Ricinus communis (Fèy-grenn’) : vertus médicinales en extraction alcoolique

Ricinus communis (Fèy-grenn’, PalmaKristi, Karapat, Risen, Feuille-à-graine, Palma-Christi, Carapate, Ricin, Seed-leaf, Castor oil plant) — famille Euphorbiacées.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 42 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Racine.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shokeen P (2008)

     Extrait We investigated the antidiabetic activity of 50% ethanolic extract of roots of Ricinus communis (RCRE) along with its Bioassay-guided purification. communis seems to have a promising value for the development of a potent Phytomedicine for diabetes.

   • Selon Gad-Elkareem M (2019)

     Extrait This study aimed to investigate the antidiabetic effect of ethanolic & aqueous-ethanolic extracts of wild Ricinus communis leaves in streptozotocin (STZ) induced diabetic rats. Diabetic rats were administered orally with the mentioned extracts at doses of 300 & 600 mg/kg/BW for 14 days & the obtained results of different biochemical parameters were compared with normal control, diabetic control & standard drug Glibenclamide (5 mg/kg/BW).

   • Selon Hassan HN (2019)

     Extrait In this study, we performed whole-genome gene expression profiling using RNA-Seq to determine the differentially expressed genes in a mammalian cell line after exposure to Ricinus Communis leaf extract & elucidate their pharmacological effects in order to support its ethnomedicinal uses. Various genes involved in cancer, inflammation, atherosclerosis & diabetes were found to be differentially regulated after exposure to sub-lethal concentrations of the RC extract in MCF7 cells.

   • Selon Abdul WM (2018)

     Extrait communis harbours phytochemicals which have been shown to target peroxisome proliferator activated receptor (PPAR), nuclear factor NF- κ -B, cytochrome p450, P38 Mitogen-activated protein kinases kinase (p38 MAPK), tumor protein P53, B-cell lymphoma-extra-large (Bcl-xL) and vascular endothelial growth factor receptor-2 (VEGFR-2). These phytochemicals have been responsible for pharmacological and therapeutic effects, including anticancer, antimicrobial, insecticidal, antioxidant, anti-diabetic, antinociceptive, anti-inflammatory, bone regenerative, analgesic & anticonvulsant activity.

2. 2

   Cancer : traitement adjuvant du carcinome colorectal, mammaire et hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Aslani MR (2007)

     Extrait Pathology revealed severe gastroenteritis, cardiac haemorrhage & necrosis, hepatic necrosis & acute tubular necrosis in kidneys.

   • Selon Majumder M (2019)

     Extrait Here, we report the anti-cancer efficacy of Ricinus communis fruit extract (RCFE) using estrogen positive MCF-7 & highly aggressive, triple negative MDA-MB-231 breast cancer cells. Overall, this study for the first time demonstrates the anti-cancer efficacy of the fruit extract of common castor plant which can be proposed as a potent candidate for the treatment of breast cancer.

   • Selon Soto KM (2069)

     Extrait communis) leaves (AuNPsCE) ethanolic extracts in human HT29 & SW480 colorectal cancer cells. communis extracts to synthesize AuNPs, displaying a stronger antiproliferative effect than AuNPsCS.

   • Selon Al-Mamun AM (2016)

     Extrait Ricinus communis (Euphorbiaceae) has previously been reported to possess analgesic, antihistamine, antioxidant & anti-inflammatory activities. communis seed protein on EAC cells was determined by hemocytometer counting using trypan blue dye & DAPI (4΄, 6-diamidino-2-phenylindole) staining was used to assess apoptotic cells.

   • Selon Prakas E (2013)

     Extrait The objective of the present study was to evaluate the in-vitro anti- cancer effects of ethanolic extract of three plant species namely Ricinus communis, Euphorbia helioscopia, Jatropha curcas of the family Euphorbiaceae by SRB assay against seven human cancer cell lines. Colon cancer cell line (Colon HT-29, SW-20, SiHa, Colon 502717), Liver cancer cell line (Hep-2), Breast cancer cell line (T-47D), Cervix cancer cell line OVCAR-5, Prostate cancer cell line (PC-3) & Lungs (AF-49).

3. 3

   Infection bacterienne & fongique : Pseudomonas aeruginosa, Candida albicans

   Partie usitée : Racine.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Santos PM (2018)

     Extrait cereus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella choleraesuis, Candida albicans & C. The objective of this study was to apply a detailed multiplatform-based metabolite profiling approach to identify antioxidant & antimicrobial compounds in Ricinus communis extracts.

   • Selon Abbas M (2018)

     Extrait communis along with antioxidant & antimicrobial activities. communis methanolic extracts revealed mild mutagenicity against TA98 (range 1975 ± 67 to 2628 ± 79 revertant colonies) & TA100 (range 2773 ± 92 to 3461 ± 147 revertant colonies) strains and these values were 3267 ± 278 & 4720 ± 346 revertant colonies in case of TA98 & TA100 positive controls, respectively.

   • Selon Manaf AA (1996)

     Extrait Antiviral activity against both viruses was present in the extracts from Calotropis gigantea, Costus speciosus, Eugenia micheli, Hedyotis auricularia, Mentha arvensis, Orthosiphon aristatus, Polygonum minus, Ricinus communis (MIG: 0.002-0.1 mg/ml). Antiviral activity was tested against the herpès simplex type-1 (HSV-1) & Vesicular stomatitis (VSV) viruses & cytotoxicity was assayed using the HeLa cell line.

   • Selon Al-Mamun AM (2016)

     Extrait In vitro susceptibility of four human pathogenic bacteria including Escherichia coli, Pseudomonas aeruginosa, Enterobacter aerogenes & Staphylococcus aureus was detected using disk diffusion assay, & minimum inhibitory concentration (MIC) value was determined using micro-dilution method. Ricinus communis (Euphorbiaceae) has previously been reported to possess analgesic, antihistamine, antioxidant & anti-inflammatory activities.

   • Selon Donkor AM (2018)

     Extrait Antibacterial activities of the extracts of three medicinal plants, Senna alata, Ricinus communis & Lannea barteri from two different extractants were studied. Bacteria strains such as Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae & Escherichia coli are known wound & skin disease causing bacteria.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.