Kalantchoe pinnata (Zèb-mal-têt) : vertus médicinales en extraction alcoolique

Kalantchoe pinnata (Zèb-mal-têt, tonbé-lévé, Farin Cho) — famille Crassulacées.

Synonymes scientifiques : Cotylédon pinnata-Lam, Bryophyllum pinnatum-(Lam)-Oken, B. Calycinum-Salisb.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 22 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 109 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Tige.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Matthew S (s.d.)

     Extrait The main objective of present work is to find out good pharmacological activities in herbal source with their preliminary phytochemical study, & also it is aimed to investigate Anti-diabetic activity of ethanolic & aqueous extracts of dried stem of plant Kalanchoe pinnata against CNS-Depressant activity in rats.

   • Selon Goyal P (2013)

     Extrait pinnata against alloxan-induced diabetes in rats. pinnata decreased the blood glucose level of rats affected by diabetes.

   • Selon Matthew S (s.d.)

     Extrait The main objective of present work is found out good pharmacological activities in herbal source with their preliminary phytochemical study, and also it is aimed to investigate Anti-Diabetic activity of ethanolic & aqueous extracts of dried stem of plant Kalanchoe pinnata (LAM.) PERS against alloxan induced diabetes in rats. The alcoholic extract of dried stem of K pinnata shows the significant inhibition activity of α- amylase enzyme as compared to aqueous extract.

   • Selon Bandhari R (2021)

     Extrait This investigation was designed to explore the result shown by methanolic extract of Garuga pinnata bark & Bryophyllum pinnatum leaves, on cognitive power & retention of the memory in experimental mice along with quantification of phenolic compounds & DPPH radicals neutralizing capacity.

   • Selon Ramon P (2023)

     Extrait pinnata treatment (400 µg/mL) alone significantly increased catalase (CAT) activity for non-diabetic & diabetic human skeletal muscle myoblasts & a H2O2-stress-induced human skeletal muscle myoblast cell line, while significantly lowering malondialdehyde (MDA) levels. In this study, the compound composition of Kalanchoe Pinnata & the effects of combined preparations of KP & metformin on antioxidant activity in human skeletal muscle myoblasts (HSMMs) & human diabetic skeletal muscle myoblasts (DHSMMs) were investigated.

2. 2

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Feuille. Association synergique mentionnée : Cyperus rotundus.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Yadav NP (2003)

     Extrait The juice of the leaves & the ethanolic extract of the marc left after expressing the juice were studied in rats against CCl4-induced hepatotoxicity. The test material was found effective as hepatoprotective as evidenced by in vitro, in vivo & histopathological studies.

   • Selon Guruswamy K (2010)

     Extrait The ethanolic extracts of the polyherbal medicinal plants (Asteracantha longifolia, Cyperus rotundus & Bryophyllum pinnatum) were evaluated for hepatoprotective activity in carbon tetrachloride induced liver damage in rats. exhibited a significant protective effect by lowering serum and liver activities of aspartate transaminase (AST), alanine transaminase (ALT), acid phosphatase (ACP), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), serum Bilirubin, serum cholesterol & serum total protein when compared with standard silymarin.

   • Selon Saravanan V (2021)

     Extrait Histopathology of the Liver, Heart & Kidney did not show any remarkable lesions that could be related to the administration of the leaf extract. Kalanchoe pinnata is a perennial plant that is widely used in the folklore treatment of kidney & gall stones & urinary insufficiency.

   • Selon FAUNDES-Gandolfo N (2024)

     Extrait pinnata), a succulent plant native to tropical regions, are used as a medicinal alternative against cancer in several countries worldwide; however, its therapeutic potential to fight cancer has been little addressed.

3. 3

   Cancer : traitement adjuvant de l’adénocarcinome mammaire & colorectal

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon HERNANDEZ-CABLLERO MA (2022)

     Extrait This study aimed to identify the bioactive ingredients in Kalanchoe pinnata, a succulent herb with ethnomedical applications for several diseases, including cancer, & reveal its anticancer mechanisms through a molecular approach. pinnata as an adjuvant in cancer treatment.

   • Selon FAUNDES-Gandolfo N (2024)

     Extrait pinnata), a succulent plant native to tropical regions, are used as a medicinal alternative against cancer in several countries worldwide; however, its therapeutic potential to fight cancer has been little addressed. Human cancer (MCF-7, PC-3, HT-29) & normal colon (CoN) cell lines were treated with different concentrations of KP leaf ethanolic extract, & the changes in cell proliferation (sulforhodamine B assay), caspases activity (FITC-VAD-FMK reporter), mitochondrial membrane potential (MMP, rhodamine 123 assay), chromatin condensation/fragmentation (Hoechst 33342 stain), & ROS generation (DCFH2 probe assay) were assessed.

   • Selon Ramon P (2021)

     Extrait Results also indicate that combinatorial preparations of KP may modulate immune responses by significantly upregulating proinflammatory markers, interleukin (IL) 2, & tumor necrosis factor-alpha, & upregulating the anti-inflammatory marker, IL-10, in HSMM & DHSMM cells. In this study, combined preparations of Kalanchoe pinnata & metformin were investigated to determine the effects on inflammatory activity in human skeletal muscle myoblasts (HSMMs) & human diabetic skeletal muscle myoblasts (DHSMMs).

   • Selon Mahata S (2012)

     Extrait Mahata S et al, Anticancer property of Bryophyllum pinnata (Lam.) Oken leaf on human cervical cancer cells.

   • Selon Stefanowicz-Hajduk J (2020)

     Extrait blossfeldiana ethanol extract did not show the presence of these compounds, Conclusion: K blossfeldiana ethanol extract is a potential candidate for cancer & bacterial infection treatment. Cytotoxicity tests were performed on human cancer cell lines – HeLa, SKOV-3, MCF-7, & A375 by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay & Real-Time Cell Analysis system.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.