Piper amalago (Malenmbé) : vertus médicinales en extraction alcoolique

Piper amalago (Malenmbé) — famille Pipéracées.

Synonymes scientifiques : Piper berlandieri-C DC., P. lundelii-Trel, P. vaccinium-Standl. & Steyerm..

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 6 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 39 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   HTA, rétention hydrique

   Partie usitée : Feuille. Profil pharmacologique documenté : Hydrochlorothiazide-lie.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2014)

     Extrait Therefore, this study aimed to evaluate the anti- inflammatory & analgesic effects of PA ethanolic extract (EEPA) & its isolated compound N-[7-(3′,4′-Methylenedioxyphenyl)-2(Z),4(Z)-hepta-dienoyl]pyrrolidine in experimental models of inflammation (paw edema & pleurisy induced by carrageenan injection), hyperalgesy (electronic von Frey), vasorelaxation (in vitro) & mean arterial pressure (MAP - in vivo), in rodents. We concluded that EEPA shows anti-inflammatory, analgesic & hypotensive properties.

   • Selon Monteiro LM (2023)

     Extrait Therefore, PA leaves are safe & present diuretic activity after acute & repeated dose administration over 7 days. is used in Brazilian traditional medicine to treat inflammation, chest pain, & anxiety.

   • Selon Salehi, B (2019)

     Extrait Among the functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, & neuro-pharmacological activities of the extracts & extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions, based on preclinical in vitro & in vivo studies, besides clinical studies. In traditional medicine, Piper species have been used worldwide to treat several diseases such as urological problems, skin, liver & stomach ailments, for wound healing, and as antipyretic & anti-inflammatory agents.

   • Selon Stein J (2022)

     Extrait (Piperaceae) is traditionally used due to its anti-inflammatory, analgesic, diuretic, & antiparasitic properties.

   • Selon Takeara R (2017)

     Extrait Many of these species are biologically active and have shown antitumor, antimicrobial, antioxidant, insecticidal, anti-inflammatory, antinociceptive, enzyme inhibitor, antiparasitic, antiplatelet, piscicide, allelopathic, antiophidic, anxiolytic, antidepressant, antidiabetic, hepatoprotective, amebicide & diuretic possibilities. Pharmacological studies of Piper species point toward the vast potential of these plants to treat various diseases.

2. 2

   Arthrose, rhumatisme, œdème

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2014)

     Extrait Therefore, this study aimed to evaluate the anti- inflammatory & analgesic effects of PA ethanolic extract (EEPA) & its isolated compound N-[7-(3′,4′-Methylenedioxyphenyl)-2(Z),4(Z)-hepta-dienoyl]pyrrolidine in experimental models of inflammation (paw edema & pleurisy induced by carrageenan injection), hyperalgesy (electronic von Frey), vasorelaxation (in vitro) & mean arterial pressure (MAP - in vivo), in rodents. is popularly known as "pariparoba" & has been used in folk medicine as an anti-inflammatory agent, however, there is only a study that showed the topical anti- inflammatory activity for such popular use.

   • Selon Salehi, B (2019)

     Extrait Among the functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, & neuro-pharmacological activities of the extracts & extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions, based on preclinical in vitro & in vivo studies, besides clinical studies. In traditional medicine, Piper species have been used worldwide to treat several diseases such as urological problems, skin, liver & stomach ailments, for wound healing, and as antipyretic & anti-inflammatory agents.

   • Selon Monteiro LM (2023)

     Extrait is used in Brazilian traditional medicine to treat inflammation, chest pain, & anxiety.

   • Selon Da-Silva Arrigo J (2016)

     Extrait Piper amalago (Piperaceae) has been used in folk medicine as an analgesic. Aim of the study: This study evaluated the anti-nociceptive, anti-hyperalgesic, anti-arthritic & anti-depressive activities of the ethanolic extract of EEPA & the amides N-[7-(3',4'-methylene-dioxyphenyl)-2(Z),4(Z)-heptadienoyl] pyrrolidine (1) & N-[7-(3',4'-methylenedioxyphenyl)-2(E),4(E)-heptadienoyl] pyrrolidine (2) obtained from PA in animal models.

   • Selon Stein J (2022)

     Extrait (Piperaceae) is traditionally used due to its anti-inflammatory, analgesic, diuretic, & antiparasitic properties.

3. 3

   Douleur, hyperalgie

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Da-Silva Arrigo J (2016)

     Extrait Piper amalago (Piperaceae) has been used in folk medicine as an analgesic. Materials & methods: Mice treated daily with EEPA (100mg/kg, p.o.) were assayed for 20 days for knee edema (micrometer measurement), mechanical hyperalgesia (analgesiometer analysis), heat sensitivity & immobility (forced swim test) in the Complete Freund's Adjuvant (CFA) model.

   • Selon Monteiro LM (2023)

     Extrait is used in Brazilian traditional medicine to treat inflammation, chest pain, & anxiety.

   • Selon Giovannini P (2017)

     Extrait Only nine species were reported in at least three studies: Cissampelos pareira L., Piper amalago L., Aristolochia trilobata L., Sansevieria Hyacinthoides (L.) Druce, Strychnos panamensis Seem., Dorstenia contrajerva L., Scoparia dulcis L., Hamelia patens Jacq., & Simaba cedron Planch. Available pharmacological data suggest different plant species may target different symptoms of snakebites, such as pain or anxiety, although more studies are needed to further evaluate the scientific basis for their use.

   • Selon Auteur (2014)

     Extrait Therefore, this study aimed to evaluate the anti- inflammatory & analgesic effects of PA ethanolic extract (EEPA) & its isolated compound N-[7-(3′,4′-Methylenedioxyphenyl)-2(Z),4(Z)-hepta-dienoyl]pyrrolidine in experimental models of inflammation (paw edema & pleurisy induced by carrageenan injection), hyperalgesy (electronic von Frey), vasorelaxation (in vitro) & mean arterial pressure (MAP - in vivo), in rodents. Both EEPA (100 mg/kg) & its isolated compound (3 mg/kg) exhibited antihyperalgesic effect in the model of mechanical hyperalgesia induced by carrageenan injection in mice.

   • Selon Stein J (2022)

     Extrait (Piperaceae) is traditionally used due to its anti-inflammatory, analgesic, diuretic, & antiparasitic properties.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.