Quassia amara (Kina) : vertus médicinales en extraction alcoolique

Quassia amara (Kina, Kininn’Kayenn’, Quina, Quinine-de-Cayenne, Cayenne quinine) — famille Rubiacées.

Synonymes scientifiques : Quassia officinalis Rich..

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 5 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 66 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Arthrose, arthrite, rhumatisme, oedème

   Partie usitée : Écorce.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon TOMA W (2003)

     Extrait We evaluated the possible antiedematogenic, antinociceptive and/or sedative effects of four different extracts obtained from the bark of Quassia amara namely, 70% ethanol (70EtOH), 100% ethanol (100 EtOH), dichloromethane (DCM) & hexane extracts (HEX). However, when administered intraperitoneally, the HEX extract decreased the paw edema induced by carrageenan, showed antinociceptive effects on the hot-plate test & on acetic acid-induced writhing, & showed sedative effects on pentobarbital-induced sleep.

   • Selon Balakrishna A (2022)

     Extrait Various studies indicate that QA possess different biological properties namely anti-diabetic, anti-inflammatory, anti-hyperglycemic, anti-leishmanial, anti-malarial, anti-nociceptive, anti-ulcer, anti-fertility & sedative. Quassia amara Linn., is a shrub & world widely known as 'bitter-wood' belongs to Simaroubaceae family.

   • Selon Kunnathodi F (2015)

     Extrait Quassin is the major secondary chemical compound in it, which is under investigation as an anti-malarial compound.

   • Selon Reya E (2017)

     Extrait Quassia amara Linn., famous as bitterwood or quassia, is a neotropical forest shrub indigenous to Northern Brazil. Indian Quassia, mostly seen in northern & eastern states, is a source of numerous compounds including b – carbonile, cantin-6 alkaloids & primarily, the bitter compounds known as quassinoids.

   • Selon Raji Y (s.d.)

     Extrait The effect of Quassia amara extract & two isolated compounds from the extract, quassin & 2- methoxycathine-6-one on haematological parameters was studied in rats. The results suggest that quassia extract possesses Antianaemic property.

2. 2

   Infection fongique : C.andida albicans, C. parapsilosis, C. glabrata , C. krusei, Malassezia furfur

   Partie usitée : Écorce.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Diehl C (2016)

     Extrait Contrarily, QWE had no effect on the growth of Chlamydia trachomatis, but uniquely altered the morphology & quantity of chlamydial inclusions.To the best of our knowledge, this is the first time that QWE is shown to have antiparasitic activity on Trichomonas vaginalis & Demodex spp, an antifungal activity on Malassezia furfur & Candida spp & an antibacterial activity on P. krusei, the latest at a lesser extent, & Malassezia furfur isolated from samples of infected patients, inhibiting the growth of fungi in both a time- & dose-dependent manner.The antibacterial activity of QWE was demonstrated in cultures of P.

   • Selon AJAIYEOBA EO (2003)

     Extrait AJAIYEOBA EO et al, Antibacterial & antifungal activities of Quassia undulata & Quassia amara extracts in vitro.

   • Selon Obembe OO (2020)

     Extrait Quassia amara stem bark has been reputed to have strong antimalarial, antimicrobial, antiulcerative & amoebicidal properties. (2009) — extrait : With respect to Plasmodium falciparum erythrocytic stages, SkD was almost inactive on earlier & later parasite stages, but potently active at the 30th h of parasite cycle when DNA replicates in mature trophozoites. Quassinoid compound Simalikalactone D (SkD) has been shown to be one of the molecules responsible for the antiplasmodial activity of a watery preparation made out of juvenile fresh leaves of this plant.

3. 3

   Infection bactérienne : P. acnes & coagulase- positive Staphylococci

   Partie usitée : Écorce.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon AJAIYEOBA EO (2003)

     Extrait AJAIYEOBA EO et al, Antibacterial & antifungal activities of Quassia undulata & Quassia amara extracts in vitro.

   • Selon Diehl C (2016)

     Extrait acnes & coagulase- positive Staphylococci where the growth of the bacteria was reduced in a significant manner (p<0.05) & at a lesser extent in cultures of coagulase-negative Staphylococci where the growth inhibition was not statistically significant. Quassia amara is a plant of the family Simaroubaceae of Northern Brazilian origin.Its use in folk medicine is widespread, especially as an antiparasitic, antifungal & antibacterialagent.

   • Selon Obembe OO (2020)

     Extrait Quassia amara stem bark has been reputed to have strong antimalarial, antimicrobial, antiulcerative & amoebicidal properties.

   • Selon Evans DA (1991)

     Extrait Crushed aqueous extracts of leaf, wood, bark & flowers of Quassia amara showed antilarval activity against C quinquefasciatus. This compound is an unsaturated lactone & it gave a positive response to the Legal test, characteristic of unsaturated lactones. (2009) — extrait : With respect to Plasmodium falciparum erythrocytic stages, SkD was almost inactive on earlier & later parasite stages, but potently active at the 30th h of parasite cycle when DNA replicates in mature trophozoites. Quassinoid compound Simalikalactone D (SkD) has been shown to be one of the molecules responsible for the antiplasmodial activity of a watery preparation made out of juvenile fresh leaves of this plant.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.