Rhodiola rosea (Rhodiola) : vertus médicinales en extraction alcoolique

Rhodiola rosea (Rhodiola, Racine dorée, Golden root) — famille Crassulacées.

Synonymes scientifiques : Rhodiola roanensis (Britton) Britton, Sedum Rhodiola DC., S. roanense Britton, S. rosea (L.) Scop., S. rosea var. roanense (Britton) A. Berger.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 203 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome de Lewis

   Partie usitée : Rhizome. Profil pharmacologique documenté : Cyclophosphamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon BERNATIONENE J (2023)

     Extrait The roots & rhizomes of Rhodiola rosea L. Recent studies indicate that RR may be used to treat diabetes, cancer, & a variety of cardiovascular & neurological disorders such as Alzheimer's & Parkinson's diseases.

   • Selon ZHANG Y (2019)

     Extrait To explore the anti-tumor immune function of the Tibetan medicine Rhodiola rosea L. Methods: Lewis’s lung cancer-bearing mice were randomly divided into normal saline group, 500 mg/kg RRL ethanol extract treatment group, & 10 mg/kg cyclophosphamide (CTX) treatment group.

   • Selon ZHANG X (2020)

     Extrait Methods: The effects of RR on NSCLC were examined in Lewis lung carcinoma (LLC) tumor-bearing mice models. (RR), a well-known traditional Chinese medicine (TCM), has been turned out to be effective in anti-lung cancer therapy, but its molecular mechanism of action has not been clearly understood.

   • Selon Li Y (2017)

     Extrait Rhodiola rosea extracts have been used as a dietary supplement in healthy populations, including athletes, to non-specifically enhance the natural resistance of the body to both physical & behavior stresses for fighting fatigue and depression. Recent findings: In addition to its multiplex stress-protective activity, RR extracts have recently demonstrated its anti-aging, anti-inflammation, Immunostimulating, DNA repair & anti-cancer effects in different model systems.

   • Selon WANG S (2023)

     Extrait Pharmacological studies have demonstrated that Rosavin has a variety of biological activities, including antioxidant, lipid-lowering, analgesic, antiradiation, antitumor & immunomodulation effects.

2. 2

   Neuroinflammation

   Partie usitée : Rhizome.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gan Z (2024)

     Extrait This study undertakes a systematic review of both domestic & international literature, assessing the research advancements a chemical functional value of polysaccharides derived from Rhodiola rosea. This genus contains key compounds such as ginsenosides, polysaccharides, & flavonoids, which possess anti-inflammatory, antioxidant, hypoglycaemic, immune-enhancing, & anti-hypoxic properties.

   • Selon Pooja Bawa A.S (2009)

     Extrait Inhibition of nystatin induced oedema & phospholipase A2 suggested that membrane stabilization could be the most probable mechanism of action of RTE in anti-inflammation. The anti-inflammatory activity was determined through carrageenan-induced paw oedema, formaldehyde-induced arthritis nystatin-induced paw oedema in rat model.

   • Selon NABAVI SF (2016)

     Extrait The roots of RR possess a wide range of pharmacological activities such as antioxidant, anti-inflammatory, anticancer, cardioprotective, & neuroprotective effects that are because of the presence of different phytochemicals such as phenols & flavonoids. A plethora of studies report that RR has potent neuroprotective effects through the suppression of oxidative stress, neuro-inflammation, & excitotoxicity in brain tissues & antagonism of oncogenic p21-activated kinase.

   • Selon Li Y (2017)

     Extrait Rhodiola rosea extracts have been used as a dietary supplement in healthy populations, including athletes, to non-specifically enhance the natural resistance of the body to both physical & behavior stresses for fighting fatigue and depression. Recent findings: In addition to its multiplex stress-protective activity, RR extracts have recently demonstrated its anti-aging, anti-inflammation, Immunostimulating, DNA repair & anti-cancer effects in different model systems.

   • Selon LI Y (2021)

     Extrait The possible mechanisms of RRC are largely through antioxidant, anti-apoptosis activities, anti-inflammatory, repressing lipid peroxidation, antigliosis, & alleviating the pathological blood Brain barrier damage. Pooled preclinical data showed that compared with the controls, RRC could improve NFS (Zea Longa (p < 0.01), modified neurological severity score (mNSS) (p < 0.01), rotarod tests (p < 0.01), IV (p < 0.01), as well as brain edema (p < 0.01).

3. 3

   Infection bactérienne : Escherichia coli, Listeria monocytogenes, Staphylococcus aureus, Pseudomonas aeruginosa

   Partie usitée : Rhizome.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ahmed M (2015)

     Extrait Rhodiola rosea, a medicinal plant with demonstrated adaptogenic properties, has recently been reported to contain active compounds with antimicrobial activity. Serum from both groups collected 15 min post-marathon significantly promoted the growth of Escherichia coli in culture as compared to serum collected the day before the marathon (P = 0.003, all subjects).

   • Selon Auteur (2018)

     Extrait The chemical profiles were determined by High-performance Liquid Chromatography with a diode-array detector (HPLC-DAD) & Gas chromatography-mass spectrometry (GC-MS), antioxidant activity by (1,1-Diphenyl-2-picrylhydrazyl) Scavenging Capacity Assay (DPPH), (2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) Scavenging Capacity Assay (ABTS) & Ferric Reducing Antioxidant Power Assay (FRAP) & antimicrobial properties were expressed as minimum inhibitory concentration (MIC) & minimum bacterial concentration (MBC) values following the broth microdilutions method. Roseroot (Rhodiola rosea L.) belongs to plants revealing adaptogenic properties, which are attributed to the presence of specific phenolic compounds & are reflected mainly as antioxidant activity.

   • Selon Zdanowska (2009)

     Extrait Zdanowska et al, the effect of Rhodiola rosea extracts on the bacterial infection in mice.

   • Selon CUI Q (2018)

     Extrait The time-of-addition experiments suggest that, mechanistically, the RR extract & the effective compounds act at an early step in the infection cycle following initial cell attachment, but prior to viral/cell membrane fusion. Traditional Chinese medicines (TCMs) represent a huge reservoir of bioactive chemicals & many TCMs have been shown to have antiviral activities.

   • Selon Wang, H (2009)

     Extrait The aim of this study was to investigate the antiviral effects of salidroside, a major component of Rhodiola rosea L. In conclusion, salidroside possesses antiviral activities against CVB3 and it may represent a potential therapeutic agent for viral myocarditis.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.