Nigella sativa (Tjimen nwè) : vertus médicinales en extraction alcoolique

Nigella sativa (Tjimen nwè, Cumin noir, Black cumin) — famille Renonculacées.

Synonymes scientifiques : Nigella sativa-L, var sativa.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 337 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Vasoconstriction aortique chez le sujet diabétique

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Abbasnezhad A (2016)

     Extrait The present study investigated the effects of hydroalcoholic extract of Nigella sativa on contractile dilatation response of isolated aorta in streptozotocin (STZ)-induced diabetic rat. Conclusion: Chronic administration of NS seed extract has a significant hypoglycemic effect & improves aortic reactivity to vasoconstrictor & vasodilator agents in STZ-induced diabetic rats.

   • Selon Khan A (2011)

     Extrait The crude oil & thymoquinone (TQ) extracted from its seeds and oil are effective against many diseases like cancer, cardiovascular complications, diabetes, asthma, kidney disease etc. Nigella sativa has been used as traditional medicine for centuries.

   • Selon Hadj V (2021)

     Extrait Nigella sativa in controlling Type 2 diabetes, cardiovascular, & rheumatoid arthritis diseases: Molecular aspects, Jl Res Med Sci, 31:26:20.2021-Abtract: Oxidative stress is an important factor in the etiology of several chronic diseases that include cardiovascular disease (CVD), Type 2 diabetes (T2D), & rheumatoid arthritis (RA). One of the treatment options for chronic diseases is the use of traditional medicine & herbs, such as Nigella sativa.

   • Selon Shafiq H (2014)

     Extrait Nigella sativa is the miraculous plant having a lot of nutritional & medicinal benefits, & attracts large number of nutrition & pharmacological researchers. NS is rich source of different biologically active compounds & is found effective in controlling number of cardiovascular diseases & various cancers both in vivo & in vitro studies,.

   • Selon Dara-khan S (2015)

     Extrait In addition, positive effects of TQ in cardiovascular disorders, diabetes, reproductive disorders & respiratory ailments, as well as in the treatment of bone complications as well as fibrosis have been shown. Thymoquinone (TQ) is the most abundant constituent of the volatile oil of Nigella sativa seeds & most properties of NS are mainly attributed to TQ.

2. 2

   Pied diabétique, ulcère dermique

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mirazi N (2019)

     Extrait The aim of this study was to investigate the effect of hydroethanolic Nigella sativa L. extract on skin wound healing in diabetic male rats.

   • Selon Salahuddin N (2020)

     Extrait Nigella sativa (NS) has been reported to have a therapeutic effect towards skin wound healing via its anti-inflammatory, tissue growth stimulation, and antioxidative properties. This review examines all the available studies on the association of Nigella sativa (NS) and skin wound healing.

   • Selon Abbasnezhad A (2016)

     Extrait The present study investigated the effects of hydroalcoholic extract of Nigella sativa on contractile dilatation response of isolated aorta in streptozotocin (STZ)-induced diabetic rat. Conclusion: Chronic administration of NS seed extract has a significant hypoglycemic effect & improves aortic reactivity to vasoconstrictor & vasodilator agents in STZ-induced diabetic rats.

   • Selon Khan A (2011)

     Extrait Nigella sativa has been used as traditional medicine for centuries. The crude oil & thymoquinone (TQ) extracted from its seeds and oil are effective against many diseases like cancer, cardiovascular complications, diabetes, asthma, kidney disease etc.

   • Selon Tiwari O (2024)

     Extrait TQ is the main phytoconstituent present in NS that is used as an herbal compound, & it is widely used as an antihypertensive, liver tonic, diuretic, digestive, anti-diarrheal, appetite stimulant, analgesic, & antibacterial agent, & in skin disorders. Methods: Antidiabetic, anticancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, hepato-protective, renal protective, & antioxidant properties of TQ have been studied by various scientists.

3. 3

   Diabete mellitus de type II

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Khan A (2011)

     Extrait Nigella sativa has been used as traditional medicine for centuries. The crude oil & thymoquinone (TQ) extracted from its seeds and oil are effective against many diseases like cancer, cardiovascular complications, diabetes, asthma, kidney disease etc.

   • Selon Ali-Mohammadi S (2013)

     Extrait The present study investigated the effects of Nigella sativa hydroalcoholic extract on glucose concentrations in streptozotocin (STZ) diabetic rats. These results showed that hydroalcoholic extract of NS at low doses has hypoglycemic effect & ameliorative effect on regeneration of pancreatic islets & may be used as a therapeutic agent in the management of diabetes mellitus.

   • Selon Mirazi N (2019)

     Extrait The aim of this study was to investigate the effect of hydroethanolic Nigella sativa L. Methods This experimental study was conducted on 49 male Wistar rats weighing 220–250 g divided into 7 groups of 7 each: control (nondiabetic untreated), sham (nondiabetic Eucerin-treated), nondiabetic phenytoin (1%)-treated, diabetic untreated, & three diabetic groups treated independently with phenytoin 1%, hydroethanolic NS extracts 20% or 40%.

   • Selon Abbasnezhad A (2015)

     Extrait The aim of this study was to investigate the effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in STZ-induced diabetic rats' hippocampus. Materials & methods: Diabetes induced by 60 mg/kg STZ, i.p, & the rats were divided into five experimental groups (n=8-10 in each group) including control (received 0.5 ml normal saline), untreated STZ-diabetic (received 0.5 ml normal saline), & treated rats received NS extract (200 & 400 mg/kg) or metformin (300 mg/kg) by gavage for 42 days.

   • Selon Abbasnezhad A (2016)

     Extrait The present study investigated the effects of hydroalcoholic extract of Nigella sativa on contractile dilatation response of isolated aorta in streptozotocin (STZ)-induced diabetic rat. Conclusion: Chronic administration of NS seed extract has a significant hypoglycemic effect & improves aortic reactivity to vasoconstrictor & vasodilator agents in STZ-induced diabetic rats.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.