Sesamum indicum (Jijiri) : vertus médicinales en extraction alcoolique

Sesamum indicum (Jijiri, Sésame, Sesame) — famille Pédialacées.

Synonymes scientifiques : Sesamum africanum-Tod, S orientalis-(L-)-Kuntze.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 104 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Semence. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bhuvaneswari P (2012)

     Extrait The aim of the present study was to evaluate the effect of ethanolic extract of Sesamum indicum on kidney function in Streptozotocin Nicotinamide induced diabetic rats. The above results shows that the ethanolic extract of S indicum seeds has a potential effect to control hyperglycemia in streptozotocin induced diabetic rats,.

   • Selon Sadat Ghoreishi A (2016)

     Extrait Materials & Methods: This clinical trial has been carried out on 60 type 2 diabetic patients who were randomly divided into two groups of 30 sesame seeds consumers (case) & 30 non sesame seeds consumers (control).The case group was given 60 grams sesame seeds per day for 2 months and the control group did not receive any sesame seeds. Due to the increased risk of the disease and its related complications, in addition to the harmless properties of sesame seeds, this research was aimed to study the effect of consuming sesame seeds on some biochemical factors in type 2 diabetic patients.

   • Selon Rusmarilin H (2019)

     Extrait This study was conducted to determine the bioactive components in food ingredients that have as potential natural antioxidants source, it can be used as an alternative to reduce degenerative diabetes mellitus.

   • Selon Mirmiran P (2013)

     Extrait The aim of this study was to investigate the effects of Ardeh, paste of ground unhulled sesame seeds, on lipid Methods: LDL/HDL-C ratio were determined at baseline & six weeks later. Results: - creases in serum TC, LDL-C, & other atherogenic lipid parameters and a mild increase in HDL-C also were observed during Ardeh supplementation.

   • Selon Rahman E (2019)

     Extrait Sesamum indicum has been extensively used in Bangladesh & other Indian Subcontinent as medication for various diseases including CNS disorders. It was found to have antioxidant, antitumor, antihypertensive, neuroprotective, hypoglycemic, antimicrobial, anticonvulsant and wound healing activity.

2. 2

   Cancer : traitement adjuvant du carcinome epidermoide laryngé, rhabdomyosarcome

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon SHAWKAT (2018)

     Extrait The present study was conducted to investigate the active constituents found in ethanolic extract of Sesamum indicum defatted seeds & it’s cytotoxic activity on three types of cancer cell lines (Hep-2, AMN-3, & RD) & one normal embryo rat cell line (Ref). A clear cytotoxic activity was observed after 72 hr at concentration( 1000 µg/ml) which reached (85.83%, 40.06%, &20.20%) in the cell lines respectively, while the percentage of inhibition during exposure time of 48 hrs recorded 31.03% at a concentration of 1000µg/ml for RD cells.

   • Selon Majdalawief AF (2020)

     Extrait to evaluate the potential immunomodulatory effect of an aqueous extract of Sesamum indicum seeds with regard to splenocyte proliferation, Th1/Th2 balance, macrophage function, and the cytotoxic activity of natural killer (NK) cells. Constituents of S indicum may be used as effective therapeutic agents in regulating immune reactions implicated in various infectious & non- infectious conditions including cancer.

   • Selon Liu Z (2006)

     Extrait Some plant lignans can be converted by intestinal microbiota to the mammalian lignans, enterodiol and enterolactone, which may have protective effects against hormone-related diseases such as breast cancer.

   • Selon Ghani NA (2011)

     Extrait Results of in vitro growth inhibition (GI) of sesame extract against Human larynx epidermoid carcinoma (Hep-2), Ahmed- Mohammed- Nahi-2003 (AMN-3), Rhabdomyosarcoma (RD), & normal embryo rat (Ref) cell lines demonstrated that the growth of these cells significantly decreased when compared with control cultures (untreated), & the effects were dose, as well as, time- dependent for each Hep-2, AMN-3, & Ref cells. The present study was conducted to investigate the active constituents found in ethanolic extract of Sesamum indicum defatted seeds, & studies it effects on the serum levels of lipid & cytogenetic changes in bone marrow cells in laboratory mice (in vivo).

   • Selon Kim S (2018)

     Extrait Two human colon cancer cell lines were used in this study, HT29 colon adenocarcinoma cells & HCT116 colorectal carcinoma cells. Sesame (Sesamum indicum L.) leaves (SL) are used as vegetables & traditional medicines in Asian & African countries.

3. 3

   Infection bactérienne : Klebsiella pneumonia, Salmonella typhi, Escherichia coli & Staphylococcus aureus

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ogunsola OK (2014)

     Extrait Ethanol & aqueous leaf extracts were screened for anti-microbial activities on some pathogens: Klebsiella pneumonia, Salmonella typhii, Escherichia coli & Staphylococcus aureus using different concentrations (100mg/ml, 200mg/ml& 400mg/ml). Staphylococcus aureus growth was not inhibited or restricted from growing as the extract had no activity against the microorganism.

   • Selon Shirmohammadi E (2014)

     Extrait Shirmohammadi E et al, the antibacterial activity of silver nanoparticles produced in the plant Sesamum indicum seed extract, green method against multi-drug resistant Klebsiella pneumoniae, Euro J of Experimental Biology, 4(3):197-200, 2014,.

   • Selon Raghavan Anilakumar K (2010)

     Extrait Sesame (Sesamum indicum) seeds have been grown in tropical regions throughout the world since prehistoric times. Th e antibacterial activity of seeds against Staphylococcus & Streptococcus as well as common skin fungi, such as athlete’s foot fungus has also been well recognized.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.