Phyllanthus acidus (Sirèt-Kochon) : vertus médicinales en extraction alcoolique

Phyllanthus acidus (Sirèt-Kochon, Surette-à-cochon, Pig trap) — famille Euphorbiacées.

Synonymes scientifiques : AverAverhoa acida Linn, Cicca acida (L.) Merr., C acidissima Blanco, C disticha Linn, C nodiflora Lam., C racemosa Lour., Diasperus acidissimus (Blanco) Kuntze, Phyllanthus acidissimus (Blanco) Muell.-Arg., P cicca Müell.Arg., P cochinchinensis Müell.Arg., P longifolius Jacq., Tricariumm cochinchinense Lour..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 16 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 103 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabete mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon SHOWMIK A (2010)

     Extrait A study was carried out to assess the hepatoprotective & hypoglycemic activity of the leaf extracts of Phyllanthus acidus in Wister albino rats against the widely used drugs i.e., Silymarin for hepatoprotective activity & Glibenclamide for hypoglycaemic activity. It also revealed that the alcohol extract of PA leaf possesses hypoglycemic activity at a dose of 200mg/Kg which is as effective as Glibenclamide, a commonly used drug for hypoglycaemic activity.

   • Selon YANI S (2025)

     Extrait The Phyllanthus acidus (L.) Skeels has been used as traditional medicine. It has been proved to have hepatoprotective, anti-inflammatory, antidiabetic, & antioxidant properties.

   • Selon Chaimumaom N (2017)

     Extrait The hypoglycemic effects of PAE on normal rats & orally glucose-induced hyperglycemic rats were compared with distilled water & Glibenclamide. the present study aimed to investigate toxicity & oral glucose tolerance test (OGTT) of Phyllanthus acidus leaf extract (PAE) on Wistar rat.

   • Selon RANTI I (2023)

     Extrait The present work investigated the preventive & attenuating effects of ethanolic extracts of Phyllanthus acidus (PA) & Zingiber aromaticum (ZA) against metabolic disturbances in a high-fat high-fructose (HFHF) diet-induced obesity model. The HFHF diet significantly increased BMI, adiposity index, triglycerides, cholesterol, fasting glucse, insulin, Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), leptin, malondialdehyde (MDA) compared with the standard diet.

   • Selon CHIGURUPATI S (2020)

     Extrait PSE’s hypoglycaemic effect was demonstrated in normo- glycemic & streptozotocin-induced (STZ, 55 mg/kg, ip) diabetic rats. The present work examined the antioxidant & antidiabetic potentials of seed extract of Phyllanthus acidus (L.) Skeels.

2. 2

   Troubles hépatiques : cirrhose, stéatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Jain NK (2010)

     Extrait To investigate & compare the hepatoprotective effects of crude ethanolic & aqueous extracts of Phyllanthus acidus (L.) Skeels (P. Conclusions: The results of present study suggests that the aqueous extract of PA leaves has significant hepatoprotective activity on APAP & TAA induced hepatotoxicity, which might be associate with its high phenolic & flavonoid content & antioxidant properties.

   • Selon SHOWMIK A (2010)

     Extrait A study was carried out to assess the hepatoprotective & hypoglycemic activity of the leaf extracts of Phyllanthus acidus in Wister albino rats against the widely used drugs i.e., Silymarin for hepatoprotective activity & Glibenclamide for hypoglycaemic activity. Phyllanthus acidus leaves were collected from different localities of Agartala, Tripura, India.

   • Selon YANI S (2025)

     Extrait The Phyllanthus acidus (L.) Skeels has been used as traditional medicine. It has been proved to have hepatoprotective, anti-inflammatory, antidiabetic, & antioxidant properties.

   • Selon Hossen MJ (2015)

     Extrait Hossen MJ et al, AP-1-Targeted Inhibition of Macrophage Function & Lipopolysaccharide/D-Galactosamine-Induced Hepatitis by Phyllanthus acidus Methanolic Extract Am. Moreover, pre-treatment with Pa-ME exhibited strong hepatoprotective and curative effects in an LPS/D-Gal-induced mouse hepatitis model as evidenced by a decrease in elevated serum AST and ALT levels and the amelioration of histological damage.

   • Selon Tan SP (2020)

     Extrait Phyllanthus acidus (L.) Skeels is not only used for its edible fruits but also used to treat a wide spectrum of diseases such as inflammatory, rheumatism, bronchitis, asthma, respiratory disorder, hepatic diseases & diabetes in India, Asia, the Caribbean region, & Central & South America. acidus was collected from various electronic database (ACS, PubMed, Scopus, Web of Science, SciFinder, Science Direct, Google Scholar, Springer, Wiley, Taylor & Mendeley) & also from those published materials (Ph.D.

3. 3

   Diarrhée

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hossain S (2016)

     Extrait The study was to evaluate the CNS depressant, antidiarrheal & antipyretic activities of ethanolic leaf extract of Phyllanthus acidus L. In castor oil induced diarrheal model the plant extract reduced thetime of onset & severity of diarrhea with significant (P = 0.05) inhibition of 42.86% & 64.29% for 250 & 500 mg/kg b.w extracts respectively whereas the standard drug loperamide (5 mg/kg) showed 71.43% diarrheal inhibitory activity.

   • Selon Nisar MJ (2018)

     Extrait Phyllanthus species are being in constant used in traditional medications to cure an array of human diseases (constipation, inhalation related, arthritis, loss of appetite, injuries, conjunctivitis, diarrhoea, running nose, common cold, malaria, blennorrhagia, colic, diabetes mellitus, dysentery, indigestion, fever, gout, gonorrheal diseases of males & females, skin itching, jaundice, hepatic disorders, leucorrhea, vaginitis, menstrual irregularities, obesity, stomach pains, & tumors), confectionaries, food industry, & in some pesticides. Phyllanthus is one of the largest genera in the family Phyllanthaceae, comprising over 700 well known species cosmopolitan in distribution mainly in the tropics & subtropics.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.