Stevia rebaudania (èstévia) : vertus médicinales en extraction alcoolique

Stevia rebaudania (èstévia, Stévia, stevia) — famille Asteracées.

Synonymes scientifiques : Eupatorium rebaudianum-Bertoni.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 190 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Syndrome métabolique

   Partie usitée : Feuille. Profil pharmacologique documenté : Atorvastatine-like, Glibenclamide-like, Enalapril-like. Association synergique mentionnée : association synergique avec UNCARIA TOMENTOSA- (Willd ex Roem & Schult)-DC (Écorce de tige).

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2017)

     Extrait Further, both in vitro & in vivo studies indicate that these glycosides & the extracts from SR have pharmacological and therapeutic properties, including antioxidant, antimicrobial, antihypertensive, antidiabetic, & anticancer. This work reviews the antiobesity, antihyperglycemic, antihypertensive, & antihyperlipidemic effects of the majority of glycosides & aqueous/ alcoholic extracts from the leaves, flowers, & roots of the SR.

   • Selon MOMTAZI-BOROJENI AA (2017)

     Extrait Beyond their value as sweeteners, Stevia & its glycosdies possess therapeutic effects against several diseases such as cancer, diabetes mellitus, hypertension, inflammation, cystic fibrosis, obesity & tooth decay. Stevia leaves contain steviol glycosides including stevioside, rebaudioside (A to F), steviolbioside, & isosteviol, which are responsible for the plant's sweet taste, & have commercial value all over the world as a sugar substitute in foods, beverages and medicines.

   • Selon Villegas Vílchez LF (2022)

     Extrait The objective of this in vivo study is to evaluate in five rat models the pharmacologic effects & toxicity of a commercial hydro-alcoholic extract, GlucoMedix®, derived from Stevia rebaudiana & the pentacyclic chemotype of Uncaria Tomentosa (Willd.) DC, for use as a treatment for metabolic syndrome. Daily oral doses of 250 - 1000 mg/kg were used to evaluate the treatment effects in hyperglycemic (alloxan-induced & Glibenclamide-controlled), hyperlipidemic (cholesterol-induced & Atorvastatin-controlled), & hypertensive (L-NAME-induced & Enalapril-controlled) rat models.

   • Selon Arumugam B, (2020)

     Extrait In addition to its hypoglycemic property, the plant also exhibits antibacterial, anti-inflammatory, hypotensive, antiseptic, diuretic, anti-fertility & cardiotonic properties. Diabetic & obese people with hyperglycemia who are in a condition to follow a strict diet can use stevioside as an alternative sweetener.

   • Selon Pallares A (2015)

     Extrait Full Length Research Article Recent randomized controlled trials have demonstrated the utility of stevioside and related compounds, extracted and refined from stevia leaf plant, to improve blood glucose and blood pressure in patients with type 2 diabetes. A randomized, controlled, cross-over and double-blinded study was conducted to assess the effectiveness and safety of Stevia rebaudiana leaves to reduce blood glucose and mean arterial pressure in Sahrawi patients with type 2 diabetes.

2. 2

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon PETRUS RISKY P (2017)

     Extrait The optimal dose of ethanol extract of stevia leaf & ethanol extract of bitter leaf that can decrease LPO level in mouse Diabetes Mellitus induced is 75%: 25% STSA dose ie 75 mg / kg BW stevia: 5.12 mg / kg BB sambiloto. This study was conducted to determine the optimal effectiveness of ethanol extract combination of stevia leaves & bitter leaves of oxidative stress in diabetic Mellitus rats compared in single form.

   • Selon Villegas Vílchez LF (2022)

     Extrait Daily oral doses of 250 - 1000 mg/kg were used to evaluate the treatment effects in hyperglycemic (alloxan-induced & Glibenclamide-controlled), hyperlipidemic (cholesterol-induced & Atorvastatin-controlled), & hypertensive (L-NAME-induced & Enalapril-controlled) rat models. Alloxan-induced hyperglycemia was reduced in a dose-dependent manner within 28 days or less.

   • Selon Jaitak V (2009)

     Extrait They are widely used as natural sweeteners for diabetic patients, but the long extraction procedures required & the optimisation of product yield present challenging problems.

   • Selon ABDI M (2023)

     Extrait The current study aimed to investigate the effect of Stevia rebaudiana hydroalcoholic extract on serum testosterone levels, sperm parameters, in vitro fertilization (IVF) success, & in vitro embryonic developmental potential to reach the blastocyst stage in a streptozotocin (STZ)-induced mouse model of diabetes. In this research, 30 male mice were distributed randomly into control, diabetic (streptozotocin 150 mg/kg) & diabetic + Stevia (400 mg/kg) groups.

   • Selon Shivanna N (2013)

     Extrait Results: The results showed a reduction of blood glucose, ALT & AST, & increment of insulin level in the stevia whole leaves powder & extracted polyphenols fed rats compared to control diabetic group. Stevia rebaudiana has been used for the treatment of diabetes in, for example, Brazil, although a positive effect on antidiabetic & its complications has not been unequivocally demonstrated.

3. 3

   Cancer : traitement adjuvant du carcinome péritonéal d’ascite

   Partie usitée : Feuille. Profil pharmacologique documenté : 5-Fluoro-Uracile-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Rojas E (2018)

     Extrait Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. Populations: A growing body of evidence indicates that SR is protective against malignant conversion by inhibition of DNA replication in human cancer cell growth in vitro.

   • Selon Rajesh P (2010)

     Extrait Anticancer activity of ethanolic extract of leaves of Stevia Rebaudiana was determined in the rat by induced Ehrlich’s Ascites carcinoma.

   • Selon Auteur (2017)

     Extrait Further, both in vitro & in vivo studies indicate that these glycosides & the extracts from SR have pharmacological and therapeutic properties, including antioxidant, antimicrobial, antihypertensive, antidiabetic, & anticancer. These compounds can serve as a natural & alternative treatment for diseases that are associated with metabolic syndrome, thus contributing to health promotion.

   • Selon TIWARI NK (2025)

     Extrait were treated with different concentrations of methanolic extracts i.e., 1%, 3%, 5%, 7% & 10% (v/v) with a control set & the results suggested that Ocimum tenuiflorum had stronger antiproliferative potential than Stevia rebaudiana in all the doses. In the present study, we analysed various chemical components present in the methanolic leaf extracts of both of the plants employing chromatography (GC-MS) & assessed antiproliferative activity of different doses of methanolic leaf extracts in root apical meristems of Allium cepa L.

   • Selon Peteliuk V (2021)

     Extrait rebaudiana extract & its individual glycosides, including anti-hypertensive, anti-obesity, anti-diabetic, antioxidant, anti-cancer, anti-inflammatory, & antimicrobial effects & improvement of kidney function. Many studies have suggested the benefits of Stevia extract over sugar & artificial sweeteners, but it is still not a very popular sugar substitute.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.