Origanum vulgare (Origan) : vertus médicinales en extraction alcoolique

Origanum vulgare (Origan, Oregano) — famille Lamiacées.

Synonymes scientifiques : Majorana neglecta-(V)-W, Origanum hirtum L, O Illyricum-S, O megastachyum-L, O neglectum-V, O smymaeum-Sm, O vulgare var megastachyum-(L)-WDJ Koch.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 55 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Infection bacterienne: Acinobacter baumannii, Bacillus subtilis, Bordetella bronchiseptica, Pseudomonas aeruginosa, Staphylococcus aureus

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Liçina BZ (2013)

     Extrait The strongest antibacterial activity, determined by microdilution method, was detected on G+ bacteria such as Bacillus species & Staphylococcus aureus, obtaining minimal inhibitory concentration (MIC) 0.16 mg/ml while antifungal activity was moderate with MICs between 2.5 & 20 mg/mL. The present work was undertaken to determine the total phenol, flavonoid & tannin content in five extracts of Origanum vulgare growing wild in southwest Serbia as well as to evaluate antioxidant & antimicrobial activity towards 29 strains of human pathogenic & food spoilage bacteria & fungi.

   • Selon Puskarova A (2017)

     Extrait The in vitro antibacterial activity of six EOs against bacterial strains from both clinical and environmental origins (both Gram-positive & Gram-negative bacteria) was assayed using the disc diffusion method by measuring inhibition zone diameters (Fig. The differences in the measured inhibition halos of OR (p = 0.000457), TY (p = 0.000457) & Lavandula angustifolia (LA; p = 0.0117) on Staphylococcus aureus were statistically different from the control.

   • Selon Coccimiglio J (2016)

     Extrait This study was conducted to identify the major constituents of the ethanolic Origanum vulgare extract & examine the cytotoxic, antioxidant, & antibacterial properties of the extract but more importantly the contribution of its specific major constituent(s) or their combination to the overall extract biological activity. The extract also exhibited antimicrobial properties against Gram-positive & Gram-negative bacterial strains including clinical isolates.

   • Selon Khan M (2018)

     Extrait The essential oil & aqueous distillate composition of Origanum vulgare L. The data suggest that carvacrol, a major component of both oils, possesses the highest antibacterial activity of all the constituents and is the main component responsible for the antibacterial activity of Saudi O.

   • Selon Orhan I.E (2012)

     Extrait The essential oils obtained from Anethum graveolens, Foeniculum vulgare collected at fully-mature & flowering stages, Mentha piperita, Mentha spicata, Lavandula officinalis, Ocimum basilicum (green- & purpleleaf varieties), Origanum onites, O. Most of the tested oils & compounds exhibited good antibacterial & antifungal effects.

2. 2

   Cancer : traitement adjuvant de l’adénocarcinome colorectal & pulmonaire épithélial

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Yıldırım Q (2015)

     Extrait Other a study the cytotoxicity effect of petroleum ether, ethyl acetate, ethanol, & water of aerials parts of Origanum compactum were investigated on breast carcinoma cell (MCF-7). Sivas & Tomsuk determined cytotoxic & apoptotic effects of essential oil Origanum onites & its phenolic constituent carvacrol on human hepatocellular carcinoma cells (HepG2).

   • Selon Mashhadi F (2021)

     Extrait Results: We found that ethanolic extracts at a concentration of 1 mg/mL significantly increased lymphocyte proliferation (47% by Origanum vulgare & 95% by Origanum majorana compared to the control group). Mashhadi F et al, Immunomodulatory Effects of Origanum vulgare L.

   • Selon Grbović F (2013)

     Extrait In the present investigation, we examined the cytotoxic effect of methanolic extract from Origanum vulgare on HCT-116 & MDA-MB-231 cell line in vitro. Based on the results it is determined that OV is a significant source of biologically active substances that have cytotoxic & antiproliferative activity in vitro.

   • Selon Chuang LT (2018)

     Extrait In this study, we examined the suppressive effect of ethanolic Origanum vulgare extract on live P. acnes & human THP-1 monocytes, EOE reduced the production of interleukin (IL)-8, IL-1_ & tumor necrosis factor (TNF)-_ up to 40%, 37%, & 18%, respectively, as well as the expression of these three proinflammatory mediators at the transcriptional level.

   • Selon Koldas S (2015)

     Extrait vulgare & Origanum acutidens: rosmarinic acid (in highest abundance), chicoric acid, caffeic acid, p-coumaric acid, gallic acid, quercetin, apigenin-7-glucoside, kaempferol, naringenin & 4-hydroxybenzaldehyde. A detailed phytochemical analysis of Origanum vulgare L.

3. 3

   État inflammatoire : arthrose, arthrite, rhumatisme, oedeme

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon De Santis F (2019)

     Extrait Altogether, these results show that HyE-Ov promotes anti-mycobacterial innate immunity & limits inflammatory response in vitro & suggest that this plant extract may be exploitable as phytocomplex or nutraceutical for novel host-directed therapeutic approaches. Results showed that the capability to activate anti-microbial & anti-inflammatory response is shared by different fractions, suggesting that diverse bioactive molecules are present within the hydroalcoholic extract.

   • Selon Mazzarello V (2020)

     Extrait & Origanum vulgare) & tretinoin (MOTC) to evaluate its anti-acne effectiveness and action on the microclimate of the skin. Conclusion: MOTC has shown, compared to Acnatac, to have anti-acne efficacy & to possess an anti-inflammatory activity, due to essential oils, able to reduce in vivo erythematous lesions & those induced by retinoids,.

   • Selon Chuang LT (2018)

     Extrait In this study, we examined the suppressive effect of ethanolic Origanum vulgare extract on live P. acnes-induced inflammatory responses could be due, in part, to the anti-inflammatory.

   • Selon Lombrea A (2020)

     Extrait The antibacterial, antifungal, antiparasitic, antioxidant, anti-inflammatory, antitumor, skin disorders beneficial effects, next to antihyperglycemic & anti-Alzheimer activities were reported & confirmed in multiple studies. The ethnopharmacological uses of Origanum vulgare L.

   • Selon Yıldırım Q (2015)

     Extrait In a work; the anti-proliferative properties of Origanum acutidens (OA) was investigated on breast cancer cell lines MCF-7, MDAMB- 468 & MDA-MB-231. Dhaheri & colleagues studied the anti-metastatic & anti-tumor effect of Origanum majorana.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.