Holmskioldia sanguinea (Chapo chinwa -Chapeau chinois) : vertus médicinales en extraction alcoolique
Holmskioldia sanguinea (Chapo chinwa -Chapeau chinois) — famille Verbénacées.
Synonymes scientifiques : Holmskioldia rubra-Pers, Hastingia coccinea-Sm, H scandens-Roxb, Platinum rubrum-A Juss.
Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 2 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 16 références scientifiques pour cette espèce (détail intégral dans l’application).
Indications thérapeutiques en extraction alcoolique :
Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).
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Cancer : traitement adjuvant du lymphome
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon PAL M (2017)
Extrait Protective effect of Holmskioldia sanguinea leaf ethanolic extract has been investigated against Ehrlich ascites carcinoma (EAC) & Dalton’s ascites lymphoma (DAL) in Swiss albino mice to evaluate the possible mechanism of action. Holmskioldia sanguinea is a large climbing shrub found in the Himalayas at an altitude of 5,000 ft & preliminary investigation showed the excellent yield of andrographolide & subjected for the anticancer activity.
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Selon SATI R (2021)
Extrait Herb's anti-tumor & anti-cancer properties have generated significant interest. Holmskioldia sanguinea Retz.
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Selon PAL M (2017)
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Infection bactérienne : Escherichia coli, Staphylococcus aureus
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Ajaib M (2013)
Extrait In the present study, the various extracts of the plant Holmskioldia sanguinea Retz., were studied for their antioxidant & antimicrobial activities.
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Selon Ajaib M (2013)
D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.
Évolution de cette fiche publique
Sous le CTA · journal des mises à jour
~2 indications corrigées · −1 indication · +7 références · ~8 références corrigées · −1 référence
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
+7 références — afficher les textes
SAKR W et al, Establishment of an In vitro Rapid Direct Regeneration Protocol for Holmskioldia sanguinea Rare Flowering Plant Production, Agric & Food Sci, 2015-Abstract: This study was carried out in the Plant Tissue Culture Laboratory, Horticulture Research Institute, Agriculture Research Center, Ministry of Agriculture, during the period from 2011 to 2014. An efficient direct shoot regeneration micropropagation protocol has been established successfully for commercial in vitro propagation of Holmskioldia sanguinea, a rare plant with ornamental & medicinal values. The optimized sterilizat…
AjoutéeChaudhuri PK et al Antiinflammatory Activity of Holmskioldia sanguinea Extracts. Phytother Res, 10:357-8. 1996-Abstract: A carrageenin-induced oedema model was investigated to compare and elucidate the antiinflammatory effects of three fractions (CHCl3, n-BuOH & H2O) from the aerial parts of Holmskioldia sanguinea. The H2O (20 & 40 mg) &dn-BuOH (200 mg) fractions were found to be effective compared with standard hydrocortisone. The effective dose & lethal dose (LD50) value indicated that the extract was non-toxic.
AjoutéeSahney M et al, Wood anatomy of Holmskioldia sanguinea Retz: its adaptive & ecological significance. Taiwania 2017; 62(2):139-43.
AjoutéePal M et al, new source of andrographolide having potential biological activities. Jl of Bioequivalence & Bioavailability 2018; 10:65.
AjoutéeYadava RN et al, The Antibacterial Activity of Natural-Derived Flavonoids. Current Topics in Med Chem, 22(12), 1009-19, 2022-Abstract: A new flavone glycoside was isolated from ethanolic extract of stem parts of Holmskioldia sanguinea Retz. Its structure was characterized as 3,4′-dihydroxy-5,7-dimethoxyflavone-3-O-β-D-galactopyranosyl (1→4)-O-β-D-arabi-nopyranosyl-4′-O-α-L-rhamnopyranoside (1) by colour reactions, chemical degradation & spectroscopic analysis. Antibacterial activity of compound 1 was evaluated against various Gram positive & Gram-negative bacteria showing a significant effect.
AjoutéeSATI R et al, Antidiabetic Activity of Methanolic Leaf Extract of Holmskioldia Sanguinea in Streptozotocin-Nicotinamide Induced Type 2 Diabetic Rats, Jl of Diabetes & Metabolism, 13:7, 2022-Abstract: Holmskioldia sanguinea is a Sub-Himalayan plant that has been cultivated in the Americas, Europe, Indo-China, Asia-Pacific, & Southern Africa. The present study seeks to evaluate the methanolic leaf extract of S (MLEHS) for its anti-diabetic effect against streptozotocin–nicotinamide induced type 2 diabetic models in albino wistar rats. Phytochemical screening, oral glucose tolerance test and a…
AjoutéeChaudhari PK et al, Andrographolide & Other Constituents of Holmskioldia Sanguinea. Indian jl of Chem, 38B:632-4. 1999-Abstract: A new compound 27-methylnonaeicosanol 1 together with known lipids, lIiterpenoids, tlavonoids, bioacti ve andrographolide & neoandrographol ide have been isolated from Holmskioldia sanguinea & identi fi ed by thei r spectral & chemical study. This is the second natural occurrence of andrographolide and neoandrographolide, & their first occurrence from HS is of chemotaxollomic importance.
