Senna occidentalis (Kafé-moka) : vertus médicinales en extraction alcoolique

Senna occidentalis (Kafé-moka, Zèb-piant, Café de Moka, herbe puante, Mocha coffee, stinking herb) — famille Fabacées.

Synonymes scientifiques : Cassia ciliata-Raf, C occidentalis-L.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 28 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 140 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Troubles hépatiques générés par l’alcoolisme éthylique : anormalité des paramètres sériques : cholesterol, serum total, ALP, ALT, etc

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Jafri M (1999)

     Extrait The hepatoprotective effect of aqueous-ethanolic extract (50%, v/v) of leaves of Kasondi was studied on rat liver damage induced by paracetamol & ethyl alcohol by monitoring serum transaminase (aspartate amino transferase & serum alanine amino transferase), alkaline phosphatase, serum cholesterol, serum total lipids & histopathological alterations. (Caesalpiniaceae), commonly known as 'Kasondi', is used in Unani medicine for liver ailments and is an important ingredient of several polyherbal formulations marketed for liver diseases.

   • Selon Nde AL (2022)

     Extrait Senna occidentalis (L.) Link is a plant that has been used in medicine in some African countries, Asia and America. Several parts of this plant are used for preventing or treating diabetes, haematuria, rheumatism, typhoid, asthma, hepatotoxicity, disorders of haemoglobin & leprosy.

   • Selon Haraguchi M (2003)

     Extrait The effects of 0.5%, 0.3% & 0.1% w/w concentrations of Senna occidentalis seed mixed with commercial ration were studied in 18 groups of 32 broiler chicks each, from 1 day to 49 days of age. No significant differences in the biochemical parameters in the serum were found between the control and experimental chicks, but animals treated with 0.5% So in groups FP & TL, gained less weight and chicks that received 0.3% So or 0.5% So in the ration throughout life (TL) had a larger feed conversion ratio.

   • Selon Mercer HD (1967)

     Extrait Of 5 Holstein-Friesian & 3 Brown Swiss male calves from 7 to 20 months old & of weight from 155 to 620 lb, 5 had rumen fistulae and were given dried ground stems, leaves & beans of Cassia occidentalis into the rumen. There were extensive myodegeneretaion particularly on the hind limbs, some signs of liver necrosis & hemorrhagic kidney.

   • Selon Sastry AV (2011)

     Extrait The hepatoprotective effect of aqueous extract of seeds of C occidentalis was studied on rat liver damage induced by paracetamol and by monitoring SGPT, SGOT, alkaline phosphate, total bilirubin, & histopathological alterations. Cassia occidentalis, commonly known as ‘Coffee Senna’, is used in Unani medicine for liver ailments & is an important ingredient of several polyherbal formulations marketed for liver diseases.

2. 2

   Hépatite, stéatose hépatique, cirrhose

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Nde AL (2022)

     Extrait Senna occidentalis (L.) Link is a plant that has been used in medicine in some African countries, Asia and America. Several parts of this plant are used for preventing or treating diabetes, haematuria, rheumatism, typhoid, asthma, hepatotoxicity, disorders of haemoglobin & leprosy.

   • Selon Jafri M (1999)

     Extrait The hepatoprotective effect of aqueous-ethanolic extract (50%, v/v) of leaves of Kasondi was studied on rat liver damage induced by paracetamol & ethyl alcohol by monitoring serum transaminase (aspartate amino transferase & serum alanine amino transferase), alkaline phosphatase, serum cholesterol, serum total lipids & histopathological alterations. (Caesalpiniaceae), commonly known as 'Kasondi', is used in Unani medicine for liver ailments and is an important ingredient of several polyherbal formulations marketed for liver diseases.

   • Selon Haraguchi M (2003)

     Extrait The effects of 0.5%, 0.3% & 0.1% w/w concentrations of Senna occidentalis seed mixed with commercial ration were studied in 18 groups of 32 broiler chicks each, from 1 day to 49 days of age. Besides this, degenerative changes were found in the striated skeletal muscle in the chest, in the myocardium & in the liver in the animals that received the higher concentrations of seeds.

   • Selon Sastry AV (2011)

     Extrait The hepatoprotective effect of aqueous extract of seeds of C occidentalis was studied on rat liver damage induced by paracetamol and by monitoring SGPT, SGOT, alkaline phosphate, total bilirubin, & histopathological alterations. Cassia occidentalis, commonly known as ‘Coffee Senna’, is used in Unani medicine for liver ailments & is an important ingredient of several polyherbal formulations marketed for liver diseases.

   • Selon Pranav I (2019)

     Extrait We report an unusual case of an elderly woman who presented with a hepato-encephalopathic syndrome after ingestion of Senna occidentalis and elucidate the multi-system pathophysiology of this rapidly evolving disease. Clinical presentation mimics acute liver failure, which is very difficult to attribute to this seemingly innocuous agent.

3. 3

   Cancer : traitement adjuvant du carcinome mammaire et cerebral

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kamble SS (2019)

     Extrait The methanolic extracts of Cassia occidentalis, Callistemon viminalis, Cleome viscosa & Mimosa hamata were assessed for their cytotoxic properties against a human breast cancer cell line MCF-7 by using the Sulforhodamine B (SRB) assay. Conclusion: The selected botanicals with their anti-angiogenic & antioxidant potential could be considered as natural resources in the identification of possible therapeutic agents for breast cancer.

   • Selon Sayed A (2023)

     Extrait These results suggest that the methanolic extract of CO is an excellent candidate with potential antiproliferative activity against lung cancer; however, further studies are necessary to clarify its mechanism of action. occidentalis on seven cancer cell lines, including A-549, Colo-205, Huh-7, HCT-116, PANC-1, SKOV-3, & BNL, demonstrated its selective potent cytotoxicity on lung cancer cells without affecting normal BNL cells.

   • Selon Yadav JP (2010)

     Extrait Cassia occidentalis is an annual or perennial Ayurvedic plant which is used in several traditional medicines to cure various diseases.

   • Selon Bhagat (2010)

     Extrait to evaluate the in vitro cytotoxicity & antibacterial properties of Cassia occidentalis (whole plant) via alcoholic, hydro-alcoholic, & aqueous extracts against eight human cancer cell lines from six different tissues & four bacterial strains. Results: It was observed that aqueous extract of CO (whole plant) had more potential than hydro-alcoholic & alcoholic extracts against HCT-15, SW-620, PC-3, MCF-7, SiHa, & OVCAR-5 human cancer cell lines at 100, 30, & 10 µg/ml in a dose-dependent manner.

   • Selon Calderon AI (2006)

     Extrait The SRB cytotoxicity assay was used to screen plant extracts, in a collaborative multinational OAS project involving Argentina, Bolivia, Colombia, Costa Rica, Guatemala, Nicaragua & Panama, against breast (MCF-7), lung (H-460), & central nervous system (SF-268) human cancer cell lines. The most active plants were Thevetia ahouai, Physalis viscosa, Piper jacquemontianum, Piper barbatum, Senna occidentalis, Tovomita longifolia, & Lippia cardiostegia.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.