Jatropha gossypifolia (Mèdsiyen-wouj) : vertus médicinales en extraction alcoolique

Jatropha gossypifolia (Mèdsiyen-wouj, Médicinier rouge, Red Healer) — famille Euphorbiaceae.

Synonymes scientifiques : Adenotropium globulifolium-(L)- Pohl, A. elegans-(Pohl), Jatropha glandulifera-Roxb, J elegans-(P)-Klot.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 9 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 74 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ogunma BG (2021)

     Extrait gossypifolia was subject to diuretics & hyperglycemic properties using established protocol of diuretic & diabetes test on the rat bladders emptied via mild compression in the pelvic region & gently pulling of their tails. gossypifolia leave extract on streptozotocin-induced diabetic rats.

   • Selon Singh H (2013)

     Extrait Decoction prepared from roots of Jatropha gossypifolia Linn is used in the treatment of diabetes & its associated complications. Petroleum ether (60-80°C), chloroform, methanol & aqueous extracts (250 & 500 mg/kg body weight) were orally administered to alloxan-induced diabetic mice for 7 days.

   • Selon Rahuja N (2013)

     Extrait The present study carried out to investigate the antidiabetic & hypolipidemic efficacy of active fractions (chloroform fraction of 95% ethanolic extract & butanol fraction of aqueous extract) of J Gossypifolia L.(stem) by measuring the status of blood glucose, serum insulin, carbohydrate metabolizing enzymes, lipid levels, renal & hepatic parameters on diabetic rats. gossypifolia L.(stem), significantly reduced blood glucose levels of diabetic rats while in multiple dose studies, chloroform fraction of 95% ethanolic extract restored the elevated biochemical parameters significantly to the near normal level in type 2 diabetic rats when compared with standard drug Metformin (100 mg/kg) but butanol fraction of aqueous extract did not show any marked effect.

   • Selon Granados S (2015)

     Extrait (Euphorbiaceae) is a plant widely used in the treatment of type 2 diabetes mellitus (T2DM), but there are few scientific reports validating its activity in this area. Jatropha gossypifolia L.

   • Selon Sabandar C.W (2013)

     Extrait The genus Jatropha (Euphorbiaceae) comprises of about 170 species of woody trees, shrubs, subshrubs or herbs in the seasonally dry tropics of the Old & the New World.

2. 2

   Hepatite, cirrhose, steatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Akinloye OA (2015)

     Extrait gossypifolia may not have A protective role against chromosomal & liver damage in KBrO3-induced toxicity, but complicating effects. gossypifolia have been reported to have several medicinal values, including potential Anticancer & antiinflammatory properties.

   • Selon Jain S (2015)

     Extrait The results of this study strongly indicate that J gossypifolia leaves have potent hepatoprotective action against carbon tetrachloride induced hepatic damage in rats. Jatropha gossypifolia has been traditionally used in the Ayurvedic system of medicine as a chief ingredient of many polyherbal formulations as antioxidant.

   • Selon dos Reis JM (2013)

     Extrait The leaves & fruits of J gossypifolia were evaluated for their chemical composition.

   • Selon Hosamani KM (2008)

     Extrait Jatropha gossypifolia & Hevea brasiliensis seed oils were found to contain 18.5% and 18.0% of 12-hydroxyoctadec-cis-9-enoic acid (ricinoleic acid), respectively.

   • Selon Rahuja N (2013)

     Extrait The present study carried out to investigate the antidiabetic & hypolipidemic efficacy of active fractions (chloroform fraction of 95% ethanolic extract & butanol fraction of aqueous extract) of J Gossypifolia L.(stem) by measuring the status of blood glucose, serum insulin, carbohydrate metabolizing enzymes, lipid levels, renal & hepatic parameters on diabetic rats. gossypifolia L.(stem), significantly reduced blood glucose levels of diabetic rats while in multiple dose studies, chloroform fraction of 95% ethanolic extract restored the elevated biochemical parameters significantly to the near normal level in type 2 diabetic rats when compared with standard drug Metformin (100 mg/kg) but butanol fraction of aqueous extract did not show any marked effect.

3. 3

   HTA, oedeme, rétention hydrique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2014)

     Extrait Pharmacological studies have demonstrated significant action of different extracts and/or isolated compounds as antimicrobial, anti-inflammatory, antidiarrheal, antihypertensive, & anticancer agents, among others, supporting some of its popular uses. Jatropha gossypifolia L.

   • Selon Panda BB (2009)

     Extrait We have determined the anti-inflammatory and analgesic activity of methanolic and petroleum ether extracts of dried aerial parts of Jatropha gossypifolia by oral administration at doses of 100 and 200 mg/kg/day of body weight to healthy animals. The present study was done to investigate the anti-inflammatory & analgesic effect of methanolic & petroleum ether extracts of Jatropha gossypifolia Linn.

   • Selon Xavier-Santos JB (2018)

     Extrait gossypiifolia showed significant acute anti-inflammatory activity in ear edema model, & this activity was significantly increased when equivalent amounts of extract were applied incorporated in the developed poloxamer gels. gossypiifolia extract was developed, physicochemically characterized & evaluated in the same model of inflammation to assess whether the extract incorporation in gel would affect its anti-inflammatory potential.

   • Selon Yerramsetty N (2013)

     Extrait The present study aimed to evaluate the anti-inflammatory activity of aqueous & alcoholic extract of JG leaves by in vitro HRBC membrane stabilization method Results: The in vitro method showed significant anti-inflammatory property of different extracts tested.

   • Selon Rani B (2011)

     Extrait Methanolic extract of Jatropha gossypifolia leaves showed systemic & significant anti-inflammatory activity in acute carrageenan-induced rat paw edema & chronic cotton pellet induced granuloma formation after oral treatment for 7 days in Wistar rats. Anti-inflammatory activity might be due to effects on several mediators & arachidonic granular tissue formation & leukocyte migration from vessels.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.