Morus nigra (Murier) : vertus médicinales en extraction alcoolique

Morus nigra (Murier, Mulberry tree) — famille Moracées.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 37 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Extrait (2013) — extrait : The results suggest that BMFE can be used as a safe nutraceutical agent to ameliorate hyperglycemia associated with type II diabetes & it might also be useful in preventing secondary diabetic complications. To the best of our knowledge, this is the first study to report in vivo treatment of diabetic rats with ethanolic extract of M.

   • Selon Vukmirovic S (2023)

     Extrait The framework of this study was a comprehensive investigation of Morus nigra extracts, with the aim to establish the correlation between chemical composition & antioxidant/ hepatoprotective activity of a series of MN extracts obtained from aerial parts of the plant MN leaf (MLEE), bark (MBEE), juice (MJ) & fresh fruit (MFEE) extracts were obtained using the conventional Soxhlet extraction, while the supercritical CO2 extraction procedure was employed for preparation of the seed oil (MSO). In Haan strain NMRI mice with streptozotocin-induced oxidative stress, in vivo antioxidant activity and liver tissue integrity were examined.

   • Selon Da Silva A JRG (2012)

     Extrait Da Silva A JRG et al, Medicinal plants & natural compounds from the genus Morus (Moraceae) with Hypoglycemic activity: A review, Intechopen 2012.

   • Selon ENRUYGUR N (2019)

     Extrait Morus alba & Morus nigra leaves which have been widely used as herbal teas in Anatolian region of Turkey, were extracted twice by 50 mM HCI solution, derivatized with 9-fluorenylmethyl chloroformate & analyzed by reversed phase HPLC equipped with a fluorescence detector. Hypothesis/ purpose: This study was performed to determine the main antidiabetic active compounds 1-deoxyno-jirimycin by HPLC method & evaluate the in-vitro antioxidant & antidiabetic activity of ethanol extracts prepared from MA & MN leaves.

2. 2

   Diabete mellitus de type II

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Extrait (2013) — extrait : The results suggest that BMFE can be used as a safe nutraceutical agent to ameliorate hyperglycemia associated with type II diabetes & it might also be useful in preventing secondary diabetic complications. To the best of our knowledge, this is the first study to report in vivo treatment of diabetic rats with ethanolic extract of M.

   • Selon Vukmirovic S (2023)

     Extrait The framework of this study was a comprehensive investigation of Morus nigra extracts, with the aim to establish the correlation between chemical composition & antioxidant/ hepatoprotective activity of a series of MN extracts obtained from aerial parts of the plant MN leaf (MLEE), bark (MBEE), juice (MJ) & fresh fruit (MFEE) extracts were obtained using the conventional Soxhlet extraction, while the supercritical CO2 extraction procedure was employed for preparation of the seed oil (MSO). In Haan strain NMRI mice with streptozotocin-induced oxidative stress, in vivo antioxidant activity and liver tissue integrity were examined.

   • Selon Da Silva A JRG (2012)

     Extrait Da Silva A JRG et al, Medicinal plants & natural compounds from the genus Morus (Moraceae) with Hypoglycemic activity: A review, Intechopen 2012.

   • Selon ENRUYGUR N (2019)

     Extrait Morus alba & Morus nigra leaves which have been widely used as herbal teas in Anatolian region of Turkey, were extracted twice by 50 mM HCI solution, derivatized with 9-fluorenylmethyl chloroformate & analyzed by reversed phase HPLC equipped with a fluorescence detector. Hypothesis/ purpose: This study was performed to determine the main antidiabetic active compounds 1-deoxyno-jirimycin by HPLC method & evaluate the in-vitro antioxidant & antidiabetic activity of ethanol extracts prepared from MA & MN leaves.

3. 3

   Cancer : traitement adjuvant de l’hépatocarcinome

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Extrait (2013) — extrait : Furthermore, administration of BMFE at two different doses significantly improved liver and kidney function in diabetic rats.

   • Selon Auteur (2015)

     Extrait The possible hepatoprotective effect of the administration of Mulberry ethanolic extract (MUL) leaves against Hepatotoxic effect of the antirheumatic drug, methotrexate (MTX) was evaluated in this study both vivo (using animal models) and in vitro (human hepatoma HepG2 cells).METHODS: In the in-vivo study, 20 male albino rats were equally assigned into four groups; control group received distilled water orally; MUL treated-group received 500 mg/kg/day of MUL extract; MTX treated-group was injected with a single dose of 20 mg/kg MTX intraperitoneally on the 4th day; MUL-MTX treated-group received the previously mentioned doses of MUL & MTX (both control & MUL treated groups were administered a single dose of a physiological saline i.p.). At the end of the experimental period (14 days) activities of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) & lactate dehydrogenase (LDH) as well as total serum protein (TP) & albumin (ALB) levels were evaluated to assess liver function.

   • Selon Gonzalez-Condori EG (2021)

     Extrait Objective: Evaluate the hepatoprotective effect of Morus nigra hydroalcoholic extract on acetaminophen-induced liver damage in rats. Methods: Twenty rats (Rattus novergicus albinus) were distributed into four groups: control, acetaminophen (250 mg/kg) as hepatotoxicity control group, acetaminophen + silymarin (100 mg/kg) and acetaminophen + Morus nigra L.

   • Selon Vukmirovic S (2023)

     Extrait The framework of this study was a comprehensive investigation of Morus nigra extracts, with the aim to establish the correlation between chemical composition & antioxidant/ hepatoprotective activity of a series of MN extracts obtained from aerial parts of the plant MN leaf (MLEE), bark (MBEE), juice (MJ) & fresh fruit (MFEE) extracts were obtained using the conventional Soxhlet extraction, while the supercritical CO2 extraction procedure was employed for preparation of the seed oil (MSO). In Haan strain NMRI mice with streptozotocin-induced oxidative stress, in vivo antioxidant activity and liver tissue integrity were examined.

   • Selon Mallhi TH (2014)

     Extrait Mallhi TH et al, Hepatoprotective activity of aqueous methanolic extract of Morus nigra against paracetamol-induced hepatotoxicity in mice.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.