Schinus terebenthifolius (Pwèv-Brézil) : vertus médicinales en extraction alcoolique

Schinus terebenthifolius (Pwèv-Brézil, Poivre du Brésil, Brazilian pepper) — famille Anacardiacées.

Synonymes scientifiques : Schinus terbinthifolia var. damaziana-Beauverd.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 14 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 57 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Hépatite, cirrhose, stéatose hépatique, désintoxication hépatique

   Partie usitée : parties aeriennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon KHALIL W (2015)

     Extrait The present study was conducted to investigate the curative & protective effects of Schinus terebenthifolius ethanolic extract against CCl4 -induced acute hepatotoxicity in rats. CCl4 increased liver enzyme leakage, oxidative stress, hepatic apoptosis, DNA oxidation, & inflammatory markers.

   • Selon Abdou RH (s.d.)

     Extrait The present study was conducted to investigate the curative & protective effects of Schinus terbenthifolius ethanolic extract against CCl4 -induced acute hepatotoxicity in rats. Results: CCl4 increased liver enzyme leakage, oxidative stress, hepatic apoptosis, DNA oxidation, & inflammatory markers.

   • Selon Dos Santos da Rocha P (2019)

     Extrait After showing no acute toxicity in vivo, MESL was able to lower postprandial glycemia after glucose overload in normoglycemic mice as well as the water & feed intake, liver weight, glycemia & serum levels of glycated hemoglobin, aspartate transaminase (AST) & alanine transaminase (ALT) in diabetic mice.

   • Selon Salem MZM (2018)

     Extrait The toxicity against the growth of Acinetobacter baumannii, Bacillus subtilis, Escherichia coli, Micrococcus flavus, Pseudomonas aeruginosa, Sarcina lutea, & Staphylococcus aureus was determined with measuring the inhibition zones (IZs) using the disc diffusion method at the concentrations from 125 to 2000 μg/mL, also, the minimum inhibitory concentrations (MICs) using 96-well micro-plates & ranged from 4 to 2000 μg/mL. aeruginosa with MIC values of 16 μg/mL & 32 μg/mL, the ACE showed broad activity against the studied bacterial pathogens with MIC values ranged from of 4-128 μg/mL against the studied bacterial isolates, while HexE, however, showed weak antibacterial activity.

   • Selon El-Nashar HAS (2022)

     Extrait Besides, some Schinus species & their isolated active compounds showed important biological activities such as antibacterial, antifungal, insecticidal, antiparasitic, analgesic, cytotoxic, antitumor, antioxidant, antihypertensive, anti-inflammatory, antimycobacterial, anti-Parkinson, anti-allergic, antiviral, wound healing, chemoprotective, anthelmintic & hepatoprotective. Traditionally, Schinus plants are used to alleviate several & diverse diseases including rheumatism, hypertension, ulcers, gastric distress, menstrual disorders, gonorrhea, bronchitis, gingivitis, conjunctivitis, dysentery, wounds, urinary tract, & eye infections.

2. 2

   Cancer : traitement adjuvant du carcinome leucémique & mammaire

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bendaoud J (2010)

     Extrait Essential oils were also evaluated for their anticancer activities against human breast cancer cells (MCF-7). & Schinus terebinthifolius Raddi originating from southern of Tunisia & analyzed by GC-FID & GC-MS.

   • Selon Bulla MK (2015)

     Extrait Schinus terebinthifolius is a plant rich in phenolic compounds, which have antioxidant properties & can provide new opportunities for treatment & prevention of diseases mediated by ultraviolet radiation like photoaging & skin cancer.

   • Selon Santana JS (2012)

     Extrait These compounds, including hydrogenation (pinane) & epoxydation (α-pinene oxide) derivatives from α-pinene, were tested in vitro against murine melanoma cell line (B16F10-Nex2) & human melanoma (A2058), breast adenocarcinoma (MCF7), leukemia (human leukemia (HL-60) & cervical carcinoma (HeLa) cell lines. The crude essential oil showed cytotoxic effects in several cell lines, mainly on leukemia & human cervical carcinoma.

   • Selon Cruz-Rosas E (2015)

     Extrait Additionally, ST-70 inhibited synovial interleukin (IL)-6, IL-1β, keratinocyte-derived chemokine (CXCL1/KC) & Tumor Necrosis Factor (TNF)-α production at 6h & CXCL1/KC & IL-1β production at 24h. Schinus terebinthifolius is a species of plant from the Anacardiaceae family, which can be found in different regions of Brazil.

   • Selon Dos Santos da Rocha P (2018)

     Extrait Doxorubicin is an anticancer drug whose toxic effects on non-cancer cells are associated with increased oxidative stress. This study investigated the chemical composition, antioxidant activity of the methanolic extract of Schinus terebinthifolius leaves (MESL) as well as effects against doxorubicin-induced toxicity in human erythrocytes, K562 human erythroleukemia cells, & mouse hearts.

3. 3

   Periodontite, carie, plaque dentaire : Aggregatibacter actinomycetemcomitans, Streptococcus mutans, Staphylococcus aureus

   Partie usitée : Écorce. Profil pharmacologique documenté : Chloramphénicol-like, tetracycline-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pereira EMR (2011)

     Extrait This study evaluated the susceptibility of oral pathogenic microorganisms Candida albicans, Streptococcus mutans, Staphylococcus aureus, & Aggregatibacter actinomycetemcomitans to Brazilian medicinal plant extracts of Schinus terebenthifolius, Croton campestris, Lafoensia pacari (pacari), Centaurium erythraea, Stryphnodendron adstringens (barbatimão), & Anacardium humile, as compared to standardized antimicrobial agents (nystatin, chloramphenicol & tetracycline hydrochloride). This study suggests that extracts from the plants tested could be an alternative therapeutic option for infectious conditions of the oral cavity, such as denture stomatitis, dental caries, & periodontitis.

   • Selon Uliana MP (2016)

     Extrait All extracts showed strong antimicrobial activity against Staphylococcus aureus & Escherichia coli. The leaves of Schinus terebinthifolius Raddi (Anacardiaceae), the Brazilian pepper tree, are widely used in folk medicine for treating human diseases caused by microorganisms.

   • Selon Salem MZM (2018)

     Extrait The toxicity against the growth of Acinetobacter baumannii, Bacillus subtilis, Escherichia coli, Micrococcus flavus, Pseudomonas aeruginosa, Sarcina lutea, & Staphylococcus aureus was determined with measuring the inhibition zones (IZs) using the disc diffusion method at the concentrations from 125 to 2000 μg/mL, also, the minimum inhibitory concentrations (MICs) using 96-well micro-plates & ranged from 4 to 2000 μg/mL.

   • Selon Dos Santos GD (2021)

     Extrait Xylaria allantoidea CMRP1424 extracts showed antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, & Staphylococcus aureus. In this study, endophytic fungi were isolated from Schinus terebinthifolius to investigate their diversity & antimicrobial activity.

   • Selon Cole (2014)

     Extrait The antibacterial activity of the essential oil was evaluated against wild strains of hospital origin (Escherichia coli, Pseudomonas sp., Klebsiella oxytoca, Corynebacterium sp., Staphylococcus aureus, Enterobacter sp., Enterobacter agglomerans, Bacillus sp., Nocardia sp.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.