Swietenia mahogani (Mahogani-ti-fèy) : vertus médicinales en extraction alcoolique

Swietenia mahogani (Mahogani-ti-fèy, Mahogany-à-petite-feuille, Small-leaved mahogany) — famille Méliacées.

Synonymes scientifiques : Cedrela Mahogani-L.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 47 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Semence. Profil pharmacologique documenté : Rosiglitazone-like, Acarbose-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mahid Al-Hasan SMM (2011)

     Extrait It was observed that the EESM (ethanolic extract of S Mahogani) seeds have Hypoglycaemic effect in Alloxan treated diabetic rats but has no effect on Blood glucose level in nondiabetic rats. The result suggested that the ethanolic extract of S Mahogani seeds may be a Useful in Hypoglycaemic agent in the treatment of diabetes mellitus.

   • Selon Hasan SM (2013)

     Extrait The study was performed to compare the blood glucose lowering effect of Swietenia mahagoni seeds with an oral antidiabetic drug, rosiglitazone in experimentally induced diabetic rats. The observations and results of the present study provide information that ethanolic extract of SM seeds has hypoglycaemic effect in experimentally induced diabetic rats which requires further investigation.

   • Selon Debasis De (2011)

     Extrait Antidiabetic, antioxidative, & antihyperlipidemic activities of aqueous-methanolic (2 : 3) extract of Swietenia mahagoni seed studied in streptozotocin-induced diabetic rats. Furthermore, the seed extract corrected the levels of serum urea, uric acid, creatinine, cholesterol, triglyceride, & lipoproteins towards the control level in this experimental diabetic model.

   • Selon SMMMA H (2013)

     Extrait SMMMA H et al, Comparative study of the effect of ethanolic extract of Swietenia Mahogani seeds with Rosiglitazone on experimentally induced diabetes mellitus in rats, Bangladesh Med Res Council Bull 2013; 39: 6-10.-Abstract The study was performed to compare the blood glucose lowering effect of Swietenia Mahogani seeds with an oral antidiabetic drug, Rosiglitazone in experimentally induced diabetic rats. The observations and results of the present study provide information that ethanolic extract of S Mahogani seeds has Hypoglycaemic effect in experimentally induced diabetic rats which requires further investigation.

   • Selon WRESDIYATI T (2015)

     Extrait This ethanolic-maceration SM seed extract also showed hypoglycemic effects in hyperglycemic rats at dose from 100 to 500 mg/kgBW. The objectives of this study were to analyse & compare the bioactive compounds and α-glucosidase inhibitory effect of four different types of Swietenia Mahagoni seed extract, & to analyze the hypoglycemic activity of the greatest inhibition of α-glucosidase-extract in rats.

2. 2

   Fongique : Candida albicans, Cryptococcus neoformans

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shyam Sundar D (2013)

     Extrait The antifungal activities of the extracts were tested against Cryptococcus neoformans & Candida albicans by disc diffusion assay & broth dilution method to determine minimum inhibitory concentration. The present study was carried out to evaluate the antifungal activities of aqueous & solvent extract of Swietenia Mahogany which is used as a traditional folk medicine in India for the treatment of different infectious diseases & disorders.

   • Selon Al-alusi1 NT (s.d.)

     Extrait This study has carried out to evaluate the antibacterial effect & the interaction between Tinospora crispa & Swietenia Mahogani extracts against resistant strains of Methicillin-resistant Staphylococcus aureus (MRSA). Mahogani extracts were assayed to determine their antibacterial activity against eight clinical MRSA isolates.

   • Selon UDOUMOH AF (2011)

     Extrait Different concentrations of ethanolic extracts of Swietenia Mahogani & Carapa procera leaves were evaluated for antibacterial activity against Staphylococcus aureus ATCC25923, Escherichia coli ATCC 25922, & Pseudomonas aeruginosa ATCC 27853 using the agar well diffusion method. It was concluded that the ethanolic leaf extracts of SM & CP have antibacterial & wound healing properties.

   • Selon Sahgal G (s.d.)

     Extrait Sahgal G et al, Phytochemical & antimicrobial activity of Swietenia Mahogani crude methanolic seed extract.

   • Selon MADHUMITHA S (2016)

     Extrait MADHUMITHA S et al, PHYTOCHEMICAL ANALYSIS & ANTIBACTERIAL ACTIVITY OF SWIETENIA MAHAGONI: A HIGHLY MEDICINAL PLANT IN INDIA, Asian J Pharm Clin Res, 9(6) :62-4, 2016,.

3. 3

   Diarrhée aiguë

   Partie usitée : Semence. Profil pharmacologique documenté : Diphénoxylate-like, Atropine-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hajra S (2012)

     Extrait Mahogani seeds at the concentration (50, 100, 200 a&300 mg kg-1 b.wt., p.o) using different experimental model such as castor oïl induced diarrhea, enteropooling & gastrointestinal motility were determined by in vivo experimental models. The prolonged onset of diarrhoea, inhibition of castor oil-induced enteropooling & the suppressed propulsive movement observed in this study support the traditional claim of SMi as an antidiarrhoeal drug in the Indian system of medicine without any side effects.

   • Selon Matin-Syed A (2013)

     Extrait The present study was designed to investigate the total tannin content as secondary metabolite & to evaluate the microbiological contaminants & acute toxicity studies of ethanolic extract of Swietenia Mahagoni leaves.

   • Selon NAVEEN Y P (2015)

     Extrait the study evaluates the acute toxicity of the Swietenia Mahagoni leaf in rats of Wistar strain.

   • Selon Sahgal G (2010)

     Extrait Sahgal G et al, Brine shrimp lethality & acute oral toxicity studies on Swietenia mahagoni (Linn.) Jacq.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.