Leucaena leucocephala (Tamaren-makak) : vertus médicinales en extraction alcoolique

Leucaena leucocephala (Tamaren-makak, Tamaren-bata, Makata-bous, Monval, Zakadi, Tamarin-à-macaque, Tamarin-batârd, Macata-à-bourse) — famille Mimosacées.

Synonymes scientifiques : Acacia glauca-Willd, Mimosa. glauca-L, M. leucocephala-Lam, M. Leucocephala leuco-(Wiss)-Benth.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 133 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Chowtivannakul P (2016)

     Extrait Leucaena leucocephala (Lam.) de Wit has been used for various purposes such as treatment of stomach diseases, facilitation of abortion, contraception and the treatment of diabetes. Antidiabetic activity testing was carried out by giving LLSE at an oral dose of 250 mg/kg body weight to streptozotocin-induced diabetic rats daily for 6 wk.

   • Selon Xu Y (2018)

     Extrait We investigated the constituents of Leucaena leucocephala foliage collected from Guangdong province in China & isolated 17 diverse flavonoids (1–17), including flavones (5–9, 11, & 12), flavonols (1, 10, & 16), flavanone 4, flavanonol 15, & flavonol glycosides (2, 3, 13, 14, & 17). pHRE-Luc inductive activity to mimic the activation of erythropoietin (EPO) gene, anti-inflammatory, antidiabetic, & antioxidant activities of isolated flavonoids (1–17) were evaluated.

   • Selon Talubmook C (2013)

     Extrait Talubmook C et al, Hypoglycemic & Hypolipidemic Properties of Leaf Extracts from Phyllanthus acidus (L.) Skeels., Leucaena leucocephala (Lam.) de Wit & Psidium guajava (L.) in Streptozotocin-Induced Diabetic Rats, Int of Bio-Sciences, 25(2) :2013-Abstract— Star gooseberry Phyllanthus acidus (L.) Skeels, lead tree Leucaena leucocephala (Lam.) de Wit & guava Psidium guajava (L.) are commonly well known plants & have been widely used in folk medicine for the treatment of many diseases in Thailand. The results revealed, that the extracts significantly (p<0.05) decreased blood glucose level, total cholesterol (TC), triglyceride, (TG), low density lipoprotein (LDL), blood urea nitrogen (BUN) & creatinine but increased high density lipoprotein (HDL) & serum insulin in the diabetic treated rats.

   • Selon Sarma P (2024)

     Extrait Leucaena leucocephala. (Lam.) de Wit, a traditional medicinal plant, has been reported among the ethnic communities of Mexico, Indonesia, China, & India for the treatment of diabetes, obesity, & related complications.

   • Selon Chowtivannakul S (2012)

     Extrait Chowtivannakul S et al, Antioxidant & antidiabetic activities of leaf & seed extracts from Leucaena leucocephala (Lam.) de Wit.

2. 2

   Cancer : chemoprevention (action antimutagenique)

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Chatchanayuenyong R (2020)

     Extrait Several medicinal plants have recently increased in the involvement of chemotherapeutic drugs development, including Leucaena leucocephala & Dolichandrone serrulata. serrulata ethanolic extracts (125–500 μg/ml) have been proposed in this study of possessing antioxidant & anti-migration activity, as well as the ability in induce cancer cell death.

   • Selon RATIKORN C (2013)

     Extrait Leucaena leucocephala has been reported of possessing antioxidant, antidiabetic & anticholinesterase activity; as well as the toxic substance called mimosine. leucocephala in endothelium functions & has been found to have an appropriate concentration at 0.05 mg/mL in reducing oxidative stress condition in impaired fasting blood glucose patients.

   • Selon Chung HH (2017)

     Extrait These data indicate that LL could be a potent therapeutic agent for the prevention & treatment of oral cancer & a prominent plant source for anticancer research in the future. leucocephala extract on SCC-9 & SAS oral cancer cells & examined the potential inhibitory mechanisms involved.

   • Selon She LC (2017)

     Extrait The objective of this study was to evaluate the anti-cancer effects of compounds obtained from the plant Leucaena leucocephala in human chronic myelogenous leukaemia, prostate, liver, tongue, lung, melanoma, gastric & colon adenocarcinoma cancer cell lines. These results indicated that investigation on the anti-proliferation, anti-migration & anti-invasion effects of components from L leucocephala,.

   • Selon Inglum P (2011)

     Extrait A new lectin, leucocephalin was evaluated in the seed extracts of the four strains of Leucaena leucocephala. The result suggested the potential application of leucocephalin as a chemopreventive or anticancer agent.

3. 3

   Diarrhée

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hussein S (2020)

     Extrait This study was investigating the antidiarrheal activity of the ethanol extracts of Leucaena leucocephala (Lam) de Wit seeds induced by oleum ricini & intestinal transit methods for rats. leucocephala seed extract at doses of 100, 200, & 400 mg/kg bw has been shown to significantly delay the onset of diarrhea, reduce diarrhea frequency, stool weight & duration of diarrhea compared with Na CMC as a negative control (p < 0.05).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.