Hibiscus syriacus (Rose de Syrie) : vertus médicinales en extraction alcoolique

Hibiscus syriacus (Rose de Syrie, Syrian Rose) — famille Malvacées.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 59 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome colorectal

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Xu XY (2022)

     Extrait In our previous study, Hibiscus syriacus leaf tissue was successfully cultivated in an optimized callus culture system, & subsequently extracted with 70% ethanol to prepare HS callus extract (HCE). The previous study suggested that the callus culture is useful method for obtaining the anti-inflammatory ingredients from HS Purpose In the present study, we aimed to investigate the effect of HCE on the colorectal cancer (CRC) & its underlying mechanism of action using HT-29 cells & thymus-deficient mice bearing HT-29 xenografts.

   • Selon Cheng Y (2008)

     Extrait syriacus (HS-AE) exhibited a better cytotoxic effect on lung cancer cells than its methanol extract (HS-ME) or water extract (HS-WE). These results indicate that HS-AE exerts significant & dose-dependent antiproliferative effects on cancer cells in vitro & in vivo, which prompts us to further evaluate and elucidate the bioactive component(s) of HS.

   • Selon CHAO Hh (2025)

     Extrait Hibiscus syriacus L. Cells exposed to Ang II were pretreated with HS extracts, & assays were performed to assess cell viability, reactive oxygen species (ROS) generation, protein synthesis, & secretion of inflammatory mediators, including tumor necrosis factor-alpha, interleukin 1β (IL-1β), & interleukin 6 (IL-6), as well as chemokine (CCL20) & HF-related biomarkers, such as brain natriuretic peptide (BNP) & endothelin-1.

   • Selon Hsu R (2015)

     Extrait Methods: This study screened Chinese herb Hibiscus syriacus extracts & identified a novel anti-cancer drug for patients with ER-negative breast cancer. Result: We found several triterpenoids including betulin (K02) & its derivatives (K03, K04, & K06) from HS inhibited human triple-negative breast cancer cell viability & migration but revealed smaller cytotoxic effects on normal mammalian epithelial cells.

   • Selon Yoo ID (1998)

     Extrait Three new naphthalene, designated as syriacusins A-C, were isolated from the root bark of Hibiscus syriacus. The first compound also showed cytotoxicity against some human cancer cell lines with an ED50 of 1.5-2.4 micrograms,.

2. 2

   Arthrose, arthrite, rhumatisme, oedème

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon KIM HN (2018)

     Extrait In this study, we evaluated the anti-inflammatory effect of 70% ethanol extracts from the root of HS (RHS-E70) & elucidated the potential signaling pathway in LPS-stimulated RAW264.7 cells. These results indicate that RHS-E70 may exert anti-inflammatory activity by inhibiting NF-κB & MAPK/ATF2 signaling.

   • Selon Lee CM (2023)

     Extrait This study aimed to investigate the anti-inflammatory effect of HSE in LPS-stimulated Raw 264.7 cells. Hibiscus syriacus L.

   • Selon Punasiya R (2014)

     Extrait It is used in tradition system of medicine & exibits diuretic, expectorant, stomachic, ophthalmic, antipyretic, anti-Inflammatory activity, antioxidant, demulcent, emollient, febrifuge, haemostatic & antifungal agent. Hibiscus syriacus Linn.

   • Selon Zhang RR (2020)

     Extrait The flower of Hibiscus syriacus Linn is a well-known traditional Chinese medicine (TCM) & health food in China, which has been used to treat dysentery, vaginal discharge, & hemorrhoids. In this study, five polyphenols (compounds 1-5) & five fatty acids (compounds 6-10) were isolated from the ethanol extract of the flower of HS.

   • Selon KOYUNCU M (2024)

     Extrait Studies have shown that Hibiscus species have anti-inflammatory, antibacterial, antifertility, antifungal, antioxidative, antihypertensive, & hypoglycaemic effects. The compounds with the highest ratios determined in the flower, seeds, leaves, & buds of Hibiscus syriacus L.

3. 3

   Stress oxydatif

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Molagoda I.M.N (2020)

     Extrait Collectively, our results suggested that, under H2O2-mediated oxidative stress conditions, PS sustained a normal level of mitochondrial membrane potential and ROS generation in HaCaT keratinocytes by activating the Nrf2/HO-1 axis, exerting cytoprotective effects against oxidative stress. In this study, we evaluated the cytoprotective effect of PS against H2O2-induced oxidative stress in HaCaT keratinocytes.

   • Selon Rassem HHA (2022)

     Extrait Scanning electron microscopy (SEM) was used to investigate the surface morphologies of raw powdered hibiscus flowers (not exposed to any pretreatment) & pretreated powdered hibiscus flowers (exposed to methanol absorption for 60 minutes prior to extraction). Therefore, the MAHD method is well-suited to extracting EOs from hibiscus flowers, & the resulting oil has the potential to provide significant therapeutic advantages,.

   • Selon JIN YQ (2019)

     Extrait JIN YQ et al, Composition analysis & antioxidant activity of polysaccharide from Hibiscus syriacus, Zhongguoo Zhong Yao Za Zhi, ;44(9):1822-8, 2019-Abstract; The flower of Hibiscus syriacus has good ornamental & edible-medicinal values. Among the tested varieties, polysaccharides of pink multiple petals flower & white multiple petals flower had the same molecular masses & monosaccharides composition, but the antioxidant activity of the polysaccharides of pink multiple petals flower was higher than that of the white flowers.

   • Selon Park Y (2022)

     Extrait As the national flower of Korea, the Hibiscus syriacus L. The petals produced high quantities of glucose, sucrose, & fumaric acid, with the highest antioxidant activity among the four units.

   • Selon Punasiya R (2014)

     Extrait Hibiscus syriacus Linn. It is used in tradition system of medicine & exibits diuretic, expectorant, stomachic, ophthalmic, antipyretic, anti-Inflammatory activity, antioxidant, demulcent, emollient, febrifuge, haemostatic & antifungal agent.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.