Portulaca oleracea (Koupié) : vertus médicinales en extraction alcoolique

Portulaca oleracea (Koupié, Poupié, Pourpier, Purslane) — famille Portulacacées.

Synonymes scientifiques : Portulaca oleracea var. Parviflora-(Haw)-Griseb, P. Oleracea var. Parviflora. Griseb, P. Parviflora-Haw, P Parviflora var. macrantha-Eggers, P. Oleracea var. micrantha. Eggers.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 28 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 101 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Hépatotoxicité : foie gras non alcoolique, induite par l’acétaminophène (Doliprane)

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Liu XF (2015)

     Extrait Acetaminophen-induced liver injury represents the most frequent cause of drug-induced liver failure in the world. The results demonstrated that PO was an effective anti-oxidative agent, which could, to some extent, reverse APAP-induced hepatotoxicity by regulating the reactive oxygen species (ROS) in the liver of mice.

   • Selon Damavandi RD (2021)

     Extrait At the end of study, no significant changes were observed in liver steatosis grade, insulin, liver enzymes, total bilirubin, lipid profile, & blood pressure between the two groups. The aim of the present study was to examine the effect of PO hydroalcoholic extract in patients with non-alcoholic fatty liver disease (NAFLD).

   • Selon Milkarizi N (2024)

     Extrait Portulaca oleracea exhibit antioxidant, anti-inflammatory, & hepatoprotective effects. Liver steatosis & fibrosis were assessed using elastography along with liver function & metabolic tests, blood pressure measurements, body composition analysis & dietary records pre-& post-intervention.

   • Selon Shi H (2014)

     Extrait In present study, carbon tetrachloride (CCl4) was used to induce acute liver damage in mice & the protective effects of ethanol extract of Portulaca Oleracea (PO) were examined. In addition, in cultured hepatic cells, PO increased the NF-κB luciferase reporter gene activity and upregulated the level of phosphorylation of p65, but had no effects on mice liver SOD activity & MDA level.

   • Selon Shi H (2014)

     Extrait In present study, carbon tetrachloride (CCl4) was used to induce acute liver damage in mice & the protective effects of ethanol extract of Portulaca Oleracea L. In addition, in cultured hepatic cells, PO increased the NF-κB luciferase reporter gene activity and upregulated the level of phosphorylation of p65, but had no effects on mice liver SOD activity & MDA level.

2. 2

   Diabète mellitus de type I

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Damavandi RD (2021)

     Extrait Purslane (Portulaca oleracea L.) is the richest green leafy vegetable source of omega-3, especially alpha linolenic acid (ALA). Compared with baseline, alanine aminotransferase (ALT) (-9 [-17, 0.50] mg/dl; p = .007), aspartate aminotransferase (AST) (-4 [-10, -0.50] mg/dl; p = .001), gamma glutamyl transferase (GGT) (-6.21 ± 9.85 mg/dL; p < .001), fasting blood glucose (FBG) (-8 [-11, -1.50] mg/dl; p < .001) insulin resistance (-0.95 ± 2.23; p = .020), triglyceride (-20 [-67.50, 3.50] mg/dl; p = .010), & low-density lipoprotein cholesterol (LDL-C) (-5 [-12, -1] mg/dl; p < .001) decreased significantly in the PO group.

   • Selon MIAO L (2023)

     Extrait Male C57BL/6 mice had 14-week ad libitum access to a high-fat rodent diet containing 60% kcal% fat to induce obesity & diabetes whereas purslane extract (200 mg/kg/day) was administered during the last 4 weeks via intragastric gavage. This study supported that purslane protected endothelial function, & inhibited ER stress and oxidative stress in vasculature through AMPK/eNOS activation, revealing its therapeutic potential against vascular complications in diabetes.

   • Selon Jalali J (2022)

     Extrait This disorder is a significant risk factor for insulin resistance, diabetes mellitus, cardiovascular disease incidence, & mortality. Jalali J et al, Ameliorative effects of Portulaca oleracea L.

   • Selon Rakhshandeh (2022)

     Extrait Based on the anti-diabetic, antioxidant, & anti-hyperlipidemic potential of Portulaca oleracea (PO), this study aimed to evaluate the protective effect of this plant extract on streptozotocin-induced type-I-diabetes-associated reproductive system dysfunction & inflammation. Results: Our results showed that streptozotocin-induced diabetes significantly increased food & water consumption; increased glucose, MDA, TGF-β1, & TNF-α levels; & decreased the seminiferous tubules diameter, sperm count & motility, levels of LH, testosterone, total thiol, VEGF, & SOD activity.

   • Selon Ebrahimian Z (2022)

     Extrait MetS is the best-known risk factor for type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), & obesity. Portulaca oleracea L.

3. 3

   Infection bacterienne : Pseudomonas aeruginosa, Salmonella Typhimurium, Proteus mirabilis, Klebsiella pneumoniae & Enterobacter aerogenes

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nayak BH (2014)

     Extrait The apigenin so-obtained was subjected to antibacterial activity on five pathogenic bacterial strains like Pseudomonas aeruginosa, Salmonella Typhimurium, Proteus mirabilis, Klebsiella pneumoniae & Enterobacter aerogenes; among all the bacterial strains, S Typhimurium & P mirabilis have shown maximum diameter of inhibition zone for flavonoid & remaining bacterial strains have shown moderate diameter of inhibition zone when compared with control values & respectively. The minimum inhibition concentration (MIC) for the flavonoid for all tested bacterial strains was found to be >4 mg per mL.

   • Selon WANG M (2023)

     Extrait This article systematically reviews the extraction & purification methods, chemical structure, chemical modification, biological activity & other aspects of polysaccharides from purslane collected in the Chinese Pharmacopoeia, Flora of China, Web of Science, PubMed, Baidu Scholar, Google Scholar & CNKI databases in the last 14 years, using the keywords "Portulaca oleracea L. Portulaca oleracea L.

   • Selon Auteur (2006)

     Extrait Study on Antimicrobial Effect of Flavonoids from Portulaca oleracea L.

   • Selon Liu G (2023)

     Extrait Previous studies have shown that Portulaca oleracea L. In summary, this study reports a botanical extract that can inhibit SA in vitro & in vivo, indicating the potential use of OAPO to prevent and control SA infection in the near future.

   • Selon Liu ZT (2023)

     Extrait In this study, a response surface methodology was employed to optimize the extraction conditions for total flavonoids (TF) from Portulaca oleracea. Notably, the extracts obtained through ultrasound-assisted extraction exhibited higher total flavonoid content, antibacterial activity, and antioxidant activity compared to those obtained through conventional solvent extraction.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.