Plumeria rubra (Franjipanié wouj) : vertus médicinales en extraction alcoolique

Plumeria rubra (Franjipanié wouj, Frangipanier rouge) — famille Apocynacées.

Synonymes scientifiques : -----.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 19 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome hépatique

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Muruganantham S (2014)

     Extrait The present study has been performed experimentally by in vitro method to examine the anti-cancer activity of various concentrations of ethanolic extract of flowers of Plumeria rubra. The ethanolic extract of flowers of PR was tested for its anti-cancer activity against liver cancer HePG2 cell line by MTT assay.

   • Selon Bihani T (2021)

     Extrait The plant possesses a wide range of pharmacological activities present namely antibacterial, antiviral, anti-inflammatory, antipyretic, antidiabetic, hepatoprotective, anticancer, anthelmintic, antifertility & many other activities. (Apocynaceae) is a deciduous, commonly ornamental, tropical plant grown in home premises, parks, gardens, graveyards, because of its beautiful & attractive flowers of various colors & size.

   • Selon Rahman H (2014)

     Extrait Plumeria species could be a new source of drugs for the treatment of colon cancer & hyperlipidemic conditions due to higher antioxidant potential & phenolic content which was revealed from the study. DPPH assay of methanolic extract of Plumeria revealed that 81% & 72% inhibition by PA & PR respectively & the total phenolic content was found as 173.9 µg ml-1 & 167.3 µg ml-1.

   • Selon Banu-Rekha J (2011)

     Extrait .The ethanolic extract of leaves of Plumeria rubra (Linn) were evaluated for their anti cancer activity against Ehrlich Ascites Carcinoma (EAC) in Swiss albino mice. The anti cancer activity of PR was examined by determining the tumor volume, tumor cell count, viable tumor cell count, non viable tumor cell count, mean survival time & increase in life span in experimental animal models.

   • Selon Muhtadi M (2021)

     Extrait rubra flowers with an IC50 value of 150, 20 ppm while in the FRAP method the highest activity was in P. This study aims to determine the antioxidant activity of Plumeria alba L & Plumeria rubra L.

2. 2

   Diabète mellitus de type II

   Partie usitée : Fleur. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ahmed AS (2017)

     Extrait (Piperaceae) & flowers of Plumeria rubra L. Inhibition of intestinal α-amylase and α-glucosidase is an important strategy to regulate diabetes mellitus (DM).

   • Selon Zhang SN (2020)

     Extrait A decoction of Plumeria rubra flowers has been used traditionally for the treatment of diabetes in China & Mexico. Chemical investigations on the bioactive constituents of these flowers led to the isolation of 30 compounds, including the four new compounds, one iridoiod (1), two triterpenoids (4, 5), & a long-chain δ-lactone (16).

   • Selon Yadav AV (2022)

     Extrait the current investigation analysed the effect of combination of standardized hydroalcoholic extracts of Asparagus racemosus (AR), Centella asiatica (CA) & Plumeria rubra (PR) on glibenclamide (GB) administered in experimentally induced diabetic nephropathy (DN) in Wistar rats. Co-administration of ACP (400mg/kg) with GB (5mg/kg) significantly (p<0.01) decreased BUN, creatinine, uric acid, significantly increased (p<0.05) SOD, significantly (p<0.01) decreased MDA, significantly increased (p<0.05) serum insulin when compared with diabetic control.

   • Selon Merina A (2019)

     Extrait Antioxidant & hypolipidemic activity of the flovone glycoside isolated from Plumeria rubra was carried in alloxan induced hyperglycemic rats.

   • Selon Bihani T (2021)

     Extrait The different parts of the plant are used traditionally to treat various diseases & conditions like leprosy, inflammation, diabetic mellitus, ulcers, wounds, itching, acne, toothache, earache, tongue cleaning, pain, asthma, constipation & antifertility. The plant possesses a wide range of pharmacological activities present namely antibacterial, antiviral, anti-inflammatory, antipyretic, antidiabetic, hepatoprotective, anticancer, anthelmintic, antifertility & many other activities.

3. 3

   Stress oxydatif

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ahmed AS (2017)

     Extrait Hence, methanol & aqueous extracts of the aforementioned plants were evaluated for their in vitro α-glucosidase and α-amylase inhibition at 1 mg/mL & quantification of their antioxidant properties (DPPH, FRAP tests, total phenolic & total flavonoids contents). rubra were 10.41 (0.03), 95.19 (0.01), & -2.92 (0.03), while the methanol extracts exhibited % inhibition 13.73 (0.02), 92.77 (0.01), & -0.98 (0.01), respectively.

   • Selon Muhtadi M (2021)

     Extrait This study aims to determine the antioxidant activity of Plumeria alba L & Plumeria rubra L. rubra leaves with an antioxidant activity value of 79.75 mg AAE / g extract.

   • Selon Merina A (2019)

     Extrait Antioxidant & hypolipidemic activity of the flovone glycoside isolated from Plumeria rubra was carried in alloxan induced hyperglycemic rats. Antioxidant activity of the drug was also confirmed through in vitro studies.

   • Selon Yadav AV (2022)

     Extrait the current investigation analysed the effect of combination of standardized hydroalcoholic extracts of Asparagus racemosus (AR), Centella asiatica (CA) & Plumeria rubra (PR) on glibenclamide (GB) administered in experimentally induced diabetic nephropathy (DN) in Wistar rats. Results: ACP along with GB improved the derailed glycaemic status, renal biochemical, oxidative stress parameters in animals.

   • Selon Rahman H (2014)

     Extrait Plumeria species could be a new source of drugs for the treatment of colon cancer & hyperlipidemic conditions due to higher antioxidant potential & phenolic content which was revealed from the study. rubra were tested for in vitro antioxidant potential, cytotoxicity & hypolipidemic activities.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.