Momordica charantia (Pawoka) : vertus médicinales en extraction alcoolique

Momordica charantia (Pawoka) — famille Cucurbitacées.

Synonymes scientifiques : Cucumis argyi-H. Lèv, Momordica chinensis-Spreng, M sinensis-Spreng, Sycos fauriel-H. Lèv.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 34 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 262 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cataracte associée au diabète mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Srivastava S (1988)

     Extrait was studied in Charles Foster rats of both sexes in respect of its dose-response hypoglycemia and at maximal effective dose, its influence on the development of diabetic cataract. Alloxan (120 mg/kg s.c./rat, single dose) diabetic rats with 7150 mg% of blood sugar were classified into four groups (n=10) wherein two were control and the rest were test groups).

   • Selon Wardani BPN (2021)

     Extrait Hyperglycemia is a condition of excessive blood glucose in blood plasma caused by damage to the pancreatic beta-cell structure that causes impaired insulin secretion. The conclusion of this study was MC & AB ethanol extract with a treatment of 40 mg.kg-1 BW can suppress IL-1b pro-inflammatory cytokines in hyperglycemic mice models, but has not been able to reduce the expression of IL-6 pro-inflammatory cytokines.

   • Selon Yakaiah V (2013)

     Extrait to investigate the anti-diabetic effect of the bitter melon on Alloxan induced diabetes in experimental animals (rabbits. Materials & Methods: the alcohol extract of whole fruit was tested for its efficacy in Alloxan (150mg/kg induced diabetic rabbit.

   • Selon BISWAS AR (1991)

     Extrait In the Ayurvedic system of medicine, the fruits of this plant have been traditionally used for the treatment of diabetes mellitus and hepatic disorders & for pain relief in gout & rheumatism (Satapathy et al., 19871.In the present study, an attempt has been made to evaluate the analgesic activity of this plant in animals. charantia (authenticated by the Department of Botany of our Institute), collected during the month of December, were shade dried at room temperature for four weeks before the seeds were separated out.

   • Selon Hussain TS (2014)

     Extrait To investigate hypoglycaemic, hypolipidaemic & pancreatic beta cell regeneration activities of Momordica charantia fruits. Alloxan-induced diabetic rabbits were treated with methanolic & ethanolic MC extract.

2. 2

   Traitement adjuvant du pied diabétique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Rosyid FN (2018)

     Extrait Diabetic foot ulcer (DFU) is among the many complications of diabetes & it takes a very long period of time to heal. The aim & objective of this study is to assess the effect of bitter melon leaves extracts on serum TNF-α levels & improvement of diabetic foot ulcers.

   • Selon KIM SK (2020)

     Extrait charantia as an adjuvant treatment in patients with type 2 diabetes. Momordica charantia (bitter melon) is widely used for its glucose-lowering effects.

   • Selon Offor U (2018)

     Extrait In conclusion MC extract administration improved blood glucose levels, restored renal histology, reinstate renal function, reduce body weight loss & restores hyperglycemia. charantia in rats following treatment with highly active antiretroviral therapy (HAART) regimen triplavar.

   • Selon Srivastava S (1988)

     Extrait Alloxan (120 mg/kg s.c./rat, single dose) diabetic rats with 7150 mg% of blood sugar were classified into four groups (n=10) wherein two were control and the rest were test groups). was studied in Charles Foster rats of both sexes in respect of its dose-response hypoglycemia and at maximal effective dose, its influence on the development of diabetic cataract.

   • Selon Malik ZA (2013)

     Extrait Malik ZA et al, Attenuation of experimentally induced diabetic neuropathy in association with reduced oxidative-nitrosative stress by chronic administration of < i> Momordica charantia & lt;/i&gt, Adv in Bioscience & Biotechnol, 04: 356-63, 2013,.

3. 3

   Diabète mellitus de type II (Acarbose/Glibenclamide-like uniquement en association synergique)

   Partie usitée : Fruit. Association synergique mentionnée : Momordica dioica-fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Wardani BPN (2021)

     Extrait This study aimed to investigate the combination of Bitter Melon & Star Fruit ethanol extract (SBME) on pro-inflammatory cytokines production in hyperglycemic albino mice models. Hyperglycemia is a condition of excessive blood glucose in blood plasma caused by damage to the pancreatic beta-cell structure that causes impaired insulin secretion.

   • Selon Savula J (2012)

     Extrait Momordica charantia is commonly known as bitter melon & Momordica dioica commonly known as bitter melon both are very commonly available plants of Andra-Pradesh both fruits are proved to have antidiabetic activity. Ethanolic & Aqueous extracts of both Momordica fruits were prepared by Maceration, Percolation & Soxhlation & subjected to phytochemical screening & tested for anti-diabetic activity in alloxan induced diabetic rats.

   • Selon Yadav U (2005)

     Extrait The present study was undertaken to investigate the effects of treatment of Momordica charantia fruit extract & sodium orthovanadate, separately and in combination, on serum and tissue lipid profile & on the activities of lipogenic enzymes in alloxan induced diabetic rats. Momordica charantia commonly called bitter gourd, is a medicinal plant used in the Ayurvedic system of medicine for treating various diseases including diabetes mellitus.

   • Selon Yakaiah V (2013)

     Extrait to investigate the anti-diabetic effect of the bitter melon on Alloxan induced diabetes in experimental animals (rabbits. Materials & Methods: the alcohol extract of whole fruit was tested for its efficacy in Alloxan (150mg/kg induced diabetic rabbit.

   • Selon BISWAS AR (1991)

     Extrait In the Ayurvedic system of medicine, the fruits of this plant have been traditionally used for the treatment of diabetes mellitus and hepatic disorders & for pain relief in gout & rheumatism (Satapathy et al., 19871.In the present study, an attempt has been made to evaluate the analgesic activity of this plant in animals. charantia (authenticated by the Department of Botany of our Institute), collected during the month of December, were shade dried at room temperature for four weeks before the seeds were separated out.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.