Mirabilis jalapa (Bêl-di-nui) : vertus médicinales en extraction alcoolique

Mirabilis jalapa (Bêl-di-nui, Belle-de-nuit, Night-beauty) — famille Nyctaginacées.

Synonymes scientifiques : Mirabilis ambigua-T, M J, var Lindl-(S)-Cory, M Linderheimiri-(S)-Shin, Nyctago jalapae-(L)-DC.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 15 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 103 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Racine. Profil pharmacologique documenté : Glibenclamide-like, Rosiglitazone-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sarkar P (2011)

     Extrait This study was designed to investigate the Anti-diabetic activity of an ethanolic extract of the root of Mirabilis Jalapa which is widely being used in Himalayan region as a traditional treatment for diabetic mellitus. Ethanolic extract of Mirabilis Jalapa (EEMJ) (10mg/kg & 20mg/kg) were administered as a single dose per day to the streptozotocin-induced diabetic rats for 12 days.

   • Selon Jiang Ming-Jin (s.d.)

     Extrait Rats were divided into following groups: normal group,model group, ethanolic extract of MJ roots group(1,2,4 g · kg-1) & rosiglitazone group(4 mg · kg-1).After 8-weeks treatment,fasting blood glucose( FBG), hemoglobin(HbAlC), total cholesterol(TC), triglyceride(TG), serum insulin(FINS) levels & glycogen contents in liver & skeletal muscle were assayed. To investigate the effects of ethanolic extract of Mirabilis jalapa roots on glucolipid metabolization in diabetic rats.

   • Selon Zhou JY (2012)

     Extrait The present study investigated the insulin sensitivity, hypoglycemic, & hypolipidemic activities of ethanolic extract of Mirabilis jalapa L. Both after & before induction of diabetes, repeated administration with 4, 8 g/kg EEM continually lowered blood glucose level, decreased serum insulin level & improved insulin sensitivity index, & lowered serum total cholesterol, triglyceride levels & triglyceride content in liver & skeletal muscle, & increased glycogen content in these tissues; but repeated administration had no influence on those indexes of normal mice.

   • Selon Luo LS (s.d.)

     Extrait To study the effect of the extract of Mirabilis jalapa root on the blood glucose of normal mice & diabetes mice induced by adrenaline & glucose. Methods:High blood glucose model mice were made by 160μg/kg adrenaline solution & 10% glucose solution.The hypoglycemic effect of the extract of MJ root on the blood glucose of the model mice was observed.Results:The low,middle & high dose of the extract of MJ root had no effect on the normal mice (P0.05), but the high dose of the extract could lower the blood glucose levels of the adrenalin & high blood glucose mice( P0.05).

   • Selon Rout S (2012)

     Extrait Results: The fasting blood glucose level in normoglycemic, hyperglycemic and in oral glucose tolerance test, showed a significant (p<0.05) decrease at defined time points, while the observed biochemical & physical parameters showed a good agreement with antihyperglycemic property of the extract. Antidiabetic potential was assessed by the measurement of fasting blood glucose, Serum Lipid Profile (total cholesterol, triglycerides), physical parameters (body weight, food & water intake) & Oral Glucose tolerance test.

2. 2

   Hépatopathies : hépatite, cirrhose, stéatose hépatique, normalisation des paramètres sériques , troubles hépatiques liés à la prise de medications antituberculeuse

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Basini J (2013)

     Extrait The present study was undertaken for investigating the protective effect of ethanolic extract of Mirabilis Jalapa leaves on anti-tubercular drugs induced hepatotoxicity. Conclusion: The result of the present study was indicated that MJ showed hepatoprotective effect on hepatotoxicity induced by anti-tubercular drugs.

   • Selon Ahmad MS (1984)

     Extrait A fatty acid, found as a minor component in the seed oil of Mirabilis jalapa, is shown to be the hitherto unknown 8-hydroxyoctadeca-cis-11,14-dienoic acid.

   • Selon Zhou JY (2012)

     Extrait The present study investigated the insulin sensitivity, hypoglycemic, & hypolipidemic activities of ethanolic extract of Mirabilis jalapa L. Both after & before induction of diabetes, repeated administration with 4, 8 g/kg EEM continually lowered blood glucose level, decreased serum insulin level & improved insulin sensitivity index, & lowered serum total cholesterol, triglyceride levels & triglyceride content in liver & skeletal muscle, & increased glycogen content in these tissues; but repeated administration had no influence on those indexes of normal mice.

   • Selon Jiang Ming-Jin (s.d.)

     Extrait Rats were divided into following groups: normal group,model group, ethanolic extract of MJ roots group(1,2,4 g · kg-1) & rosiglitazone group(4 mg · kg-1).After 8-weeks treatment,fasting blood glucose( FBG), hemoglobin(HbAlC), total cholesterol(TC), triglyceride(TG), serum insulin(FINS) levels & glycogen contents in liver & skeletal muscle were assayed. To investigate the effects of ethanolic extract of Mirabilis jalapa roots on glucolipid metabolization in diabetic rats.

   • Selon Rout S (2012)

     Extrait Antidiabetic potential was assessed by the measurement of fasting blood glucose, Serum Lipid Profile (total cholesterol, triglycerides), physical parameters (body weight, food & water intake) & Oral Glucose tolerance test. To evaluate the antihyperglycemic activity of hydro-alcoholic extract of aerial parts of Mirabilis jalapa for its purported use in diabetes.

3. 3

   Infection bacterienne: Vibrio cholerae, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Salmonella typhi & Serratia marcescens

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sankar NS (2015)

     Extrait against seven pathogenic bacteria such as Vibrio cholerae, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Salmonella typhi & Serratia maecescence, Among the water, methanol & ethanol extract, the ethanolic extract showed maximum activity. Antibacterial activity & phytochemical analysis were carried out in Mirabilis jalapa L.

   • Selon MUHSINA CP (2017)

     Extrait Antimicrobial activity of Mirabilis Jalapa leaf extracts were determined against the pathogens such as Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans. Among all the solvents of Mirabilis Jalapa, the ethanolic leaf extract showed excellent activity against Staphylococcus aureus (36mm) and moderately against Candida albicans (29mm).

   • Selon Salman SM (2015)

     Extrait The antimicrobial activities of ethanolic extract of MJ were investigated against four strains of bacteria, Salmonella typhi, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. The plants extract show high sensitivity against Pseudomonas aeruginosa & least sensitivity against Staphylococcus aureus.

   • Selon Ali Saukat (2015)

     Extrait The antimicrobial activities of ethanolic extract of MJ were investigated against four strains of bacteria, Salmonella typhi, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa. The main aims of this study was to identify all the bio active compounds present in the Mirabilis jalapa plant (leaves & stem) qualitatively by using four different solvent system (water, hexane, ethanol, & ethyl acetate).

   • Selon Oladunmoye KM (2007)

     Extrait The ethanolic extract of the leaf of Mirabilis jalapa was tested for antimicrobial activity against five pathogenic bacterial strains: Escherichia coli, Staphylococcus aureus, Salmonella typhi, Bacillus cereus & Klebsiella pneumoniae. The isolates producing the toxins were identified as Pseudomonas sp., Acinetobacter sp., Corynebacterium sp.,Actinomyces sp., Clostridium sp., Bacillus sp., Shigella sp., Proteus sp.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.