Nerium oleander (Lôyé-wôz) : vertus médicinales en extraction alcoolique

Nerium oleander (Lôyé-wôz, laurier rose, oleander) — famille Apocynacées.

Synonymes scientifiques : Nerium flavescens-Spin, N indicum-Mill, N japonicum-Gentil, Oleander indica (Mill.) Medik, Oleander Indica-(Mill)-Medik, O. vulgaris Medik..

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 15 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 121 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type ii

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sikarwar MS (2009)

     Extrait This research aims to investigate the antidiabetic activity of Nerium indicum leaf extract in alloxan induced diabetic albino rats. In alloxan induced model, blood glucose level of these extracts on the seventh day of study were NICE (113.33±6.662) & NIEE (169.33±9.735) in comparison of diabetic control (413.50 ±4.752) & petroleum ether extract (337.83±25.515).

   • Selon Ayaz M (2015)

     Extrait Protective and restorative effects of distillated Nerium oleander (NO) on the diabetes-induced electrophysiological & structural alterations were investigated. Distillated N oleander (NO) can be a highly potential therapeutic or preventive agent on the diabetes induced excitation-contraction coupling alterations Patent No: WO/2010/082906.

   • Selon Levent Bas A (2012)

     Extrait Type 2 diabetic Nerium-oleander- (NO-) administered groups received the NO distillate at a dose of 3.75, 37.5, & 375 μg/0.5 mL of distilled water (NO-0.1, NO-1, NO-10, resp.); positive control group had 0.6 mg glibenclamide/kg bw/d by gavage daily for 12 weeks. Diabetes was induced by intraperitoneal injection of streptozotocin (35 mg/kg bw) in all rats of 5 groups after being fed for 2 weeks high-fat diet.

   • Selon Ayaz M (2012)

     Extrait The current study aims to investigate the possible role of Nerium oleander (NeOL) distillate in the treatment of diabetic neuropathy. Induction of diabetes was done by the combination of single dose streptozotocin injection together with a high fat diet for four weeks.

   • Selon Basak Yanardag S (2015)

     Extrait The current study aims to investigate the possible role of Nerium oleander (NeOL) distillate in the treatment of diabetic neuropathy. Induction of diabetes was done by the combination of single dose streptozotocin injection together with a high fat diet for four weeks.

2. 2

   Infection bactérienne : Bacillus subtilis, Staphylococcus aureus , Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Erwich, E (2010)

     Extrait Escherichia coli, Pseudomonas aeruginosa & Staphylococcus aureus were used as test bacterial strains. The objective of this work is to investigate the main chemical composition and antibacterial activity of Nerium oleander flowers growing in Morocco.

   • Selon Fartyal M (2014)

     Extrait The present study was designed to evaluate the antibacterial activity of crude extracts of Nerium oleander Crude extracts from different parts (root, stem & leaf) of the plant were extracted using polar (Water & Methanol) & Non-polar (Petroleum ether) solvents & were screened for antibacterial activity by „Disc Diffusion Assay‟ against three Gram negative bacteria (Escherichia coli, Klebsiella pneumoniae & Agrobacterium tumifaciens) & two Gram positive bacteria (Staphylococcus aureus and Bacillus subtilis). Pet ether extract of root (IZ=24 mm, MIC=0.078 mg/ml, MBC=0.039 mg/ml, TA=141.02 ml/g) & stem (IZ=20 mm, MIC=0.156 mg/ml, MBC= 0.078 mg/ml, TA= 16.02 ml/g) showed the best antibacterial activity against B.

   • Selon Fartyal M (2014)

     Extrait Results of the present study reveal that extracts of NO have great antimicrobial potential against tested microorganisms, & may be exploited for future antimicrobial drugs. subtilis (IZ=14 mm, MIC=0.312mg/ml, MBC= 0.156mg/ml, TA=62.5ml/g), similarly Free flavonoid extract of root were best against B.

   • Selon Ma YM (2017)

     Extrait Among them, compound 2 revealed potent antibacterial activity against Staphylococcus aureus with MIC value of 15.6 μg/mL. Meanwhile, the antibacterial & antifungal activities of all compounds were tested, & the results showed that three compounds had strong antifungal activity.

   • Selon Saranya S (2017)

     Extrait In the present study, the antimicrobial & antioxidant properties of the flower extract of Nerium oleander were evaluated as a remedy for pathogenic diseases. The findings indicated that N oleander flowers have various phytopharmacological activities & thus it would be useful for the treatment of various diseases in future.

3. 3

   Peste de la tomate : Sclerotium rolfsii, Fusarium oxysporum

   Partie usitée : Parasiticide et vétérinaire.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Siddiqui L (2016)

     Extrait Nerium oleander was screened for antifungal activity against three economically important fungi Macrophomina phaseolina, Sclerotium rolfsii & Fusarium oxysporum, leaves stem & root extracts in aqueous, methanol, ethanol, choloroform & acetone were prepared & were evaluated for their in vitro antifungal ability. oxysporum trend has entirely changed, shoot induced the maximum effect as the diameter of the fungal colony was 0.37 in acetone; this trend was followed by chloroform & ethanol shoot extracts respectively.

   • Selon Fartyal M (2014)

     Extrait The present study was designed to evaluate the antibacterial activity of crude extracts of Nerium oleander Crude extracts from different parts (root, stem & leaf) of the plant were extracted using polar (Water & Methanol) & Non-polar (Petroleum ether) solvents & were screened for antibacterial activity by „Disc Diffusion Assay‟ against three Gram negative bacteria (Escherichia coli, Klebsiella pneumoniae & Agrobacterium tumifaciens) & two Gram positive bacteria (Staphylococcus aureus and Bacillus subtilis). Pet ether extract of root (IZ=24 mm, MIC=0.078 mg/ml, MBC=0.039 mg/ml, TA=141.02 ml/g) & stem (IZ=20 mm, MIC=0.156 mg/ml, MBC= 0.078 mg/ml, TA= 16.02 ml/g) showed the best antibacterial activity against B.

   • Selon Saranya S (2017)

     Extrait In the present study, the antimicrobial & antioxidant properties of the flower extract of Nerium oleander were evaluated as a remedy for pathogenic diseases. The findings indicated that N oleander flowers have various phytopharmacological activities & thus it would be useful for the treatment of various diseases in future.

   • Selon Erwich, E (2010)

     Extrait The objective of this work is to investigate the main chemical composition and antibacterial activity of Nerium oleander flowers growing in Morocco. To evaluate the antibacterial activities of these aromatic extracts; there in vitro antibacterial activities were determined by disk diffusion testing and minimum inhibitory concentration (MIC).

   • Selon Ma YM (2017)

     Extrait Meanwhile, the antibacterial & antifungal activities of all compounds were tested, & the results showed that three compounds had strong antifungal activity. Among them, compound 2 revealed potent antibacterial activity against Staphylococcus aureus with MIC value of 15.6 μg/mL.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.