Persea americana (Zaboka) : vertus médicinales en extraction alcoolique

Persea americana (Zaboka, Avocat, Lawyer) — famille Lauracées.

Synonymes scientifiques : Laurus persea-L, Persea gratissima var. oblonga-Meisn, P paucitriplinervia-Lindell, P steyermarkii-C.K.A.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 22 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 72 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome hépatique

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ochoa-Zarzosa A (2021)

     Extrait Avocado (Persea americana Mill.) is a tree native from central & eastern México that belongs to the Lauraceae family. Besides, this fruit possesses a high content of carotenoids & phenolic compounds with possible antifungal, anti-cancer & antioxidant activities.

   • Selon Mvondo MA (2021)

     Extrait The ethanol extract of Persea americana seeds was found exhibiting antiproliferative properties in vitro. In conclusion, the ethanol extract of PA seeds could be a complementary treatment to prevent tamoxifen-induced endometrial hyperplasia during the treatment of ER+ breast cancer,.

   • Selon D’Ambrosio SM (2011)

     Extrait Persea americana fruits are consumed as part of the human diet & extracts have shown growth inhibitory effects in various types of human cancer cells, although the effectiveness of individual components & their underlying mechanism are poorly understood. The present data suggest that the potential anticancer activity of avocado fruits is due to a combination of specific aliphatic acetogenins that target two key components of the EGFR/RAS/RAF/MEK/ERK1/2 cancer pathway.

   • Selon Hamouda AF (2016)

     Extrait The effect of AVOE (avocado), GE (Ginger) & CE (Cabbage) extracts separately on liver NO (nitric oxide), MDA (malondialdehyde), as well as serum AST (aspartate aminotransferase), ALT (alanine aminotransferase), total bilirubin, TC (total cholesterol), T.G (triglyceride), HDL cholesterol (high-density lipoprotein), LDL cholesterol (low-density lipoprotein), TSH (thyroid-stimulating hormone), T3 (Triiodothyronine), T4 (Thyroxine) in rats treated & untreated with CCl4 (carbon tetrachloride) was studied. Avocado, Cabbage, & Ginger are a part of a regular human diet & have antioxidant, & antitumor effects.

   • Selon Padmanabhan M (2013)

     Extrait The aim of the present study was to evaluate the hypolipidemic & antiatherogenic effect of Persea americana (Avocado) fruit extract on the level of tissue and blood lipids & adiponectin in the adipocytes of rats subjected to experimental hyperlipidemia and atherogenesis. americana was found to reduce the risk of hyperlipidemia probably by elevating the level of adiponectin & also by reducing the level of LDL-C.

2. 2

   Diabète mellitus type II

   Partie usitée : Semence. Profil pharmacologique documenté : Acarbose-like. Association synergique mentionnée : Zea mays-stigmate.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Okon AJ (2018)

     Extrait The effect of ethanolic extracts of Persea americana seed & Zea mays silk on blood glucose levels, body & organ weights of alloxan- induced hyperglycemic Wistar rats was investigated using standard analytical techniques. At the end of the experiment, the groups administered 400 mg/kg body weight Zea mays silk single extract & 400 mg/kg body weight combined extract of P americana seed Z mays silk showed significant (P< 0.05) decrease in fasting blood glucose when compared with the diabetic control.

   • Selon OJO AO (2019)

     Extrait An aqueous extract of Persea americana seeds (AEPAS) was explored in this study as a possible therapeutic agent in rats with diabetes mellitus. The diabetic control group exhibited pancreatic dysfunction as evidenced by a reduction in serum insulin, HOMA-β, expressions of PI3K/AKT, Bcl-2, & PCNA combined with an elevation in HOMA-IR.

   • Selon Ozegbe-Evita J (2021)

     Extrait Ozegbe-Evita J et al, Comparative effects of Carica Papaya, Avocado Pear & Ginger Extracts on the Histological Structure of the Pancreas of Streptozotocin-induced Diabetic Rats, Research-Gate, 2021-Abstractt: he increasing global prevalence of diabetes mellitus requires a holistic approach for its management. This study was carried out to compare the effects of Carica papaya leaves, Persea americana & Zingiber officinale on the histological structure of the pancreas of Streptozotocin (STZ)-induced diabetic Wistar rats.

   • Selon Agunloye MO (2025)

     Extrait Methods: A comprehensive review of relevant published literature was conducted using keywords such as ("avocado plant" or "Persea americana") & ("diabetes"). This review explores the therapeutic potential of Persea americana Mill plant (avocado) in diabetes management & its potential targets.

   • Selon Elya B (2015)

     Extrait These extracts are Camélia sinensis (white, green, fermented), Pometia pinnata, Syzygium polyanthum, Artocarpus heterophyllus, Lagerstroemia speciosa & Persea Americana.

3. 3

   Arthralgie, arthrite, arthrose, rhumatisme

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Adeyemi OO (2002)

     Extrait The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid & an elevation of pain threshold in the hot plate test in mice. The results obtained indicate that the extract possesses analgesic & anti-inflammatory effects.

   • Selon Ovalle-Marin A (2020)

     Extrait Furthermore, we report that hydroalcoholic leaves extract presented greater in vitro anti-inflammatory effect, especially the leave hydroalcoholic regarding NO release (p<0.001, against LPS treatment), aqueous & hydroalcoholics regarding TNF- release (p<0.05), & only the hydroalcoholic in the TNF- gene expression (p<0.01). In conclusion, the PA hydroalcoholic extracts, & especially from leaves, present in vitro anti-inflammatory features that might be considered for human health improvement applications.

   • Selon De Oliveira A.P (2013)

     Extrait Anti-inflammatory activity, increase in density of collagen, & tensile strength were observed in SSFAO 50% or PA oil groups, when compared to control groups. When used in natura or in pharmaceutical formulations for topical use, PA oil can promote increased collagen synthesis & decreased numbers of inflammatory cells during the wound-healing process & may thus be considered a new option for treating skin wounds,.

   • Selon HONG JY (2019)

     Extrait Taken together, our data indicate that ethanol extract of PA may be used as a promising therapeutic against inflammatory bowel diseases by suppressing the NF-κB & STAT3 signaling pathway,. In this study, we investigated anti-colitic effects of ethanol extract of PA (EEP) in dextran sulfate sodium (DSS)-induced colitic mice & the involved molecular mechanisms.

   • Selon Agunloye MO (2025)

     Extrait Methods: A comprehensive review of relevant published literature was conducted using keywords such as ("avocado plant" or "Persea americana") & ("diabetes"). This review explores the therapeutic potential of Persea americana Mill plant (avocado) in diabetes management & its potential targets.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.