, & anti-inflammatory activity, were also validated in vitro & in vivo. Gardenia jasminoides Ellis is a popular shrub in the Rubiaceae family.

   • Selon Koo HJ (2006)

     Extrait However, genipin possessed stronger anti-inflammatory activity than geniposide, as demonstrated by the results with carrageenan-induced rat paw edema, carrageenan-induced air pouch formation, & measurement of NO content in the exudates. GFE, genipin, & geniposide showed acute anti-inflammatory activities in carrageenan-induced rat paw edema.

   • Selon Lim H (2008)

     Extrait The fruits of Gardenia jasminoides have been previously reported to possess anti-inflammatory activity. All of these results suggest that genipin may contribute to anti-inflammatory activity of the fruits of GJ & an inhibitory action on prostaglandin & NO production is, at least, the part of anti-inflammatory mechanism of genipin.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.