Passiflora foetida (Maribouya) : vertus médicinales en extraction alcoolique

Passiflora foetida (Maribouya, Pôk-môl, Ponm-dilyenn-Kolan, Poc mou, Pomme-de-liane, collante) — famille Passifloracées.

Synonymes scientifiques : Dysosmia foetida-(L.)-M. Roemer, Granadilla foetida-(L.)-Gaertner, Passiflora hispida-Cand ex Triana & Planch, Tripsilina foetida-(L.)-Rafinesque..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 18 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 74 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glipizide-like, Metformine-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Joseph P (2014)

     Extrait Investigation of the total phenol content, total flavanoid content, in vitro lipid peroxidation & radical scavenging activities from Passiflora foetida, Extraction from various solvents were used for the estimations. That the highest free radical scavenging activity was found in ethanolic extract of leaf of PF, Consumption of PF will reduce the free radical formation & afford protection against reactive oxygen species produced during diabetes which may be due to the presence of phenol & flavanoid.

   • Selon Asir PJ (2014)

     Extrait Aqueous & ethanolic extracts of Passiflora foetida 200 mg/kg (leaf, unripe (UR) peel, full ripens (FR) peel, seed & root) was administered orally for 14 days. All the animals were sacrificed after 14 days treatment & its effect on blood glucose, Glucose tolerance test (GTT), hepatic marker enzymes such as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), serum marker like urea, creatinine & protein in alloxan induced diabetic rats were examined.

   • Selon Birudu RB (2017)

     Extrait The objective of this study was to evaluate the antidiabetic activity of Passiflora foetida in a model of dextrose -induced experimental diabetes in rats. The effect of ethanol extract of P foetida leaf extract on blood glucose, plasma insulin, creatinine, glycosylated haemoglobin, serum protein, serum enzymes (serum glutamate pyruvate transaminases) serum glutamate oxaloacetate transaminases & alkaline phosphatase) were measured in the diabetic rats.

   • Selon Birudu RB (2015)

     Extrait In our study we used Passiflora foetida aerial parts against antidiabetic activity in rats. The carbohydrate metabolic enzymes were studied & there were elevation levels of carbohydrate metabolizing enzymes when treated with extract when compared with doxorubicin induced diabetic rats.

   • Selon Birudu RB (2014)

     Extrait In present study ethanol extracts of Passiflora foetida leaves were evaluated for antidyslipidemia activity in dextrose induced diabetic rats. foetida were administered at the doses of 100 mg/kg body weight, 250 mg/kg body weight and 500 mg/kg body weight to the dextrose induced diabetic rats.

2. 2

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ramaswamy A (2009)

     Extrait Hepatoprotective activity of ethanolic extract of fruits of Passiflora foetida was studied against CCl4 induced hepatic injury in albino rats. Pretreatment of ethanolic extract (EPF 200 mg/kg/day, p.o.) significantly (p<0.001) reduced the biochemical markers of hepatic injury like serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), alkaline phosphatase (ALP), total bilirubin & gamma glutamate transpeptidase (GGTP). (2018) — extrait : The aim of this work was to evaluate the main nutrients and their antioxidant properties of a Chinese wild edible fruit, Passiflora foetida, collected from the ecoregion of Hainan province, China.

   • Selon Michel BG (2022)

     Extrait In this study, we investigate the possible hepatoprotective effect of the aqueous extract of Passiflora foetida (AEPF) using paracetamol-induced liver damage albino rats as animal model. Results showed that in group II, PCM increased significantly the activity of liver enzymes (ALT, AST, & PAL), the serum level of total & direct bilirubin and decreased significantly the serum level of total cholesterol, triglyceride & total protein in rats.

   • Selon Bala-Subramaniam A (2010)

     Extrait Bala-Subramaniam A et al, Anticarcinogenic effect of Passiflora foetida Linn root on the development of liver cancer induced by DEN in rats.

   • Selon HAN X (2023)

     Extrait This study aimed to explore the anti-inflammatory & d gut microbiota modulation potentials of flavonoid-rich fraction (PFF) extracted from Passiflora foetida fruits.

3. 3

   Cancer : traitement adjuvant du carcinome mammaire

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Moongkarndi P (2004)

     Extrait niruri] whole plant, Passiflora foetida aerial part, Ardisia elliptica fruit, Morinda citrifolia fruit, Aegle marmelos fruit, Heliotropium indicum whole plant, Stephania venosa [Stephania rotunda] bulb a& Thunbergia laurifolia leaf) were tested for antiproliferative activity against SKBR3 human breast adenocarcinoma cell line using MTT assay. However, all the plant extracts showed activity in potential range for further investigation on cancer cells, showed activity in potential range for further investigation on cancer cells.

   • Selon Bala-Subramaniam A (2010)

     Extrait Bala-Subramaniam A et al, Anticarcinogenic effect of Passiflora foetida Linn root on the development of liver cancer induced by DEN in rats.

   • Selon SISIN NNT (2017)

     Extrait This study was conducted to determine the antiproliferative & antioxidant activities of Passiflora foetida leaves methanolic extract (PFME) against MCF-7, MDA- MB-231, HeLa & Hep G2 cancer cell lines, as well as to determine the antiproliferative activity of the major fractions against HeLa cells, & evaluate the compounds present in the PFME & fractions. Antiproliferative activity towards MCF-7 (HTB22TM) & MDA-MB-231 (HTB-26TM) breast cancer cell lines, Hep G2 (HB8065TM) liver cancer cell line, HeLa (CCL-2TM) cervical cancer cell line & L929 (CCL-1TM) normal cell line were observed & compared to Tamoxifen as a positive control.

   • Selon HAN X (2023)

     Extrait This study aimed to explore the anti-inflammatory & d gut microbiota modulation potentials of flavonoid-rich fraction (PFF) extracted from Passiflora foetida fruits. The results showed that PFF markedly reduced the production of nitric oxide (NO), tumor necrosis factor α (TNF-α), & interleukin 6 (IL-6) in LPS-stimulated RAW 264.7 cells.

   • Selon Sripathi KS (2023)

     Extrait Passiflora foetida, commonly known as stinking passion flower has been used as traditional medicine in treating diseases such as throat infection, giddiness, liver disorder, diarrhea, tumor, nervous disorder, anxiety; sleep disorders, skin infections, hysteria & asthma. In addition, PF has been reported to have potential antioxidant, anti-inflammatory, antiepileptic, anti hyperglycemic, cardio protective, anti-diarrheal, & anti- cancer properties.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.