AjoutéeSATI R et al, PHYTOPHARMACOLOGY OF HOLMSKIOLDIA SANGUINEA RETZ.: A REVIEW, Inter Res Jl of Pharm,, 2021-Abstract: Holmskioldia sanguinea Retz. is a Sub-Himalayan plant that has been cultivated in the Americas, Europe, Indo-China, Asia-Pacific, & Southern Africa. It has been used traditionally to treat rheumatism & rheumatoid arthritis, dysentery, headaches, hypertension, boils, blain, ulcers, & gynaecological problems, as well as a blood purifying concoction. The botanical description of the plant, its phytochemical constituents, & its pharmacological activities are discussed, with an empha…
CorrigéeYadava RN et al, Allelopathic Effects of Leaves & Stems Extract of Holmskioldia sanguinea Retz. European jl Of Pharmaceut & Med Res, 5(11):619-21. 2018-Abdtract:
CorrigéeChaudhuri PK et al, Phytotoxic & Antimicrobial Constituents of Bacopa Monnieri & Holmskioldia sanguinea. Phytother Res, 18 (2):114-7. 2004-Abstract: The phytochemicals betulinic acid (1), wogonin (2) & oroxindin (3) isolated from the aerial parts of Bacopa monnieri & Holmskioldia sanguinea showed significant antifungal activity against the two fungi Alternaria alternata & Fusarium fusiformis. Inhibition of root growth germination of wheat seeds was observed for all three compounds which showed 100% inhibition at 10 micro g/mL. Compounds (1) & (2) showed potent inhibition of Alternaria alter…
CorrigéeAjaib M et al, Antioxidant & Antimicrobial Activities of an Ethnobotanically Important Plant Holmskioldia sanguinea Retz. of District Kotli, Azad Jammu & Kashmir. Pharmacology-online, 1:135-43. 2013-Abstract: In the present study, the various extracts of the plant Holmskioldia sanguinea Retz., were studied for their antioxidant & antimicrobial activities. Antioxidant potential of these extracts was evaluated by four methods: 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activity, total antioxidant activity, ferric reducing antioxidant power (FRAP) assay & ferric thiocyanate assay…
CorrigéePAL M et al, Antihepatotoxic effect of holmskioldia Sanguinea, Inter JL of Pharm & Pharmaceut Sci, 3:418-20, 2011-Abstract: The present study seeks to evaluate the alcoholic extract of aerial part of H.Sanguinea for its anti-hepatotoxic effect against carbon tetrachloride (CCI 4) induced hepatic damage in rats & phytochemical analysis.The phytochemical results depicted the presence of alkaloids, flavonoids, tannins, terpenoids, carbohydrate, glycosides & phenols.The activity was evaluated by using some biochemical parameters such as serum glutamate pyruvate transaminase (SGPT), alkaline pho…
CorrigéePAL M et al, Protective Effect of the Standardized Extract of Holmskioldia sanguinea on Tumor Bearing Mice, Inter Jl of Biotechnol & Bio prospect, 11:08, 2017-Abstract: Holmskioldia sanguinea is a large climbing shrub found in the Himalayas at an altitude of 5,000 ft & preliminary investigation showed the excellent yield of andrographolide & subjected for the anticancer activity. Protective effect of Holmskioldia sanguinea leaf ethanolic extract has been investigated against Ehrlich ascites carcinoma (EAC) & Dalton’s ascites lymphoma (DAL) in Swiss albino mice to evaluate the possible mecha…
CorrigéeHelfrich E et al, Iridoid glycosides & phenolic glycosides from Holmskioldia sanguinea. Phytochem, 50:619-27. 1999-Abstract: four new iridoids, 6-O-α-l-(2 ″-O-trans-cinnamoyl) rhamnopyranosylcatalpol, 6-O-α-l-(3 ″-O-trans-cinnamoyl) rhamnopyrano sylcatalpol, 6-O-α-l-(4 ″-O-trans-cinnamoyl) rhamno-pyranosyl-catalpol & 6-O-α-l-(4 ″-O-cis-feruloyl) rhamnopyranosylcatalpol, along with three known monoacyl rhamno-pyranosyl-catalpol derivatives have been isolated from the aerial parts of Holmskioldia sanguinea. Catalpol was identified by GC & GC–MS analysis. Three known phenolic glycosides, isola…
CorrigéePAL M et al, Antiinflammatory Activity of Holmskioldia sanguinea Extracts, Phytother Res, 1996-Abstract: A carrageenin‐induced oedema model was investigated to compare & elucidate the antiinflammatory effects of three fractions (CHCl3, n‐BuOH & H2O) from the aerial parts of Holmskioldia sanguinea. The H2O (20 & 40 mg) & n‐BuOH (200 mg) fractions were found to be effective compared with standard hydrocortisone. The effective dose & lethal dose (LD50) value indicated that the extract was non‐toxic.
CorrigéeYadava RN et al, Antibacterial Activity of a New Flavone Glycoside from the Stems of Holmskioldia sanguinea Retz. Asian J of Chem, 2019; 31(8):1815-8-Abstract: A new flavone glycoside was isolated from ethanolic extract of stem parts of Holmskioldia sanguinea Retz. Its structure was characterized as 3,4′-dihydroxy-5,7-dimethoxyflavone-3-O-β-D-galactopyranosyl (1→4)-O-β-D-arabinopyranosyl-4′-O-α-L-rhamnopyranoside (1) by colour reactions, chemical degradation & spectroscopic analysis. Antibacterial activity of compound 1 was evaluated against various Gram positive & Gram-negative bacteria sh…
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