Olea europaea (Zolivié) : vertus médicinales en extraction alcoolique

Olea europaea (Zolivié, Olivier) — famille Oleacacées.

Synonymes scientifiques : Olea europaea subsp. Africana-(Mill)-P.S. Green, O europaea var. buxifolia-Sol, europaea subsp. Cerasiforme-G.K. & S, var picholine marocaine, var Corregiola & Frantoio.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 19 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 102 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Omer Musa Izzy Eldin (2015)

     Extrait The effect of 200,400 & 800 mg/kg of ethanolic extract of Olea europaea leaves was evaluated in both glucose-loaded Wistar albino rats & in glucose uptake by using isolated rats hemidiaphragms. Their effects were compared to control rats administered with the vehicle & to a standard group administered with the standard drug Glibenclamide.

   • Selon FARAH SH (2015)

     Extrait The effect of ethanolic extraction of olive leaves on alloxan – induced diabetic rabbits and lipid profile has been investigated. The maximum hypoglycemic activity (about 20% reduction in blood glucose level) was obtained from the treatment of diabetic rabbits with 600mg/ kg.

   • Selon Eidi A (2009)

     Extrait The antidiabetic effect of an alcohol extract of olive (Olea europaea L.) leaves was investigated in normal & streptozotocin-induced diabetic rats. The oral administration of the olive leaves extract (0.1, 0.25 & 0.5 g/kg body wt) for 14 days significantly decreased the serum glucose, total cholesterol, triglycerides, urea, uric acid, creatinine, aspartate amino transferase (AST) & alanine amino transferase (ALT) while it increased the serum insulin in diabetic rats but not in normal rats (p < 0.05).

   • Selon Sato H (2007)

     Extrait Olive tree (Olea europaea) leaves are well known for their effect on metabolism in particular as a traditional anti-diabetic & anti-hypertensive herbal drug. Our data suggest that both oleuropein & oleanolic acid are involved in the anti-diabetic effect of olive leaves & further emphasize the potential role of TGR5 agonists to improve metabolic disorders.

   • Selon Zeytünlüoğlu A (2015)

     Extrait Dipeptidyl peptidase IV (DPP IV) is a serine amino (exo) peptidase which regulates various processes most notably plasma glucose homeostasis by cleaving incretin peptide hormones as glucagon-like peptide-1 (GLP-1) & glucose-dependent insulin releasing polypeptide (GIP). The present study was designed to investigate the DPP IV inhibitory effects of sixteen plants having antidiabetic property in aqueous extracts in correlation with their protein content.

2. 2

   Infection bacterienne : E. coli, Pasteurella multocida, Bacillus cereus, Salmonella Enteritidis & Mycoplasma gallisepticum

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon HEMEG HA (2020)

     Extrait This study evaluates the antimicrobial effects of ethanolic extract of five herbal plants; Guava (Psidium guajava), Sage (Salvia officinalis), Rhamnus (Ziziphus-spina Christi), Mulberry (Morus alba L.), & Olive (Olea europaea L) leaves against several microbial population representing Gram positive, Gram negative & Mollicutes; S. cereus, Salmonella Enteritidis & Mycoplasma.

   • Selon Hassan A (2020)

     Extrait coli, Pasteurella multocida, Bacillus cereus, Salmonella Enteritidis & Mycoplasma gallisepticum using standard agar disc diffusion technique & minimal inhibitory concentration (MIC). This study evaluates the antimicrobial effects of ethanolic extract of five herbal plants; Guava (Psidium guajava), Sage (Salvia officinalis), Rhamnus (Ziziphus spina Christi), Mulberry (Morus alba L.), & Olive (Olea europaea L) leaves against several microbial population representing Gram positive, Gram negative & Mollicutes; S.

   • Selon Pereira A.P (2007)

     Extrait We report the determination of phenolic compounds in olive leaves by reversed-phase HPLC/DAD, & the evaluation of their in vitro activity against several microorganisms that may be causal agents of human intestinal & respiratory tract infections, namely gram positive (Bacillus cereus, B. At low concentrations olive leaves extracts showed an unusual combined antibacterial & antifungal action, which suggest their great potential as nutraceuticals, particularly as a source of phenolic compounds.

   • Selon ZAFAR A (2010)

     Extrait The synergy of these antibiotics with the ethanolic extracts of stem & leaf of Olea Europaea was also investigated. The combination of stem & leaf extract with Penicillin (23.O mm & 22.5 mm respectively), could not produce the same inhibitory effect as that of Chloramphenicol & O europaea stem & leaf extracts.

   • Selon BAYCIN D (2007)

     Extrait Silk fibroin also gained antimicrobial activity against Staphylococcus aureus & Klebsiella pneumoniae after adsorption of olive leaf antioxidants.

3. 3

   Cancer : traitement adjuvant du carcinome pancréatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Goldsmith CD (2015)

     Extrait Therefore, water, 50% ethanol & 50% methanol extracts of Corregiola & Frantoio variety O-europaea leaves were investigated for their total phenolic compounds, total flavonoids & Oleuropein content, antioxidant capacity & anti-proliferative activity against MiaPaCa-2 pancreatic cancer cells. The extracts only had slight differences in their phytochemical properties, & at 100 & 200 μg/mL, all decreased the viability of the pancreatic cancer cells relative to controls.

   • Selon Giner E (2016)

     Extrait The main phenolic secoiridoid oleuropein and active constituent from olive tree (Olea europaea, Oleaceae), has demonstrated anti-inflammatory properties in intestinal inflammation & anti-tumoral effects in different cancer cells. In this study, we evaluated the chemoprevention of oleuropein in a model of azoxymethane (AOM)/Dextran sulfate sodium (DSS)-induced colorectal cancer (CRC) in C57BL/6 mice & the modulatory effect on the Th17 response in DSS acute colitis.

   • Selon Abaza L (2007)

     Extrait The protective effects of olive (Olea europaea L.) leaves were investigated by incubating human promyelocytic leukemia HL-60 cells with olive leaf extracts (OLEs) from seven principal Tunisian olive varieties, namely, Chemchali, Chemlali, Chétoui, Gerboui, Sayali, Zalmati & Zarrazi. Cancer protection associated with the consumption of olive products is well established, but not for leukemia.

   • Selon Fares (2011)

     Extrait In this study, the anti-proliferative activity of plant extracts from olive (Olea europaea L.) leaves was tested on human leukemic cell line (Jurkat). It is becoming increasingly evident that certain phytochemicals possess cancer chemopreventive properties.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.