Laportea aestuans (Zôti) : vertus médicinales en extraction alcoolique

Laportea aestuans (Zôti, Zouti Brilant, Ortie, Ortie brulante, Stinging nettle) — famille Urticacées.

Synonymes scientifiques : Urtica aestuans-L, Fleurya aestuans-(L)-Gaudich.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 11 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 42 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer: traitement adjuvant de la leucémie

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Aladesanmi A.J (2020)

     Extrait The study investigated eight Nigerian medicinal plants: Artocarpus communis fruit (Ac-F), Cassia sieberiana root bark (Cs-R), Eugenia uniflora leaf (Eu-L), Hibiscus rosa-sinensis flower (Hr-F), Laportea aestuans aerial part (La-A), Massularia acuminata stem bark (Ma-S), Trichilla heudelotii leaf (Th-L), & Xylopia aethiopica fruit (Xa-F), for anticancer activity. The results showed a concentration dependent decrease in cancer cell viability & cytotoxicity of four of the extracts, namely MA stem bark (Ma-S), XA fruit (Xa-F (La-A),), L aestuans aerial part (XP) & E uniflora leaf (Eu-L).

   • Selon TIJANI AS (2022)

     Extrait Laportea aestuans (Urticaceae) plant is widely distributed in tropical rain forests & used as remedial agent for various diseases in Nigeria by herbal practitioners. This study investigated the cytoprotective effect of pretreatment with methanol extract of L aestuans (MELA) for 7 days on ethanol-induced gastric ulcer in male Wistar rats using cimetidine as a standard drug.

   • Selon ODO EC (2024)

     Extrait This study evaluated the ameliorative effect of Hydrocotyle verticillata (H.v) & Laportea aestuans (L.a) leaves extracts on hematological, biochemical & histopathological indices on 7,12-dimethylbenz(α) anthracene (DMBA) induced-leukemia in Wistar rats. HV & LA have shown to possess hepato-renal protective effect & modulated hematological indices in induced-leukemia,.

   • Selon ODO EC (2022)

     Extrait Leukemia has been linked to mRNA expression of Sphingosine-1-phosphate receptor-1(S1PR-1) & considering multiple reports on the roles of phytochemicals in Hydrocotyle verticillata & Laportea aestuans, this study aims to evaluate the effects of administration of ethanol extracts of the 2 plants in regulation of mRNA expression of S1PR-1 in leukemia induced by 7,12-dimethylbenz(α) anthracene (DMBA) in rats. Conclusion: This outcome of the present study has shown that the plant extracts upregulated the mRNA expression of S1PR1 in a leukemic rat hence can be used as an adjunct in leukemia treatment,.

2. 2

   Infection bacterienne : Escherichia coli, Salmonella Typhi & Staphylococcus aureus

   Partie usitée : Feuille. Profil pharmacologique documenté : Chloramphenicol-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Siahaya EV (2025)

     Extrait This study aims to analyze the comparison between Laportea decumana & Laportea aestuans, focusing on the two main aspects, phytochemical screening & antibacterial activity. The antibacterial test using agar diffusion method shows that both extracts inhibited the growth of pure strains of E.

   • Selon Simaremare ES (2017)

     Extrait The aim of the study was to determine the activity of antibacteria of LA against Escherichia coli, Staphylococcus aureus & Salmonella typhi. Daun gatal (Laportea aestuans) is an indigenous plant of Papua hich has been widely used for pain relief as traditional medication in the local community.

   • Selon OLEYODE G (2011)

     Extrait The oils showed appreciable antimicrobial activity -against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhi, Candida albicans, Rhizopus stolon, Aspergillus niger & Penicillium notatum at 200mg/ml when compared to standards; gentamicin for bacteria & tioconazole for fungi. The colourless essential oils obtained by hydro-distillation from the whole plant of Laportea aestuans (Gaud) were analysed by GC & GC/MS.

   • Selon Oloyede GK (2016)

     Extrait Oloyede GK et al, Toxicity, antimicrobial & antioxidant activities of methyl salicylate dominated essential oils of Laportea aestuans (Gaud).

   • Selon KAMBU J (2024)

     Extrait Penelitian ini bertujuan mengevaluasi aktivitas antibakteri ekstrak etanol kedua spesies terhadap Staphylococcus aureus & Escherichia coli menggunakan metode difusi cakram dan bioautografi. Laportea interrupta dan Laportea aestuans, dikenal sebagai daun gatal, merupakan tanaman asli Papua yang digunakan secara tradisional untuk meredakan nyeri & pegal melalui aplikasi topikal.

3. 3

   Arthrose, arthrite, rhumatisme, oedeme

   Partie usitée : Feuille. Profil pharmacologique documenté : Diclofenac-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ashidi J (2017)

     Extrait In traditional medicine, Laportea aestuans (LA) is used in treatment of several ailments including pain & inflammatory conditions. This study evaluates the analgesic & anti-inflammatory potential of the ethanol extract of the leaves of LA using hot-plate induced analgesia and carrageenan-induced acute inflammatory model in Albino Wistar rats (120g-160g).

   • Selon Simaremare ES (2018)

     Extrait Then ELA was evaluated analgesic with tail flick test & anti-inflammatory effect with carrageen-induced paw edema with 0.3 g/kg, 0.6g/kg, & 1.2g/kg dose on white male rat. Laportea aestuans (Linn.) Chew as original plant from Papua has been using for pain relief as traditional medication in the local community widely.

   • Selon Nwafor CC (2022)

     Extrait Acute inflammation was produced in the anti-inflammatory trial groups by injecting 0.1 ml of egg albumin sub-plantarly into the left hind paw. The goal of this study is to see if hydroethanolic extract of Fleurya aestuans can reduce pyrexia & inflammation in Wistar rats.

   • Selon Onadeko A (2021)

     Extrait Non-steroidal anti-inflammatory drugs (NSAIDs) are connected with the generation of free radicals & one of its adverse effects is gastric ulceration. In conclusion, the ethanoic extract of LA can be said to be used as an anti-ulcerogenic agent against aspirin-induced gastric ulcer which is due to the presence of phytochemicals in the plant,.

   • Selon Akinwande O (2021)

     Extrait toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) are being reported with its diverse effect in the host resulting in ulcerations. In conclusion, the ethanoic extract of LE can be said to be used therapeutically against aspirin-induced gastric ulcer which is due to the presence of bioactive compounds in the plant as an anti-ulcerogenic agent against aspirin-induced gastric ulcer which is due to the presence of phytochemicals in the plant.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.