Phaseolus vulgaris (Pwa-tann’) : vertus médicinales en extraction alcoolique

Phaseolus vulgaris (Pwa-tann’, Pwa wouj, Pois tendre, Pois rouge, Tender peas, Red peas) — famille Fabacées.

Synonymes scientifiques : Phaseolus esculentus-Salisb, P marus-L, P vulgaris-Bur.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 9 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 110 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome colorectal, hépatique, mammaire hormone-dependent & prostatique

   Partie usitée : Pelure du fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Guajardo-Flores D (2013)

     Extrait This research evaluated the effect of germination of Phaseolus vulgaris on the antioxidant capacity & antiproliferative activity against cancer cell lines of saponins & flavonoids extracted from seed coats, cotyledons & sprouts. Genistein was related with the activity against mammary cancer cells but flavonols & group B saponins were more related with hepatic & colon cancers.

   • Selon Henningson A (2001)

     Extrait Henningson A et al, Content of short-Chain fatty acids in the hindgut of rats Fed processed Bean (Phaseolus vulgaris) flours varying in distribution & content of indigestible carbohydrates, British J of Nutr, 2001; 86: 379-89.

   • Selon Finetti F (2020)

     Extrait Fagiola di Venâncio water extract is rich in proteins, sugars & polyphenols & displays antioxidant, anti-inflammatory & antiproliferative activities in in vitro assays on colon cancer cellular models. Phaseolus vulgaris L.

   • Selon Bernardi C (2023)

     Extrait Phaseolus vulgaris L. Using HT29 & HCT116 colon cancer cell lines, we showed that the extract obtained after gastrointestinal digestion of cooked beans (the bioaccessible fraction, BF) induces cell death through the induction of the autophagic process.

   • Selon Donoso-Quezada J (2020)

     Extrait Here we loaded saponins & flavonoids obtained from a black bean extract (Phaseolus vulgaris L.) with antiproliferative activity into exosomes extracted from different cell lines to induce an enhanced response in vitro.

2. 2

   Diabetes mellitus de type II

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Anggraini DR (2018)

     Extrait Alloxan (120 mg/kg, intraperitoneally)- induced diabetic rats were divided into 5 groups (n=5), i.e., NC: Normal control, P1: Diabetic-control, P2, P3, & P4 (200 mg/kg, 400 mg/kg, & 600 mg/kg of EEPV, orally) for 28 days. Malondialdehyde (MDA) is an important marker of oxidative stress that have correlation with Type 2 diabetes mellitus (DM) progression.

   • Selon Sinaga APF (2017)

     Extrait Alloxan tetrahydro mice causes free radicals & higher reactive oxidative species (ROS) production, being able to lead to reduce insulin secretion from SDQFUHDWLF Ã FHOOV DQG receptor sensitivity in insulin-receptor cells resulting in hyperglycemia conditions.

   • Selon Kyznetsova YM (2015)

     Extrait The social significance of diabetes mellitus lies in the fact that in addition to significant prevalence, this disease is associated with many complications. besides its pronounced hypoglycemic action also has a positive influence on the liver & kidney function markers in STZ-treated diabetic rats.

   • Selon Venkateswaran S (2002)

     Extrait The antioxidant effect of an aqueous extract of Phaseolus vulgaris pods, an indigenous plant used in Ayurvedic medicine in India, was studied in rats with streptozotocin-induced diabetes. The extract also causes a significant increase in reduced glutathione, superoxide dismutase, catalase, glutathione peroxidase & glutathione-S-transferase in the liver & kidneys of rats with streptozotocin-induced diabetes.

   • Selon Almualgel MF (2017)

     Extrait The present investigation was carried out to evaluate the reduction potential of aqueous extract of casing of pods of Phaseolus vulgaris in blood glucose & lipids levels among hyperglycemic streptozotocin (STZ)-induced rats. Oral administration of 150mg/kg of aqueous oral administration of aqueous pod extract of PV to diabetic rats for 40 days resulted in a significant decrease in blood glucose (p<001), cholesterol (P<0.01) & triglycerides (P<0.01).

3. 3

   HTA, retention hydrique, oedeme

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Garcia-Mora P (2015)

     Extrait Aimed at a better exploitation of the functional properties of pinto bean hydrolysates, the effectiveness of two subtilisins (Alcalase & Savinase) for the simultaneous release of bioactive peptides & phenolics with antioxidant, angiotensin I converting enzyme (ACE) inhibitory & anti-inflammatory activities was investigated. The most active hydrolysates combined potent free radical scavenging (326–348 mmol TE/g), ACE inhibitory (IC50 = 0.22–0.26 mg/mL) & anti-inflammatory (28–16% inhibition) activities.

   • Selon Oomah BD (2010)

     Extrait Hulls obtained by mechanical abrasive dehulling from four bean cultivars were extracted with two solvents, aqueous (70%) acetone & water, & the extracts evaluated for antioxidant & anti-inflammatory activities in relation to their phenolic contents. Anti-inflammatory activity of bean hulls was dependent on their phenolic content & antioxidant activity that were significantly affected by cultivar & extracting solvent,.

   • Selon Finetti F (2020)

     Extrait Phaseolus vulgaris L. Fagiola di Venâncio water extract is rich in proteins, sugars & polyphenols & displays antioxidant, anti-inflammatory & antiproliferative activities in in vitro assays on colon cancer cellular models.

   • Selon López Barrios L (2016)

     Extrait The effect of germinating black bean seeds on the production of cotyledon protein hydrolysates (CPH) with antioxidant & antiinflammatory activities was analyzed in this research. Peptides derived from cell wall proteins produced during germination could be responsible of antiinflammatory activity.

   • Selon Ganesan K (2017)

     Extrait Common beans (Phaseolus vulgaris L.) are a greater source of polyphenolic compounds with numerous health promoting properties. Polyphenol-rich dry common beans have potential effects on human health, & possess anti-oxidant, anti-diabetic, anti-obesity, anti-inflammatory & anti-mutagenic & anti-carcinogenic properties.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.