Senna obtusifolia (Soumatjé bata) : vertus médicinales en extraction alcoolique

Senna obtusifolia (Soumatjé bata, Kaka-bétjé-bata, Zépiant, Séné, Sou-marqué batârd, caca-à-béké batârd, herbe puante, stinking weed) — famille Fabacée.

Synonymes scientifiques : Cassia obtusifolia L, Senna tora var. obtusifolia (L.) X.Y. Zhu, Emelista obtusifolia (L.) Raf., Cassia tora var. obtusifolia (L.) Haines.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 11 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 34 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Troubles hépatiques :hépatite ,stéatose hépatique, cirrhose

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shihab S (2017)

     Extrait The aim of the present study to evaluate the hepatoprotective effect of S Obtusifolia seeds extract against carbon tetrachloride CCL4 induced liver damage. Generally, the results suggest that S Obtusifolia seeds acts as potent hepatoprotective agent against CCL4 induced hepatotoxicity in rats.

   • Selon Paudel P (2018)

     Extrait The protective effects of the anthraquinone & naphthopyrone glycosides against t-BHP-induced oxidative damage in human liver-derived HepG2 cells were due to the prevention of ROS generation and up-regulated activity of HO-1 via Nrf2 activation and modulation of the JNK/ERK/MAPK signaling pathway. seed is one of the most popular traditional Chinese medicine for mutagenicity, genotoxicity, hepatotoxicity, & acute inflammatory diseases.

   • Selon Ali (2021)

     Extrait CO & possesses a wide range of pharmacological properties (e.g., antidiabetic, antimicrobial, anti-inflammatory, hepatoprotective, & neuroprotective properties) a&may be used to treat Alzheimer's disease, Parkinson's disease, & cancer. Cassia obtusifolia L., of the Leguminosae family, is used as a diuretic, laxative, tonic, purgative, & natural remedy for treating headache, dizziness, constipation, tophobia, & lacrimation a&for improving eyesight.

   • Selon Jung HA (2016)

     Extrait obtusifolia & its constituents against acetylcholinesterase (AChE), butyrilcholinesterase (BChE), & β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) enzyme activity. obtusifolia seeds, was reported to have memory enhancing properties & anti-AD activity to ameliorate amyloid β-induced synaptic dysfunction.

   • Selon Shrestha S (2017)

     Extrait Cassia obtusifolia have been used to improve vision, inflammatory diseases, & as hepatoprotective agents & to promote urination from ancient times. obtusifolia-derived compounds, rubrofusarin (1), rubrofusarin 6-O-β-d-glucopyranoside (2), rubrofusarin 6-O-β-d-gentiobioside (3), nor-rubrofusarin 6-O-β-d-glucoside (4), isorubrofusarin 10-O-β-d-gentiobioside (5), & rubrofusarin 6-O-β-d-triglucoside (6) showed promising inhibitory activity against AChE/BACE1.

2. 2

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shihab S (2017)

     Extrait The aim of the present study to evaluate the hepatoprotective effect of S Obtusifolia seeds extract against carbon tetrachloride CCL4 induced liver damage. Generally, the results suggest that S Obtusifolia seeds acts as potent hepatoprotective agent against CCL4 induced hepatotoxicity in rats.

   • Selon Paudel P (2018)

     Extrait The protective effects of the anthraquinone & naphthopyrone glycosides against t-BHP-induced oxidative damage in human liver-derived HepG2 cells were due to the prevention of ROS generation and up-regulated activity of HO-1 via Nrf2 activation and modulation of the JNK/ERK/MAPK signaling pathway. seed is one of the most popular traditional Chinese medicine for mutagenicity, genotoxicity, hepatotoxicity, & acute inflammatory diseases.

   • Selon Ali (2021)

     Extrait CO & possesses a wide range of pharmacological properties (e.g., antidiabetic, antimicrobial, anti-inflammatory, hepatoprotective, & neuroprotective properties) a&may be used to treat Alzheimer's disease, Parkinson's disease, & cancer. Cassia obtusifolia L., of the Leguminosae family, is used as a diuretic, laxative, tonic, purgative, & natural remedy for treating headache, dizziness, constipation, tophobia, & lacrimation a&for improving eyesight.

   • Selon Jung HA (2016)

     Extrait obtusifolia & its constituents against acetylcholinesterase (AChE), butyrilcholinesterase (BChE), & β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) enzyme activity. obtusifolia seeds, was reported to have memory enhancing properties & anti-AD activity to ameliorate amyloid β-induced synaptic dysfunction.

   • Selon Shrestha S (2017)

     Extrait Cassia obtusifolia have been used to improve vision, inflammatory diseases, & as hepatoprotective agents & to promote urination from ancient times. obtusifolia-derived compounds, rubrofusarin (1), rubrofusarin 6-O-β-d-glucopyranoside (2), rubrofusarin 6-O-β-d-gentiobioside (3), nor-rubrofusarin 6-O-β-d-glucoside (4), isorubrofusarin 10-O-β-d-gentiobioside (5), & rubrofusarin 6-O-β-d-triglucoside (6) showed promising inhibitory activity against AChE/BACE1.

3. 3

   Troubles neurologiques : accident ischémique transitoire cerebral (AIT)

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon KIM DH (2009)

     Extrait The aim of this study was to determine the mechanism underlying the neuroprotective effects of the ethanolic extract of the seeds of Cassia obtusifolia (COE) (10 or 50mg/kg/day, p.o) on transient cerebral global ischemia induced by bilateral common carotid artery occlusion (2VO) in mice.

   • Selon KIM DH (2007)

     Extrait In the present study, we assessed the effect of the ethanolic extract of the seeds of Cassia obtusifolia (COE) on the learning and memory impairments induced by scopolamine or transient bilateral common carotid artery occlusion (2VO).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.