Piper nigrum (Pwèv-nwè) : vertus médicinales en extraction alcoolique

Piper nigrum (Pwèv-nwè, Poivre noir, Black pepper) — famille Piperacées.

Synonymes scientifiques : Muldera multinrervis-Miq.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 25 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 93 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon ONYESIFE C O (2014)

     Extrait The effect of ethanol leaves extracts of Piper nigrum on some biochemical parameters in alloxan induced diabetic rats, was carried out. The result of this study indicates that ethanol leaves extract of Piper nigrum has hypoglycemic tendencies in diabetic conditions.

   • Selon Kaleem M (2005)

     Extrait Kaleem M et al, Protective effects of Piper nigrum & Vinca rosea in alloxan induced diabetic rats.

   • Selon Takeara R (2017)

     Extrait Many of these species are biologically active and have shown antitumor, antimicrobial, antioxidant, insecticidal, anti-inflammatory, antinociceptive, enzyme inhibitor, antiparasitic, antiplatelet, piscicide, allelopathic, antiophidic, anxiolytic, antidepressant, antidiabetic, hepatoprotective, amebicide & diuretic possibilities. Pharmacological studies of Piper species point toward the vast potential of these plants to treat various diseases.

2. 2

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bai XP (2011)

     Extrait The findings indicate that the ethanol extract of PN root is an efficient hepatoprotective & antioxidant agent against 4-CCl-induced liver injury,. The aim of this study was to investigate the effect of Piper nigrum L.

   • Selon Patel JA (2009)

     Extrait Hepatoprotective activity of Piper longum traditional Milk extract on carbon tetrachloride induced liver toxicity in Wistar rats.

   • Selon Kavitha M (2011)

     Extrait Ethanolic extract from the leaves of Melia Azadirachta, seeds of Piper longum & whole plant of Eclipta alba at a dose level of 50 mg/kg body weight was administered orally daily once for 14 days. The Poly-herbal ethanolic extract (PHEE) was evaluated for its anti-hepatotoxic potential against carbon tetrachloride (CCL 4) induced hepatic damage in male albino rats.

   • Selon PANDA S (2003)

     Extrait An investigation was made to evaluate the effects of water & ethanol extracts of Piper nigrum L. Rather, the latter extract appeared to be antithyroidic & antiperoxidative in nature as it could decrease serum thyroid hormone concentrations & hepatic lipid peroxidation, respectively.

   • Selon Gupta RA (2015)

     Extrait & Piper nigrum Linn., is a plant alkaloid with a long history of medicinal use. Piperine exhibits antidepressant, hepatoprotective, antimetastatic, antithyroid, immunomodulatory, antitumor & anti-inflammatory activities, however its therapeutic potential in amelioration of ulcerative colitis & the underlying mechanism for anti-inflammatory activity remains unknown.

3. 3

   Arthrite rhumatoide

   Partie usitée : Fruit. Association synergique mentionnée : Curcuma longa-Rhiz, association synergique avec VITEX NEGUNDO-L (Feuille), Zingiber officinale-Rhiz.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon KHARAT SS (2024)

     Extrait This project aims to develop a polyherbal emulgel, a topical formulation, utilizing the synergistic effects of Vitex negundo (leaves), Curcuma longa (Rhizoma), Piper nigrum (fruit), & Zingiber officinale (rhizoma), known for their anti-inflammatory, analgesic, & antioxidant properties. Vitex negundo (Nirgundi) possesses anti-inflammatory & analgesic properties, while Curcuma longa (Turmeric) is known for its potent anti-inflammatory & antioxidant effects.

   • Selon Pratibha N (2004)

     Extrait A novel, safe polyherbal formulation (Aller-7/NR-A2) has been developed for the treatment of allergic rhinitis using a unique combination of extracts from seven medicinal plants including Phyllanthus Emblica, Terminalia chebula, Terminalia bellerica, Albizia lebbeck, Piper nigrum, Zingiber officinale & Piper longum. Aller-7 also exhibited a dose-dependent (150-350 mg/kg) anti-inflammatory effect against Freund's adjuvant-induced arthritis in Wistar Albino rats & an approximately 63% inhibitory effect was observed at a dose of 350 mg/kg.

   • Selon Tasleem F (2014)

     Extrait To evaluate & compare the analgesic & anti-inflammatory activity of pure compound, piperine along with hexane & ethanol extracts of Piper nigrum fruit in mice & rats. While the anti-inflammatory activity was evaluated by carrageenan-induced paw inflammation in rats.

   • Selon Salehi, B (2019)

     Extrait Among the functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, & neuro-pharmacological activities of the extracts & extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions, based on preclinical in vitro & in vivo studies, besides clinical studies. In traditional medicine, Piper species have been used worldwide to treat several diseases such as urological problems, skin, liver & stomach ailments, for wound healing, and as antipyretic & anti-inflammatory agents.

   • Selon PRASAD K (2015)

     Extrait The result showed a higher stabilization potential in ethanolic extract of Piper nigrum seeds which showed 55.17±1.56, 64.00±1.18 & 70.50±0.96 percentage inhibition of mast cell degranulation. In the present study a comparative effect of mast cell stabilizing activity of different plant extracts Momordica dioica fruit pulp (family-Cucurbitaceae), Cuminum cyminum seeds (family - Apiaceae), Piper nigrum seeds (family-Piperaceae), Boerhaavia diffusa roots (family - Nyctaginaceae.), Withania somnifera roots (family-Solanaceae), Mangifera indica leaves (Anacardiaceae), Plantago ovata (Plantaginaceae) was carried out.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.